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1. Full Text Synthesis and biological activity of pyrrole analogues of combretastatin A-4
by Jung, Eun-Kyung and Leung, Euphemia and Barker, David
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 07/2016, Volume 26, Issue 13, pp. 3001 - 3005
A series of pyrrole analogues of combretastatin (CA-4) were synthesized and tested for their anti-proliferative activity. The highly diastereoselective... 
Acyl-Claisen | Combretastatin A-4 | Antiproliferative agents | Pyrroles | Cancer | DESIGN | CHEMISTRY, MEDICINAL | BRIDGED ANALOGS | ANTICANCER AGENTS | RING | CHEMISTRY, ORGANIC | HYBRIDS | Antineoplastic Agents - chemical synthesis | Humans | Stilbenes - chemical synthesis | Guaiacol - pharmacology | Stilbenes - chemistry | Structure-Activity Relationship | Stilbenes - pharmacology | Antineoplastic Agents - chemistry | Pyrroles - pharmacology | Pyrroles - chemical synthesis | Guaiacol - analogs & derivatives | Guaiacol - chemical synthesis | Cell Line, Tumor | Guaiacol - chemistry | Inhibitory Concentration 50 | Pyrroles - chemistry | Antineoplastic Agents - pharmacology | Drug Screening Assays, Antitumor | Antimitotic agents | Antineoplastic agents | Thiophene
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2. Full Text Pharmacokinetics of Paradol Analogues Orally Administered to Rats
by Setoguchi, Shuichi and Watase, Daisuke and Nagata-Akaho, Nami and Haratake, Akinori and Matsunaga, Kazuhisa and Takata, Jiro
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 03/2016, Volume 64, Issue 9, pp. 1932 - 1937
The kinetics parameters of paradols with different acyl chain lengths have been evaluated to determine their antiobesity site of action. Rats were orally... 
pharmacokinetics | metabolite | acyl chain length | parent compound | paradol analogue | FOOD SCIENCE & TECHNOLOGY | INCREASES | BROWN ADIPOSE-TISSUE | BODY ENERGY-EXPENDITURE | GRAINS | METABOLISM | INGESTION | AGRICULTURE, MULTIDISCIPLINARY | FAT | AFRAMOMUM-MELEGUETA | CHEMISTRY, APPLIED | EXTRACT | CAPSAICIN | Anti-Obesity Agents - administration & dosage | Guaiacol - pharmacokinetics | Rats | Catechols | Male | Rats, Sprague-Dawley | Animals | Phenols - pharmacokinetics | Ketones - blood | Ketones - pharmacokinetics | Guaiacol - analogs & derivatives | Guaiacol - blood | Ketones - chemistry | Guaiacol - chemistry | Phenols - chemistry | Fatty Alcohols
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3. Full Text Synthesis and antiproliferative activities of quebecol and its analogs
by Pericherla, Kasiviswanadharaju and Shirazi, Amir Nasrolahi and Kameshwara Rao, V and Tiwari, Rakesh K and DaSilva, Nicholas and McCaffrey, Kellen T and Beni, Yousef A and González-Sarrías, Antonio and Seeram, Navindra P and Parang, Keykavous and Kumar, Anil
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2013, Volume 23, Issue 19, pp. 5329 - 5331
Total synthesis of quebecol and its derivatives and evaluation of their antiproliferative activities are reported. Simple and efficient synthesis of quebecol... 
