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Immunity, ISSN 1074-7613, 07/2015, Volume 43, Issue 1, pp. 187 - 199
Journal Article
Journal Article
Neuro-Oncology, ISSN 1522-8517, 04/2016, Volume 18, Issue 4, pp. 557 - 564
Journal Article
Annals of the rheumatic diseases, ISSN 0003-4967, 2015, Volume 74, Issue 6, pp. 1058 - 1064
Journal Article
Journal Article
Science, ISSN 0036-8075, 05/2016, Volume 352, Issue 6288, pp. aad3018 - aad3018
Macrophages accumulate with glioblastoma multiforme (GBM) progression and can be targeted via inhibition of colony-stimulating factor-1 receptor (CSF-1R) to... 
B-CELLS | INSULIN | MACROPHAGE PLASTICITY | GLIOBLASTOMA | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | RECEPTOR | CENTRAL-NERVOUS-SYSTEM | CANCER | PROGRESSION | Human Umbilical Vein Endothelial Cells | Receptor, IGF Type 1 - antagonists & inhibitors | Humans | Drug Resistance, Neoplasm | Phosphatidylinositol 3-Kinases - metabolism | Pyrazines - therapeutic use | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Neoplasms, Experimental - immunology | Imidazoles - therapeutic use | Macrophages - immunology | Picolinic Acids - pharmacology | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Neoplasm Recurrence, Local - metabolism | Signal Transduction | Benzothiazoles - pharmacology | NFATC Transcription Factors - metabolism | Neoplasms, Experimental - therapy | Imidazoles - pharmacology | STAT6 Transcription Factor - metabolism | Mice, Inbred Strains | Tumor Microenvironment - immunology | Animals | Glioblastoma - immunology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Picolinic Acids - therapeutic use | Macrophages - drug effects | Benzothiazoles - therapeutic use | Mice | Glioblastoma - drug therapy | Pyrazines - pharmacology | Insulin-Like Growth Factor I - antagonists & inhibitors | Insulin-Like Growth Factor I - metabolism | Cancer therapies | Brain cancer | Tumors | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/1994, Volume 91, Issue 13, pp. 5838 - 5842
Human granulocyte-macrophage colony-stimulating factor (GM-CSF) is a pleiotropic hemopoietic growth factor and activator of mature myeloid cell function. We... 
Receptors | Cell growth | Cytokines | Myeloid leukemia | Colony stimulating factors | Neutrophils | Cell lines | Granulocyte macrophage colony stimulating factor receptors | CHO cells | Blood | leukemia | cytokines | receptors | inflammation | CYTOKINES | ACTIVATION | LIGAND-BINDING | SYNOVIAL-FLUID | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | HIGH-AFFINITY BINDING | ACQUIRED IMMUNODEFICIENCY SYNDROME | INFLAMMATION | BIOLOGICAL-ACTIVITY | GM-CSF RECEPTOR | LEUKEMIA | RECEPTORS | EXPRESSION | HUMAN NEUTROPHIL | Recombinant Proteins - metabolism | Amino Acid Sequence | Cricetinae | Mutagenesis, Site-Directed | Leukemia, Myeloid | Protein Structure, Secondary | Humans | Neutrophils - drug effects | Neutrophils - physiology | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Recombinant Proteins - biosynthesis | Recombinant Proteins - pharmacology | Cell Division - drug effects | Point Mutation | Tumor Necrosis Factor-alpha - pharmacology | Animals | Transfection | Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis | Cloning, Molecular | Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Tumor Cells, Cultured | Leukemia, Erythroblastic, Acute | CHO Cells | Thymidine - metabolism | Granulocyte-macrophage colony stimulating factor | Research | Cellular biology | Medical research | Hormones | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 08/2018, Volume 49, Issue 2, pp. 275 - 287.e5
Airway epithelial cells (AECs) secrete innate immune cytokines that regulate adaptive immune effector cells. In allergen-sensitized humans and mice, the airway... 
