X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4083) 4083
Publication (476) 476
Book Review (45) 45
Book Chapter (17) 17
Newsletter (16) 16
Conference Proceeding (6) 6
Dissertation (2) 2
Magazine Article (2) 2
Transcript (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (3091) 3091
male (1593) 1593
rats (1467) 1467
guanylate cyclase - antagonists & inhibitors (1409) 1409
nitric oxide (1385) 1385
guanylate cyclase - metabolism (1252) 1252
humans (1146) 1146
enzyme inhibitors - pharmacology (1107) 1107
index medicus (1103) 1103
pharmacology & pharmacy (960) 960
cyclic gmp - metabolism (951) 951
nitric oxide - metabolism (812) 812
guanylate cyclase (760) 760
in vitro techniques (702) 702
guanylate-cyclase (672) 672
nitric-oxide (653) 653
nitric oxide synthase - antagonists & inhibitors (601) 601
biochemistry & molecular biology (597) 597
female (597) 597
neurosciences (574) 574
nitric oxide - physiology (535) 535
physiology (534) 534
dose-response relationship, drug (533) 533
mice (507) 507
cells, cultured (495) 495
soluble guanylate-cyclase (489) 489
rats, sprague-dawley (485) 485
rats, wistar (482) 482
cgmp (481) 481
soluble guanylyl cyclase (462) 462
oxadiazoles - pharmacology (458) 458
activation (440) 440
quinoxalines - pharmacology (433) 433
cyclic-gmp (412) 412
nitric-oxide synthase (410) 410
nitric oxide donors - pharmacology (393) 393
nitroprusside - pharmacology (391) 391
signal transduction (346) 346
cyclic gmp (342) 342
ng-nitroarginine methyl ester - pharmacology (341) 341
cardiac & cardiovascular systems (333) 333
nitric oxide synthase - metabolism (323) 323
vasodilator agents - pharmacology (313) 313
inhibition (302) 302
cell biology (301) 301
cyclic gmp - pharmacology (300) 300
vasodilation - drug effects (296) 296
arginine - pharmacology (293) 293
cells (291) 291
expression (288) 288
smooth-muscle (288) 288
l-arginine (287) 287
signal transduction - drug effects (280) 280
nitric oxide - pharmacology (278) 278
relaxing factor (278) 278
endothelium (275) 275
nitric oxide synthase (270) 270
cyclic gmp - physiology (269) 269
cyclic gmp - analogs & derivatives (265) 265
muscle, smooth, vascular - drug effects (254) 254
peripheral vascular disease (244) 244
physiological aspects (244) 244
calcium - metabolism (240) 240
receptors, cytoplasmic and nuclear - metabolism (240) 240
methylene blue - pharmacology (235) 235
relaxation (235) 235
research (224) 224
rat (223) 223
hypertension (222) 222
guanylyl cyclase (220) 220
signal transduction - physiology (214) 214
arginine - analogs & derivatives (211) 211
muscle relaxation - drug effects (211) 211
dependent protein-kinase (208) 208
enzyme activation - drug effects (205) 205
kinetics (204) 204
aminoquinolines - pharmacology (202) 202
vascular smooth-muscle (201) 201
phosphorylation (199) 199
atrial natriuretic factor - pharmacology (193) 193
cattle (192) 192
synthase (191) 191
endothelium, vascular - drug effects (189) 189
enzyme activation (183) 183
guanylate cyclase - physiology (182) 182
analysis (181) 181
neurons (180) 180
time factors (178) 178
rabbits (177) 177
receptors, cytoplasmic and nuclear - antagonists & inhibitors (172) 172
blood pressure - drug effects (171) 171
receptor (171) 171
article (170) 170
cyclic gmp - biosynthesis (170) 170
guanylate cyclase - genetics (169) 169
brain (167) 167
cyclic amp - metabolism (167) 167
endocrinology & metabolism (167) 167
endothelial-cells (167) 167
nitric oxide - antagonists & inhibitors (163) 163
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4044) 4044
Russian (24) 24
German (18) 18
Japanese (7) 7
Chinese (5) 5
French (4) 4
Polish (4) 4
Spanish (3) 3
Ukrainian (2) 2
Dutch (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e42623
The prevalence of diabetes mellitus and its complications, such as diabetic nephropathy (DN), is rising worldwide and prevention and treatment are therefore... 
