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American Journal of Emergency Medicine, ISSN 0735-6757, 2016, Volume 35, Issue 4, pp. 579 - 583
Abstract Objective The aim of this study was to evaluate procalcitonin (PCT) diagnostic accuracy in discriminating gram-negative (GN) from gram-positive (GP)... 
Emergency | Positive blood culture | Procalcitonin | Bacterial species | Gram-positive bacteria | Sepsis | Gram-negative bacteria | Infection sites | DIAGNOSIS | MANAGEMENT | ANTIBIOTIC USE | GUIDELINES | MARKERS | CALCITONIN | EMERGENCY MEDICINE | SEPTIC SHOCK | SERUM PROCALCITONIN | RESPIRATORY-TRACT INFECTIONS | Enterococcus faecalis | Escherichia coli | Humans | Middle Aged | Escherichia coli Infections - blood | Male | Acinetobacter Infections - blood | Bacteremia - microbiology | Gram-Negative Bacterial Infections - microbiology | Endocarditis, Bacterial - blood | Staphylococcus haemolyticus | Burkholderia cepacia | Gram-Positive Bacterial Infections - microbiology | Aged, 80 and over | Bacteremia - blood | Endocarditis, Bacterial - microbiology | Female | Urinary Tract Infections - microbiology | Retrospective Studies | Staphylococcal Infections - microbiology | Klebsiella Infections - blood | Burkholderia Infections - microbiology | Staphylococcal Infections - blood | Staphylococcus aureus | Acinetobacter Infections - microbiology | Pneumonia, Bacterial - blood | Calcitonin - blood | Emergency Service, Hospital | Intensive Care Units | Pneumonia, Bacterial - microbiology | Escherichia coli Infections - microbiology | Biomarkers - blood | Klebsiella Infections - microbiology | Gram-Positive Bacterial Infections - blood | Enterococcus faecium | Staphylococcus hominis | Acinetobacter baumannii | Urinary Tract Infections - blood | Staphylococcus epidermidis | Catheter-Related Infections - blood | Catheter-Related Infections - microbiology | Gram-Negative Bacterial Infections - blood | Aged | Burkholderia Infections - blood | Klebsiella pneumoniae | Bacteria | Health aspects | Medical research | Medical examination | Microbiology | Emergency medicine | Analysis | Endocarditis | Medicine, Experimental | Urinary tract infections | Blood | Klebsiella | Multiple sclerosis | Intensive care | Pneumonia | Disease | Laboratories | Lung cancer | Infections | Arthritis | Family medical history | Urinary tract | Microorganisms | Burkholderia | Lupus | Pathogens | Bacterial infections | Medical instruments | Patients | Thyroid cancer | Biomarkers | Cutoffs | Diagnostic systems
Journal Article
JAMA Pediatrics, ISSN 2168-6203, 11/2017, Volume 171, Issue 11, p. e172927
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 10/2015, Volume 59, Issue 10, pp. 6471 - 6476
Journal Article
Talanta, ISSN 0039-9140, 11/2013, Volume 116, pp. 593 - 603
Journal Article
Transfusion, ISSN 0041-1132, 03/2015, Volume 55, Issue 3, pp. 636 - 646
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2018, Volume 62, Issue 2
Iclaprim is a bacterial dihydrofolate reductase inhibitor that is currently being evaluated in two phase 3 trials for the treatment of patients with acute... 
Iclaprim | Monte Carlo simulation | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | iclaprim | Pneumococcal Infections - drug therapy | Streptococcus pneumoniae - growth & development | Anti-Bacterial Agents - blood | Vancomycin-Resistant Enterococci - drug effects | Area Under Curve | Pyrimidines - blood | Vancomycin-Resistant Enterococci - growth & development | Humans | Middle Aged | Male | Microbial Sensitivity Tests | Drug Dosage Calculations | Staphylococcal Skin Infections - drug therapy | Gram-Positive Bacterial Infections - microbiology | Adult | Female | Pneumococcal Infections - microbiology | Staphylococcal Skin Infections - blood | Streptococcus pneumoniae - drug effects | Double-Blind Method | Drug Administration Schedule | Methicillin-Resistant Staphylococcus aureus - drug effects | Pneumococcal Infections - pathology | Models, Statistical | Pyrimidines - pharmacology | Staphylococcal Skin Infections - pathology | Gram-Positive Bacterial Infections - blood | Gram-Positive Bacterial Infections - pathology | Methicillin-Resistant Staphylococcus aureus - growth & development | Pneumococcal Infections - blood | Anti-Bacterial Agents - pharmacokinetics | Pyrimidines - pharmacokinetics | Aged | Anti-Bacterial Agents - pharmacology | Gram-Positive Bacterial Infections - drug therapy | Monte Carlo Method | Staphylococcal Skin Infections - microbiology
Journal Article
Clinical Microbiology and Infection, ISSN 1198-743X, 2018, Volume 25, Issue 4, pp. 447 - 453
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 09/2013, Volume 57, Issue 9, pp. 4190 - 4196
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 32, pp. 19512 - 19526
The incidence of multidrug-resistant Enterococcus faecium hospital infections has been steadily increasing. With the goal of discovering new vaccine antigens,... 
