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Stem Cells, ISSN 1066-5099, 10/2009, Volume 27, Issue 10, pp. 2393 - 2404
Glioblastomas are the most common and most lethal primary brain tumor. Recent studies implicate an important role for a restricted population of neoplastic... 
Interleukin 6 | Cancer stem cells | Glioblastoma | STAT3 | APOPTOSIS | GLIOBLASTOMA-MULTIFORME | PROLIFERATION | HYPOXIA | CANCER | IL-6 | CELL & TISSUE ENGINEERING | CELL BIOLOGY | interleukin 6 | STAT3 ACTIVATION | glioblastoma | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RESISTANCE | cancer stem cells | HEMATOLOGY | EXPRESSION | Interleukin-6 - antagonists & inhibitors | Cytokine Receptor gp130 - genetics | Neoplastic Stem Cells - drug effects | Humans | Cell Survival - genetics | Neoplastic Stem Cells - immunology | Apoptosis - genetics | Transplantation, Heterologous | Receptors, Interleukin-6 - drug effects | Glioma - genetics | Signal Transduction - immunology | Brain Neoplasms - immunology | Neoplastic Stem Cells - metabolism | Tumor Cells, Cultured | RNA Interference - physiology | Growth Inhibitors - pharmacology | Interleukin-6 - metabolism | STAT3 Transcription Factor - metabolism | Cell Survival - drug effects | Cytokine Receptor gp130 - metabolism | Receptors, Interleukin-6 - genetics | RNA, Small Interfering - pharmacology | Brain Neoplasms - genetics | Glioma - immunology | Signal Transduction - genetics | Brain Neoplasms - drug therapy | Cell Survival - immunology | Animals | Signal Transduction - drug effects | Mice, Nude | Cytokine Receptor gp130 - drug effects | Graft Survival - physiology | Cell Proliferation - drug effects | Mice | Graft Survival - drug effects | Glioma - drug therapy | Receptors, Interleukin-6 - metabolism | Index Medicus | Stat3
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, pp. e41831 - e41831
mTOR inhibitors are used clinically to treat renal cancer but are not curative. Here we show that autophagy is a resistance mechanism of human renal cell... 
COMPLEX | TRANSCRIPTION FACTOR NRF2 | MULTIDISCIPLINARY SCIENCES | TARGETING AUTOPHAGY | PROGRAMMED NECROSIS | DEATH MECHANISMS | METABOLIC STRESS | MAMMALIAN-CELLS | CANCER | RENAL-CELL CARCINOMA | MOUSE MODELS | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Cell Survival - drug effects | Carcinoma, Renal Cell - pathology | Antioxidants - metabolism | Humans | Mitochondria - metabolism | Basal Metabolism - drug effects | Mitochondria - drug effects | Autophagy - drug effects | Necrosis | TOR Serine-Threonine Kinases - antagonists & inhibitors | Xenograft Model Antitumor Assays | Chloroquine - pharmacology | Animals | Cell Nucleus - metabolism | Active Transport, Cell Nucleus - drug effects | NF-E2-Related Factor 2 - metabolism | Oxidation-Reduction - drug effects | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Mice | Protein Kinase Inhibitors - pharmacology | Cell Nucleus - drug effects | TOR protein | Biotechnology | Oxidative stress | Reactive oxygen species | Syngeneic grafts | Genomics | Leukemia | Kinases | Autophagy | Antioxidants | Toxicology | Mitochondria | Cell growth | Allografts | Xenografts | Gangrene | Tumorigenesis | Inhibition | Growth factors | Cytomegalovirus | Cell survival | Bioavailability | Tumor cell lines | Dentistry | Survival | Medicine | Inhibitors | Medical prognosis | Cell lines | Hypoxia | Lymphomas | Mutation | Phagocytosis | Clear cell-type renal cell carcinoma | Kidney transplantation | Cancer | Apoptosis | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2018, Volume 506, Issue 3, pp. 619 - 625
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 15, pp. 3775 - 3783
Abstract Traumatic injury to the spinal cord causes cell death, demyelination, axonal degeneration, and cavitation resulting in functional motor and sensory... 