Antiproliferative | Phenolic | Quebecol | Synthesis | Structure–activity relationship | Structure-activity relationship | CHEMISTRY, MEDICINAL | MAPLE SYRUP | CHEMISTRY, ORGANIC | Cell Survival - drug effects | Antineoplastic Agents - chemical synthesis | Humans | Guaiacol - pharmacology | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Propanols - pharmacology | Propanols - chemical synthesis | Neoplasms - drug therapy | Propanols - chemistry | Guaiacol - analogs & derivatives | Guaiacol - chemical synthesis | Cell Line, Tumor | Guaiacol - chemistry | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | HeLa Cells
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4. Full Text Relationship between the Acyl Chain Length of Paradol Analogues and Their Antiobesity Activity following Oral Ingestion
by Haratake, Akinori and Watase, Daisuke and Setoguchi, Shuichi and Terada, Kazuki and Matsunaga, Kazuhisa and Takata, Jiro
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 07/2014, Volume 62, Issue 26, pp. 6166 - 6174
6-Paradol is known to activate thermogenesis in brown adipose tissue (BAT), and paradol analogues with different acyl chain lengths possess different pungency... 
antiobesity activity | acyl chain | oral ingestion | paradol analogue | uncoupling protein | CAPSAICIN ANALOG | HIGH-FAT DIET | FOOD SCIENCE & TECHNOLOGY | PUNGENT PRINCIPLE | BROWN ADIPOSE-TISSUE | CATECHOLAMINE SECRETION | SKELETAL-MUSCLE | ADAPTIVE THERMOGENESIS | AGRICULTURE, MULTIDISCIPLINARY | UNCOUPLING PROTEIN-3 | NERVOUS-SYSTEM ACTIVITY | CHEMISTRY, APPLIED | CAPSICUM FRUITS | Lipolysis - drug effects | Guaiacol - administration & dosage | Guaiacol - pharmacology | Male | Structure-Activity Relationship | Mitochondrial Proteins - agonists | Anti-Obesity Agents - therapeutic use | Guaiacol - therapeutic use | Mitochondrial Proteins - metabolism | Guaiacol - analogs & derivatives | Guaiacol - chemistry | Ketones - therapeutic use | Ketones - pharmacology | Anti-Obesity Agents - administration & dosage | Administration, Oral | Mice, Inbred C57BL | Cells, Cultured | Ketones - administration & dosage | Random Allocation | Rats, Sprague-Dawley | Adipose Tissue, Brown - pathology | Obesity - metabolism | Obesity - pathology | Up-Regulation - drug effects | Anti-Obesity Agents - chemistry | Animals | Ion Channels - metabolism | Obesity - prevention & control | Ketones - chemistry | Ion Channels - agonists | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Uncoupling Protein 1 | Anti-Obesity Agents - pharmacology
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5. Full Text Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro
by NATHWANI, SEEMA-MARIA and HUGHES, LINDA and GREENE, LISA M and CARR, MIRIAM and O'BOYLE, NIAMH M and McDONNELL, SUSAN and MEEGAN, MARY J and ZISTERER, DANIELA M
Oncology Reports, ISSN 1021-335X, 2/2013, Volume 29, Issue 2, pp. 585 - 594
Combretastatin A-4 (CA-4) is a naturally occurring microtubular-destabilising agent that possesses potent anti-tumour and anti-vascular properties both in... 
microtubule-targeting agents | endothelial cells | combretastatin A-4 | metastasis | anti-vascular | Anti-vascular | Microtubule-targeting agents | Combretastatin A-4 | Metastasis | Endothelial cells | TARGETING AGENT COMBRETASTATIN-A4 | CANCER-CELLS | MITOTIC CATASTROPHE | ANTINEOPLASTIC AGENTS | HUMAN-ENDOTHELIAL-CELLS | MICROTUBULE DYNAMICS | ANTITUMOR-ACTIVITY | TUMOR VASCULATURE | ONCOLOGY | GROWTH-FACTOR | A4 PHOSPHATE | Cell Survival - drug effects | Human Umbilical Vein Endothelial Cells - drug effects | Apoptosis - drug effects | Humans | Guaiacol - pharmacology | Vascular Endothelial Growth Factor A - metabolism | Azetidines - pharmacology | Breast Neoplasms - metabolism | Cell Movement - drug effects | beta-Lactams - pharmacology | Adenocarcinoma - metabolism | G2 Phase Cell Cycle Checkpoints - drug effects | Cell Differentiation - drug effects | Microtubules - drug effects | Guaiacol - analogs & derivatives | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Studies | Breast cancer | Kinases | Apoptosis | Cell adhesion & migration | Index Medicus
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6. Full Text Microwave-assisted deuterium exchange: The convenient preparation of isotopically labelled analogues for stable isotope dilution analysis of volatile wine phenols
by Crump, Anna M and Sefton, Mark A and Wilkinson, Kerry L
Food Chemistry, ISSN 0308-8146, 11/2014, Volume 162, pp. 261 - 263
This study reports the convenient, low cost, one-step synthesis of labelled analogues of six volatile phenols, guaiacol, 4-methylguaiacol, 4-ethylguaiacol,... 
