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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2012, Volume 109, Issue 13, pp. 5022 - 5027
Journal Article
International Journal of Obesity, ISSN 0307-0565, 10/2017, Volume 41, Issue 10, pp. 1547 - 1555
Journal Article
Cell and Tissue Research, ISSN 0302-766X, 11/2018, Volume 374, Issue 2, pp. 349 - 365
Ghrelin, a gut-brain peptide hormone, is implicated in a multiplicity of biological functions, including energy homeostasis and reproduction. Neuronal systems... 
Human Genetics | Biomedicine | NPY | Proteomics | Tilapia | Molecular Medicine | IGF-1 | GnRH | BASS DICENTRARCHUS-LABRAX | RAINBOW-TROUT | MESSENGER-RNA EXPRESSION | FOOD-INTAKE | NEUROPEPTIDE-Y | LUTEINIZING-HORMONE | CELL BIOLOGY | FACTOR-LIKE IMMUNOREACTIVITY | IN-VITRO | CENTRAL-NERVOUS-SYSTEM | TROUT ONCORHYNCHUS-MYKISS | Ghrelin - administration & dosage | Growth Hormone - blood | Pituitary Gland - metabolism | Growth Hormone - metabolism | Humans | RNA, Messenger - genetics | Rats | Ghrelin - pharmacology | Growth Hormone-Releasing Hormone - genetics | RNA, Messenger - metabolism | Cichlids - metabolism | Neuropeptide Y - metabolism | Growth Hormone-Releasing Hormone - metabolism | Growth Hormone - genetics | Animals | Hypothalamus - metabolism | Gonadotropin-Releasing Hormone - metabolism | Female | Neurons - metabolism | Hypothalamus - drug effects | Neurons - drug effects | Insulin-Like Growth Factor I - metabolism | Pituitary Gland - drug effects | Brain | Pituitary hormones | RNA | Neurons | Analysis | Fishes | Neuropeptides | Neurophysiology | Neuropeptide Y | Insulin-like growth factor I | Homeostasis | Pituitary (anterior) | Gonadotropins | mRNA | Insulin-like growth factors | Hypothalamus | Insulin | Optical density | Hormone release | Energy balance | Growth hormone-releasing hormone | Ghrelin | Pituitary | Growth hormones | Fish | Gonadotropin-releasing hormone | Growth hormone | Immunofluorescence | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2017, Volume 114, Issue 6, pp. 1359 - 1364
The etiology of benign prostatic hyperplasia (BPH) is multifactorial, and chronic inflammation plays a pivotal role in its pathogenesis. Growth... 
Prostatic hyperplasia | Experimental autoimmune prostatitis | Targeted therapy | Chronic prostatic inflammation | Neuropeptide | targeted therapy | RISK-FACTORS | neuropeptide | MULTIDISCIPLINARY SCIENCES | MESENCHYMAL TRANSITION | experimental autoimmune prostatitis | CANCER | OUTLET OBSTRUCTION | URINARY-TRACT SYMPTOMS | chronic prostatic inflammation | ANDROGEN-RECEPTOR | GENE-EXPRESSION | MOUSE PROSTATE | HYPERPLASIA BPH | T-CELLS | prostatic hyperplasia | Prostatic Hyperplasia - pathology | Epithelial Cells - metabolism | Gene Expression - drug effects | Epithelial Cells - drug effects | Humans | Male | Growth Hormone-Releasing Hormone - pharmacology | Prostatitis - metabolism | Prostate - metabolism | Prostatitis - pathology | Autoimmune Diseases - genetics | Prostate - pathology | Prostate - drug effects | Prostatitis - genetics | Autoimmune Diseases - metabolism | Autoimmune Diseases - pathology | Cell Proliferation - genetics | Cells, Cultured | Rats | Growth Hormone-Releasing Hormone - genetics | Prostatic Hyperplasia - genetics | Prostatic Hyperplasia - metabolism | Transforming Growth Factor beta2 - pharmacology | Growth Hormone-Releasing Hormone - metabolism | Animals | Cell Proliferation - drug effects | Growth Hormone-Releasing Hormone - analogs & derivatives | Mice, Inbred BALB C | Growth Hormone-Releasing Hormone - antagonists & inhibitors | Cytokines | Gene expression | Pathogenesis | Prostate cancer | Rodents | Cells | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2010, Volume 107, Issue 6, pp. 2604 - 2609
Whether the growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis exerts cardioprotective effects remains controversial; and the underlying... 