FIBROSIS | ANTI-THY1 GLOMERULONEPHRITIS | TELMISARTAN | OXIDATIVE STRESS | NITRIC-OXIDE SYNTHASE | BIOLOGY | CARDIOVASCULAR-DISEASE | GLOMERULAR-LESIONS | RISK | HYPERTENSIVE-RATS | GENE POLYMORPHISM | Receptors, Angiotensin - metabolism | Diabetic Nephropathies - drug therapy | Male | Guanylate Cyclase - antagonists & inhibitors | Angiotensin II Type 1 Receptor Blockers - pharmacology | Kidney Function Tests | Benzimidazoles - administration & dosage | Blood Pressure - drug effects | Nitric Oxide Synthase Type III - metabolism | Angiotensin II Type 1 Receptor Blockers - administration & dosage | Disease Models, Animal | Pyrazoles - pharmacology | Pyrimidines - administration & dosage | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Diabetic Nephropathies - genetics | Guanylate Cyclase - metabolism | Soluble Guanylyl Cyclase | Biomarkers - blood | Pyrimidines - pharmacology | Nitric Oxide Synthase Type III - genetics | Benzoates - administration & dosage | Diabetic Nephropathies - mortality | Mice, Knockout | Blood Glucose - drug effects | Organ Size - drug effects | Pyrazoles - administration & dosage | Animals | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Benzoates - pharmacology | Benzimidazoles - pharmacology | Mice | Receptors, Cytoplasmic and Nuclear - metabolism | Hypertension | Analysis | Diabetic nephropathies | Angiotensin | Albumin | Health aspects | Diabetic retinopathy | Oxidative stress | Transplants & implants | Streptozocin | Science | Stimulation | Kinases | Guanylate cyclase | Blood | Stimulators | Reduction | Rodents | Blood pressure | Angiotensin II | Heart diseases | Enzymes | Excretion | Statistical analysis | Complications | Diabetes mellitus | Bioavailability | Patients | Malondialdehyde | Nephropathy | Nitric oxide | Combined treatment | Diabetes | Immunoreactivity | Laboratory animals | Structure-function relationships
Journal Article
Journal Article
The Journal of Physiology, ISSN 0022-3751, 12/2017, Volume 595, Issue 24, pp. 7427 - 7439
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 02/2014, Volume 348, Issue 2, pp. 260 - 270
Hyperglycemia and endothelial dysfunction are associated with hypertension, but the specific causality and genetic underpinning are unclear. Caveolin-1 (cav-1)... 
DIABETES-MELLITUS | ACTIVATED PROTEIN-KINASE | LIPID-METABOLISM | NITRIC-OXIDE SYNTHASE | II TYPE-1 RECEPTOR | INSULIN-RESISTANCE | ENDOTHELIAL-CELLS | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | GUANYLATE-CYCLASE | ADIPOSE-TISSUE | AMP-Activated Protein Kinases - metabolism | Metformin - therapeutic use | Muscle, Smooth, Vascular - metabolism | Endothelium, Vascular - drug effects | Male | Guanylate Cyclase - antagonists & inhibitors | Aorta - metabolism | Hyperglycemia - drug therapy | Muscle, Smooth, Vascular - physiopathology | Hypertension - etiology | Nitric Oxide Synthase Type III - chemistry | Protein Processing, Post-Translational - drug effects | Hypertension - prevention & control | Aorta - physiopathology | Nitric Oxide Synthase Type III - metabolism | Phosphorylation - drug effects | Hyperglycemia - physiopathology | Guanylate Cyclase - chemistry | Muscle, Smooth, Vascular - drug effects | Hypoglycemic Agents - therapeutic use | AMP-Activated Protein Kinases - antagonists & inhibitors | Aorta - drug effects | Endothelium, Vascular - physiopathology | Enzyme Inhibitors - pharmacology | Caveolin 1 - genetics | Guanylate Cyclase - metabolism | Vasoconstriction - drug effects | AMP-Activated Protein Kinases - chemistry | Hypertension - metabolism | Mice, Knockout | Nitric Oxide Synthase Type III - antagonists & inhibitors | Caveolin 1 - metabolism | Hyperglycemia - metabolism | Animals | Hyperglycemia - blood | Endothelium, Vascular - metabolism | Mice | Vasodilation - drug effects | Cardiovascular
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 08/2008, Volume 295, Issue 2, pp. 499 - 508
Nitric oxide (NO) has been shown to be the endothelium-derived relaxing factor (EDRF), and its impairment contributes to a variety of cardiovascular disorders.... 