CAPSULAR POLYSACCHARIDE | NOSOCOMIAL PATHOGEN | VANCOMYCIN-RESISTANT | LEGIONAMINIC ACID | PNEUMOCOCCAL CONJUGATE | CELL-WALL | LIPOTEICHOIC ACID | GENE-CLUSTER | BIOCHEMISTRY & MOLECULAR BIOLOGY | STAPHYLOCOCCUS-AUREUS | GENOME ANALYSIS | Fructans - chemistry | Gram-Positive Bacterial Infections - immunology | Enterococcus faecium - immunology | Immune Sera - chemistry | Bacterial Vaccines - genetics | Humans | Antigens, Bacterial - immunology | Bacterial Proteins - chemistry | Molecular Sequence Data | Teichoic Acids - chemistry | Lipopolysaccharides - immunology | Sialic Acids - chemistry | Bacterial Load - drug effects | Anti-Bacterial Agents - therapeutic use | Antibodies, Bacterial - biosynthesis | Drug Resistance, Multiple, Bacterial | Gram-Positive Bacterial Infections - microbiology | Opsonin Proteins - chemistry | Female | Vaccines, Conjugate | Bacterial Proteins - immunology | Bacterial Vaccines - biosynthesis | Sialic Acids - immunology | Antibodies, Bacterial - blood | Disease Models, Animal | Carbohydrate Sequence | Uronic Acids - immunology | Rabbits | Antigens, Bacterial - chemistry | Opsonin Proteins - immunology | Teichoic Acids - immunology | Enterococcus faecium - chemistry | Fructans - immunology | Gram-Positive Bacterial Infections - blood | Uronic Acids - chemistry | Animals | Bacterial Vaccines - administration & dosage | Bacterial Vaccines - immunology | Lipopolysaccharides - chemistry | Mice | Gram-Positive Bacterial Infections - prevention & control | Enterococcus | vaccine | carbohydrate structure | antigen | Microbiology | teichoic acid
Journal Article
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 9/2011, Volume 66, Issue 9, pp. 2119 - 2125
Objectives Gram-positive microorganisms have been the predominant pathogens in central venous catheter-related bloodstream infections (CRBSIs). Recent... 
Catheterization | Bacteraemia | Gram-negative bacterial infections | SOLID-ORGAN TRANSPLANTATION | INFECTIOUS DISEASES | BACTERIAL-INFECTIONS | RISK-FACTORS | bacteraemia | HOSPITAL-ACQUIRED INFECTIONS | catheterization | MICROBIOLOGY | DEFINITIONS | INTENSIVE-CARE-UNIT | BACTEREMIA | RESISTANCE | PHARMACOLOGY & PHARMACY | STAPHYLOCOCCUS-AUREUS | NORFLOXACIN PROPHYLAXIS | Prognosis | Prospective Studies | Humans | Middle Aged | Candidiasis - epidemiology | Male | Candidiasis - microbiology | Bacteremia - microbiology | Gram-Negative Bacterial Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Candidiasis - blood | Gram-Positive Bacterial Infections - microbiology | Bacteremia - blood | Adult | Female | Catheter-Related Infections - epidemiology | Catheterization, Central Venous - adverse effects | Catheters, Indwelling | Cross Infection - epidemiology | Risk Factors | Gram-Positive Bacterial Infections - blood | Gram-Positive Bacterial Infections - epidemiology | Regression Analysis | Catheter-Related Infections - blood | Spain - epidemiology | Catheter-Related Infections - microbiology | Cross Infection - microbiology | Sex Factors | Gram-Negative Bacterial Infections - blood | Gram-Negative Bacterial Infections - epidemiology | Bacteremia - epidemiology | Aged | Cross Infection - blood | Cohort Studies
Journal Article
Pediatrics, ISSN 0031-4005, 10/2012, Volume 130, Issue 4, pp. e821 - e828
BACKGROUND: One of the most important decisions in the treatment of osteoarticular infections is the time at which parenteral therapy can be changed to oral... 
