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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 48, pp. 14960 - 14965
Journal Article
FEBS Letters, ISSN 0014-5793, 05/2019, Volume 593, Issue 10, pp. 1061 - 1071
Homocysteine (Hcy) is associated with nonalcoholic fatty liver disease (NAFLD). orphan nuclear receptor subfamily 4 group A member 1 (NR4A1) is involved in... 
homocysteine | NR4A1 | nonalcoholic fatty liver disease | histone H3K27 acetylation | steatosis
Journal Article
Fungal Genetics and Biology, ISSN 1087-1845, 11/2019, Volume 132, p. 103256
Many secondary metabolites are produced by biosynthetic gene clusters (BGCs) that are repressed during standard growth conditions, which complicates the... 
Fungi | Histone methyltransferase | Metabolomics | Secondary metabolites | H3K27
Journal Article
Developmental Cell, ISSN 1534-5807, 01/2012, Volume 22, Issue 1, pp. 25 - 37
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 10/2015, Volume 67, pp. 148 - 157
Gene expression is epigenetically regulated through DNA methylation and covalent chromatin modifications, such as acetylation, phosphorylation, ubiquitination,... 
Jumonji | Utx | Jmjd3 | H3K27 | Histone demethylation | ENDODERM DIFFERENTIATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HISTONE DEMETHYLASE JMJD3 | MYELODYSPLASTIC SYNDROME | CELLULAR SENESCENCE | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | DOMAIN-CONTAINING PROTEINS | H3K27 DEMETHYLASE | GENE-EXPRESSION | ARGININE METHYLATION | MACROPHAGE POLARIZATION | Chromatin - metabolism | Polycomb Repressive Complex 2 - genetics | Epigenesis, Genetic | Humans | Jumonji Domain-Containing Histone Demethylases - immunology | Neurodegenerative Diseases - immunology | Histone Demethylases - genetics | Neoplasms - genetics | Gene Expression Regulation, Developmental | Polycomb Repressive Complex 2 - immunology | Lysine - metabolism | Germ Layers - growth & development | Germ Layers - cytology | Nuclear Proteins - genetics | Chromatin - chemistry | Neurodegenerative Diseases - pathology | Germ Layers - metabolism | Histone Demethylases - immunology | Neurodegenerative Diseases - genetics | Immunity, Innate | Nuclear Proteins - immunology | Jumonji Domain-Containing Histone Demethylases - genetics | Enhancer of Zeste Homolog 2 Protein | Animals | Histones - genetics | Neoplasms - immunology | Mice | Histones - metabolism | Neoplasms - pathology | Ubiquitin | Epigenetic inheritance | Nervous system diseases | Transferases | Histones | Methylation | Gene expression
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 10/2016, Volume 23, Issue 32, pp. 3687 - 3696
Journal Article
Cell, ISSN 0092-8674, 09/2018, Volume 175, Issue 1, pp. 186 - 199.e19
Mutations or aberrant upregulation of EZH2 occur frequently in human cancers, yet clinical benefits of EZH2 inhibitor (EZH2i) remain unsatisfactory and limited... 
MLL1 | acetylation | crosstalk | methylation | therapy | cancer | histone | H3K27 | MAPK | EZH2 | STEM-CELLS | EZH2 INHIBITION | ERK1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | H3K27 ACETYLATION | TRANSCRIPTIONAL REGULATION | CANCER | EXPRESSION | NERVE SHEATH TUMORS | SOMATIC MUTATIONS | REVEALS | CELL BIOLOGY | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | p300-CBP Transcription Factors - physiology | Humans | Transcriptional Activation | Male | MAP Kinase Signaling System | Epigenomics - methods | Histone Code - drug effects | Myeloid-Lymphoid Leukemia Protein - physiology | Female | Gene Expression Regulation, Neoplastic - genetics | Enhancer of Zeste Homolog 2 Protein - genetics | Histone-Lysine N-Methyltransferase - genetics | Transcription Factors - physiology | Carcinogenesis - genetics | Nuclear Proteins - metabolism | Mice, SCID | Xenograft Model Antitumor Assays - methods | Transcription Factors - metabolism | Animals | Histones - genetics | Epigenesis, Genetic - genetics | Myeloid-Lymphoid Leukemia Protein - genetics | Histones - physiology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Nuclear Proteins - physiology | Mutation | Polycomb Repressive Complex 2 - metabolism | Histone Code - genetics | Histone-Lysine N-Methyltransferase - physiology | Epigenetic inheritance | Methylation | Health aspects | Analysis | Cancer | Index Medicus
Journal Article
Anticancer Research, ISSN 0250-7005, 08/2018, Volume 38, Issue 8, pp. 4535 - 4542
Background: Chemoresistance of cancer stem cells (CSCs) is considered a major cause of post-treatment recurrence that negatively impacts the prognosis of... 
Drug repositioning | Repurposing | Drug resistance | Apoptosis | H3K27 DEMETHYLASE INHIBITOR | ONCOLOGY | GSKJ4 | apoptosis | repurposing | drug resistance | DRUG-RESISTANCE | SIRNA
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2019, Volume 47, Issue D1, pp. D874 - D880
Abstract Protein post-translational modifications (PTMs), including phosphorylation, ubiquitination, methylation, acetylation, glycosylation et al, are very... 
VARIANTS | H3K27 METHYLATION | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTATIONS | ASSOCIATION | PHOSPHORYLATION SITE | PREDICTION | TOOL | Database Issue
Journal Article
Developmental Biology, ISSN 0012-1606, 06/2019, Volume 450, Issue 1, pp. 34 - 46
Many organisms both undergo dramatic morphological changes during post-embryonic development and also regenerate lost structures, but the roles of epigenetic... 
Homeotic transformation | Enhancer of zeste (E(z)) | Epigenetics | Polycomb | Tribolium castaneum | Polycomb group (PcG) proteins | H3K27 | Limb regeneration | Metamorphosis
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 2014, Volume 13, Issue 4, pp. 842 - 854
Journal Article
Nature, ISSN 0028-0836, 08/2011, Volume 476, Issue 7360, pp. 298 - 303
Journal Article