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PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 9, p. e106543
NK-lysin is an antimicrobial protein produced by cytotoxic T lymphocytes and natural killer cells. In this study, we examined the biological property of a... 
CELLS | DEFENSE | CYNOGLOSSUS-SEMILAEVIS | MULTIDISCIPLINARY SCIENCES | ANTIMICROBIAL PEPTIDE | INNATE | FISH | SYNTHETIC PEPTIDE | IDENTIFICATION | EXPRESSION | GRANULYSIN | Antimicrobial Cationic Peptides - immunology | DNA, Bacterial - metabolism | Streptococcal Infections - veterinary | Molecular Sequence Data | Flatfishes - genetics | Vibrio Infections - immunology | Antimicrobial Cationic Peptides - administration & dosage | Host-Pathogen Interactions - immunology | Vibrio - metabolism | Streptococcal Infections - genetics | Fish Proteins - genetics | Bacterial Infections - genetics | Vibrio Infections - genetics | Proteolipids - immunology | Bacterial Infections - immunology | Fish Diseases - immunology | Antimicrobial Cationic Peptides - genetics | Virus Diseases - genetics | Vibrio Infections - veterinary | Amino Acid Sequence | Proteolipids - administration & dosage | Gene Expression | Fish Diseases - microbiology | Proteolipids - genetics | Virus Diseases - immunology | Fish Proteins - immunology | Flatfishes - immunology | Pseudomonas fluorescens | Bacterial Infections - veterinary | Fish Proteins - administration & dosage | Pseudomonas Infections - genetics | Pseudomonas Infections - immunology | Sequence Homology, Amino Acid | Pseudomonas Infections - veterinary | Animals | Fish Diseases - virology | Host-Pathogen Interactions - genetics | Virus Diseases - veterinary | Streptococcal Infections - immunology | Vibrio - pathogenicity | Peptides | DNA | Aquaculture industry | Fishes | Bacteria | Bacterial genetics | Health aspects | Biological properties | Laboratories | Gram-positive bacteria | Cytotoxicity | Amino acids | Lymphocytes T | Infections | Antiinfectives and antibacterials | Degradation | Killer cells | Clonal deletion | E coli | Lymphocytes | Animal tissues | Antimicrobial peptides | Deletion | Fish | Natural killer cells | Deoxyribonucleic acid--DNA | Immune system | Biodegradation | Pathogens | Immune response | Staphylococcus infections | Marine biology | Antimicrobial agents | Gene expression | Bactericidal activity | In vivo methods and tests | Cytoplasm | Viral infections | Aquaculture | Deoxyribonucleic acid
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2016, Volume 22, Issue 11, pp. 1277 - 1284
Bacterial infection is highly prevalent in patients who have had a stroke. Despite the potential contribution of micro-aspiration in post-stroke pneumonia, we... 
