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Clinical Microbiology and Infection, ISSN 1198-743X, 05/2013, Volume 19, Issue 5, pp. 474 - 479
Recent changes in the management of patients with haematological malignancies might have influenced the aetiology, characteristics, antimicrobial resistance... 
neutropenia | changing epidemiology | bloodstream infection | cancer | Antimicrobial resistance | bacteraemia | Bacteraemia | Changing epidemiology | Bloodstream infection | Cancer | Neutropenia | INFECTIOUS DISEASES | RISK-FACTORS | ESCHERICHIA-COLI | MICROBIOLOGY | EMERGENCE | VIRIDANS STREPTOCOCCI | GRAM-NEGATIVE BACILLI | THERAPY | BACTEREMIA | FLUOROQUINOLONES | SPECTRUM | EPIDEMIOLOGY | Gram-Positive Bacteria - drug effects | Humans | Middle Aged | Gram-Positive Bacterial Infections - mortality | Drug Resistance, Bacterial | Bacteremia - mortality | Male | Gram-Negative Bacteria - isolation & purification | Bacteremia - microbiology | Gram-Negative Bacterial Infections - microbiology | Neutropenia - complications | Young Adult | Gram-Positive Bacterial Infections - microbiology | Aged, 80 and over | Adult | Female | Hematologic Neoplasms - complications | Neutropenia - chemically induced | Gram-Negative Bacterial Infections - pathology | Treatment Outcome | Gram-Positive Bacterial Infections - epidemiology | Gram-Positive Bacterial Infections - pathology | Gram-Negative Bacteria - drug effects | Adolescent | Gram-Negative Bacterial Infections - epidemiology | Gram-Positive Bacteria - isolation & purification | Hematologic Neoplasms - drug therapy | Bacteremia - epidemiology | Aged | Anti-Bacterial Agents - pharmacology | Bacteremia - pathology | Gram-Negative Bacterial Infections - mortality | Fatalities | Antimicrobial agents | Infections | Drug resistance | Catheters | Index Medicus
Journal Article
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 06/2016, Volume 60, Issue 6, pp. 3743 - 3750
Journal Article
BMC Biology, ISSN 1741-7007, 05/2013, Volume 11, Issue 1, pp. 61 - 61
Background: The intestinal mucus layer plays a key role in the maintenance of host-microbiota homeostasis. To document the crosstalk between the host and... 
Goblet cells | Germ-free rats | Short chain fatty acid | KLF4 | Mucin O-glycosylation | BACTERIAL SYMBIONT | CROHNS-DISEASE | CANCER CELLS | HUMAN GUT MICROBIOTA | ULCERATIVE-COLITIS | GERM-FREE | INFLAMMATORY-BOWEL-DISEASE | IN-VIVO | BIOLOGY | GENE-EXPRESSION | BUTYRATE | Intestinal Mucosa - metabolism | Bacteroides Infections - microbiology | Humans | Goblet Cells - microbiology | Polysaccharides - biosynthesis | Bacteroides Infections - pathology | Time Factors | Gram-Positive Bacterial Infections - microbiology | Bacteroides - ultrastructure | Mucus - metabolism | Cell Differentiation | Ruminococcus - physiology | Disease Models, Animal | Signal Transduction | Colon - pathology | Acetates - metabolism | Bacteroides - physiology | Gene Expression Regulation | Rats | Glycosylation | Intestinal Mucosa - microbiology | Goblet Cells - metabolism | Colon - metabolism | Mucus - microbiology | Gram-Positive Bacterial Infections - pathology | HT29 Cells | Animals | Host-Pathogen Interactions - genetics | Germ-Free Life | Colon - microbiology | Goblet Cells - pathology | Intestinal Mucosa - pathology | Anaerobic bacteria | Polysaccharides | Gnotobiotics | Microbiota (Symbiotic organisms) | Mucins | Physiological aspects | Research | Intestinal mucosa | Bacteria | Immunization | Small intestine | Rodents | Manuscripts | Index Medicus | Life Sciences | Agricultural sciences
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2018, Volume 62, Issue 2
Iclaprim is a bacterial dihydrofolate reductase inhibitor that is currently being evaluated in two phase 3 trials for the treatment of patients with acute... 
