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1. Full Text Brain Development in Heavy-Drinking Adolescents
by Squeglia, Lindsay M and Tapert, Susan F and Sullivan, Edith V and Jacobus, Joanna and Meloy, M.J and Rohlfing, Torsten and Pfefferbaum, Adolf
American Journal of Psychiatry, ISSN 0002-953X, 06/2015, Volume 172, Issue 6, pp. 531 - 542
Objective:Heavy alcohol use during adolescence may alter the trajectory of normal brain development. The authors measured within-subject changes in regional... 
WOMEN | ATLAS-BASED PARCELLATION | ALCOHOLIC MEN | DRUG-USE | ADULTHOOD | CORTEX | MRI | PSYCHIATRY | RELIABILITY | MATURATION | CHILDHOOD | Neocortex - pathology | Age Factors | Humans | Cerebral Cortex - pathology | Male | Gray Matter - drug effects | Young Adult | Neocortex - drug effects | Ethanol - adverse effects | Female | Cerebral Cortex - drug effects | Child | Pons - pathology | Pons - drug effects | White Matter - drug effects | Corpus Callosum - drug effects | White Matter - pathology | Brain - drug effects | Organ Size - drug effects | Corpus Callosum - pathology | Adolescent | Gray Matter - pathology | Brain - pathology | Brain Mapping | Alcohol-Related Disorders - physiopathology | Longitudinal Studies | alcohol | brain development | adolescent | longitudinal | mixed linear effects | prospective
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2. Full Text The Effect of Antipsychotic Treatment on Cortical Gray Matter Changes in Schizophrenia: Does the Class Matter? A Meta-analysis and Meta-regression of Longitudinal Magnetic Resonance Imaging Studies
by Vita, Antonio and De Peri, Luca and Deste, Giacomo and Barlati, Stefano and Sacchetti, Emilio
Biological Psychiatry, ISSN 0006-3223, 2015, Volume 78, Issue 6, pp. 403 - 412
Abstract Background Deficits in cortical gray matter (GM) have been found in patients with schizophrenia, with evidence of progression over time. The aim of... 
Psychiatry | Schizophrenia | Structural brain changes | Magnetic resonance imaging | First generation antipsychotics | Cortical gray matter | Second generation antipsychotics | HALOPERIDOL | PSYCHIATRY | NEUROSCIENCES | 1ST-EPISODE SCHIZOPHRENIA | ATYPICAL ANTIPSYCHOTICS | NERVE GROWTH-FACTOR | SUPERIOR TEMPORAL SUBREGIONS | TWINS DISCORDANT | 2ND-GENERATION ANTIPSYCHOTICS | TARDIVE-DYSKINESIA | PROGRESSIVE BRAIN CHANGES | VOLUME LOSS | Antipsychotic Agents - adverse effects | Humans | Cerebral Cortex - pathology | Male | Schizophrenia - pathology | Gray Matter - drug effects | Antipsychotic Agents - administration & dosage | Young Adult | Magnetic Resonance Imaging | Regression Analysis | Adolescent | Gray Matter - pathology | Adult | Female | Cerebral Cortex - drug effects | Schizophrenia - drug therapy | Longitudinal Studies | Antipsychotic drugs
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3. Full Text Long-term effects of cannabis on brain structure
by Battistella, Giovanni and Fornari, Eleonora and Annoni, Jean-Marie and Chtioui, Haithem and Dao, Kim and Fabritius, Marie and Favrat, Bernard and Mall, Jean-Frédéric and Maeder, Philippe and Giroud, Christian
Neuropsychopharmacology, ISSN 0893-133X, 2014, Volume 39, Issue 9, pp. 2041 - 2048
The dose-dependent toxicity of the main psychoactive component of cannabis in brain regions rich in cannabinoid CB1 receptors is well known in animal studies.... 