MEDICINE, RESEARCH & EXPERIMENTAL | VENTILATOR-ASSOCIATED PNEUMONIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MICROBIOTA | CELL BIOLOGY | STROKE | ASPIRATION PNEUMONIA | TRAUMATIC BRAIN-INJURY | RESISTANCE | CENTRAL-NERVOUS-SYSTEM | STAPHYLOCOCCUS-AUREUS | COMPLICATIONS | DYSFUNCTION | Enterococcus faecalis | Bacteremia - immunology | Gram-Positive Bacterial Infections - immunology | Humans | Middle Aged | Male | Infarction, Middle Cerebral Artery - immunology | Pneumonia, Bacterial - metabolism | Gram-Positive Bacterial Infections - metabolism | Bacteremia - microbiology | Adrenergic beta-Antagonists - pharmacology | Urinary Tract Infections - metabolism | Bacterial Infections - immunology | Gram-Positive Bacterial Infections - microbiology | Aged, 80 and over | Female | Urinary Tract Infections - microbiology | Zonula Occludens-1 Protein - metabolism | Receptors, Adrenergic, beta - metabolism | Bacterial Infections - microbiology | Stroke - immunology | Disease Models, Animal | Permeability - drug effects | Pneumonia, Bacterial - microbiology | Specific Pathogen-Free Organisms | Blood Culture | Intestine, Small - microbiology | Computational Biology | Bacterial Translocation - immunology | Gastrointestinal Microbiome - genetics | Goblet Cells - metabolism | Bacteremia - metabolism | Animals | Sequence Analysis, RNA | Intestine, Small - cytology | Microbiota - genetics | Intestine, Small - drug effects | RNA, Ribosomal, 16S - genetics | Pneumonia, Bacterial - immunology | Aged | High-Throughput Nucleotide Sequencing | Mice | Intestine, Small - metabolism | Urinary Tract Infections - immunology | Bacterial Infections - metabolism | Goblet Cells - cytology | Stroke (Disease) | Ribosomal RNA | Bacteria, Pathogenic | Physiological aspects | Genetic aspects | Virulence (Microbiology) | Identification and classification | Stroke | Pneumonia | Bacterial infections
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 129, Issue 3, pp. 787 - 793.e6
Background CD27 is a lymphocyte costimulatory molecule that regulates T-cell, natural killer (NK) cell, B-cell, and plasma cell function, survival, and... 
Allergy and Immunology | phenotype | B cell | T cell | EBV | CD27 | immunodeficiency | hypogammaglobulinemia | natural killer cell | viremia | CD70 | T-CELL | IMMUNOLOGY | HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS | B-CELLS | MEMORY | ALLERGY | XIAP DEFICIENCY | GENERATION | DIFFERENTIATION | EXPRESSION | EPSTEIN-BARR-VIRUS | Gram-Positive Bacterial Infections - immunology | Anemia, Aplastic - virology | Humans | Male | Gram-Positive Bacterial Infections - virology | Severe Combined Immunodeficiency - physiopathology | Young Adult | Severe Combined Immunodeficiency - virology | T-Lymphocytes - metabolism | Fatal Outcome | Epstein-Barr Virus Infections - genetics | Gram-Positive Bacterial Infections - genetics | Herpesvirus 4, Human - pathogenicity | B-Lymphocytes - pathology | T-Lymphocytes - pathology | Gram-Positive Bacterial Infections - complications | Anemia, Aplastic - complications | Anemia, Aplastic - genetics | B-Lymphocytes - metabolism | Siblings | Epstein-Barr Virus Infections - physiopathology | Gram-Positive Bacterial Infections - physiopathology | Epstein-Barr Virus Infections - virology | Epstein-Barr Virus Infections - immunology | Immunity, Humoral - genetics | Cells, Cultured | Herpesvirus 4, Human - immunology | Viremia - genetics | Severe Combined Immunodeficiency - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - genetics | Mutation - genetics | Agammaglobulinemia - etiology | Anemia, Aplastic - physiopathology | Severe Combined Immunodeficiency - complications | Severe Combined Immunodeficiency - genetics | B-Lymphocytes - immunology | Viremia - virology | Pedigree | Epstein-Barr Virus Infections - complications | T-Lymphocytes - immunology | Viremia - immunology | Consanguinity | Anemia, Aplastic - immunology | Antigens | Genes | Staphylococcus aureus infections | T cells | Diseases | Virus diseases | Lymphocytes | Virus diseases in children | Medical genetics | Cross infection | Children | Tetanus | Nosocomial infections | Mitogens | Ligands | Infections | T cell receptors | Family medical history | Patients | Age | Viral infections | Fever | Immune system | CD27 antigen | Immunoglobulins | Cell survival | Viremia | Aplastic anemia | Immunodeficiency | Hypogammaglobulinemia | Lymphocytes T | Costimulator | Infection | Lymphocytes B | Plasma cells | Sepsis | Mutation | Natural killer cells | Differentiation | NK cell
Journal Article
Immunity, ISSN 1074-7613, 2007, Volume 27, Issue 4, pp. 660 - 669
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 2/2010, Volume 201, Issue 4, pp. 534 - 543
Treatment of vancomycin-resistant Enterococcus (VRE) infections is limited by the paucity of effective antibiotics. Administration of broad-spectrum... 