Iclaprim | Monte Carlo simulation | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | iclaprim | Pneumococcal Infections - drug therapy | Streptococcus pneumoniae - growth & development | Anti-Bacterial Agents - blood | Vancomycin-Resistant Enterococci - drug effects | Area Under Curve | Pyrimidines - blood | Vancomycin-Resistant Enterococci - growth & development | Humans | Middle Aged | Male | Microbial Sensitivity Tests | Drug Dosage Calculations | Staphylococcal Skin Infections - drug therapy | Gram-Positive Bacterial Infections - microbiology | Adult | Female | Pneumococcal Infections - microbiology | Staphylococcal Skin Infections - blood | Streptococcus pneumoniae - drug effects | Double-Blind Method | Drug Administration Schedule | Methicillin-Resistant Staphylococcus aureus - drug effects | Pneumococcal Infections - pathology | Models, Statistical | Pyrimidines - pharmacology | Staphylococcal Skin Infections - pathology | Gram-Positive Bacterial Infections - blood | Gram-Positive Bacterial Infections - pathology | Methicillin-Resistant Staphylococcus aureus - growth & development | Pneumococcal Infections - blood | Anti-Bacterial Agents - pharmacokinetics | Pyrimidines - pharmacokinetics | Aged | Anti-Bacterial Agents - pharmacology | Gram-Positive Bacterial Infections - drug therapy | Monte Carlo Method | Staphylococcal Skin Infections - microbiology | Index Medicus
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 4/2009, Volume 63, Issue 4, pp. 785 - 794
Objectives The EBIIA (Etude épidémiologique Bactério-clinique des Infections Intra-Abdominales) study was designed to describe the clinical, microbiological... 
In vitro susceptibility | Adequate antibiotic therapy | Prognosis | Surgery | Peritonitis | INFECTIOUS DISEASES | MANAGEMENT | peritonitis | GUIDELINES | RISK | MICROBIOLOGY | IN-VITRO SUSCEPTIBILITIES | prognosis | WORLDWIDE | in vitro susceptibility | THERAPY | ENTEROCOCCUS | RESISTANT BACTERIA | PHARMACOLOGY & PHARMACY | adequate antibiotic therapy | surgery | Gram-Positive Bacteria - drug effects | Humans | Middle Aged | Cross Infection - mortality | Male | Gram-Negative Bacteria - isolation & purification | Microbial Sensitivity Tests | Young Adult | Peritonitis - pathology | Cross Infection - pathology | Peritonitis - microbiology | Aged, 80 and over | Adult | Female | France | Bacterial Infections - microbiology | Community-Acquired Infections - mortality | Cross Infection - physiopathology | Peritonitis - mortality | Bacterial Infections - physiopathology | Gram-Negative Bacteria - drug effects | Bacterial Infections - pathology | Community-Acquired Infections - pathology | Cross Infection - microbiology | Adolescent | Gram-Positive Bacteria - isolation & purification | Peritonitis - physiopathology | Aged | Anti-Bacterial Agents - pharmacology | Community-Acquired Infections - physiopathology | Community-Acquired Infections - microbiology | Bacterial Infections - mortality | Abdominal surgery | Antibiotics | Bacteria | Infections | Nosocomial infections | Drug resistance | Drug therapy | Clinical outcomes | Index Medicus
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 01/2015, Volume 55, Issue 12, pp. 2501 - 2508
Many of the beneficial and adverse effects of niacin are mediated via a G protein receptor, G protein-coupled receptor 109A/hydroxycarboxylic acid 2 receptor... 