Isotope labelling | Volatile phenols | Microwave-assisted deuterium exchange | NUTRITION & DIETETICS | GUAIACOL | FOOD SCIENCE & TECHNOLOGY | SMOKE | RED WINE | CHEMISTRY, APPLIED | ODOR | Deuterium | Reproducibility of Results | Volatile Organic Compounds - analysis | Benzaldehydes | Eugenol | Wine - analysis | Isotope Labeling - methods | Phenols - analysis | Cresols | Guaiacol - analogs & derivatives | Indicator Dilution Techniques | Mass Spectrometry - methods | Microwaves | Phenols
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7. Full Text Synthesis, biological evaluation, and docking studies of gigantol analogs as calmodulin inhibitors
by Reyes-Ramírez, Adelfo and Leyte-Lugo, Martha and Figueroa, Mario and Serrano-Alba, Trinidad and González-Andrade, Martín and Mata, Rachel
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2011, Volume 46, Issue 7, pp. 2699 - 2708
Several analogs of gigantol ( ) were synthesized to evaluate their effect on the complexes Ca –calmodulin (CaM) and Ca –CaM–CaM sensitive phosphodiesterase 1... 
1,3-Diphenylpropenones | Gigantol | 1,2-Diphenylethanes | Calmodulin | 1,3-Diphenylpropanes | SCAPHYGLOTTIS-LIVIDA | CHEMISTRY, MEDICINAL | STILBENOIDS | DERIVATIVES | Cyclic Nucleotide Phosphodiesterases, Type 1 - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Bibenzyls - chemistry | Antipsychotic Agents - chemical synthesis | Cyclic Nucleotide Phosphodiesterases, Type 1 - antagonists & inhibitors | Antidepressive Agents - chemistry | Guaiacol - analogs & derivatives | Guaiacol - chemical synthesis | Parasympatholytics - chemical synthesis | Guaiacol - chemistry | Biphenyl Compounds - chemistry | Calmodulin - chemistry | Parasympatholytics - chemistry | Anesthetics, Local - chemistry | Chlorpromazine - chemistry | Trifluoperazine - chemistry | Antineoplastic Agents - chemistry | Bibenzyls - chemical synthesis | Antipsychotic Agents - chemistry | Biphenyl Compounds - chemical synthesis | Biosensing Techniques | Antidepressive Agents - chemical synthesis | Protein Binding | Molecular Docking Simulation | Anesthetics, Local - chemical synthesis | Calmodulin - antagonists & inhibitors
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8. Full Text Hydrodeoxygenation of phenolics in liquid phase over supported MoO3 and carburized analogues
by Lødeng, Rune and Ranga, Chanakya and Rajkhowa, Tapas and Alexiadis, Vaios I and Bjørkan, Hilde and Chytil, Svatopluk and Svenum, Ingeborg H and Walmsley, John and Thybaut, Joris W
Biomass Conversion and Biorefinery, ISSN 2190-6815, 9/2017, Volume 7, Issue 3, pp. 343 - 359
Catalytic hydrodeoxygenation (HDO) of mono-aromatic components of increasing structural and chemical complexity, represented by phenol (−OH), anisole (−OCH3),... 
