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Journal of Infection, ISSN 0163-4453, 2014, Volume 69, Issue 3, pp. 216 - 225
Summary Background An intervention for Gram-negative bloodstream infections that integrated mass spectrometry technology for rapid diagnosis with antimicrobial stewardship oversight significantly... 
Infectious Disease | Bloodstream infections | Multidrug resistant | Antimicrobial stewardship | MALDI-TOF | Rapid diagnostics | MORTALITY | ACQUIRED INFECTIONS | INFECTIOUS DISEASES | METAANALYSIS | IDENTIFICATION | DISEASES SOCIETY | IMPACT | THERAPY | HEALTH-CARE | BLOOD-STREAM INFECTIONS | ENTEROBACTERIACEAE | Humans | Middle Aged | Bacteremia - mortality | Male | Pseudomonas Infections - mortality | Gram-Negative Bacterial Infections - microbiology | Time Factors | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Escherichia coli Infections - drug therapy | Escherichia coli - enzymology | Time-to-Treatment | Bacteremia - drug therapy | Klebsiella - enzymology | Gram-Negative Bacterial Infections - drug therapy | Pseudomonas Infections - diagnosis | Survival Rate | Pseudomonas Infections - microbiology | Klebsiella Infections - diagnosis | Gram-Negative Bacterial Infections - diagnosis | Hospital Costs | Escherichia coli Infections - mortality | Pseudomonas aeruginosa - isolation & purification | beta-Lactam Resistance | Acinetobacter Infections - mortality | Klebsiella - isolation & purification | Bacteremia - microbiology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Drug Resistance, Multiple, Bacterial | Acinetobacter baumannii - isolation & purification | Adult | Female | beta-Lactamases - metabolism | Acinetobacter Infections - microbiology | Length of Stay | Escherichia coli Infections - diagnosis | Intensive Care Units | Klebsiella Infections - drug therapy | Acinetobacter Infections - diagnosis | Hospital Mortality | Pseudomonas Infections - drug therapy | Acinetobacter Infections - drug therapy | Escherichia coli Infections - microbiology | Treatment Outcome | Bacteremia - diagnosis | Klebsiella Infections - microbiology | Escherichia coli - isolation & purification | Klebsiella Infections - mortality | Aged | Gram-Negative Bacterial Infections - mortality | Drug resistance in microorganisms | Care and treatment | Mass spectrometry | Patient outcomes
Journal Article
Lancet Infectious Diseases, The, ISSN 1473-3099, 2014, Volume 14, Issue 11, pp. 1123 - 1135
Journal Article
Pediatrics (Evanston), ISSN 1098-4275, 2013, Volume 132, Issue 6, pp. 990 - 996
BACKGROUND: Fever in infants is a common clinical dilemma. The objective of this study was to present data from hospital systems across the northeast,... 
Antibiotic use | Febrile infant | Epidemiology | Escherichia coli | Bacteremia | LISTERIOSIS | NETWORK | NOTHING GOES WRONG | MANAGEMENT | GUIDELINES | YOUNGER | BLOOD CULTURE | epidemiology | SERIOUS BACTERIAL-INFECTIONS | antibiotic use | PEDIATRICS | febrile infant | bacteremia | FEVER | AGE | United States - epidemiology | Prevalence | Age Factors | Fever - microbiology | Humans | Listeriosis - diagnosis | Infant | Male | Pneumococcal Infections - diagnosis | Listeriosis - epidemiology | Streptococcus agalactiae - isolation & purification | Female | Retrospective Studies | Gram-Positive Bacterial Infections - complications | Infant, Newborn | Pneumococcal Infections - complications | Escherichia coli Infections - diagnosis | Listeriosis - complications | Risk Factors | Bacteremia - complications | Gram-Negative Bacterial Infections - complications | Streptococcal Infections - epidemiology | Bacteremia - diagnosis | Gram-Positive Bacterial Infections - diagnosis | Gram-Positive Bacterial Infections - epidemiology | Escherichia coli Infections - epidemiology | Pneumococcal Infections - epidemiology | Streptococcal Infections - diagnosis | Gram-Negative Bacterial Infections - epidemiology | Bacteremia - epidemiology | Gram-Negative Bacterial Infections - diagnosis | Streptococcal Infections - complications | Escherichia coli Infections - complications | Causes of | Infants | Research | Demographic aspects | Health aspects | Babies | Pediatrics | Pathogens | Listeria | Bacteria | Blood | Fever
Journal Article
Journal Article
Journal of Infection, ISSN 0163-4453, 2014, Volume 68, Issue 1, pp. S24 - S32
Summary Neonates are predisposed to infections during the perinatal period due to multiple exposures and a relatively compromised immune system... 