Diacylglycerol transferase | G protein-coupled receptor 109A | Lipopolysaccharide | Hydroxycarboxylic acid 2 receptor | Triglycerides | G proteins | Sytokines | DRUG | hydroxycarboxylic acid 2 receptor | EFFICACY | HM74A | PUMA-G | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | triglycerides | KAPPA-B | NICOTINIC-ACID | GENE | PROTEIN-COUPLED RECEPTOR | MOLECULAR-IDENTIFICATION | cytokines | lipopolysaccharide | diacylglycerol transferase | Gram-Positive Bacterial Infections - immunology | Up-Regulation | Receptors, G-Protein-Coupled - metabolism | Macrophages, Peritoneal - pathology | Gram-Negative Bacterial Infections - immunology | Gram-Positive Bacterial Infections - metabolism | RNA Interference | Mycoses - metabolism | Female | Disease Models, Animal | Intra-Abdominal Fat - immunology | Receptors, Nicotinic - metabolism | Gram-Negative Bacterial Infections - pathology | Virus Diseases - immunology | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Macrophages, Peritoneal - immunology | Lipid Metabolism | Virus Diseases - metabolism | 3T3-L1 Cells | Intra-Abdominal Fat - metabolism | Gram-Negative Bacterial Infections - metabolism | Macrophage Activation | Gram-Positive Bacterial Infections - pathology | Animals | Mycoses - pathology | Virus Diseases - pathology | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice | Receptors, G-Protein-Coupled - genetics | Intra-Abdominal Fat - pathology | Macrophages, Peritoneal - metabolism | Mycoses - immunology | Receptors, Nicotinic - genetics | Cell Line, Transformed | Index Medicus
Journal Article
Infection and Immunity, ISSN 0019-9567, 2015, Volume 83, Issue 12, pp. 4487 - 4494
EfbA is a PavA-like fibronectin adhesin of Enterococcus faecalis previously shown to be important in experimental urinary tract infection. Here, we expressed... 
URINARY-TRACT-INFECTION | INFECTIOUS DISEASES | INVASION | PILI | ACE | GENE | PAVA | IMMUNOLOGY | VIRULENCE | ADHESIN | ADHERENCE | BIOFILM FORMATION | Gram-Positive Bacterial Infections - immunology | Adhesins, Bacterial - genetics | Biofilms - growth & development | Collagen Type V - immunology | Genetic Complementation Test | Endocarditis, Bacterial - pathology | Endocarditis, Bacterial - prevention & control | Escherichia coli - metabolism | Gram-Positive Bacterial Infections - microbiology | Endocarditis, Bacterial - microbiology | Binding Sites | Collagen Type V - metabolism | Enterococcus faecalis - immunology | Enterococcus faecalis - pathogenicity | Gene Expression | Immunization | Collagen Type I - metabolism | Fibronectins - immunology | Adhesins, Bacterial - administration & dosage | Enterococcus faecalis - genetics | Rats | Recombinant Proteins - genetics | Endocarditis, Bacterial - immunology | Rats, Sprague-Dawley | Collagen Type I - immunology | Fibronectins - metabolism | Recombinant Proteins - administration & dosage | Gram-Positive Bacterial Infections - pathology | Animals | Recombinant Proteins - immunology | Escherichia coli - genetics | Protein Binding | Mutation | Adhesins, Bacterial - immunology | Gram-Positive Bacterial Infections - prevention & control | Index Medicus | Bacterial Infections
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2016, Volume 60, Issue 1, pp. 252 - 257
We determined the incidence, risk factors, and outcomes of bloodstream infections (BSI) subsequent to Clostridium difficile infection (CDI). We performed a... 