CRP | Osteomyelitis | Acute bacterial osteomyelitis | C-reactive protein | Acute bacterial arthritis | Septic arthritis | septic arthritis | ACUTE HEMATOGENOUS OSTEOMYELITIS | VENOUS THROMBOSIS | RESISTANT STAPHYLOCOCCUS-AUREUS | ANTIBIOTIC-THERAPY | CHILDREN | osteomyelitis | METHICILLIN-RESISTANT | SKELETAL INFECTIONS | acute bacterial arthritis | ANTIMICROBIAL TREATMENT | PEDIATRICS | JOINT INFECTIONS | acute bacterial osteomyelitis | Arthritis, Infectious - drug therapy | Follow-Up Studies | Humans | Child, Preschool | Arthritis, Infectious - blood | Infant | Male | Osteomyelitis - complications | Osteomyelitis - drug therapy | Anti-Bacterial Agents - therapeutic use | C-Reactive Protein - metabolism | Time Factors | Clindamycin - administration & dosage | Female | Retrospective Studies | Child | Acute Disease | Vancomycin - administration & dosage | Drug Administration Schedule | Administration, Oral | Decision Support Techniques | Gram-Negative Bacterial Infections - drug therapy | Treatment Outcome | Biomarkers - blood | Gram-Positive Bacterial Infections - blood | Clindamycin - therapeutic use | Arthritis, Infectious - complications | Vancomycin - therapeutic use | Adolescent | Gram-Negative Bacterial Infections - blood | Infusions, Intravenous | Drug Monitoring | Gram-Positive Bacterial Infections - drug therapy | Anti-Bacterial Agents - administration & dosage | Osteomyelitis - blood | Treatment outcome | Care and treatment | Diagnosis | Health aspects | Juvenile arthritis | Proteins | Pediatrics | Therapy | Bacterial infections | Medical treatment | Clinical outcomes
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 06/2017, Volume 56, Issue 6, pp. 617 - 633
Objectives We aimed to assess linezolid pharmacokinetics in the plasma and interstitial space fluid (ISF) of patients with sepsis, diabetic foot infections or... 
IN-VIVO MICRODIALYSIS | DIABETIC FOOT INFECTIONS | VENTILATOR-ASSOCIATED PNEUMONIA | COMPASSIONATE-USE PROGRAM | TISSUE PENETRATION | PHARMACOLOGY & PHARMACY | PHARMACOKINETIC/PHARMACODYNAMIC PROFILE | STAPHYLOCOCCUS-AUREUS | CONTINUOUS-INFUSION | CYSTIC-FIBROSIS | SOFT-TISSUE | Cystic Fibrosis - blood | Anti-Bacterial Agents - blood | Linezolid - therapeutic use | Humans | Middle Aged | Critical Illness | Male | Healthy Volunteers | Microbial Sensitivity Tests | Young Adult | Adipose Tissue - metabolism | Anti-Bacterial Agents - therapeutic use | Sepsis - drug therapy | Sepsis - metabolism | Linezolid - pharmacology | Adult | Female | Bacterial Infections - drug therapy | Cystic Fibrosis - metabolism | Diabetic Foot - drug therapy | Linezolid - blood | Extracellular Fluid - metabolism | Diabetic Foot - metabolism | Diabetic Foot - blood | Models, Biological | Anti-Bacterial Agents - pharmacokinetics | Aged | Anti-Bacterial Agents - pharmacology | Sepsis - blood | Bacterial Infections - blood | Linezolid - pharmacokinetics | Cystic Fibrosis - drug therapy | Bacterial Infections - metabolism | Linezolid | Complications and side effects | Critically ill | Diabetic foot | Sepsis | Research | Pharmacokinetics | Health aspects | Studies | Multidrug resistant organisms | Antibiotics | Clinical trials | Gram-positive bacteria | Cystic fibrosis | Infections | Diabetes | Patients | Foot diseases
Journal Article