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1998, 1st ed., Pharmacochemistry library, ISBN 0444829369, Volume 30, 304
In the early eighties when the H3 receptor was identified, many thought that an H3 ligand, an agonist or an antagonist, would become available as a therapeutic... 
Histamine | Receptors | Neurotransmitter receptors | Histamine - Receptors
eBook
Synapse, ISSN 0887-4476, 07/2019, Volume 73, Issue 7, pp. e22096 - n/a
Journal Article
Neuropharmacology, ISSN 0028-3908, 01/2019, Volume 144, pp. 244 - 255
The histamine H receptor is a G protein-coupled receptor (GPCR) drug target that is highly expressed in the CNS, where it acts as both an auto- and... 
Kinetics | S 38093-2 | Sigma-1 receptor | Receptor occupancy | Histamine H3 receptor
Journal Article
Translational Research, ISSN 1931-5244, 2015, Volume 165, Issue 4, pp. 512 - 530
Renal fibrosis is the hallmark of virtually all progressive kidney diseases and strongly correlates with the deterioration of kidney function. The... 
Internal Medicine | activating transcription factor 2 | inhibitor of kappa B | activator protein-1 | unilateral ureteral obstruction | AP-1 | CTGF | ANG II | TGF-β-inducible gene | TβRII | angiotensin-converting enzyme | bone morphogenetic protein receptor | Monocyte chemoattractant protein-1 | idiopathic pulmonary fibrosis | PPARγ | ARB | plasminogen activator inhibitor-1 | TAK1-binding protein 1 | receptor-regulated Smads | angiotensin II receptor blocker | MAPK kinase kinase kinase | stz | CCL2-CCR2 | uterine sensitization-associated gene-1 | ESRD | chronic kidney disease | TSP 1 | nuclear factor kappa B | acute tubular necrosis | mitogen-activated protein kinase | Peroxisome proliferator-activated receptor γ | TrKA | A Study of Cardiovascular Events in Diabetes | TAK1 | USAG-1 | ASCEND | transforming growth factor β1 | von Willebrand factor | βig-h3 | FSGS | MKKK | heparan sulfate proteoglycan | CCR1 | ACE | HSPG | BMP | MKK | bone morphogenetic protein | ECM | endothelin | thrombospondin type 1 | tyrosine receptor kinase A | ETA | focal segmental glomerular sclerosis | ATN | phosphodiesterase | TAB1 | ATF 2 | extracellular matrix | Kielin/chordin-like protein | JNK | RAAS | small interfering RNA | LRP | lipoprotein receptor-related protein | NF-κB | renin-angiotensin-aldosterone system | BMPR | PAI-1 | LC3 | TGF-β type I receptor | c-Jun N-terminal kinase | TβRI | IGF-1 | end-stage renal disease | MAPK | EMT | UUO | epithelial-to-mesenchymal transition | connective tissue growth factor | streptozotocin | Nox | ROS | mitogen-activated protein kinase kinase | insulin-like growth factor 1 | nicotinamide adenine dinucleotide phosphate oxidase | MCP-1 | tumor necrosis factor α | estimated glomerular filtration rate | vWF | CC motif chemokine ligand 2-CC receptor type 2 | TGF-β type II receptor | IκB | microtubule-associated protein 1 light chain 3 | PDE | TGF-β-activated kinase 1 | reactive oxygen species | CC receptor type 1 | Angiotensin II | CKD | endothelin A receptor | eGFR | VEGF | siRNA | TNF-α | R-Smads | vascular endothelial growth factor | KCP | TGF-β1 | IPF | MEDICINE, RESEARCH & EXPERIMENTAL | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | ANGIOTENSIN-ALDOSTERONE SYSTEM | DIABETIC-NEPHROPATHY | MATRIX GENE-EXPRESSION | RENAL FIBROSIS | MEDICINE, GENERAL & INTERNAL | TISSUE GROWTH-FACTOR | TRANSFORMING GROWTH-FACTOR-BETA-1 | BONE MORPHOGENETIC PROTEIN-7 | TGF-BETA ANTIBODY | MEDICAL LABORATORY TECHNOLOGY | IDIOPATHIC PULMONARY-FIBROSIS | Fibrosis - drug therapy | Signal Transduction | Humans | Transforming Growth Factor beta1 - metabolism | Drug Design | Transforming Growth Factor beta1 - genetics | Fibrosis - pathology | Renal Insufficiency, Chronic - drug therapy | Renal Insufficiency, Chronic - pathology | Oxidases | Phosphates | Niacinamide | Medical colleges | Development and progression | Transforming growth factors | Homeopathy | Materia medica and therapeutics | Purines | Chronic kidney failure | Nitric oxide | Therapeutics | Angiotensin | Bone morphogenetic proteins | Health aspects | bone morphogenic protein-7 | autophagy | transforming growth factor-β | NADPH oxidase | tumor necrosis factor-α | Kidney fibrosis | endothelin-1 | C-C motif chemokine | chemokine receptor
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