Heart | Myocardial infarction | Receptors | Stem cells | Placebos | Myocardium | Growth hormones | Mast cells | Hormones | Renovations | Heart failure | Cardiac stem cells | Remodeling | Apoptosis | PROGENITOR CELLS | heart failure | remodeling | MYOCYTES | GHRELIN | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | apoptosis | RECEPTOR | cardiac stem cells | IMPROVES CARDIAC-FUNCTION | FACTOR-I | DILATED CARDIOMYOPATHY | GENE-EXPRESSION | RAT-HEART | Immunohistochemistry | Rats, Inbred F344 | Body Weight - drug effects | Receptors, Neuropeptide - metabolism | Growth Hormone-Releasing Hormone - pharmacology | Myocardial Infarction - pathology | Myocardium - metabolism | Receptors, Pituitary Hormone-Regulating Hormone - metabolism | Female | Heart - physiopathology | Echocardiography | Growth Hormone - blood | Growth Hormone-Releasing Hormone - agonists | Rats | Myocardium - pathology | Growth Hormone - pharmacology | Cardiotonic Agents - pharmacology | Random Allocation | Recombinant Proteins - pharmacology | Blotting, Western | Growth Hormone-Releasing Hormone - metabolism | Growth Hormone - genetics | Organ Size - drug effects | Animals | Heart - drug effects | Growth Hormone-Releasing Hormone - analogs & derivatives | Hemodynamics - drug effects | Myocardial Infarction - prevention & control | Insulin-Like Growth Factor I - metabolism | Somatotropin | Somatotropin releasing hormone | Physiological aspects | Genetic aspects | Gene expression | Properties | Heart attack | Risk factors | Cell growth | Heart attacks | Rodents | T cell receptors | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 6, pp. 2084 - 2089
Aggressive treatment with antibiotics in patients infected with Streptococcus pneumoniae induces release of the bacterial virulence factor pneumolysin (PLY).... 
Pulmonary alveoli | Acute lung injury | Phosphorylation | Lungs | Epithelial cells | Agonists | Hormones | Pretreatment | Pulmonary edema | Endothelial cells | Cyclic AMP | Pneumonia | ACTIVATED PROTEIN-KINASE | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | ACUTE LUNG INJURY | PROLIFERATION | FLUID CLEARANCE | IN-VITRO | STREPTOCOCCUS-PNEUMONIAE | pneumonia | cyclic AMP | VE-CADHERIN | PNEUMOCOCCAL PNEUMONIA | ADHERENS JUNCTIONS | Cadherins - metabolism | Humans | Microvessels - pathology | Receptors, Neuropeptide - metabolism | Streptolysins - toxicity | Antigens, CD - metabolism | Pulmonary Edema - physiopathology | Bacterial Proteins - toxicity | RNA Splicing - genetics | Receptors, Pituitary Hormone-Regulating Hormone - metabolism | Sodium Channels - metabolism | Pulmonary Alveoli - drug effects | Pulmonary Edema - pathology | Lung - metabolism | Receptors, Pituitary Hormone-Regulating Hormone - genetics | Pulmonary Edema - genetics | Lung - pathology | Pulmonary Alveoli - pathology | Growth Hormone-Releasing Hormone - agonists | Endothelial Cells - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Receptors, Neuropeptide - genetics | Permeability | Growth Hormone-Releasing Hormone - genetics | Growth Hormone-Releasing Hormone - metabolism | Animals | Mice | Myosin Light Chains - metabolism | Endothelial Cells - pathology | Ion Channel Gating | Dropsy | Edema | Care and treatment | Somatotropin releasing hormone | Physiological aspects | Research | Health aspects | Pneumococcal infections | Streptococcus pneumoniae | Growth hormones | Polypeptides | Cells | Streptococcus infections | Index Medicus | Biological Sciences
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2016, Volume 36, Issue 4, pp. 663 - 672
OBJECTIVE—The efficiency of cell therapy is limited by poor cell survival and engraftment. Here, we studied the effect of the growth hormone–releasing hormone... 
angiogenesis effects | mesenchymal stromal cells | growth hormone-releasing hormone | SURVIVAL | GHRH RECEPTORS | MYOCARDIAL-INFARCTION | LIMB ISCHEMIA | PROLIFERATION | IN-VITRO | PANCREATIC-ISLETS | PERIPHERAL VASCULAR DISEASE | RAT-HEART | STROMAL CELLS | HEMATOLOGY | EXPRESSION | Hindlimb | Phosphorylation | Antigens, CD34 - metabolism | Apoptosis - drug effects | Male | Peptide Fragments - pharmacology | Receptors, Neuropeptide - metabolism | Growth Hormone-Releasing Hormone - pharmacology | Dose-Response Relationship, Drug | Time Factors | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Receptors, Pituitary Hormone-Regulating Hormone - metabolism | Receptors, Neuropeptide - agonists | Female | Active Transport, Cell Nucleus | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Muscle, Skeletal - blood supply | Cell Survival - drug effects | Mesenchymal Stromal Cells - drug effects | Growth Hormone-Releasing Hormone - agonists | Mice, Inbred C57BL | Cells, Cultured | Ischemia - metabolism | Ischemia - therapy | Mesenchymal Stromal Cells - metabolism | Ischemia - physiopathology | Cell Movement - drug effects | Growth Hormone-Releasing Hormone - metabolism | Animals | Receptors, Pituitary Hormone-Regulating Hormone - agonists | Cell Proliferation - drug effects | Growth Hormone-Releasing Hormone - analogs & derivatives | Mesenchymal Stem Cell Transplantation | Neovascularization, Physiologic | Index Medicus | limb ischemia | agonist | Growth hormone-releasing hormone | mesenchymal stem cells | angiogenesis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 9, pp. 3755 - 3760
Growth hormone-releasing hormone (GHRH), a hypothalamic polypeptide, acts as a potent autocrine/paracrine growth factor in many cancers. Benign prostatic... 
