X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1423) 1423
Publication (345) 345
Book Review (20) 20
Book / eBook (11) 11
Book Chapter (10) 10
Dissertation (5) 5
Conference Proceeding (2) 2
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (898) 898
animals (862) 862
humans (780) 780
mice (530) 530
guanine nucleotide exchange factors - genetics (490) 490
guanine nucleotide exchange factors - metabolism (443) 443
cell biology (378) 378
signal transduction (332) 332
proteins (291) 291
biochemistry & molecular biology (290) 290
male (286) 286
female (282) 282
mice, knockout (259) 259
mutation (246) 246
article (231) 231
guanine nucleotide exchange factors - deficiency (220) 220
immunology (201) 201
activation (196) 196
phosphorylation (171) 171
mice, inbred c57bl (169) 169
guanine (162) 162
research (161) 161
guanine nucleotide exchange factor (144) 144
genetic aspects (141) 141
neurosciences (141) 141
analysis (139) 139
cells, cultured (135) 135
research article (133) 133
genetics & heredity (131) 131
gene expression (128) 128
kinases (123) 123
expression (120) 120
guanine nucleotide exchange factors - physiology (117) 117
multidisciplinary sciences (116) 116
physiological aspects (115) 115
cell line (113) 113
protein binding (113) 113
guanine nucleotide exchange factors (111) 111
nucleotide exchange factor (108) 108
phenotype (108) 108
protein (107) 107
g proteins (105) 105
molecular sequence data (99) 99
cancer (94) 94
guanine-nucleotide exchange (94) 94
biology (92) 92
genes (92) 92
medicine (91) 91
disease models, animal (90) 90
mutations (90) 90
abridged index medicus (87) 87
rats (86) 86
child (85) 85
rho guanine nucleotide exchange factors (83) 83
rodents (83) 83
cells (82) 82
signal transduction - physiology (81) 81
oncology (80) 80
science (80) 80
cell line, tumor (77) 77
cytoskeleton (76) 76
amino acid sequence (75) 75
guanine nucleotide exchange factors - immunology (75) 75
cell proliferation (74) 74
lymphocytes (73) 73
gene expression regulation (72) 72
actin (71) 71
hematology (71) 71
molecular biology (71) 71
neurons (71) 71
health aspects (69) 69
models, biological (69) 69
rho-gtpases (69) 69
base sequence (68) 68
in-vivo (67) 67
child, preschool (64) 64
adult (63) 63
apoptosis (63) 63
genetics (63) 63
migration (61) 61
physiology (61) 61
mice, transgenic (60) 60
mutation - genetics (60) 60
rac1 gtp-binding protein - metabolism (60) 60
adolescent (59) 59
actins - metabolism (58) 58
medicine, research & experimental (57) 57
rho gtp-binding proteins - metabolism (57) 57
cell movement (56) 56
transfection (56) 56
biophysics (55) 55
immunodeficiency (55) 55
t cells (55) 55
developmental biology (54) 54
protein transport (54) 54
receptor (54) 54
articles (53) 53
disease (53) 53
gene (53) 53
life sciences (53) 53
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 402 - 412
Background Mutations in dedicator of cytokinesis 8 (DOCK8) cause a combined immunodeficiency (CID) also classified as autosomal recessive (AR) hyper-IgE... 
Allergy and Immunology | Primary combined immunodeficiency | autosomal recessive hyper-IgE syndrome | signal transducer and activator of transcription 3 | Molluscum contagiosum | hyper-IgE syndrome | dedicator of cytokinesis 8 | SURVIVAL | BONE-MARROW-TRANSPLANTATION | STAT3 | GLYCOSYLATION | IMMUNOLOGY | ALLERGY | DOCK8 DEFICIENCY | DISORDER | MUTATIONS | STEM-CELL TRANSPLANTATION | IMMUNODEFICIENCY | Job Syndrome - genetics | Job Syndrome - mortality | Humans | Middle Aged | Child, Preschool | Male | Support Vector Machine | Virus Diseases - complications | Eosinophils - immunology | Immunoglobulin E - blood | CD4-Positive T-Lymphocytes - immunology | Bacterial Infections - genetics | Eosinophils - pathology | Virus Diseases - genetics | Child | Guanine Nucleotide Exchange Factors - deficiency | STAT3 Transcription Factor - genetics | Skin Diseases - mortality | Immunoglobulin M - genetics | Guanine Nucleotide Exchange Factors - genetics | Virus Diseases - immunology | Skin Diseases - immunology | Antigens, Viral - immunology | Phenotype | Skin Diseases - complications | Job Syndrome - complications | Adolescent | Survival Analysis | Virus Diseases - mortality | Mutation | STAT3 Transcription Factor - immunology | CD8-Positive T-Lymphocytes - immunology | Bacterial Infections - mortality | Job Syndrome - immunology | CD8-Positive T-Lymphocytes - pathology | Skin Diseases - genetics | Antigens, Bacterial - immunology | Infant | Antigens, Bacterial - blood | CD4-Positive T-Lymphocytes - pathology | Antigens, Viral - blood | Bacterial Infections - complications | Immunoglobulin E - genetics | Bacterial Infections - immunology | Adult | Female | Immunoglobulin M - blood | Guanine Nucleotide Exchange Factors - immunology | Lymphocyte Count | Genotype & phenotype | Immunoglobulins | Laboratories | Lymphocytes | Families & family life | Lymphomas | Viral infections | Deoxyribonucleic acid--DNA | Immunoglobulin M | Immunoglobulin E | CD8-Positive T-Lymphocytes | Life Sciences | Antigens, Viral | Bacterial Infections | Job Syndrome | CD4-Positive T-Lymphocytes | Virus Diseases | Skin Diseases | Antigens, Bacterial | Guanine Nucleotide Exchange Factors | STAT3 Transcription Factor | Eosinophils
Journal Article
Nature, ISSN 0028-0836, 02/2009, Volume 457, Issue 7233, pp. 1103 - 1108
Angiogenesis is controlled by physical interactions between cells and extracellular matrix as well as soluble angiogenic factors, such as VEGF. However, the... 