CSF1R | colony stimulating factor 1 | CSF1 | IgE | airway epithelial cells | asthma | airway dendritic cells | interferon regulatory factor 4 | immunoglobulin E | IRF4 | CSF1 receptor | allergic sensitization | conventional dendritic cells type 2 | cDC2 | IMMUNITY | INFLUENZA-A VIRUS | DENDRITIC CELLS | MACROPHAGES | LYMPH-NODES | ASTHMA | FLOW-CYTOMETRIC ANALYSIS | IMMUNOLOGY | HOUSE-DUST MITE | MONONUCLEAR PHAGOCYTES | LUNG INFLAMMATION | Dendritic Cells - immunology | Humans | Th2 Cells - immunology | Receptors, CCR7 - biosynthesis | Cell Movement - immunology | Immunoglobulin E - immunology | Allergens - immunology | Respiratory Mucosa - immunology | Epithelial Cells - cytology | Cell Line | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Respiratory Mucosa - cytology | Mice, Inbred C57BL | Mice, Transgenic | Lymph Nodes - cytology | Macrophage Colony-Stimulating Factor - immunology | Immunity, Innate - immunology | Dendritic Cells - classification | Interferon Regulatory Factors - immunology | Animals | Up-Regulation - immunology | Epithelial Cells - immunology | RAW 264.7 Cells | Mice | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Allergy | Allergens | Dendritic cells | Immunoglobulin E | Interferon | Biological response modifiers | Allergic reaction | CC chemokine receptors | Cdc2 protein | Leukocyte migration | Epithelial cells | Lung | Effector cells | Lymphocytes T | Lymph nodes | Respiratory tract | Colony-stimulating factor | Alveoli | Antigens | Cytokines | Colonies | CCR7 protein | Fluid | Inflammation | T cell receptors | Grants | Allergies | Asthma | Drainage | Interferon regulatory factor 4 | Ligands | Software | Chemokines | Cell migration | Interferon regulatory factor | Index Medicus
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 04/2019, Volume 10, Issue 1, pp. 1935 - 15
Despite their location at the cell surface, several receptor tyrosine kinases (RTK) are also found in the nucleus, as either intracellular domains or full... 
TARGET | LOCALIZATION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | KINASE | ENDOCYTOSIS | CSF-1 RECEPTOR | EXPRESSION | MET | Chromatin - metabolism | RNA, Small Interfering - genetics | Humans | Leukemia, Myelomonocytic, Chronic - genetics | ets-Domain Protein Elk-1 - genetics | YY1 Transcription Factor - metabolism | Leukemia, Myelomonocytic, Chronic - metabolism | Cell Membrane - chemistry | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - genetics | ets-Domain Protein Elk-1 - metabolism | Early Growth Response Protein 1 - genetics | HEK293 Cells | Macrophage Colony-Stimulating Factor - pharmacology | Cell Membrane - metabolism | Leukemia, Myelomonocytic, Chronic - pathology | Chromatin - drug effects | Cell Membrane - drug effects | Chromatin - chemistry | Fluorescent Dyes - chemistry | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Signal Transduction | Gene Expression Regulation | THP-1 Cells | Macrophage Colony-Stimulating Factor - metabolism | Macrophages - cytology | YY1 Transcription Factor - genetics | Gene Editing | Macrophages - metabolism | Histones - genetics | CRISPR-Cas Systems | Protein Binding | Macrophages - drug effects | Histones - metabolism | Primary Cell Culture | Maleimides - chemistry | Early Growth Response Protein 1 - metabolism | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | RNA, Small Interfering - metabolism | Tyrosine | Myelomonocytic leukemia | Chromatin | Transcription factors | Immunoprecipitation | EGR-1 protein | Colonies | Leukemia | Gene regulation | Macrophage colony-stimulating factor | YY1 protein | Kinases | Gene expression | Macrophages | Cell surface | Recruitment | Proteins | Domains | Monocytes | Chronic myelomonocytic leukemia | Colony-stimulating factor | Index Medicus
Journal Article
Brain, ISSN 0006-8950, 11/2015, Volume 138, Issue 11, pp. 3193 - 3205
Journal Article