Blood pressure | Vasorelaxation | Heme proteins | Aerobic nitrite reduction | Soluble guanylate cyclase | blood pressure | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ORGANIC NITRATES | DEPENDENT VASODILATION | heme proteins | RELAXING FACTOR | S-NITROSOHEMOGLOBIN | soluble guanylate cyclase | aerobic nitrite reduction | GLOBIN FAMILY | SOLUBLE GUANYLYL CYCLASE | XANTHINE-OXIDASE | vasorelaxation | SYNTHASE ACTIVITY | PERIPHERAL VASCULAR DISEASE | CYTOCHROME-P-450 ENZYMES | BIOLOGICAL-SYSTEMS | Blood Pressure | Nitrites - metabolism | Male | Guanylate Cyclase - antagonists & inhibitors | Nitrites - administration & dosage | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Oxadiazoles - pharmacology | Aorta, Thoracic - drug effects | Hemeproteins - antagonists & inhibitors | Heart Rate | Oxyhemoglobins - metabolism | Electron Spin Resonance Spectroscopy | Signal Transduction | Hemeproteins - metabolism | Enzyme Inhibitors - pharmacology | Aorta, Thoracic - metabolism | Rats | Guanylate Cyclase - metabolism | Soluble Guanylyl Cyclase | Rats, Sprague-Dawley | Aorta, Thoracic - enzymology | Animals | Endothelium-Dependent Relaxing Factors - metabolism | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Infusions, Intravenous | Vasodilation - drug effects | Electrochemistry - methods | In Vitro Techniques | Nitric Oxide - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 2015, Volume 308, Issue 8, pp. E621 - E630
We hypothesized that carbon monoxide (CO) might suppress chronic inflammation, which led to metabolic disturbances. Ovariectomy (OVX) was performed in mice to... 
Insulin resistance | Loss of ovarian function | Adipose tissue inflammation | Carbon monoxide | CD11c | METABOLIC SYNDROME | ACTIVATION | PHYSIOLOGY | adipose tissue inflammation | carbon monoxide | SENSITIVITY | DIET-INDUCED OBESITY | BONE LOSS | ENDOCRINOLOGY & METABOLISM | loss of ovarian function | HYDROGEN-PEROXIDE | MICE | HEME OXYGENASE-1 | STRESS | insulin resistance | UP-REGULATION | Prodrugs - administration & dosage | Ovariectomy - adverse effects | Heme Oxygenase-1 - metabolism | Reactive Oxygen Species - metabolism | Adipose Tissue, White - immunology | Adipose Tissue, White - metabolism | Guanylate Cyclase - antagonists & inhibitors | Cyclic GMP - agonists | Heme Oxygenase-1 - genetics | Carbon Monoxide - pharmacology | RNA Interference | Aging | Organometallic Compounds - therapeutic use | Female | Panniculitis - immunology | Membrane Proteins - metabolism | Macrophages - immunology | Antimetabolites - pharmacology | Adipose Tissue, White - pathology | Panniculitis - prevention & control | Adiposity - drug effects | Specific Pathogen-Free Organisms | Membrane Proteins - genetics | Mice, Inbred C57BL | Cells, Cultured | Injections, Intraperitoneal | Insulin Resistance | Guanylate Cyclase - metabolism | Soluble Guanylyl Cyclase | Receptors, Cytoplasmic and Nuclear - genetics | Heme Oxygenase-1 - antagonists & inhibitors | Macrophages - metabolism | Reactive Oxygen Species - antagonists & inhibitors | Animals | Cyclic GMP - metabolism | Membrane Proteins - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Guanylate Cyclase - genetics | Macrophages - drug effects | Prodrugs - therapeutic use | Panniculitis - pathology | Prodrugs - pharmacology | Adipose Tissue, White - drug effects | Organometallic Compounds - pharmacology | Panniculitis - metabolism | Organometallic Compounds - administration & dosage | Receptors, Cytoplasmic and Nuclear - metabolism | Adipose tissues | Care and treatment | Abnormalities | Inflammation | Postmenopausal women | Properties | Health aspects
Journal Article
Journal Article
Journal Article
Physiology & Behavior, ISSN 0031-9384, 2014, Volume 139, pp. 267 - 273
Journal Article
Microcirculation, ISSN 1073-9688, 10/2014, Volume 21, Issue 7, pp. 640 - 648
Journal Article