RETINAL NEOVASCULARIZATION | REGULATORY NETWORKS | VEGF | MULTIDISCIPLINARY SCIENCES | CYTOSKELETAL TENSION | GEOMETRIC CONTROL | EXTRACELLULAR-MATRIX | LINEAGE SPECIFICATION | CELL-SHAPE | TFII-I | ENDOTHELIAL GROWTH-FACTOR | Endothelium, Vascular - cytology | Up-Regulation | Humans | Transcription Factors - deficiency | Extracellular Matrix - metabolism | Vascular Endothelial Growth Factor A - metabolism | Gene Knockdown Techniques | Vascular Endothelial Growth Factor Receptor-2 - genetics | Guanine Nucleotide Exchange Factors - metabolism | Transcription, Genetic | Vascular Endothelial Growth Factor Receptor-2 - biosynthesis | Guanine Nucleotide Exchange Factors - deficiency | Repressor Proteins - metabolism | Animals, Newborn | Cell Line | Guanine Nucleotide Exchange Factors - genetics | Retinal Vessels - metabolism | Signal Transduction | Endothelial Cells - metabolism | Neovascularization, Physiologic - genetics | Mice, Inbred C57BL | Repressor Proteins - genetics | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Transcription Factors - genetics | Endothelium, Vascular - growth & development | Transcription Factors - metabolism | Neovascularization, Physiologic - physiology | Animals | Retinal Vessels - growth & development | GATA2 Transcription Factor - metabolism | Transcription Factors, TFII - metabolism | Mice | Physiological aspects | Cell receptors | Research | Neovascularization | Genetic transcription | DNA binding proteins | Cell division | Angiogenesis | Chemical reactions | Neurons | Cells | VEGFR2 | capillary endothelial cell | p190RhoGAP | mechanotransduction | angiogenesis | GATA2
Journal Article
Journal of clinical immunology, ISSN 0271-9142, 2015, Volume 35, Issue 2, pp. 189 - 198
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 25, pp. 2409 - 2422
Journal Article
Developmental Cell, ISSN 1534-5807, 07/2010, Volume 19, Issue 1, pp. 138 - 147
The mammalian PCP pathway regulates diverse developmental processes requiring coordinated cellular movement, including neural tube closure and cochlear... 
CELLBIO | DEVBIO | Devbio | Cellbio | RHO-FAMILY GTPASES | DEVELOPMENTAL TRANSCRIPTION FACTORS | GRAINY-HEAD | NEURAL-TUBE DEFECTS | LEADING-EDGE | LOOP-TAIL | TRIPLE-HELIX REPEAT | XENOPUS GASTRULATION | DEVELOPMENTAL BIOLOGY | DROSOPHILA | PCP PATHWAY | CELL BIOLOGY | Guanine Nucleotide Exchange Factors - physiology | Nerve Tissue Proteins - deficiency | Transcription Factors - deficiency | Actins - metabolism | DNA-Binding Proteins - deficiency | Mice, Mutant Strains | Epidermis - injuries | Female | Wound Healing - genetics | Guanine Nucleotide Exchange Factors - deficiency | DNA-Binding Proteins - physiology | Guanine Nucleotide Exchange Factors - genetics | Nerve Tissue Proteins - physiology | Transcription Factors - physiology | Signal Transduction | Keratinocytes - cytology | Rho Guanine Nucleotide Exchange Factors | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Mice, Knockout | Pregnancy | Animals | Models, Biological | Epidermis - physiology | Epidermis - embryology | Cell Polarity - physiology | Mice | Wound Healing - physiology | Mutation | Keratinocytes - physiology | Animal genetics | Care and treatment | Oncology, Experimental | Polymerization | Research | Muscle proteins | Gene expression | Amphibians | Wounds and injuries | Gene mutations | Actin | Analysis | Cancer
Journal Article
Nature Communications, ISSN 2041-1723, 01/2017, Volume 8, Issue 1, p. 13946
Mutations of DOCK8 in humans cause a combined immunodeficiency characterized by atopic dermatitis with high serum IgE levels. However, the molecular link... 