Messenger RNA | Commensals | Antibiotics | Interleukins | Epithelial cells | Bacteria | Infections | Mice | Small intestine | Ileum | INFECTIOUS DISEASES | COMMENSAL MICROFLORA | ROR-GAMMA-T | MICROBIOLOGY | IMMUNOLOGY | TOLL-LIKE-RECEPTOR-5 | INTESTINAL BACTERIA | ANTIBODY-PRODUCING CAPACITY | HOST-DEFENSE | NKP46(+) CELLS | COLONIZED PATIENTS | PANETH CELLS | INNATE IMMUNITY | Immunohistochemistry | Gram-Positive Bacterial Infections - immunology | Gene Expression - drug effects | Vancomycin Resistance - drug effects | Cell Count | Vancomycin Resistance - immunology | Male | Toll-Like Receptor 5 - agonists | Interleukins - metabolism | Flagellin - pharmacology | Interleukins - immunology | Gram-Positive Bacterial Infections - genetics | Female | Cytokines - genetics | Intestine, Small - immunology | Cytokines - immunology | Disease Models, Animal | Toll-Like Receptor 5 - metabolism | Immunity, Innate - drug effects | Mice, Inbred C57BL | Pancreatitis-Associated Proteins | Proteins - immunology | Toll-Like Receptor 5 - immunology | Proteins - genetics | Animals | Proteins - metabolism | Intestine, Small - cytology | Anti-Bacterial Agents - pharmacology | Enterococcus - drug effects | Intestine, Small - metabolism | Gram-Positive Bacterial Infections - drug therapy | Cytokines - biosynthesis | Enterococcal infections | Drug resistance in microorganisms | Care and treatment | Cell receptors | Physiological aspects | Research | Flagella (Microbiology)
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 06/2013, Volume 110, Issue 24, pp. E2209 - E2218
Microbial capsular antigens are effective vaccines but are chemically and immunologically diverse, resulting in a major barrier to their use against multiple... 
Carbohydrates | Animal models | Infectious diseases | Malaria | Immunotherapy | carbohydrates | UNITED-STATES | animal models | PNEUMOCOCCAL DISEASE | ACTINOMYCETEMCOMITANS | MULTIDISCIPLINARY SCIENCES | infectious diseases | malaria | DISPERSIN-B | CONJUGATE VACCINES | immunotherapy | RESISTANCE | STAPHYLOCOCCUS-AUREUS | HUMAN MONOCLONAL-ANTIBODIES | MOLECULAR-BASIS | POLYSACCHARIDE | Plasmodium berghei - immunology | Gram-Positive Bacteria - physiology | Acetylglucosamine - immunology | Plasmodium berghei - physiology | Bacterial Capsules - metabolism | Humans | Antibodies, Bacterial - pharmacology | Mycoses - microbiology | Host-Pathogen Interactions - drug effects | Gram-Negative Bacteria - immunology | Host-Pathogen Interactions - immunology | Fungi - immunology | Time Factors | Bacterial Infections - immunology | Immunoglobulin G - immunology | Fungi - physiology | Immunoglobulin G - pharmacology | Gram-Positive Bacteria - immunology | Gram-Negative Bacteria - physiology | Antibodies, Monoclonal - immunology | Bacterial Infections - microbiology | Staphylococcus aureus - metabolism | Mycoses - prevention & control | Opsonin Proteins - immunology | Antibodies, Monoclonal - pharmacology | Malaria - immunology | Mice, Inbred C57BL | Protein Binding - immunology | Malaria - prevention & control | Bacterial Infections - prevention & control | Animals | Malaria - parasitology | Survival Analysis | Antibodies, Bacterial - immunology | Staphylococcus aureus - immunology | Mice | Mycoses - immunology | Bacterial Capsules - immunology | Biological Sciences | PNAS Plus
Journal Article