X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (2697) 2697
pharmacology & pharmacy (2205) 2205
neurosciences (1937) 1937
male (1797) 1797
rats (1724) 1724
humans (919) 919
brain (849) 849
rat-brain (848) 848
biochemistry & molecular biology (789) 789
rats, sprague-dawley (654) 654
index medicus (555) 555
female (544) 544
binding (534) 534
histamine (519) 519
brain - metabolism (508) 508
mice (478) 478
rats, wistar (473) 473
rat (468) 468
release (468) 468
in vitro techniques (462) 462
dose-response relationship, drug (449) 449
binding-sites (433) 433
autoradiography (430) 430
ligands (426) 426
inhibition (401) 401
chemistry, medicinal (396) 396
receptor (381) 381
tritium (377) 377
receptors (366) 366
radioligand assay (358) 358
antagonists (351) 351
antagonist (347) 347
kinetics (335) 335
histamine h-3 receptor (328) 328
h-3 receptor (309) 309
binding sites (298) 298
dopamine (297) 297
neurons (278) 278
psychiatry (270) 270
brain - drug effects (264) 264
expression (263) 263
binding, competitive (255) 255
dopamine - metabolism (246) 246
serotonin (244) 244
cerebral cortex - metabolism (243) 243
central-nervous-system (241) 241
hippocampus (235) 235
potent (232) 232
sites (222) 222
receptors, n-methyl-d-aspartate - metabolism (214) 214
pharmacological characterization (207) 207
striatum (205) 205
in-vivo (204) 204
adult (201) 201
hippocampus - metabolism (197) 197
glutamate (194) 194
schizophrenia (191) 191
nmda receptor (189) 189
pharmacology (184) 184
agonist (183) 183
clinical neurology (183) 183
hippocampus - drug effects (181) 181
localization (176) 176
modulation (175) 175
chemistry, organic (172) 172
thioperamide (172) 172
time factors (165) 165
middle aged (164) 164
piperidines - pharmacology (164) 164
identification (161) 161
structure-activity relationship (161) 161
corpus striatum - metabolism (160) 160
guinea-pig (160) 160
cerebral-cortex (159) 159
high-affinity (159) 159
neurons - metabolism (155) 155
cloning (154) 154
activation (152) 152
alzheimers-disease (152) 152
cortex (152) 152
neurons - drug effects (152) 152
[ (151) 151
messenger-rna (151) 151
methyl-d-aspartate (151) 151
5-ht (150) 150
in-vitro (150) 150
membranes (150) 150
h-3 receptors (149) 149
acetylcholine (147) 147
receptors, serotonin - metabolism (146) 146
subtypes (145) 145
noradrenaline release (144) 144
h-3 mk-801 binding (142) 142
cerebral cortex - drug effects (140) 140
nucleus-accumbens (140) 140
physiology (139) 139
h-3 dopamine (138) 138
excitatory amino acid antagonists - pharmacology (137) 137
behavioral sciences (136) 136
brain histamine (134) 134
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Biological & pharmaceutical bulletin, ISSN 0918-6158, 12/2008, Volume 31, Issue 12, pp. 2163 - 2181
Within the recent years novel lead optimisations for histamine H_3 receptor antagonists made their way from bench to bedside. Structure-activity relationships,... 
cognition | PHARMACOLOGICAL CHARACTERIZATION | DRUG DISCOVERY | CONSTITUTIVE ACTIVITY | histamine H-3 | schizophrenia | NOREPINEPHRINE EXOCYTOSIS | sleep disorder | IN-VITRO | ELECTRICALLY-INDUCED CONVULSIONS | H-3-RECEPTOR ANTAGONISTS | AMYGDALOID-KINDLED SEIZURES | PHARMACOLOGY & PHARMACY | tiprolisant | RAT-BRAIN | HIGHLY POTENT | obesity
Journal Article
MOLECULES, ISSN 1420-3049, 11/2019, Volume 24, Issue 22, p. 4106
Epilepsy is a multifaceted neurological disorder which severely affects neuronal function. Some patients may experience status epilepticus (SE), a... 
histamine H3 receptor | LIPID-PEROXIDATION | ADULT RATS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTICONVULSANT | antagonist | ASCORBIC-ACID | CHEMISTRY, MULTIDISCIPLINARY | H-3 | pilocarpine | HIPPOCAMPUS | status epilepticus | neuroprotection | ANTIOXIDANT | AMYGDALOID-KINDLED SEIZURES | rats | EPILEPSY | oxidative stress
Journal Article
Neuropharmacology, ISSN 0028-3908, 07/2016, Volume 106, pp. 46 - 55
Journal Article
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, ISSN 0091-6749, 02/2012, Volume 129, Issue 2, pp. 409 - U204
Background: Nasal H-3 receptors might have a role in mediating the effects of histamine in patients with allergic rhinitis. Objective: This study explored the... 
