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PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 2, pp. e17108 - e17108
Commonly used antitumor treatments, including radiation and chemotherapy, function by damaging the DNA of rapidly proliferating cells. However, resistance to... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Oncogene Proteins - genetics | Guanine Nucleotide Exchange Factors - physiology | Humans | rhoB GTP-Binding Protein - antagonists & inhibitors | rhoB GTP-Binding Protein - physiology | rhoB GTP-Binding Protein - metabolism | Oncogene Proteins - physiology | Breast Neoplasms - metabolism | Cell Death - genetics | Guanine Nucleotide Exchange Factors - metabolism | DNA Damage - genetics | Female | Cell Death - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | rhoB GTP-Binding Protein - genetics | Carcinoma - pathology | DNA Damage - drug effects | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Guanine Nucleotide Exchange Factors - genetics | RNA, Small Interfering - pharmacology | Oncogene Proteins - metabolism | Proto-Oncogene Proteins - genetics | Oncogene Proteins - antagonists & inhibitors | Breast Neoplasms - genetics | Guanine Nucleotide Exchange Factors - antagonists & inhibitors | Breast Neoplasms - pathology | Proto-Oncogene Proteins - physiology | Carcinoma - genetics | Carcinoma - metabolism | HeLa Cells | Cell Line, Transformed | Chemotherapy | Ionizing radiation | Cell death | DNA damage | DNA | Biochemistry | G proteins | Cervical cancer | Guanine | Cancer | Cytochrome | Biotechnology | Transcription factors | Phosphorylation | Genotoxicity | Radiation | Kinases | Cancer therapies | Proteins | Tumorigenesis | Guanine nucleotide exchange factor | Localization | Growth factors | Deoxyribonucleic acid--DNA | Stresses | Developmental biology | Mortality | c-Jun protein | I.R. radiation | siRNA | Breast cancer | Tumor cell lines | Gene expression | Cervix | Stress | Signaling | Reagents | Ligands | Radiation damage | BIM protein | Apoptosis | Tumors | Index Medicus | Deoxyribonucleic acid
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 06/2013, Volume 110, Issue 25, pp. 10201 - 10206
Journal Article
PloS one, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, pp. e0155292 - e0155292
.... However, the mechanisms whereby Akt2 regulates Rac1 activity remain obscure. The guanine nucleotide exchange factor FLJ00068 has been identified as a direct regulator... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | RNA, Small Interfering - genetics | Cell Fractionation | Glucose Transporter Type 4 - metabolism | Male | Muscle, Skeletal - metabolism | Muscle, Skeletal - cytology | Proto-Oncogene Proteins c-akt - genetics | Myoblasts - metabolism | Guanine Nucleotide Exchange Factors - metabolism | Myoblasts - cytology | Neuropeptides - genetics | Insulin - genetics | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | Guanine Nucleotide Exchange Factors - genetics | Glucose Transporter Type 4 - genetics | Signal Transduction | Tissue Culture Techniques | Mice, Inbred C57BL | Gene Expression Regulation | Neuropeptides - metabolism | Protein Transport | Insulin - metabolism | Animals | Guanine Nucleotide Exchange Factors - antagonists & inhibitors | Mice | rac1 GTP-Binding Protein - metabolism | RNA, Small Interfering - metabolism | rac1 GTP-Binding Protein - genetics | Physiological aspects | Muscles | Glucose metabolism | Research | Insulin | Guanine | Phosphorylation | Laboratories | Science | Immunoblotting | Stimulation | Activation | Biology | Adipocytes | Glucose | Kinases | Proteins | Rodents | Gastrocnemius muscle | Guanine nucleotide exchange factor | Localization | Polyclonal antibodies | Glucose transporter | Sarcolemma | Translocation | Fractionation | AKT2 protein | Rac1 protein | Guanosine triphosphatases | siRNA | Gene expression | Ribonucleic acid--RNA | Skeletal muscle | Mutants | Myoblasts | Musculoskeletal system | Signaling | Microscopy | Protein kinase | Transporter | Index Medicus | RNA | Ribonucleic acid
Journal Article
Oncogene, ISSN 1476-5594, 12/2013, Volume 34, Issue 2, pp. 188 - 198
Journal Article