ATROPHY | PSYCHIATRY | VOLUME | NEUROSCIENCES | MARIJUANA USE | DECISION-MAKING | MEMORY | ADOLESCENTS | MATTER ALTERATIONS | PHARMACOLOGY & PHARMACY | USERS | GRAY-MATTER | TEMPORAL POLE | Marijuana Smoking - adverse effects | Cannabis - adverse effects | Humans | Marijuana Abuse - pathology | Male | Brain - growth & development | Gray Matter - drug effects | Brain - drug effects | Young Adult | Magnetic Resonance Imaging | Image Processing, Computer-Assisted | Time Factors | Adolescent | Age of Onset | Gray Matter - pathology | Brain - pathology | Adult | Surveys and Questionnaires | Index Medicus | Original
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4. Full Text Long-chain omega-3 fatty acids improve brain function and structure in older adults
by Witte, A. Veronica and Kerti, Lucia and Hermannstädter, Henrike M and Fiebach, Jochen B and Schreiber, Stephan J and Schuchardt, Jan Philipp and Hahn, Andreas and Flöel, Agnes
Cerebral Cortex, ISSN 1047-3211, 11/2014, Volume 24, Issue 11, pp. 3059 - 3068
Higher intake of seafish or oil rich in long-chain omega-3 polyunsaturated fatty acids (LC-n3-FA) may be beneficial for the aging brain. We tested in a... 
diffusion tensor imaging | voxel-based morphometry | executive functions | intima media thickness | cognitive aging | INTIMA-MEDIA THICKNESS | WHITE-MATTER | ALZHEIMERS-DISEASE | HUMAN-MEMORY | ARACHIDONIC-ACID | MILD COGNITIVE IMPAIRMENT | VAL66MET POLYMORPHISM | NEUROSCIENCES | INSULIN-RECEPTOR | DOCOSAHEXAENOIC ACID | DIFFUSION | Prospective Studies | Brain - anatomy & histology | Anthropometry | Cholesterol - blood | Humans | Middle Aged | Aging - drug effects | Male | Brain - physiology | Gray Matter - drug effects | Psychiatric Status Rating Scales | Fasting - blood | Fatty Acids, Omega-3 - pharmacology | Female | Double-Blind Method | Carotid Intima-Media Thickness | White Matter - drug effects | Lipoproteins - blood | Cognition - drug effects | Aging - blood | Brain - drug effects | Neuropsychological Tests | Magnetic Resonance Imaging | Analysis of Variance | Image Processing, Computer-Assisted | Aged
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5. Full Text Grey matter OPCs are less mature and less sensitive to IFNγ than white matter OPCs: Consequences for remyelination
by Lentferink, Dennis H and Jongsma, Jacomien M and Werkman, Inge and Baron, Wia
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 2113 - 15
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by the formation of demyelinated lesions in the central nervous system. At later stages... 
TUMOR-NECROSIS-FACTOR | MULTIPLE-SCLEROSIS | INTERFERON-GAMMA | MULTIDISCIPLINARY SCIENCES | CORTICAL REMYELINATION | CNS | CENTRAL-NERVOUS-SYSTEM | MONOCLONAL-ANTIBODY | DIFFERENTIATION | OLIGODENDROCYTE PROGENITOR CELLS | FACTOR-ALPHA | Antiviral Agents - pharmacology | Cells, Cultured | Rats | White Matter - drug effects | Stem Cells - cytology | Gray Matter - drug effects | Gray Matter - cytology | Animals | Oligodendroglia - drug effects | Cell Differentiation - drug effects | Remyelination - physiology | Nerve Regeneration - drug effects | Stem Cells - drug effects | Oligodendroglia - cytology | Remyelination - drug effects | Interferon-gamma - pharmacology | White Matter - cytology | Neonates | Multiple sclerosis | Myelin | Central nervous system | Tumor necrosis factor-α | Substantia alba | Gene expression | Substantia grisea | Glial stem cells | Progenitor cells | Regeneration | Myelination | Neurodegeneration | Neurological complications | γ-Interferon | Oligodendrocytes | Cell migration
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6. Full Text Myelin Loss and Axonal Ion Channel Adaptations Associated with Gray Matter Neuronal Hyperexcitability
by Hamada, Mustafa S and Kole, Maarten H. P
Journal of neuroscience, ISSN 0270-6474, 2015, Volume 35, Issue 18, pp. 7272 - 7286
Myelination and voltage-gated ion channel clustering at the nodes of Ranvier are essential for the rapid saltatory conduction of action potentials. Whether... 
