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1. Full Text Synthesis and biological activity of pyrrole analogues of combretastatin A-4
by Jung, Eun-Kyung and Leung, Euphemia and Barker, David
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 07/2016, Volume 26, Issue 13, pp. 3001 - 3005
Acyl-Claisen | Combretastatin A-4 | Antiproliferative agents | Pyrroles | Cancer | Antineoplastic Agents - chemical synthesis | Humans | Stilbenes - chemical synthesis | Guaiacol - pharmacology | Stilbenes - chemistry | Structure-Activity Relationship | Stilbenes - pharmacology | Antineoplastic Agents - chemistry | Pyrroles - pharmacology | Pyrroles - chemical synthesis | Guaiacol - analogs & derivatives | Guaiacol - chemical synthesis | Cell Line, Tumor | Guaiacol - chemistry | Inhibitory Concentration 50 | Pyrroles - chemistry | Antineoplastic Agents - pharmacology | Drug Screening Assays, Antitumor | Antimitotic agents | Antineoplastic agents | Thiophene | Index Medicus
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2. Full Text Pharmacokinetics of Paradol Analogues Orally Administered to Rats
by Setoguchi, Shuichi and Watase, Daisuke and Nagata-Akaho, Nami and Haratake, Akinori and Matsunaga, Kazuhisa and Takata, Jiro
Journal of agricultural and food chemistry, ISSN 0021-8561, 03/2016, Volume 64, Issue 9, pp. 1932 - 1937
pharmacokinetics | metabolite | acyl chain length | parent compound | paradol analogue | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Food Science & Technology | Agriculture, Multidisciplinary | Agriculture | Science & Technology | Anti-Obesity Agents - administration & dosage | Guaiacol - pharmacokinetics | Rats | Catechols | Male | Rats, Sprague-Dawley | Animals | Phenols - pharmacokinetics | Ketones - blood | Ketones - pharmacokinetics | Guaiacol - analogs & derivatives | Guaiacol - blood | Ketones - chemistry | Guaiacol - chemistry | Phenols - chemistry | Fatty Alcohols | Index Medicus
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3. Full Text Chemoenzymatic Total Synthesis of Sorbicatechol Structural Analogues and Evaluation of Their Antiviral Potential
by Sib, Anna and Milzarek, Tobias M and Herrmann, Alexander and Oubraham, Lila and Müller, Jonas I and Pichlmair, Andreas and Brack‐Werner, Ruth and Gulder, Tobias A. M
Chembiochem : a European journal of chemical biology, ISSN 1439-4227, 02/2020, Volume 21, Issue 4, pp. 492 - 495
sorbicillinoids | natural products | total synthesis | antiviral agents | biocatalysis | Polyketides | Molecular structure | Natural products | Oxidoreductase | Antiviral activity | Viruses | Alkanes | Ethers | Oxygenation | Index Medicus | Communications | Communication
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4. Full Text Synthesis and antiproliferative activities of quebecol and its analogs
by Pericherla, Kasiviswanadharaju and Shirazi, Amir Nasrolahi and Kameshwara Rao, V and Tiwari, Rakesh K and DaSilva, Nicholas and McCaffrey, Kellen T and Beni, Yousef A and González-Sarrías, Antonio and Seeram, Navindra P and Parang, Keykavous and Kumar, Anil
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 10/2013, Volume 23, Issue 19, pp. 5329 - 5331
Antiproliferative | Phenolic | Quebecol | Synthesis | Structure–activity relationship | Structure-activity relationship | Cell Survival - drug effects | Antineoplastic Agents - chemical synthesis | Humans | Guaiacol - pharmacology | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Propanols - pharmacology | Propanols - chemical synthesis | Neoplasms - drug therapy | Propanols - chemistry | Guaiacol - analogs & derivatives | Guaiacol - chemical synthesis | Cell Line, Tumor | Guaiacol - chemistry | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | HeLa Cells | Index Medicus
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5. Full Text Relationship between the Acyl Chain Length of Paradol Analogues and Their Antiobesity Activity following Oral Ingestion
by Haratake, Akinori and Watase, Daisuke and Setoguchi, Shuichi and Terada, Kazuki and Matsunaga, Kazuhisa and Takata, Jiro
Journal of agricultural and food chemistry, ISSN 0021-8561, 07/2014, Volume 62, Issue 26, pp. 6166 - 6174
antiobesity activity | acyl chain | oral ingestion | paradol analogue | uncoupling protein | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Food Science & Technology | Agriculture, Multidisciplinary | Agriculture | Science & Technology | Lipolysis - drug effects | Guaiacol - administration & dosage | Guaiacol - pharmacology | Male | Structure-Activity Relationship | Mitochondrial Proteins - agonists | Anti-Obesity Agents - therapeutic use | Guaiacol - therapeutic use | Mitochondrial Proteins - metabolism | Guaiacol - analogs & derivatives | Guaiacol - chemistry | Ketones - therapeutic use | Ketones - pharmacology | Anti-Obesity Agents - administration & dosage | Administration, Oral | Mice, Inbred C57BL | Cells, Cultured | Ketones - administration & dosage | Random Allocation | Rats, Sprague-Dawley | Adipose Tissue, Brown - pathology | Obesity - metabolism | Obesity - pathology | Up-Regulation - drug effects | Anti-Obesity Agents - chemistry | Animals | Ion Channels - metabolism | Obesity - prevention & control | Ketones - chemistry | Ion Channels - agonists | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Uncoupling Protein 1 | Anti-Obesity Agents - pharmacology | Index Medicus