Engineering | Biotechnology | Phenol | Guaiacol | Hydrodeoxygenation | Anisole | Renewable and Green Energy | Bio-oil | Molybdenum oxide | Catalysis | Kinetics | FAST PYROLYSIS OIL | ENERGY & FUELS | PHOSPHIDE HYDROPROCESSING CATALYSTS | HYDRODESULFURIZATION | MODEL COMPOUNDS | ENGINEERING, CHEMICAL | BIOMASS | TRANSITION-METAL PHOSPHIDES | HYDROTREATING CATALYSTS | Molybdenumoxide | NITRIDES | MOLYBDENUM OXIDE
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9. Full Text DM-1, sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phenolate: a curcumin analog with a synergic effect in combination with paclitaxel in breast cancer treatment
by Faião-Flores, Fernanda and Suarez, José Agustín Quincoces and Pardi, Paulo Celso and Maria, Durvanei Augusto
Tumor Biology, ISSN 1010-4283, 6/2012, Volume 33, Issue 3, pp. 775 - 785
This paper describes a new method for the preparation of sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phenolate, DM-1, and... 
Adjuvant antitumor therapy | Biomedicine | Phenolate DM-1 | Paclitaxel | Cancer Research | Metastatic breast cancer | Curcumin analog | Apoptosis | PhenolateDM-1 | TUMOR PROGRESSION | VIVO | PANCREATIC-CANCER | FACTOR-KAPPA-B | PROLIFERATION | CELL-GROWTH | ANTICANCER ACTIVITY | ONCOLOGY | GENE-PRODUCTS | Adjuvantantitumor therapy | GROWTH IN-VITRO | AGENTS | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Apoptosis - drug effects | Guaiacol - administration & dosage | Caspase 3 - metabolism | Guaiacol - pharmacology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Neoplasm Metastasis | Guaiacol - therapeutic use | Guaiacol - analogs & derivatives | Mammary Neoplasms, Experimental - pathology | Female | Ketones - therapeutic use | Paclitaxel - administration & dosage | Mammary Neoplasms, Experimental - drug therapy | Ketones - pharmacology | Mammary Neoplasms, Experimental - mortality | Ketones - administration & dosage | Adenocarcinoma - drug therapy | Animals | Tumor Burden - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Adenocarcinoma - mortality | Care and treatment | Adjuvant treatment | Breast cancer | Metastasis | Antineoplastic agents | Antimitotic agents | Chemotherapy | Analysis | Universities and colleges | Drug therapy | Tumors | Cancer | Rodents
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10. Full Text The synthesis and tubulin binding activity of thiophene-based analogues of combretastatin A-4
by Flynn, Bernard L and Flynn, Guy P and Hamel, Ernest and Jung, M.Katherine
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2001, Volume 11, Issue 17, pp. 2341 - 2343
A number of analogues of combretastatin A-4 (1), containing a thiophene ring interposed between the two phenyl groups, have been prepared. The synthesis of... 
HALOCYCLIZATION REACTIONS | PHOSPHATE | UNSATURATED SULFIDES | CELLS | POTENT | CHEMISTRY, MEDICINAL | COLCHICINE SITE | PRODRUG | ANTIMITOTIC NATURAL-PRODUCTS | ANTINEOPLASTIC AGENTS | CHEMISTRY, ORGANIC | Colchicine - pharmacology | Guaiacol - metabolism | Humans | Colchicine - metabolism | Guaiacol - pharmacology | Thiophenes - pharmacology | Thiophenes - metabolism | Stilbenes - chemistry | Structure-Activity Relationship | Stilbenes - pharmacology | Antineoplastic Agents - chemistry | Breast Neoplasms - drug therapy | Tubulin - drug effects | Antineoplastic Agents - metabolism | Tubulin - metabolism | Guaiacol - analogs & derivatives | Guaiacol - chemistry | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Thiophenes - chemistry | Drug Screening Assays, Antitumor
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11. Full Text Curcumin analogue identified as hyaluronan export inhibitor by virtual docking to the ABC transporter MRP5
by Prehm, Peter
Food and Chemical Toxicology, ISSN 0278-6915, 12/2013, Volume 62, pp. 76 - 81
Hyaluronan is overproduced in many diseases including metastasis, inflammation or ischemia, but there is no drug to attenuate hyaluronan production. Hyaluronan... 