CLINICAL-PRACTICE GUIDELINES | MORTALITY | AMERICA | OVERGROWTH | VANCOMYCIN | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | COLONIZATION | CRITICALLY-ILL PATIENTS | EUROPEAN-SOCIETY | DISEASES SOCIETY | Coinfection | Humans | Gram-Positive Bacterial Infections - mortality | Bacteremia - mortality | Male | Enterococcus - growth & development | Clostridium Infections - microbiology | Cross Infection - pathology | Gram-Positive Bacterial Infections - microbiology | Candidiasis - pathology | Clostridium Infections - mortality | Odds Ratio | Enterobacteriaceae - growth & development | Enterobacteriaceae Infections - microbiology | Risk Factors | Bacteremia - drug therapy | Cross Infection - drug therapy | Gram-Positive Bacterial Infections - pathology | Candida - pathogenicity | Vancomycin - therapeutic use | Cross Infection - microbiology | Enterobacteriaceae - drug effects | Enterococcus - pathogenicity | Survival Analysis | Clostridium Infections - drug therapy | Enterococcus - drug effects | Gram-Positive Bacterial Infections - drug therapy | Bacteremia - pathology | Clostridium difficile - drug effects | Enterobacteriaceae Infections - drug therapy | Multivariate Analysis | Cross Infection - mortality | Candidiasis - microbiology | Case-Control Studies | Bacteremia - microbiology | Clostridium Infections - pathology | Candidiasis - drug therapy | Metronidazole - therapeutic use | Female | Candida - growth & development | Enterobacteriaceae - pathogenicity | Enterobacteriaceae Infections - mortality | Anti-Infective Agents - therapeutic use | Candidiasis - mortality | Treatment Outcome | Enterobacteriaceae Infections - pathology | Clostridium difficile - pathogenicity | Clostridium difficile - growth & development | Aged | Candida - drug effects | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2015, Volume 11, Issue 9, pp. 1 - 20
Antibiotic resistance among enterococci and gamma-proteobacteria is an increasing problem in healthcare settings. Dense colonization of the gut by... 
DEFENSE | ESCHERICHIA-COLI | MICROBIOLOGY | MICROBIOTA | CLOSTRIDIUM-DIFFICILE | VIROLOGY | COLONIZATION RESISTANCE | BACTEREMIA | DOMINATION | MICE | ANTIBIOTIC-TREATMENT | PARASITOLOGY | PATHOGENS | Enterococcus faecium - drug effects | Enterococcus faecium - physiology | Klebsiella pneumoniae - isolation & purification | Klebsiella Infections - prevention & control | Klebsiella pneumoniae - drug effects | Vancomycin-Resistant Enterococci - drug effects | Klebsiella Infections - pathology | Vancomycin-Resistant Enterococci - growth & development | Drug Resistance, Bacterial | Colony Count, Microbial | Enterococcus faecium - isolation & purification | Intestinal Mucosa - drug effects | Feces - microbiology | Vancomycin-Resistant Enterococci - physiology | Carbapenems - pharmacology | Klebsiella pneumoniae - physiology | Gram-Positive Bacterial Infections - microbiology | Female | Anti-Bacterial Agents - adverse effects | Microbial Interactions | Specific Pathogen-Free Organisms | Mice, Inbred C57BL | Ampicillin - adverse effects | In Situ Hybridization, Fluorescence | Enteritis - pathology | Intestinal Mucosa - microbiology | Klebsiella Infections - microbiology | Fecal Microbiota Transplantation | Gram-Positive Bacterial Infections - pathology | Host-Pathogen Interactions | Animals | Gastrointestinal Microbiome - drug effects | Vancomycin-Resistant Enterococci - isolation & purification | Enteritis - microbiology | Klebsiella pneumoniae - growth & development | Anti-Bacterial Agents - pharmacology | Enterococcus faecium - growth & development | Gram-Positive Bacterial Infections - prevention & control | Enteritis - prevention & control | Intestinal Mucosa - pathology | Enterococcus | Klebsiella | Drug resistance in microorganisms | Observations | Health aspects | Index Medicus | Studies | Drinking water | Cellular biology | Antibiotics | Bacteria | Software | Colon | Nosocomial infections | Drug resistance | Experiments | Bacteriology | Cancer
Journal Article