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FASEB Journal, ISSN 0892-6638, 06/2015, Volume 29, Issue 6, pp. 2315 - 2326
Conventional T (Tcon) cells and Foxp3(+) T-regulatory (Treg) cells are thought to have differing metabolic requirements, but little is known of mitochondrial... 
Transplant survival | Histone deacetylase | Immunometabo-lism | Immunoregulation | Immunity | MEMORY DEVELOPMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | EFFECTOR FUNCTION | immunity | transplant survival | histone deacetylase | ENHANCER FACTOR-2 MEF2 | CELL BIOLOGY | immunometabolism | INFLAMMATION | CARDIAC-HYPERTROPHY | BIOLOGY | immunoregulation | DIFFERENTIATION | EXPRESSION | MOLECULAR-MECHANISMS | LYMPHOCYTES | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Graft Survival - immunology | Reactive Oxygen Species - metabolism | Sirtuin 3 - metabolism | Gene Expression Profiling | Mitochondria - immunology | Histone Deacetylases - immunology | Mice, 129 Strain | T-Lymphocytes, Regulatory - immunology | Mitochondria - genetics | T-Lymphocytes - metabolism | Forkhead Transcription Factors - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Energy Metabolism - genetics | Transcription Factors - immunology | MEF2 Transcription Factors - immunology | Repressor Proteins - metabolism | Sirtuin 3 - genetics | Histone Deacetylases - genetics | Mice, Inbred C57BL | Oxidative Phosphorylation | Repressor Proteins - genetics | Histone Deacetylases - metabolism | Energy Metabolism - immunology | Mitochondria - metabolism | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Transcription Factors - metabolism | Sirtuin 3 - immunology | Animals | Graft Survival - genetics | Repressor Proteins - immunology | MEF2 Transcription Factors - metabolism | T-Lymphocytes - immunology | Mice, Inbred BALB C | Research Communication
Journal Article
STEM CELLS, ISSN 1066-5099, 10/2009, Volume 27, Issue 10, pp. 2393 - 2404
Glioblastomas are the most common and most lethal primary brain tumor. Recent studies implicate an important role for a restricted population of neoplastic... 
interleukin 6 | glioblastoma | cancer stem cells | STAT3 | Interleukin 6 | Cancer stem cells | Glioblastoma | APOPTOSIS | GLIOBLASTOMA-MULTIFORME | PROLIFERATION | HYPOXIA | CANCER | IL-6 | CELL & TISSUE ENGINEERING | CELL BIOLOGY | STAT3 ACTIVATION | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | RESISTANCE | HEMATOLOGY | EXPRESSION | Interleukin-6 - antagonists & inhibitors | Cytokine Receptor gp130 - genetics | Neoplastic Stem Cells - drug effects | Humans | Cell Survival - genetics | Neoplastic Stem Cells - immunology | Apoptosis - genetics | Transplantation, Heterologous | Receptors, Interleukin-6 - drug effects | Glioma - genetics | Signal Transduction - immunology | Brain Neoplasms - immunology | Neoplastic Stem Cells - metabolism | Tumor Cells, Cultured | RNA Interference - physiology | Growth Inhibitors - pharmacology | Interleukin-6 - metabolism | STAT3 Transcription Factor - metabolism | Cell Survival - drug effects | Cytokine Receptor gp130 - metabolism | Receptors, Interleukin-6 - genetics | RNA, Small Interfering - pharmacology | Brain Neoplasms - genetics | Glioma - immunology | Signal Transduction - genetics | Brain Neoplasms - drug therapy | Cell Survival - immunology | Animals | Signal Transduction - drug effects | Mice, Nude | Cytokine Receptor gp130 - drug effects | Graft Survival - physiology | Cell Proliferation - drug effects | Mice | Graft Survival - drug effects | Glioma - drug therapy | Receptors, Interleukin-6 - metabolism | Stat3
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 07/2012, Volume 12, Issue 7, pp. 1924 - 1928
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 03/2013, Volume 13, Issue 3, pp. 663 - 675
Atypical hemolytic and uremic syndrome (aHUS) is a severe disease strongly associated with genetic abnormalities in the complement alternative pathway. In... 