Node of Ranvier | Nav1.6 | Axon | Axon initial segment | Demyelination | Kv7.3 | SEGMENT | SODIUM-CHANNELS | ACTION-POTENTIAL INITIATION | MECHANISMS | node of Ranvier | NEUROSCIENCES | axon initial segment | MAINTENANCE | PYRAMIDAL NEURONS | NEOCORTEX | MULTIPLE-SCLEROSIS | demyelination | DEMYELINATED AXONS | CONDUCTION | axon | Cuprizone - toxicity | Neurons - pathology | Myelin Sheath - physiology | Myelin Sheath - pathology | Mice, Inbred C57BL | Nerve Fibers, Myelinated - drug effects | Axons - drug effects | Myelin Sheath - drug effects | Male | Axons - physiology | Ion Channels - physiology | Gray Matter - drug effects | Animals | Nerve Fibers, Myelinated - pathology | Axons - pathology | Gray Matter - pathology | Nerve Fibers, Myelinated - physiology | Neurons - physiology | Demyelinating Diseases - chemically induced | Mice | Gray Matter - physiology | Demyelinating Diseases - pathology | Neurons - drug effects
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7. Full Text Adolescent Development of Cortical and White Matter Structure in the NCANDA Sample: Role of Sex, Ethnicity, Puberty, and Alcohol Drinking
by Pfefferbaum, Adolf and Rohlfing, Torsten and Pohl, Kilian M and Lane, Barton and Chu, Weiwei and Kwon, Dongjin and Nolan Nichols, B and Brown, Sandra A and Tapert, Susan F and Cummins, Kevin and Thompson, Wesley K and Brumback, Ty and Meloy, M.J and Jernigan, Terry L and Dale, Anders and Colrain, Ian M and Baker, Fiona C and Prouty, Devin and De Bellis, Michael D and Voyvodic, James T and Clark, Duncan B and Luna, Beatriz and Chung, Tammy and Nagel, Bonnie J and Sullivan, Edith V
Cerebral Cortex, ISSN 1047-3211, 10/2016, Volume 26, Issue 10, pp. 4101 - 4121
Brain structural development continues throughout adolescence, when experimentation with alcohol is often initiated. To parse contributions from biological and... 
cortex | adolescence | development | ethnicity | sex | SURFACE-AREA | LONGITUDINAL CHANGES | NEUROSCIENCES | SYNAPTIC DENSITY | INCIDENTAL FINDINGS | ATLAS-BASED PARCELLATION | HUMAN CEREBRAL-CORTEX | IN-VIVO | ADULT HUMAN BRAIN | MAGNETIC-RESONANCE | SOCIOECONOMIC-STATUS | Humans | White Matter - growth & development | Gray Matter - growth & development | Male | Gray Matter - drug effects | Young Adult | Ethnic Groups | Female | Cerebral Cortex - drug effects | Child | Puberty | Alcohol Drinking - pathology | Cross-Sectional Studies | Incidental Findings | Organ Size | White Matter - drug effects | Adolescent Development - drug effects | Sex Characteristics | Cerebral Cortex - diagnostic imaging | Gray Matter - diagnostic imaging | Magnetic Resonance Imaging | White Matter - diagnostic imaging | Image Processing, Computer-Assisted | Adolescent | Cerebral Cortex - growth & development | Cohort Studies | Original
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8. Full Text Cannabis and alcohol use, and the developing brain
by Meruelo, A.D and Castro, N and Cota, C.I and Tapert, S.F
Behavioural Brain Research, ISSN 0166-4328, 05/2017, Volume 325, Issue Pt A, pp. 44 - 50
Sex hormones and white (and grey) matter in the limbic system, cortex and other brain regions undergo changes during adolescence. Some of these changes include... 
Neuroimaging | Adolescence | Cannabis | Positron emission tomography (PET) | Developing brain | Alcohol | Neuropsychological studies | Blood oxygen dependent level (BOLD) | GRAY | ADOLESCENT MARIJUANA USERS | VOLUME | MATURATION | NEUROSCIENCES | HEAVY-DRINKING | CHILDREN | CORTICAL THICKNESS | SPATIAL WORKING-MEMORY | BEHAVIORAL SCIENCES | FMRI RESPONSE | WHITE-MATTER DEVELOPMENT | Marijuana Smoking - adverse effects | Cannabis - adverse effects | Humans | Attention | White Matter - growth & development | White Matter - drug effects | Gray Matter - growth & development | Adolescent Development - drug effects | Brain - growth & development | Sex Characteristics | Alcohol Drinking - adverse effects | Brain - physiology | Gray Matter - drug effects | Brain - drug effects | Ethanol - adverse effects | Adolescent | Micro-Electrical-Mechanical Systems | Brain | Brain research | Drugs and youth | Neurons | Marijuana | Hormones, Sex | Drinking of alcoholic beverages | alcohol | neuropsychological studies | blood oxygen dependent level (BOLD) | developing brain | positron emission tomography (PET) | cannabis | adolescence | neuroimaging
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9. Full Text Prenatal cocaine effects on brain structure in early infancy
by Grewen, Karen and Burchinal, Margaret and Vachet, Clement and Gouttard, Sylvain and Gilmore, John H and Lin, Weili and Johns, Josephine and Elam, Mala and Gerig, Guido
NeuroImage, ISSN 1053-8119, 11/2014, Volume 101, pp. 114 - 123
Prenatal cocaine exposure (PCE) is related to subtle deficits in cognitive and behavioral function in infancy, childhood and adolescence. Very little is known... 