Infectious Disease | Prevention | Burden | Management | Neonatal sepsis | INFECTIOUS DISEASES | BLOOD-STREAM INFECTION | LATE-ONSET SEPSIS | FLUCONAZOLE PROPHYLAXIS | PRETERM INFANTS | RANDOMIZED CONTROLLED-TRIAL | MORTALITY-RATES | BIRTH-WEIGHT INFANTS | INTENSIVE-CARE-UNIT | INVASIVE CANDIDA INFECTIONS | B-STREPTOCOCCAL DISEASE | Humans | Gram-Positive Bacterial Infections - mortality | Sepsis - diagnosis | Candidemia - mortality | Organizational Policy | Infection Control - methods | Antifungal Agents - therapeutic use | Anti-Bacterial Agents - therapeutic use | Health Policy | Infant, Newborn | Global Health | Risk Factors | Sepsis - epidemiology | Antibiotic Prophylaxis - methods | Gram-Negative Bacterial Infections - drug therapy | Treatment Outcome | Gram-Positive Bacterial Infections - diagnosis | Candidemia - epidemiology | Candidemia - diagnosis | Gram-Positive Bacterial Infections - epidemiology | Sepsis - mortality | Candidemia - drug therapy | Sepsis - therapy | Survival Analysis | Gram-Negative Bacterial Infections - epidemiology | Gram-Negative Bacterial Infections - diagnosis | Gram-Positive Bacterial Infections - drug therapy | Gram-Negative Bacterial Infections - mortality | Infants (Newborn) | Fluconazole | Patient outcomes | Mycoses | Development and progression | Cross infection | Infants | Nosocomial infections | Indexing in process
Journal Article
American Journal of Emergency Medicine, ISSN 0735-6757, 2017, Volume 35, Issue 4, pp. 579 - 583
...) from gram-positive (GP) bloodstream infections and determining the relationship between PCT levels, infection sites, and pathogen types... 
Emergency | Positive blood culture | Procalcitonin | Bacterial species | Gram-positive bacteria | Sepsis | Gram-negative bacteria | Infection sites | DIAGNOSIS | MANAGEMENT | ANTIBIOTIC USE | GUIDELINES | MARKERS | CALCITONIN | EMERGENCY MEDICINE | SEPTIC SHOCK | SERUM PROCALCITONIN | RESPIRATORY-TRACT INFECTIONS | Enterococcus faecalis | Escherichia coli | Humans | Middle Aged | Escherichia coli Infections - blood | Male | Acinetobacter Infections - blood | Bacteremia - microbiology | Gram-Negative Bacterial Infections - microbiology | Endocarditis, Bacterial - blood | Staphylococcus haemolyticus | Burkholderia cepacia | Gram-Positive Bacterial Infections - microbiology | Aged, 80 and over | Bacteremia - blood | Endocarditis, Bacterial - microbiology | Female | Urinary Tract Infections - microbiology | Retrospective Studies | Staphylococcal Infections - microbiology | Klebsiella Infections - blood | Burkholderia Infections - microbiology | Staphylococcal Infections - blood | Staphylococcus aureus | Acinetobacter Infections - microbiology | Pneumonia, Bacterial - blood | Calcitonin - blood | Emergency Service, Hospital | Intensive Care Units | Pneumonia, Bacterial - microbiology | Escherichia coli Infections - microbiology | Biomarkers - blood | Klebsiella Infections - microbiology | Gram-Positive Bacterial Infections - blood | Enterococcus faecium | Staphylococcus hominis | Acinetobacter baumannii | Urinary Tract Infections - blood | Staphylococcus epidermidis | Catheter-Related Infections - blood | Catheter-Related Infections - microbiology | Gram-Negative Bacterial Infections - blood | Aged | Burkholderia Infections - blood | Klebsiella pneumoniae | Bacteria | Health aspects | Medical research | Medical examination | Microbiology | Emergency medicine | Analysis | Endocarditis | Medicine, Experimental | Urinary tract infections | Blood | Lupus | Klebsiella | Pathogens | Multiple sclerosis | Intensive care | Pneumonia | Bacterial infections | Disease | Laboratories | Lung cancer | Medical instruments | Infections | Arthritis | Family medical history | Urinary tract | Patients | Microorganisms | Thyroid cancer | Biomarkers | Cutoffs | Diagnostic systems
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e37281
.... Here we have developed an in vivo model of long-term bacterial biofilm infections in a pediatric totally implantable venous access port (TIVAP... 