Acute rejection | endothelial cell damage | mutations and polymorphisms in complement alternative pathway | thrombotic microangiopathy | atypical hemolytic and uremic syndrome | renal transplantation | SURGERY | FACTOR-B | HUS | FACTOR-I | FACTOR-H-AUTOANTIBODIES | TRANSPLANTATION | KIDNEY-TRANSPLANTATION | MUTATIONS | CD46 | PREDISPOSE | MEMBRANE COFACTOR PROTEIN | Recurrence | Genetic Testing | Prognosis | Humans | Middle Aged | Male | Young Adult | Hemolytic-Uremic Syndrome - genetics | Complement Factor B - genetics | Adult | Complement System Proteins - genetics | Female | Hemolytic-Uremic Syndrome - therapy | Retrospective Studies | Complement C3 - genetics | Biomarkers - metabolism | Risk Factors | Biomarkers - analysis | Kidney Transplantation | Mutation - genetics | Fibrinogen - genetics | Graft Survival - genetics | Adolescent | Membrane Cofactor Protein - genetics | Aged | Complement Factor H - genetics | Graft Rejection - genetics | Atypical Hemolytic Uremic Syndrome | Medical research | Kidneys | Genes | Organ transplant recipients | Medicine, Experimental | Genetic research | Transplantation | Clinical trials | Mutation | Transplants & implants | Drug therapy | Biological Markers | Complement C3 | Life Sciences | Immunology | Fibrinogen | Hemolytic-Uremic Syndrome | Antigens, CD46 | Graft Survival | Complement Factor H | Complement System Proteins | Complement Factor B | Graft Rejection
Journal Article
The Journal of Pathology, ISSN 0022-3417, 01/2016, Volume 238, Issue 2, pp. 288 - 299
There is a critical shortage in the number of deceased human organs that become available for the purposes of clinical transplantation. This problem might be... 
non‐human primate | organs | xenotransplantation | genetically‐engineered | islets | pig | genetically-engineered | non-human primate | HEMATOPOIETIC-CELL TRANSPLANTATION | CARDIAC XENOGRAFT SURVIVAL | TRANSGENIC PIGS | N-GLYCOLYLNEURAMINIC ACID | GENE-KNOCKOUT PIGS | MACROPHAGE-MEDIATED CYTOTOXICITY | PATHOLOGY | TISSUE FACTOR EXPRESSION | COSTIMULATION BLOCKADE | ONCOLOGY | ENDOTHELIAL-CELLS | DECAY-ACCELERATING FACTOR | Graft Survival - immunology | Blood Coagulation Disorders - prevention & control | Humans | Complement System Proteins - immunology | Swine - genetics | Adaptive Immunity - genetics | Patient Safety | Primates | Biomedical Research - methods | Complement System Proteins - genetics | Adaptive Immunity - immunology | Genetic Engineering - methods | Animals, Genetically Modified | Transplantation Immunology - physiology | Antigens - metabolism | Clinical Trials as Topic | Inflammation - immunology | Transplantation, Heterologous - methods | Immunity, Cellular - immunology | Animals | Disaccharides - immunology | Graft Survival - genetics | Tissue and Organ Procurement - methods | Inflammation - genetics | T-Lymphocytes - immunology | Graft Rejection - immunology | Graft Rejection - genetics | Genetically modified animals | Transplantation of organs, tissues, etc | Animal genetic engineering | islets Xenotransplantation | Nonhuman primate Xenotransplantation | Pig
Journal Article
Human Gene Therapy, ISSN 1043-0342, 09/2017, Volume 28, Issue 9, pp. 757 - 765
Journal Article
Kidney International, ISSN 0085-2538, 09/2015, Volume 88, Issue 3, pp. 584 - 592
Journal Article
Xenotransplantation, ISSN 0908-665X, 05/2015, Volume 22, Issue 3, pp. 221 - 230
Journal Article