X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (243) 243
humans (152) 152
methylation (141) 141
animals (114) 114
histones - metabolism (99) 99
h3k27 (96) 96
cancer (93) 93
biochemistry & molecular biology (86) 86
h3k27 methylation (85) 85
cell biology (83) 83
ezh2 (82) 82
epigenetics (80) 80
gene expression (77) 77
dna methylation (70) 70
chromatin (69) 69
oncology (66) 66
mice (65) 65
gene-expression (58) 58
lysine (54) 54
macromolecular substances (50) 50
expression (48) 48
histones (48) 48
proteins (48) 48
male (47) 47
article (46) 46
female (46) 46
epigenesis, genetic (45) 45
genetic aspects (45) 45
mutation (44) 44
genetics & heredity (43) 43
research (42) 42
jmjd3 (41) 41
h3k27 demethylase (40) 40
analysis (39) 39
histone h3 (39) 39
enhancer of zeste homolog 2 protein (37) 37
differentiation (36) 36
epigenetic inheritance (36) 36
polycomb (36) 36
transcription (36) 36
genes (35) 35
jumonji domain-containing histone demethylases - metabolism (34) 34
stem cells (34) 34
cell line, tumor (33) 33
embryonic stem-cells (33) 33
h3k27 demethylases (32) 32
histones - genetics (31) 31
jumonji domain-containing histone demethylases - genetics (30) 30
lysine - metabolism (30) 30
prc2 (29) 29
acetylation (28) 28
biology (28) 28
developmental biology (28) 28
polycomb repressive complex 2 - metabolism (28) 28
cell differentiation (26) 26
cells (26) 26
health aspects (26) 26
polycomb repressive complex 2 - genetics (26) 26
utx (26) 26
methyltransferase (25) 25
somatic mutations (25) 25
chromatin immunoprecipitation (23) 23
epigenetic regulation (23) 23
cell proliferation (22) 22
gene expression regulation, developmental (22) 22
histone methylation (22) 22
histone methyltransferase (22) 22
multidisciplinary sciences (22) 22
promoter regions, genetic (22) 22
stem-cells (22) 22
gene silencing (21) 21
histone (21) 21
mutations (21) 21
polycomb group proteins (21) 21
aged (20) 20
apoptosis (20) 20
binding (20) 20
gene (20) 20
gene expression regulation, neoplastic (20) 20
genetics (20) 20
middle aged (20) 20
prognosis (20) 20
transcription factors - metabolism (20) 20
development and progression (19) 19
genomes (19) 19
group protein ezh2 (19) 19
immunohistochemistry (19) 19
proliferation (19) 19
protein binding (19) 19
breast cancer (18) 18
cells, cultured (18) 18
chromatin - metabolism (18) 18
deoxyribonucleic acid--dna (18) 18
inhibition (18) 18
methyltransferases (18) 18
b-cell lymphomas (17) 17
breast-cancer (17) 17
cell line (17) 17
dna (17) 17
h3k27 trimethylation (17) 17
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Molecular Therapy - Nucleic Acids, ISSN 2162-2531, 12/2019, Volume 18, pp. 285 - 297
Ischemia-reperfusion injury is a common early complication after lung transplantation. It was reported that long non-coding RNA (lncRNA) metastasis-associated... 
p300 | metastasis-associated lung adenocarcinoma transcript 1 | pulmonary epithelial cells | inflammatory injury | lung transplant ischemia-reperfusion | long non-coding RNA | interleukin-8 | H3K27 acetylation | chemotaxis of neutrophils
Journal Article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, ISSN 1756-9966, 01/2019, Volume 38, Issue 1, pp. 21 - 12
Telomeres, the nucleoprotein structures that cap the ends of eukaryotic chromosomes, play important and multiple roles in tumorigenesis. Functional telomeres... 
Sirtuins | PEDIATRIC HIGH-GRADE | Chromatin | H3K27 METHYLATION | HISTONE VARIANT H3.3 | ALT | REPEAT BINDING-FACTORS | Telomere | Heterochromatin | GENOMIC STABILITY | ONCOLOGY | CONTAINING RNA | Epigenetics | GENE-EXPRESSION | INTRINSIC PONTINE GLIOMAS | MOLECULAR-BASIS | DRIVER MUTATIONS | Cancer | Epigenetic inheritance | Telomeres | Cell death | DNA damage | Development and progression | DNA repair | Yeast | Chromosomes | Apoptosis
Journal Article
Cell Reports, ISSN 2211-1247, 11/2019, Volume 29, Issue 7, pp. 1800 - 1811.e6
Pluripotent embryonic stem cells (ESCs) constitute an essential cellular niche sustained by epigenomic and transcriptional regulation. Any role of... 