Hyaluronan export inhibitor | Extracellular matrix | Virtual docking | MRP5 | Plasma membrane | CARCINOMA-CELLS | PLASMA-MEMBRANES | GROWTH SUPPRESSIVE ACTIVITY | CANCER CELLS | FOOD SCIENCE & TECHNOLOGY | DRUG DISCOVERY | DIFFERENTIATED TERATOCARCINOMA CELLS | HOPS HUMULUS-LUPULUS | ARTICULAR CHONDROCYTES | HUMAN FIBROBLASTS | TOXICOLOGY | NF-KAPPA-B | Ketones - pharmacology | Protein Structure, Tertiary | Guaiacol - metabolism | Curcumin - analogs & derivatives | Humans | Propiophenones - pharmacology | Multidrug Resistance-Associated Proteins - chemistry | Guaiacol - pharmacology | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | HEK293 Cells - drug effects | Guaiacol - analogs & derivatives | Hyaluronic Acid - metabolism | Inhibitory Concentration 50 | Protein Conformation | Biological Transport - drug effects | Flavonoids - pharmacology | Molecular Docking Simulation | Binding Sites | Ketones - metabolism | Multidrug Resistance-Associated Proteins - metabolism | Hyaluronic acid | International trade | Index Medicus
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12. Full Text Synthesis of a New [6]-Gingerol Analogue and Its Protective Effect with Respect to the Development of Metabolic Syndrome in Mice Fed a High-Fat Diet
by Okamoto, Mayumi and Irii, Hiroyuki and Tahara, Yu and Ishii, Hiroyuki and Hirao, Akiko and Udagawa, Haruhide and Hiramoto, Masaki and Yasuda, Kazuki and Takanishi, Atsuo and Shibata, Shigenobu and Shimizu, Isao
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2011, Volume 54, Issue 18, pp. 6295 - 6304
To determine the effects of a [6]-gingerol analogue (6G), a major chemical component of the ginger rhizome, and its stable analogue after digestion in... 
GINGER ZINGIBER-OFFICINALE | OBESITY | CHEMISTRY, MEDICINAL | PUNGENT | RATS | CHEMISTRY | RESONANCE SPECTROSCOPY | QUALITY EVALUATION | INSULIN SENSITIVITY | TECHNOLOGY | EXPRESSION | Metabolic Syndrome - etiology | Catechols - chemical synthesis | Amides - chemical synthesis | Fatty Alcohols - chemical synthesis | Leptin - metabolism | Body Weight - drug effects | Guaiacol - pharmacology | Catechols - chemistry | Male | Metabolic Syndrome - metabolism | Fatty Alcohols - chemistry | RNA, Messenger - metabolism | Acetyl-CoA Carboxylase - genetics | Fatty Alcohols - pharmacology | Adipose Tissue - metabolism | Liver - drug effects | Adiponectin - genetics | Guaiacol - analogs & derivatives | Dietary Fats - administration & dosage | Guaiacol - chemical synthesis | Catechols - pharmacology | Guaiacol - chemistry | Adiponectin - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Amides - pharmacology | Glucose Tolerance Test | Blood Glucose - analysis | Liver - metabolism | Adipose Tissue - pathology | Leptin - genetics | Mice, Inbred ICR | Anti-Obesity Agents - chemistry | Insulin - metabolism | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Anti-Obesity Agents - chemical synthesis | Lipogenesis - drug effects | Amides - chemistry | Metabolic Syndrome - prevention & control | Mice | Adipose Tissue - drug effects | Anti-Obesity Agents - pharmacology | Acetyl-CoA Carboxylase - metabolism | Energy Metabolism - drug effects
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13. Full Text Structural Analogues of Homoeriodictyol as Flavor Modifiers. Part III: Short Chain Gingerdione Derivatives
by Ley, Jakob P and Paetz, Susanne and Blings, Maria and Hoffmann-Lücke, Petra and Bertram, Heinz-Jürgen and Krammer, Gerhard E
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 08/2008, Volume 56, Issue 15, pp. 6656 - 6664
In order to find new flavor modifiers, various short chain gingerdione derivatives were synthesized as structural analogues of the known bitter masker... 