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6. Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro
by Nathwani, Seema-Maria and Hughes, Linda and Greene, Lisa M and Carr, Miriam and O'Boyle, Niamh M and McDonnell, Susan and Meegan, Mary J and Zisterer, Daniela M
Oncology reports, ISSN 1021-335X, 02/2013, Volume 29, Issue 2, pp. 585 - 594
Anti-vascular | Microtubule-targeting agents | Combretastatin A-4 | Metastasis | Endothelial cells | Life Sciences & Biomedicine | Oncology | Science & Technology | Cell Survival - drug effects | Human Umbilical Vein Endothelial Cells - drug effects | Apoptosis - drug effects | Humans | Guaiacol - pharmacology | Vascular Endothelial Growth Factor A - metabolism | Azetidines - pharmacology | Breast Neoplasms - metabolism | Cell Movement - drug effects | beta-Lactams - pharmacology | Adenocarcinoma - metabolism | G2 Phase Cell Cycle Checkpoints - drug effects | Cell Differentiation - drug effects | Microtubules - drug effects | Guaiacol - analogs & derivatives | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Index Medicus
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7. Full Text Microwave-assisted deuterium exchange: The convenient preparation of isotopically labelled analogues for stable isotope dilution analysis of volatile wine phenols
by Crump, Anna M and Sefton, Mark A and Wilkinson, Kerry L
Food chemistry, ISSN 0308-8146, 11/2014, Volume 162, pp. 261 - 263
Isotope labelling | Volatile phenols | Microwave-assisted deuterium exchange | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Nutrition & Dietetics | Food Science & Technology | Science & Technology | Biological and medical sciences | Toxicology | Medical sciences | Alcoholism and acute alcohol poisoning | Food toxicology | Deuterium | Reproducibility of Results | Volatile Organic Compounds - analysis | Benzaldehydes | Eugenol | Wine - analysis | Isotope Labeling - methods | Phenols - analysis | Cresols | Guaiacol - analogs & derivatives | Indicator Dilution Techniques | Mass Spectrometry - methods | Microwaves | Phenols | Index Medicus
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8. Full Text DM-1, sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phenolate: a curcumin analog with a synergic effect in combination with paclitaxel in breast cancer treatment
by Faião-Flores, Fernanda and Faião-Flores, Fernanda and Suarez, José Agustín Quincoces and Suarez, José Agustín Quincoces and Pardi, Paulo Celso and Pardi, Paulo Celso and Maria, Durvanei Augusto and Maria, Durvanei Augusto
Tumor biology, ISSN 1010-4283, 6/2012, Volume 33, Issue 3, pp. 775 - 785
Adjuvant antitumor therapy | Biomedicine | Phenolate DM-1 | Paclitaxel | Cancer Research | Metastatic breast cancer | Curcumin analog | Apoptosis | PhenolateDM-1 | Life Sciences & Biomedicine | Oncology | Science & Technology | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Apoptosis - drug effects | Guaiacol - administration & dosage | Caspase 3 - metabolism | Guaiacol - pharmacology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Neoplasm Metastasis | Guaiacol - therapeutic use | Guaiacol - analogs & derivatives | Mammary Neoplasms, Experimental - pathology | Female | Ketones - therapeutic use | Paclitaxel - administration & dosage | Mammary Neoplasms, Experimental - drug therapy | Ketones - pharmacology | Mammary Neoplasms, Experimental - mortality | Ketones - administration & dosage | Adenocarcinoma - drug therapy | Animals | Tumor Burden - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Survival Analysis | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Adenocarcinoma - mortality | Care and treatment | Adjuvant treatment | Breast cancer | Metastasis | Antineoplastic agents | Antimitotic agents | Chemotherapy | Analysis | Universities and colleges | Drug therapy | Tumors | Cancer | Rodents | Index Medicus
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9. Full Text Synthesis, biological evaluation, and docking studies of gigantol analogs as calmodulin inhibitors
by Reyes-Ramírez, Adelfo and Leyte-Lugo, Martha and Figueroa, Mario and Serrano-Alba, Trinidad and González-Andrade, Martín and Mata, Rachel
European journal of medicinal chemistry, ISSN 0223-5234, 2011, Volume 46, Issue 7, pp. 2699 - 2708
