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1. Full Text The Transcription Factor Tcf1 Contributes to Normal NK Cell Development and Function by Limiting the Expression of Granzymes
by Jeevan-Raj, Beena and Gehrig, Jasmine and Charmoy, Mélanie and Chennupati, Vijaykumar and Grandclément, Camille and Angelino, Paolo and Delorenzi, Mauro and Held, Werner
Cell reports (Cambridge), ISSN 2211-1247, 07/2017, Volume 20, Issue 3, pp. 613 - 626
granzyme B | NK cells | self-destruction | T cell factor 1 | Tcf1 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | Hepatocyte Nuclear Factor 1-alpha - immunology | Hepatocyte Nuclear Factor 1-alpha - genetics | Killer Cells, Natural - immunology | Granzymes - immunology | Mice | Gene Expression Regulation, Enzymologic - immunology | Granzymes - genetics | Mice, Knockout | Index Medicus
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2. Full Text Death by a thousand cuts: Granzyme pathways of programmed cell death
by Chowdhury, Dipanjan and Lieberman, Judy
Annual review of immunology, ISSN 0732-0582, 2008, Volume 26, Issue 1, pp. 389 - 420
Natural killer cell | Granule exocytosis | Serine protease | Serpin | Cytotoxic granule | Cytotoxic T lymphocyte | Granzymes - antagonists & inhibitors | Animals | Granzymes - metabolism | Humans | Signal Transduction - physiology | Mice | Granzymes - genetics | Apoptosis | Cytotoxicity, Immunologic | Index Medicus | cytotoxic T lymphocyte | granule exocytosis | natural killer cell | serine protease | serpin | cytotoxic granule
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3. Full Text Are all granzymes cytotoxic in vivo?
by Joeckel, Lars T and Bird, Phillip I
Biological chemistry, ISSN 1431-6730, 02/2014, Volume 395, Issue 2, pp. 181 - 202
cell death | extracellular granzymes | antiviral | non-cytotoxic effects | Non-cytotoxic effects | Antiviral | Cell death | Extracellular granzymes | Granzymes - antagonists & inhibitors | Virus Diseases - immunology | Species Specificity | Granzymes - metabolism | Humans | Inflammation - immunology | Granzymes - genetics | Immunity, Innate | Polymorphism, Genetic | Extracellular Matrix - enzymology | Virus Diseases - enzymology | Animals | Cytotoxins - metabolism | Granzymes - immunology | Mice | Inflammation - enzymology | Cytotoxicity, Immunologic | Cell research | Proteases | Lymphocytes | Health aspects | Index Medicus
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4. Full Text A quarter century of granzymes
by Ewen, C.L and Kane, K.P and Bleackley, R.C
Cell death and differentiation, ISSN 1350-9047, 01/2012, Volume 19, Issue 1, pp. 28 - 35
apoptosis | NK cells | granzymes | cytotoxic T cells | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | T-Lymphocytes, Cytotoxic - immunology | Perforin - genetics | History, 21st Century | History, 20th Century | Humans | Caspase 3 - metabolism | Inflammation - immunology | Granzymes - genetics | Granzymes - physiology | Killer Cells, Natural - cytology | Animals | Caspase 3 - genetics | Inflammation - genetics | Killer Cells, Natural - immunology | Mice | Perforin - immunology | Granzymes - history | Immunity - genetics | T-Lymphocytes, Cytotoxic - cytology | Apoptosis | Index Medicus | Review
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5. Full Text Granzymes in cancer and immunity
by Cullen, S.P and Brunet, M and Martin, S.J
Cell death and differentiation, ISSN 1350-9047, 04/2010, Volume 17, Issue 4, pp. 616 - 623
Granzyme A | Inflammation | Granzyme B | Granzymes | Apoptosis | Cancer | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | T-Lymphocytes, Cytotoxic - immunology | Humans | Inflammation - immunology | Granzymes - physiology | T-Lymphocytes, Cytotoxic - enzymology | Immunomodulation - physiology | Signal Transduction - immunology | Apoptosis - immunology | Neoplasms - immunology | Perforin - metabolism | Inflammation - enzymology | Immunologic Surveillance - physiology | Inflammation - physiopathology | Index Medicus
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6. Full Text Improved visualization of protein consensus sequences by iceLogo
by Helsens, Kenny and Colaert, Niklaas and Martens, Lennart and Gevaert, Kris and Vandekerckhove, Joël
Nature methods, ISSN 1548-7091, 11/2009, Volume 6, Issue 11, pp. 786 - 787
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Consensus Sequence | Granzymes - chemistry | Software | Probability Theory | Proteins - chemistry | Granzymes - metabolism | Index Medicus
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7. Full Text Granzyme B PET imaging as a predictive biomarker of immunotherapy response
by Larimer, Benjamin M and Wehrenberg-Klee, Eric and Dubois, Frank and Mehta, Anila and Kalomeris, Taylor and Flaherty, Keith and Boland, Genevieve and Mahmood, Umar
Cancer research (Chicago, Ill.), ISSN 0008-5472, 05/2017, Volume 77, Issue 9, pp. 2318 - 2327
Life Sciences & Biomedicine | Oncology | Science & Technology | T-Lymphocytes, Cytotoxic - immunology | Melanoma - diagnostic imaging | Humans | Biomarkers, Pharmacological | Positron-Emission Tomography | Granzymes - genetics | Melanoma - pathology | Granzymes - isolation & purification | T-Lymphocytes, Cytotoxic - pathology | Animals | Biopsy | Melanoma - immunology | Immunotherapy | Cell Line, Tumor | Mice | Melanoma - therapy | Therapy | Immune response | Melanoma | Positron emission | Cytotoxicity | Lymphocytes T | Patients | Anticancer properties | Granzyme B | Immune checkpoint | Lymphocytes | Imaging | Isoforms | Tomography | Biomarkers | Antitumor activity | Cancer | Tumors | Index Medicus | Predictive Biomarker | Cancer Immunotherapy | PET
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8. Full Text Delivery and therapeutic potential of human granzyme B
by Kurschus, Florian C and Jenne, Dieter E
Immunological reviews, ISSN 0105-2896, 05/2010, Volume 235, Issue 1, pp. 159 - 171
immunotoxin | apoptosis | endocytosis | serine protease | therapy | Therapy | Serine protease | Endocytosis | Immunotoxin | Apoptosis | Life Sciences & Biomedicine | Immunology | Science & Technology | Genetic Therapy | Granzymes - antagonists & inhibitors | Serpins - metabolism | Granzymes - metabolism | Humans | Recombinant Fusion Proteins - therapeutic use | Models, Molecular | Antineoplastic Agents - therapeutic use | Granzymes - genetics | Antineoplastic Agents - chemistry | T-Lymphocytes, Cytotoxic - enzymology | Killer Cells, Natural - enzymology | Protein Transport | Antineoplastic Agents - metabolism | Granzymes - chemistry | Granzymes - therapeutic use | Immunotoxins - genetics | Immunotoxins - therapeutic use | Immunotoxins - metabolism | Immunotoxins - chemistry | Protein Conformation | Perforin - metabolism | Thrombin | Health aspects | Index Medicus
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