Flavors and Aromas/Chemosensory Perception | Bitter masking | Sweet enhancing | Gingerdiones | Taste modifying | TASTE DILUTION ANALYSIS | gingerdiones | SWEETNESS | FOOD SCIENCE & TECHNOLOGY | taste modifying | PGE PRODUCTION | BITTER TASTE | REDUCTION | sweet enhancing | AGRICULTURE, MULTIDISCIPLINARY | bitter masking | CHEMISTRY, APPLIED | ZINGIBER-OFFICINALE | Carbohydrates | Flavoring Agents - pharmacology | Guaiacol - pharmacology | Structure-Activity Relationship | Flavones - chemistry | Quinine | Benzyl Alcohols | Taste - drug effects | Guaiacol - analogs & derivatives | Flavoring Agents - chemistry | Guaiacol - chemistry | Caffeine | Glucosides
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14. Full Text 4-Fluoro-2-methoxyphenol, an apocynin analog with enhanced inhibitory effect on leukocyte oxidant production and phagocytosis
by de Almeida, Ana Carolina and Marques, Otávio Cabral and Arslanian, Christina and Condino-Neto, Antonio and Ximenes, Valdecir F
European Journal of Pharmacology, ISSN 0014-2999, 06/2011, Volume 660, Issue 2-3, pp. 445 - 453
Apocynin, a methoxy-substituted catechol (4-hydroxy-3-methoxyacetophenone), originally extracted from the roots of , has been extensively used as a non-toxic... 
Myeloperoxidase | TNFα | Neutrophil | Apocynin | NADPH oxidase | Phagocytosis | DRUG | CELLS | TNF alpha | ATHEROSCLEROSIS | NEUTROPHILS | METHOXY-SUBSTITUTED CATECHOL | WHOLE-BLOOD | PHARMACOLOGY & PHARMACY | FLOW-CYTOMETRY | HYPERTENSION | Guaiacol - metabolism | Leukocytes, Mononuclear - metabolism | Reactive Oxygen Species - metabolism | Leukocytes, Mononuclear - secretion | Staphylococcus aureus - physiology | Humans | Guaiacol - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Leukocytes - immunology | Guaiacol - analogs & derivatives | Leukocytes - microbiology | Acetophenones - pharmacology | Neutrophils - secretion | Superoxides - metabolism | Guaiacol - chemistry | Guaiacol - toxicity | Candida albicans - physiology | Cell Membrane - metabolism | Acetophenones - toxicity | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Acetophenones - metabolism | Neutrophils - metabolism | Cell Membrane - drug effects | Phagocytosis - drug effects | Leukocytes, Mononuclear - drug effects | Neutrophils - drug effects | Tumor Necrosis Factor-alpha - secretion | Anti-Inflammatory Agents, Non-Steroidal - toxicity | Acetophenones - chemistry | Hydrophobic and Hydrophilic Interactions | Leukocytes - drug effects | Oxidants - biosynthesis | Leukocytes - metabolism | Hypochlorous Acid - metabolism | Peroxidase - metabolism | Oxidases | Catechin | Catechol | Index Medicus
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15. Full Text 3-(3-Hydroxy-4-methoxyphenyl)-4-(3,4,5-trimethoxyphenyl)-1,2,5-selenadiazole (G-1103), a novel combretastatin A-4 analog, induces G2/M arrest and apoptosis by disrupting tubulin polymerization in human cervical HeLa cells and fibrosarcoma HT-1080 cells
by Zuo, Daiying and Guo, Dandan and Jiang, Xuewei and Guan, Qi and Qi, Huan and Xu, Jingwen and Li, Zengqiang and Yang, Fushan and Zhang, Weige and Wu, Yingliang
Chemico-Biological Interactions, ISSN 0009-2797, 02/2015, Volume 227, pp. 7 - 17
Microtubule is a popular target for anticancer drugs. In this study, we describe the effect... 