Hormone antagonists | Receptors | Cell growth | Cytokines | Epithelial cells | Genes | Prostatic hyperplasia | Hormones | Prostate | Apoptosis | Rodent benign prostatic hyperplasia model | Prostatic hypertrophy | Chronic prostatic inflammation | Prostatic cell death | CYCLOOXYGENASE-2 | MULTIDISCIPLINARY SCIENCES | prostatic cell death | PROLIFERATION | rodent benign prostatic hyperplasia model | COMBINATION | SPLICE VARIANTS | CANCER | INHIBITION | THERAPY | prostatic hypertrophy | CELL LUNG-CARCINOMA | INFLAMMATION | chronic prostatic inflammation | EXPRESSION | Immunohistochemistry | Transcription, Genetic - drug effects | Prostatic Hyperplasia - pathology | Sermorelin - administration & dosage | Apoptosis - drug effects | Humans | Receptors, Androgen - metabolism | Male | NF-kappa B - metabolism | Receptors, Neuropeptide - metabolism | Prostate - metabolism | Inflammation - complications | Prostate - pathology | Interleukin-1beta - metabolism | Receptors, Pituitary Hormone-Regulating Hormone - metabolism | Inflammation Mediators - metabolism | Sermorelin - pharmacology | Prostate - drug effects | Sermorelin - analogs & derivatives | Gene Expression Regulation, Neoplastic - drug effects | Receptors, Pituitary Hormone-Regulating Hormone - genetics | Rats | Receptors, Neuropeptide - genetics | Signal Transduction - genetics | Down-Regulation - drug effects | Growth Hormone-Releasing Hormone - genetics | Prostatic Hyperplasia - genetics | Cell Division - drug effects | Prostate-Specific Antigen - blood | Growth Hormone-Releasing Hormone - metabolism | Organ Size - drug effects | Alternative Splicing - drug effects | Animals | Signal Transduction - drug effects | Cyclooxygenase 2 - metabolism | Inflammation - genetics | Prostatic Hyperplasia - blood | Prostatic Hyperplasia - enzymology | Growth Hormone-Releasing Hormone - antagonists & inhibitors | Insulin-Like Growth Factor I - metabolism | Genetic aspects | Polypeptides | Somatotropin releasing hormone | Health aspects | Hypertrophy | Signal transduction | Tissue | Pathogenesis | Growth hormones | Effects | Prostate cancer | Tumors | Index Medicus | Biological Sciences
Journal Article
International Journal of Cancer, ISSN 0020-7136, 06/2018, Volume 142, Issue 11, pp. 2394 - 2404
We investigated the effects of novel antagonists of growth hormone releasing hormone (GHRH)—MIA602 and MIA690—on three human small cell lung cancer (SCLC)... 
SCLC | GHRH receptors | signaling pathways | NSCLC | GHRH antagonists | RECEPTOR | PROLIFERATION | SUPPRESSION | BOMBESIN | ONCOLOGY | GHRH | IN-VIVO | PROSTATE-CANCER | TUMOR-GROWTH | CARCINOMA | EXPRESSION | Apoptosis - drug effects | Humans | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | Sermorelin - pharmacology | Sermorelin - analogs & derivatives | Female | Antineoplastic Agents - pharmacology | Cyclic AMP - metabolism | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Cell Survival - drug effects | Gene Expression | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Small Cell Lung Carcinoma - genetics | Growth Hormone-Releasing Hormone - genetics | Xenograft Model Antitumor Assays | Growth Hormone-Releasing Hormone - metabolism | Animals | Signal Transduction - drug effects | Mice, Nude | Cyclic AMP Response Element-Binding Protein - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Cell Cycle - drug effects | Growth Hormone-Releasing Hormone - antagonists & inhibitors | Cell Movement | Somatotropin | Somatotropin releasing hormone | Lung cancer, Non-small cell | Analysis | Protein binding | Phosphorylation | Animal models | Transcription | Lung | Lung cancer | Cyclic AMP | Antagonists | Kinases | E-cadherin | Cell adhesion & migration | Signaling | Growth hormone-releasing hormone | Pituitary | Animal tissues | Cyclin-dependent kinase inhibitor p27 | Growth hormones | Inhibition | Growth hormone | Viability | Cell migration | Tumors | Cancer | Apoptosis | Index Medicus
Journal Article