1,3-Diphenylpropenones | Gigantol | 1,2-Diphenylethanes | Calmodulin | 1,3-Diphenylpropanes | Biological and medical sciences | Miscellaneous | Medical sciences | Pharmacology. Drug treatments | Cyclic Nucleotide Phosphodiesterases, Type 1 - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Bibenzyls - chemistry | Antipsychotic Agents - chemical synthesis | Cyclic Nucleotide Phosphodiesterases, Type 1 - antagonists & inhibitors | Antidepressive Agents - chemistry | Guaiacol - analogs & derivatives | Guaiacol - chemical synthesis | Parasympatholytics - chemical synthesis | Guaiacol - chemistry | Biphenyl Compounds - chemistry | Calmodulin - chemistry | Parasympatholytics - chemistry | Anesthetics, Local - chemistry | Chlorpromazine - chemistry | Trifluoperazine - chemistry | Antineoplastic Agents - chemistry | Bibenzyls - chemical synthesis | Antipsychotic Agents - chemistry | Biphenyl Compounds - chemical synthesis | Biosensing Techniques | Antidepressive Agents - chemical synthesis | Protein Binding | Molecular Docking Simulation | Anesthetics, Local - chemical synthesis | Calmodulin - antagonists & inhibitors | Index Medicus
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10. Hydrodeoxygenation of phenolics in liquid phase over supported MoO3 and carburized analogues
by Lødeng, Rune and Ranga, Chanakya and Rajkhowa, Tapas and Alexiadis, Vaios I and Bjørkan, Hilde and Chytil, Svatopluk and Svenum, Ingeborg H and Walmsley, John and Thybaut, Joris W
Biomass Conversion and Biorefinery, ISSN 2190-6815, 09/2017, Volume 7, Issue 3, pp. 343 - 359
Guaiacol | Phenol | Hydrodeoxygenation | Anisole | Bio-oil | Molybdenum oxide | Catalysis | Kinetics | Engineering | Engineering, Chemical | Technology | Energy & Fuels | Science & Technology
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11. Full Text Simultaneous Electroanalysis of Guaiacol and its Analogs Based on their Differential Complexation with α‐Cyclodextrin on Nafion Modified Boron‐doped Diamond Electrode
by Hayes, Phyllis E and Glennon, Jeremy D and Buzid, Alyah and Luong, John H. T
Electroanalysis (New York, N.Y.), ISSN 1040-0397, 01/2020, Volume 32, Issue 1, pp. 119 - 127
Phenols | Boron-doped diamond electrode | Guaiacols | Cresol isomers | Whiskey | Electrochemistry | Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology
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12. Full Text Curcumin analogue identified as hyaluronan export inhibitor by virtual docking to the ABC transporter MRP5
by Prehm, Peter
Food and chemical toxicology, ISSN 0278-6915, 12/2013, Volume 62, pp. 76 - 81
Hyaluronan export inhibitor | Extracellular matrix | Virtual docking | MRP5 | Plasma membrane | Food Science & Technology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Ketones - pharmacology | Protein Structure, Tertiary | Guaiacol - metabolism | Curcumin - analogs & derivatives | Humans | Propiophenones - pharmacology | Multidrug Resistance-Associated Proteins - chemistry | Guaiacol - pharmacology | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | HEK293 Cells - drug effects | Guaiacol - analogs & derivatives | Hyaluronic Acid - metabolism | Inhibitory Concentration 50 | Protein Conformation | Biological Transport - drug effects | Flavonoids - pharmacology | Molecular Docking Simulation | Binding Sites | Ketones - metabolism | Multidrug Resistance-Associated Proteins - metabolism | Hyaluronic acid | International trade | Index Medicus
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13. Full Text The synthesis and tubulin binding activity of thiophene-based analogues of combretastatin A-4
by Flynn, Bernard L and Flynn, Guy P and Hamel, Ernest and Jung, M.Katherine
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2001, Volume 11, Issue 17, pp. 2341 - 2343
Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Colchicine - pharmacology | Guaiacol - metabolism | Humans | Colchicine - metabolism | Guaiacol - pharmacology | Thiophenes - pharmacology | Thiophenes - metabolism | Stilbenes - chemistry | Structure-Activity Relationship | Stilbenes - pharmacology | Antineoplastic Agents - chemistry | Breast Neoplasms - drug therapy | Tubulin - drug effects | Antineoplastic Agents - metabolism | Tubulin - metabolism | Guaiacol - analogs & derivatives | Guaiacol - chemistry | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Thiophenes - chemistry | Drug Screening Assays, Antitumor | Index Medicus
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14. Full Text Synthesis of a New [6]-Gingerol Analogue and Its Protective Effect with Respect to the Development of Metabolic Syndrome in Mice Fed a High-Fat Diet
by Okamoto, Mayumi and Irii, Hiroyuki and Tahara, Yu and Ishii, Hiroyuki and Hirao, Akiko and Udagawa, Haruhide and Hiramoto, Masaki and Yasuda, Kazuki and Takanishi, Atsuo and Shibata, Shigenobu and Shimizu, Isao
Journal of medicinal chemistry, ISSN 0022-2623, 09/2011, Volume 54, Issue 18, pp. 6295 - 6304
Metabolic Syndrome - etiology | Catechols - chemical synthesis | Amides - chemical synthesis | Fatty Alcohols - chemical synthesis | Leptin - metabolism | Body Weight - drug effects |