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Science (American Association for the Advancement of Science), ISSN 1095-9203, 03/2018, Volume 359, Issue 6383, p. eaaq0939
.... Phosphorylation converts eIF2 from a substrate to a competitive inhibitor of its dedicated guanine nucleotide exchange factor, eIF2B, thereby inhibiting translation... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Memory - drug effects | Phosphorylation | Recombinant Proteins - ultrastructure | Escherichia coli | Humans | Cyclohexylamines - chemistry | Recombinant Proteins - chemistry | Acetamides - pharmacology | Recombinant Proteins - genetics | Nootropic Agents - chemistry | Protein Folding | Cryoelectron Microscopy | Eukaryotic Initiation Factor-2B - chemistry | Acetamides - chemistry | Cyclohexylamines - pharmacology | Protein Stability - drug effects | Eukaryotic Initiation Factor-2B - genetics | Protein Conformation | Eukaryotic Initiation Factor-2B - ultrastructure | Mutation | Nootropic Agents - pharmacology | Protein Multimerization - drug effects | Neuroimaging | Exchanging | Brain | Regulations | Atomic force microscopy | Traumatic brain injury | Target recognition | Disorders | Cognitive ability | Nervous system | Cognition | Ultracentrifugation | Guanine | Convergence | Analogs | Proteins | Head injuries | Synthesis | Rodents | Atomic structure | Guanine nucleotide exchange factor | Stress response | Dimerization | Assembly | Symmetry | Stresses | Enzymes | Translation | Translation initiation | Pharmacology | Electron microscopy | Sedimentation | Chemical compounds | Substrates | Mutants | Neurological diseases | Transmission electron microscopy | Composite materials | Inhibitors | Cognition & reasoning | Microscopy | Ionic strength | Dismantling | Binding sites | Index Medicus
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 12/2016, Volume 126, Issue 12, pp. 4497 - 4515
Journal Article