H3K27 methylation | RNA exosome | nuclear RNA decay | PRC2 | PAXT | chromatin | stem cell regulation
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2019, Volume 76, Issue 3, pp. 423 - 436.e3
The Polycomb repressive complex 2 (PRC2) catalyzes H3K27 methylation across the genome, which impacts transcriptional regulation and is critical for... 
H3K27 methylation | PRC2 | transcription | PRC1 | polycomb | epigenetics | EZH2 | H3K27me3
Journal Article
Fungal Genetics and Biology, ISSN 1087-1845, 11/2019, Volume 132, p. 103256
Many secondary metabolites are produced by biosynthetic gene clusters (BGCs) that are repressed during standard growth conditions, which complicates the... 
Fungi | Histone methyltransferase | Metabolomics | Secondary metabolites | H3K27
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 10/2019, Volume 118, p. 109384
Currently, stem cells are reported to be involved in tumor formation, drug resistance and recurrence. Inhibiting the proliferation of tumor cells, promoting... 
JMJD3 | H3K27 | Embryonic stem cells | Histone demethylation | Cancer | TRANSCRIPTION FACTORS | KDM6B | MEDICINE, RESEARCH & EXPERIMENTAL | OSTEOBLAST DIFFERENTIATION | H3K27ME3 DEMETHYLASE | DOWN-REGULATION | OSTEOGENIC DIFFERENTIATION | OVARIAN-CANCER | MEDIATED REPRESSION | HISTONE DEMETHYLASE | EPIGENETIC REGULATION | PHARMACOLOGY & PHARMACY
Journal Article
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, ISSN 0147-5185, 10/2019, Volume 43, Issue 10, pp. 1323 - 1330
Spindle cell rhabdomyosarcoma (RMS) is an aggressive sarcoma type with a predilection for the head and neck and frequent transactivating MYOD1 mutations.... 
H3K27 TRIMETHYLATION LOSS | SUZ12 | SURGERY | DIAGNOSIS | METHYLATION | malignant peripheral nerve sheath tumor | PRC2 | MARKER | immunohistochemistry | MUTATIONS | PATHOLOGY | spindle cell rhabdomyosarcoma | Diagnosis, Differential | Nervous system tumors | Rhabdomyosarcoma | Physiological aspects | Genetic aspects | Diagnosis | Peripheral nerve diseases | Methods
Journal Article
GENES, ISSN 2073-4425, 09/2019, Volume 10, Issue 9, p. 695
Histone methylation patterns are important epigenetic regulators of mammalian development, notably through stem cell identity maintenance by chromatin... 
HOX | methylstat | DNA METHYLATION | embryos | GAMETOGENESIS | GENETICS & HEREDITY | histone modifications | DEMETHYLASES | epigenetics | mollusk | ORTHOLOGUES | H3K4 | H3K9 | H3K27 | H3K36
Journal Article
Neuropeptides, ISSN 0143-4179, 08/2019, Volume 76, p. 101929
Lysine methylation is an important dynamic modification which is essential in the epigenetic regulation of gene transcription. Unlike acetylation markers,... 
Histone modification | Lysine methylation | Lysine methyltransferase | Nervous system disease | Lysine demethylase | EPIGENETIC MECHANISMS | METHYLTRANSFERASE | H3K27 METHYLATION | HISTONE METHYLATION | SYNAPTIC PLASTICITY | NEUROSCIENCES | HIPPOCAMPUS | MEMORY | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | MUTATIONS | PROTEOMIC ANALYSIS
Journal Article
JOURNAL OF BIOCHEMISTRY, ISSN 0021-924X, 07/2019, Volume 166, Issue 1, pp. 41 - 50
Dysregulation of enhancer of zeste homologue 2 (EZH2), a methyltransferase component of polycomb repressive complex 2, is found in many types of cancers... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | high-throughput screening | histone H3 lysine 27 trimethylation | H3K27 | EZH2 inhibitor | CANCER | anti-tumour agent | LYSINE 27 | drug discovery | PRC2 | MUTATION | HISTONE METHYLTRANSFERASE EZH2 | HYPERTRIMETHYLATION | INHIBITOR | PROMOTER
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 07/2019, Volume 23, Issue 7, pp. 4770 - 4778
Thyroid carcinoma is the most common endocrine malignancy. Surgery, post‐operative selective iodine‐131 and thyroid hormone suppression were the most common... 
thyroid carcinoma | H3K27 | miR‐124/506 | Sorafenib | EZH2 | UNITED-STATES | MEDICINE, RESEARCH & EXPERIMENTAL | PROLIFERATION | CANCER | POLYCOMB | CELL BIOLOGY | GROWTH | LATERAL NECK DISSECTION | OUTCOMES | miR-124/506 | Carcinoma | Vascular endothelial growth factor | Health aspects | Thyroid diseases | Cancer | miR‐124 | 506 | Original
Journal Article