G-1103 | HT-1080 | HeLa | Combretastatin A-4 | G2/M arrest | Apoptosis | Bibenzyls - toxicity | Caspase 9 - metabolism | Organoselenium Compounds - chemical synthesis | Apoptosis - drug effects | Humans | Caspase 8 - metabolism | Uterine Cervical Neoplasms - pathology | Cyclin B1 - metabolism | Fibrosarcoma - metabolism | Bibenzyls - chemistry | Organoselenium Compounds - chemistry | Proto-Oncogene Proteins c-bcl-2 - metabolism | Microtubules - metabolism | Fibrosarcoma - pathology | G2 Phase Cell Cycle Checkpoints - drug effects | Uterine Cervical Neoplasms - metabolism | Guaiacol - analogs & derivatives | Guaiacol - chemical synthesis | Guaiacol - chemistry | Guaiacol - toxicity | Female | cdc25 Phosphatases - metabolism | M Phase Cell Cycle Checkpoints - drug effects | bcl-2-Associated X Protein - metabolism | Down-Regulation - drug effects | Organoselenium Compounds - toxicity | Up-Regulation - drug effects | Cell Line, Tumor | HeLa Cells
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16. Full Text XH-14 analogues as adenosine antagonists
by Scammells, Peter J and Baker, Stephen P and Beauglehole, Anthony R
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 09/1998, Volume 6, Issue 9, pp. 1517 - 1524
Analogues of the potent adenosine antagonist 5-(3'-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzo[b]furan-3-carbaldehyde (XH-14, 1) with... 
benzofuran | A1 adenosine receptor | Adenosine antagonist | adenosine receptor | Benzofuran | HALIDES | FORMYLATION | CHEMISTRY, MEDICINAL | CARBON-MONOXIDE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | A adenosine receptor | RECEPTORS | adenosine antagonist | Benzofurans - chemistry | Cell Line | Purinergic P1 Receptor Antagonists | Magnetic Resonance Spectroscopy | Guaiacol - analogs & derivatives | Adenosine - metabolism | Benzofurans - pharmacology | Structure-Activity Relationship | Receptors, Purinergic P1 - metabolism | Adenosine - antagonists & inhibitors
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17. Full Text Evaluation of aroma differences between high-salt liquid-state fermentation and low-salt solid-state fermentation soy sauces from China
by Feng, Yunzi and Cai, Yu and Su, Guowan and Zhao, Mouming and Zhao, Haifeng and Wang, Chenxia
Food Chemistry, ISSN 0308-8146, 02/2014, Volume 145, pp. 126 - 134
Two types of Chinese soy sauce, high-salt liquid-state fermentation soy sauce (HLFSS) and low-salt solid-state fermentation soy sauce (LSFSS), were used to... 
Aroma extract dilution analysis | Key aroma-active compounds | SPME–GC-O | Chinese soy sauces | SPME-GC-O | ODORANTS | NUTRITION & DIETETICS | FOOD SCIENCE & TECHNOLOGY | COMPONENTS | PHASE MICROEXTRACTION | VOLATILE COMPOUNDS | CHEMISTRY, APPLIED | GAS CHROMATOGRAPHY-OLFACTOMETRY | Sodium Chloride - analysis | Gas Chromatography-Mass Spectrometry | Solid Phase Microextraction | Humans | Male | Fermentation | Soy Foods - analysis | Odorants - analysis | Smell | Young Adult | Food Analysis | Aldehydes - analysis | China | Guaiacol - analogs & derivatives | Ethanol - analysis | Vinyl Compounds - analysis | Acetaldehyde - analysis | Adult | Female | Pentanols - analysis | Taste | Acetaldehyde - analogs & derivatives | Guaiacol - analysis
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