Advanced Basic Science | Dentistry | Hyaluronan | Transplantation | Functional recovery | Hydrogel | Spinal cord injury | Neural stem/progenitor cells | OLIGODENDROCYTE LINEAGE | DIRECTED DIFFERENTIATION | MATERIALS SCIENCE, BIOMATERIALS | RAT | ENGINEERING, BIOMEDICAL | CHITOSAN CHANNELS | GROWTH-FACTOR-AA | LOCALIZED DELIVERY | STEM/PROGENITOR CELLS | CENTRAL-NERVOUS-SYSTEM | PRECURSOR CELLS | EXPRESSION | Inflammation - pathology | Oligodendroglia - metabolism | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Rats, Wistar | Recovery of Function - drug effects | Cell Count | Neural Stem Cells - cytology | Spinal Cord Injuries - pathology | Stem Cell Transplantation | Oligodendroglia - drug effects | Female | Oligodendroglia - cytology | Spinal Cord Injuries - therapy | Wound Healing - drug effects | Cell Survival - drug effects | Hyaluronic Acid - chemistry | Neural Stem Cells - drug effects | Rats | Methylcellulose - chemistry | Animals | Cell Differentiation - drug effects | Platelet-Derived Growth Factor | Spinal Cord Injuries - physiopathology | Graft Survival - drug effects | Neural Stem Cells - metabolism | Neurosciences | Methylcellulose | Platelet-derived growth factor | Analysis | Stem cells | Cellulose | Spinal cord injuries | Hyaluronic acid | Index Medicus | Spinal cord | Hydrogels | Differentiation | Cavitation | Survival | Injuries
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, pp. e17328 - e17328
Repairing trauma to the central nervous system by replacement of glial support cells is an increasingly attractive therapeutic strategy. We have focused on the... 
GLIAL-RESTRICTED PRECURSORS | GAP-JUNCTIONS | GLUTAMATE TRANSPORTERS | OLIGODENDROCYTE PROGENITORS | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | LOCOMOTOR RECOVERY | AXONAL REGENERATION | REACTIVE ASTROCYTES | CENTRAL-NERVOUS-SYSTEM | ADULT-RAT-BRAIN | Neurons - pathology | Recovery of Function - drug effects | Humans | Motor Activity - drug effects | Stem Cells - cytology | Glial Fibrillary Acidic Protein - metabolism | Neuroglia - drug effects | Neuroglia - cytology | Cytoprotection - drug effects | Recovery of Function - physiology | Female | Astrocytes - transplantation | Neurons - drug effects | Spinal Cord Injuries - therapy | Bone Morphogenetic Proteins - pharmacology | Ciliary Neurotrophic Factor - pharmacology | Astrocytes - cytology | Astrocytes - drug effects | Cell Survival - drug effects | Rats | Rats, Sprague-Dawley | Cell Shape - drug effects | Cell Movement - drug effects | Animals | Cell Differentiation - drug effects | Stem Cells - drug effects | Spinal Cord Injuries - physiopathology | Graft Survival - drug effects | Ciliary neurotrophic factor | Bone morphogenetic proteins | Spinal cord injuries | Spinal cord | Transcription factors | Transplants & implants | Central nervous system | Recovery of function | Homeostasis | Nervous system | Transplantation | Neurosurgery | Spinal cord injury | Recovery | Proteins | Pain | Rodents | Injuries | Cell survival | Neurons | Astrocytes | Fetuses | Maintenance | Laminates | Gene expression | Survival | Trauma | Feet | Medicine | Regeneration | Adenoviruses | Morphology | Stem cells | Differentiation | Apoptosis | Osteoprogenitor cells | Axonogenesis | Therapeutic applications | Conservation | Embryos | Glial stem cells | Neuronal-glial interactions | Foot | Neural stem cells | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2013, Volume 210, Issue 11, pp. 2205 - 2221
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 09/2017, Volume 21, Issue 9, pp. 2077 - 2091
Journal Article
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, pp. 11138 - 11138
Journal Article