ANTIBIOTIC-LOCK TECHNIQUE | CONTROLLED-TRIAL | DIAGNOSIS | THERAPY | BACTEREMIA | IN-VIVO | BIOLOGY | ACCESS SYSTEM | MICE | CANCER | BLOOD-STREAM INFECTIONS | Staphylococcal Infections - drug therapy | Cefazolin - therapeutic use | Gentamicins - therapeutic use | Biofilms - growth & development | Pseudomonas Infections - complications | Rats | Male | Equipment Contamination | Staphylococcal Infections - complications | Anti-Bacterial Agents - therapeutic use | Animals | Staphylococcus epidermidis | Immunosuppression - adverse effects | Catheters, Indwelling - adverse effects | Models, Animal | Pseudomonas aeruginosa | Catheterization, Central Venous - adverse effects | Escherichia coli Infections - complications | Medical research | Medical equipment | Bacterial infections | Escherichia coli | Staphylococcus aureus infections | Medicine, Experimental | Cross infection | Nosocomial infections | Health aspects | Physiological apparatus | Staphylococcus aureus | Pediatrics | Surgical implants | Bioluminescence | Medical innovations | Disseminated infection | Clinical trials | Infections | Microorganisms | E coli | Bacteria | Pathogens | Medical devices | Stability | Complications | Medical instruments | Staphylococcus infections | Disease control | Contamination | Catheters | Biofilms | Antibiotics | Colonization | Cefazolin/therapeutic use | Escherichia coli infections | Biofilms/growth & development | Central Venous/adverse effects | Life Sciences | Staphylococcal Infections/complications/drug therapy | Pseudomonas Infections/complications | Bloodstream infections | Immunosuppression/adverse effects | Bacterial biofilms | Gentamicins/therapeutic use | Catheterization | Indwelling/adverse effects | Escherichia coli Infections/complications | bacterial pathogens | Bacteriology | Microbiology and Parasitology | Animal | Models | Anti-Bacterial Agents/therapeutic use
Journal Article
BMC infectious diseases, ISSN 1471-2334, 2019, Volume 19, Issue 1, pp. 485 - 6
...s. The combination of antibiotic therapy and surgical debridement plays a key role in preventing systemic infections... 
Coinfection | Bordetella Infections - microbiology | Ulcer - diagnosis | Humans | Bordetella - isolation & purification | Bordetella Infections - drug therapy | Bordetella Infections - diagnosis | Ulcer - microbiology | Gram-Negative Bacterial Infections - microbiology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Fatal Outcome | Gram-Positive Bacterial Infections - microbiology | Necrosis - microbiology | Female | Stenotrophomonas maltophilia - isolation & purification | Necrosis - diagnosis | Gram-Positive Bacterial Infections - complications | Diabetic Foot - complications | Piperacillin, Tazobactam Drug Combination - therapeutic use | Intensive Care Units | Diabetic Foot - drug therapy | Gram-Negative Bacterial Infections - complications | Gram-Negative Bacterial Infections - drug therapy | Gram-Positive Bacterial Infections - diagnosis | Diabetic Foot - microbiology | Enterococcus faecalis - isolation & purification | Diabetic Foot - diagnosis | Aged | Gram-Negative Bacterial Infections - diagnosis | Gram-Positive Bacterial Infections - drug therapy | Case studies | Gram-negative bacterial infections | Drug therapy | Health aspects | Bordetella | Patient outcomes | Drugs | Therapy | Levofloxacin | Laboratories | Pathogenesis | Virulence | Cardiovascular disease | Infections | Vancomycin | Necrosis | Microorganisms | Vasoactive agents | Surgery | Piperacillin | Amputation | Leg ulcers | Meropenem | Complications | Medical instruments | Case reports | Piperacillin-tazobactam | Patients | Feet | Hospitals | Antibiotics | Tazobactam | Ulcers | Diagnostic software | Diagnostic systems | Diabetes | Life cycles | Antimicrobial | Susceptibility breakpoint determination | Foot ulcer, diabetic | Bordetella infection
Journal Article
JAMA pediatrics, ISSN 2168-6203, 11/2017, Volume 171, Issue 11, p. e172927
Journal Article
Biotechnology advances, ISSN 0734-9750, 2019, Volume 37, Issue 3, pp. 476 - 490
With the advancement of microbiological discovery, it is evident that many infections, particularly bloodstream infections, are polymicrobial in nature... 
Bacterial infection | Molecular diagnostics | Bloodstream infection | Fingerprinting | Polymicrobial infection | Sepsis | Broad testing | Drug resistance | Target-specific | Sequencing | ENHANCED RAMAN-SPECTROSCOPY | BROAD-RANGE PCR | ANTIBIOTIC-TREATMENT DECISIONS | IN-SITU HYBRIDIZATION | REAL-TIME PCR | IONIZATION-MASS-SPECTROMETRY | GRAM-NEGATIVE BACTERIA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | HIGH-RESOLUTION MELT | BLOOD-STREAM INFECTIONS | RAPID DETECTION | DNA, Bacterial - isolation & purification | Bacteriological Techniques - methods | Humans | Bacterial Proteins - genetics | Bacteria - genetics | Bacteria - isolation & purification | Coinfection - microbiology | Coinfection - genetics | DNA, Bacterial - genetics | Coinfection - diagnosis | Pathology, Molecular - methods | RNA, Bacterial - genetics | RNA, Bacterial - isolation & purification | Bacteria - pathogenicity | Bacterial Proteins - isolation & purification | Proteins | Bacterial infections | Emergency medicine | Digitization | Diagnosis | Nucleic acids | Health aspects | Methods | Aerospace engineering | Infections | Diagnostic systems | Etiology | Identification methods | Physical properties | Culture | molecular diagnostics | polymicrobial infection | bloodstream infection | drug resistance | broad testing | bacterial infection | fingerprinting | sepsis | target-specific | sequencing
Journal Article
Current Opinion in Infectious Diseases, ISSN 0951-7375, 04/2019, Volume 32, Issue 2, pp. 113 - 122
Journal Article