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Journal of Biological Chemistry, ISSN 0021-9258, 11/2008, Volume 283, Issue 48, pp. 33483 - 33497
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, p. e0143518
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 5835
The arachidonic acid metabolism (AAM) pathway promotes tumour progression. Chemical inhibitors of AAM pathway prolong post-treatment survival of cancer... 
COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | SQUAMOUS-CELL CARCINOMA | PHOSPHOLIPASE A | ONCOGENIC TRANSFORMATION | OVARIAN-CANCER | TUMOR-ANGIOGENESIS | RECEPTOR TYROSINE KINASE | NECK-CANCER | INHIBITION INDUCED APOPTOSIS | Group IV Phospholipases A2 - genetics | Thromboxane-A Synthase - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Cytochrome P-450 Enzyme System - metabolism | Group III Phospholipases A2 - genetics | Carcinoma, Squamous Cell - surgery | Group VI Phospholipases A2 - metabolism | Cytochrome P450 Family 2 | Arachidonic Acids - metabolism | Carcinoma, Squamous Cell - mortality | Group IV Phospholipases A2 - metabolism | Arachidonic Acids - genetics | Group VI Phospholipases A2 - genetics | Peroxidases - metabolism | Mouth Neoplasms - genetics | Group III Phospholipases A2 - metabolism | Gene Expression | Proportional Hazards Models | Cytochrome P-450 CYP2C19 - genetics | Treatment Outcome | gamma-Glutamyltransferase - metabolism | Mouth Neoplasms - mortality | Metabolic Networks and Pathways - genetics | gamma-Glutamyltransferase - genetics | Mouth Neoplasms - surgery | Survival Analysis | Cytochrome P-450 Enzyme System - genetics | Mouth Neoplasms - pathology | Thromboxane-A Synthase - metabolism | Cytochrome P-450 CYP2C19 - metabolism | Mutation | Peroxidases - genetics
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2009, Volume 421, Issue 1, pp. 17 - 27
PLA2 (phospholipase A2) group III is an atypical sPLA2 (secretory PLA2) that is homologous with bee venom PLA2 rather than with other mammalian sPLA2s. In the... 
Phospholipid | Splenomegaly | Transgenic mouse | Phospholipase A2 | Prostaglandin | Dermatitis | Group III Phospholipases A2 - metabolism | Dermatitis - pathology | Inflammation - metabolism | Animals | Dermatitis - genetics | Group III Phospholipases A2 - genetics | Mice, Transgenic | Mice | Gene Expression Regulation, Enzymologic - physiology | Skin - pathology | Dermatitis - metabolism | BRAK, breast- and kidney-expressed chemokine | WT, wild-type | phospholipase A2 | PGE2, prostaglandin E2 | mPGES, microsomal prostaglandin E synthase | cPLA2, cytosolic PLA2 | RT, reverse transcription | ESI, electrospray ionization | transgenic mouse | MPO, myeloperoxidase | dermatitis | MCP-1, monocyte chemoattractant protein-1 | PAF, platelet-activating factor | LDL, low-density lipoprotein | TNFα, tumour necrosis factor α | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | IFN, interferon | PC, phosphatidylcholine | sPLA2, secretory PLA2 | COX, cyclo-oxygenase | PAS, periodic acid–Schiff | prostaglandin | PLA2G2A (etc.), sPLA2 group IIA (etc.) | PLA2, phospholipase A2 | CAG, chicken β-actin | LTB4, leukotriene B4 | NK, natural killer | IL, interleukin | mMCP, mouse mast cell protease | LPS, lipopolysaccharide | HDC, histidine decarboxylase | LNL, LoxP–neomycin-resistance gene–LoxP | phospholipid | Tg, transgenic | splenomegaly | HDL, high-density lipoprotein
Journal Article
Nature immunology, ISSN 1529-2908, 06/2013, Volume 14, Issue 6, pp. 554 - 563
Journal Article
Carcinogenesis, ISSN 0143-3334, 03/2010, Volume 31, Issue 3, pp. 466 - 472
Journal Article
Journal Article
Journal Article
Biochimie, ISSN 0300-9084, 12/2014, Volume 107, pp. 95 - 104
pulmonary infection is a leading cause of death in numerous diseases such as cystic fibrosis (CF). The host cytosolic phospholipase A2α (cPLA2α) releases lipid... 
Pseudomonas aeruginosa | IL6 | Inflammation | Cytosolic phospholipase A2α (cPLA2α) | Acute lung infection | Inflammation IL6 | AIRWAY EPITHELIAL-CELLS | LUNG | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Cytosolic phospholipase A2 alpha (cPLA2 alpha) | IL-6 | TRANSMEMBRANE CONDUCTANCE REGULATOR | HOST-DEFENSE | CYSTIC-FIBROSIS | III SECRETION SYSTEM | Group IV Phospholipases A2 - genetics | Lung Diseases - metabolism | Group IV Phospholipases A2 - antagonists & inhibitors | Species Specificity | Lung Diseases - microbiology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Immunoblotting | Male | Pseudomonas Infections - mortality | Pseudomonas aeruginosa - physiology | Extracellular Signal-Regulated MAP Kinases - metabolism | Pseudomonas Infections - metabolism | Group IV Phospholipases A2 - metabolism | Female | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-6 - metabolism | Cell Line | Mice, Inbred CFTR | Macrophages, Alveolar - microbiology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Survival Rate | Arachidonate 15-Lipoxygenase - metabolism | Arachidonic Acids - pharmacology | Mice, Knockout | Pseudomonas Infections - genetics | Host-Pathogen Interactions | Lung Diseases - genetics | Animals | Macrophages, Alveolar - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cyclooxygenase 2 - metabolism | Bronchoalveolar Lavage Fluid - chemistry | Macrophages, Alveolar - metabolism | Pseudomonas aeruginosa - classification
Journal Article