Prenatal cocaine | Magnetic resonance imaging | Prenatal substance abuse | Infant brain development | CSF enlargement | Cortical gray matter | WHITE-MATTER | MICROTUBULE-ASSOCIATED PROTEIN-2 | NEUROSCIENCES | NEUROIMAGING | DRUG EXPOSURE | SCHOOL-AGED CHILDREN | ADOLESCENTS | EXPOSED IN-UTERO | MAGNETIC-RESONANCE | INHIBITORY CONTROL | CEREBRAL-BLOOD-FLOW | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | GRAY-MATTER | Smoking - adverse effects | Dopamine Uptake Inhibitors - adverse effects | Brain - anatomy & histology | Cannabis - adverse effects | Cerebrospinal Fluid | Humans | Serotonin Uptake Inhibitors - adverse effects | Gray Matter - growth & development | Male | Brain - growth & development | Alcohol Drinking - adverse effects | Gray Matter - drug effects | Narcotics - adverse effects | Brain - drug effects | Pregnancy | Magnetic Resonance Imaging | Gray Matter - anatomy & histology | Frontal Lobe - drug effects | Frontal Lobe - growth & development | Female | Cocaine - adverse effects | Frontal Lobe - anatomy & histology | Infant, Newborn | Prenatal Exposure Delayed Effects - chemically induced | Brain | Serotonin uptake inhibitors | Cocaine | Pregnant women | Analysis | Babies | Prenatal development | Child development | Children & youth | magnetic resonance imaging | prenatal substance abuse | infant brain development | cortical gray matter | prenatal cocaine
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10. Full Text Lesion remyelinating activity of GSK239512 versus placebo in patients with relapsing-remitting multiple sclerosis: a randomised, single-blind, phase II study
by Schwartzbach, Caryl J and Grove, Richard A and Brown, Robert and Tompson, Debra and Then Bergh, Florian and Arnold, Douglas L
Journal of Neurology, ISSN 0340-5354, 2/2017, Volume 264, Issue 2, pp. 304 - 315
Histamine H3 receptor blockade may enhance lesion remyelination in multiple sclerosis (MS). The efficacy (using a magnetic resonance imaging marker of... 
Neurology | Neurosciences | Medicine & Public Health | Magnetic resonance imaging | GSK239512 | Relapsing-remitting multiple sclerosis | Magnetisation transfer ratio | Neuroradiology | Remyelination | TRIALS | H-3 RECEPTOR ANTAGONIST | MAGNETIZATION-TRANSFER RATIO | MODERATE ALZHEIMERS-DISEASE | CLINICAL NEUROLOGY | IMPAIRMENT | RESONANCE | IN-VIVO | DIFFERENTIATION | LONGITUDINAL ANALYSIS | BRAIN | Neuroprotective Agents - therapeutic use | Single-Blind Method | Brain - diagnostic imaging | Adjuvants, Immunologic - administration & dosage | Glatiramer Acetate - administration & dosage | Benzazepines - adverse effects | Humans | Middle Aged | Myelin Sheath - drug effects | Male | Histamine Antagonists - therapeutic use | Gray Matter - drug effects | Histamine Antagonists - adverse effects | Young Adult | Drug Therapy, Combination - adverse effects | Adult | Female | Neuroprotective Agents - adverse effects | Double-Blind Method | Multiple Sclerosis, Relapsing-Remitting - drug therapy | White Matter - drug effects | Injections, Intramuscular | Gray Matter - diagnostic imaging | Brain - drug effects | Magnetic Resonance Imaging | Interferon beta-1a - administration & dosage | White Matter - diagnostic imaging | Multiple Sclerosis, Relapsing-Remitting - psychology | Benzazepines - therapeutic use | Multiple Sclerosis, Relapsing-Remitting - diagnostic imaging | Multiple sclerosis | Care and treatment | Research | Original Communication
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