NASAL | ACTIVATION | ALLERGY | H-3 receptor antagonist | nasal congestion | allergic rhinitis | IMMUNOLOGY | decongestant
Journal Article
Clinical Neuropharmacology, ISSN 0362-5664, 01/2014, Volume 37, Issue 1, pp. 26 - 30
Journal Article
BEHAVIOURAL BRAIN RESEARCH, ISSN 0166-4328, 05/2016, Volume 305, pp. 100 - 107
Ethanol abuse potential is mainly due to its reinforcing properties, crucial in the transition from the recreational to pathological use. These properties are... 
Conessine | FUNCTIONAL POLYMORPHISM | Conditioned place preference | NOREPINEPHRINE | PLACE PREFERENCE | H3 RECEPTOR | HISTAMINE N-METHYLTRANSFERASE | ALCOHOL-CONSUMPTION | Monoamines | NEUROSCIENCES | PREFRONTAL CORTEX | INDUCED REWARD | INVERSE AGONIST THIOPERAMIDE | H-3 receptor antagonist | DOPAMINE | BEHAVIORAL SCIENCES | Psychostimulation | Alcohol addiction
Journal Article
PHARMACOLOGY & THERAPEUTICS, ISSN 0163-7258, 08/2019, Volume 200, pp. 69 - 84
Since the discovery of the histamine H-3 receptor in 1983, tremendous advances in the pharmacological aspects of H-3 receptor antagonists/inverse agonists have... 
ALZHEIMERS-DISEASE | Clinical trials | H3 INVERSE AGONIST | COGNITIVE IMPAIRMENT | ANTAGONIST/INVERSE AGONIST | Pitolisant | H-3-RECEPTOR ANTAGONIST | INTERNATIONAL-LEAGUE | S 38093 | THERAPEUTIC DRUG TARGET | H-3 antagonists | H-3 inverse agonists | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | Histamine H-3 receptor | Neurological disorders | PROCOGNITIVE PROPERTIES
Journal Article
Journal Article
CURRENT ALZHEIMER RESEARCH, ISSN 1567-2050, 01/2014, Volume 11, Issue 1, pp. 47 - 58
Introduction: Histaminergic H-3 receptors may play a role in modulating cholinergic and monoaminergic neurotransmission. This Phase II study evaluated the... 
histamine | LIFE-STYLE AIBL | COGNITIVE PERFORMANCE | DEMENTIA | cognition | ACETYLCHOLINE | BRAIN HISTAMINE | RELEASE | NEUROSCIENCES | HISTAMINE-RECEPTOR | CLINICAL NEUROLOGY | episodic memory | H-3 receptor antagonist | CLINICAL-TRIALS | INVERSE AGONIST | attention | SCALE | Alzheimer's disease | executive function
Journal Article
Neuropharmacology, ISSN 0028-3908, 07/2016, Volume 106, pp. 156 - 163
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 12/2012, Volume 167, Issue 7, pp. 1398 - 1414
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2019, Volume 62, Issue 9, pp. 4638 - 4655
The histamine 3 receptor (H3R) is a presynaptic receptor, which modulates several neurotransmitters including histamine and various essential physiological... 
H-3 RECEPTOR | SYSTEM | TARGET | CHEMISTRY, MEDICINAL | PROTEIN | NEURONAL HISTAMINE | H3 RECEPTOR | 2-AMINOPYRIMIDINES | IDENTIFICATION | DISCOVERY | AGONIST
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2010, Volume 335, Issue 3, pp. 636 - 644
Journal Article
PSYCHOPHARMACOLOGY, ISSN 0033-3158, 07/2013, Volume 228, Issue 1, pp. 85 - 95
Growing evidence supports a role for the central histaminergic system to have a modulatory influence on drug addiction in general and alcohol-use disorders in... 
METHAMPHETAMINE | Conditioned place preference | Ethanol | RAT | ST1283 | DRINKING | PSYCHIATRY | Two-bottle choice | BRAIN HISTAMINE | THIOPERAMIDE | H3 RECEPTOR | Alcohol | CONSTITUTIVE ACTIVITY | NEUROSCIENCES | R-(alpha)-methyl-Histamine (RAMH) | NUCLEUS-ACCUMBENS | Histamine | DOPAMINE | PHARMACOLOGY & PHARMACY | Histamine H-3 receptor | INDUCED ANTINOCICEPTION
Journal Article
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, ISSN 0028-1298, 08/2019, Volume 392, Issue 8, pp. 925 - 936
We previously reported that hypothalamic tumor necrosis factor-alpha (TNF-alpha) mRNA expression via histamine H-4 receptors contributes to the development of... 
Anorexia | FOOD-INTAKE | Orexin OX2 receptor | CONSTITUTIVE ACTIVITY | SYMPTOMS | Cisplatin | Histamine H-4 receptor | CANCER-PATIENTS | NEURONS | PHARMACOLOGY & PHARMACY | Mice | Histamine H-3 receptor | NONPEPTIDE | BRAIN
Journal Article