COMBINED IMMUNODEFICIENCY | INHIBITION | T-CELL SURVIVAL | MST1 DEFICIENCY | DERMATITIS | MULTIDISCIPLINARY SCIENCES | RECEPTOR | HYPER-IGE SYNDROMES | MICE | CYTOKINESIS 8 DEFICIENCY | HYPOXIA-INDUCIBLE FACTORS | Cell Nucleus - immunology | Dermatitis, Atopic - genetics | Cytosol - immunology | Male | Sp1 Transcription Factor - immunology | CD4-Positive T-Lymphocytes - pathology | CD4-Positive T-Lymphocytes - immunology | Interleukins - genetics | Cell Nucleus - metabolism | Immunoglobulin E - immunology | Immunoglobulin E - genetics | Interleukins - immunology | Dermatitis, Atopic - immunology | Female | Active Transport, Cell Nucleus | Basic Helix-Loop-Helix Transcription Factors - deficiency | Guanine Nucleotide Exchange Factors - deficiency | Disease Models, Animal | Promoter Regions, Genetic | Guanine Nucleotide Exchange Factors - genetics | Basic Helix-Loop-Helix Transcription Factors - genetics | Signal Transduction | Aryl Hydrocarbon Receptor Nuclear Translocator - immunology | Gene Expression Regulation | Dermatitis, Atopic - pathology | Mice, Knockout | Protein Transport | Animals | Sp1 Transcription Factor - genetics | Guanine Nucleotide Exchange Factors - immunology | Basic Helix-Loop-Helix Transcription Factors - immunology | Cytosol - metabolism | Heterozygote | Aryl Hydrocarbon Receptor Nuclear Translocator - genetics | Mice
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2017, Volume 198, Issue 5, pp. 1887 - 1899
In myelodysplastic syndromes (MDS), functional defects of neutrophils result in high mortality because of infections; however, the molecular basis remains... 
INHIBITS MIGRATION | TOOTH TYPE 4H | SUPEROXIDE-PRODUCTION | PEPTIDE-STIMULATED NEUTROPHILS | DOCK8 DEFICIENCY | IMMUNOLOGY | RHO-GTPASES | OXIDASE COMPONENTS | SIGNAL-REGULATED KINASE | PHOSPHOLIPASE-D ACTIVATION | NUCLEOTIDE EXCHANGE FACTORS | Chemotaxis, Leukocyte | Cell Proliferation | Humans | Middle Aged | Male | rac1 GTP-Binding Protein - immunology | cdc42 GTP-Binding Protein - immunology | Guanine Nucleotide Exchange Factors - metabolism | Aged, 80 and over | Female | Microfilament Proteins - metabolism | Chemotaxis - immunology | Microfilament Proteins - genetics | Guanine Nucleotide Exchange Factors - deficiency | Guanine Nucleotide Exchange Factors - genetics | Microfilament Proteins - deficiency | Neutrophil Activation | Neutrophils - immunology | Neutrophils - physiology | MicroRNAs - immunology | cdc42 GTP-Binding Protein - genetics | Guanine Nucleotide Exchange Factors - immunology | HL-60 Cells | Aged | MicroRNAs - genetics | RNA, Small Interfering | MicroRNAs - physiology | Interleukin-8 - immunology | Myelodysplastic Syndromes - immunology | rac1 GTP-Binding Protein - genetics | Cdc42 protein | Chemotactic factors | Leukocyte migration | Neutrophils | MiRNA | Disorders | Rac1 protein | Activation | Leukocytes (neutrophilic) | siRNA | Cytokinesis | Ribonucleic acid--RNA | Myelodysplastic syndrome | Guanine | Proteins | Cell activation | MicroRNAs | Degranulation | Attenuation | Aberration | Guanine nucleotide exchange factor | Cell migration | Interleukin 8
Journal Article
Blood, ISSN 0006-4971, 09/2016, Volume 128, Issue 9, pp. 1165 - 1167
In this issue of Blood, Lozano et al describe 3 patients, belonging to 2 unrelated families, with severe inherited platelet dysfunction and bleeding diathesis,... 
ACTIVATION | HEMATOLOGY | REPRESENT | MUTATION | Platelet Aggregation | Humans | Guanine Nucleotide Exchange Factors - deficiency | rap1 GTP-Binding Proteins
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 131, Issue 3, pp. 840 - 848
Journal Article