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Nature, ISSN 0028-0836, 06/2012, Volume 486, Issue 7403, pp. 420 - 428
Highly pathogenic avian H5N1 influenza A viruses occasionally infect humans, but currently do not transmit efficiently among humans. The viral haemagglutinin... 
SINGLE AMINO-ACID | MEMBRANE-FUSION | IN-VITRO | AVIAN H5N1 | HEMAGGLUTININ | A VIRUSES | MULTIDISCIPLINARY SCIENCES | SIALIC-ACID | RECEPTOR-BINDING SPECIFICITY | MOLECULAR-BASIS | SWINE-ORIGIN H1N1 | Pandemics | Reassortant Viruses - pathogenicity | Influenza A Virus, H5N1 Subtype - physiology | Receptors, Virus - metabolism | Humans | Influenza A Virus, H1N1 Subtype - physiology | Reassortant Viruses - genetics | Reassortant Viruses - physiology | Influenza A Virus, H5N1 Subtype - genetics | Body Fluids - virology | Molecular Epidemiology - methods | Ferrets - virology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Zoonoses - virology | Respiratory System - virology | Adaptation, Physiological - genetics | HEK293 Cells | Female | Influenza, Human - virology | Protein Stability | Influenza A Virus, H1N1 Subtype - genetics | Population Surveillance - methods | Cell Line | Security Measures | Birds - virology | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza in Birds - transmission | Hot Temperature | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Reassortant Viruses - isolation & purification | Respiratory System - anatomy & histology | Zoonoses - transmission | Animals | Receptors, Virus - chemistry | Orthomyxoviridae Infections - transmission | Dogs | Influenza in Birds - virology | Bioterrorism - prevention & control | Influenza A Virus, H5N1 Subtype - pathogenicity | HeLa Cells | Influenza, Human - prevention & control | Orthomyxoviridae Infections - virology | Evolution, Molecular | Prevention | Epidemics | Disease transmission | United States | Japan | Avian influenza viruses | Physiological aspects | Genetic aspects | Research | Host-virus relationships | Ferrets | Cell culture | Task forces | Compliance | Laboratories | RNA polymerase | Academic libraries | Experiments | Avian flu | Proteins | Studies | Swine flu | Plasmids | Risk assessment | Occupational health | Mutation
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 22, pp. 8107 - 8112
The source, timing, and geographical origin of the 1918–1920 pandemic influenza A virus have remained tenaciously obscure for nearly a century, as have the... 
H1N1 subtype influenza A virus | Pandemics | Influenza A virus | Swine | Mortality | Childhood | Antibodies | Viruses | Immunity | Age groups | Pathogenicity | Cohort immunity | Phylogeny | Reassortment | Virulence | UNITED-STATES | MORTALITY | reassortment | ORIGINAL ANTIGENIC SIN | NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | HUMAN SERA | PATTERNS | cohort immunity | pathogenicity | RESPONSES | DIFFERENT AGES | virulence | phylogeny | INFECTION | EPIDEMIOLOGY | Influenza A Virus, H1N1 Subtype - immunology | Reassortant Viruses - pathogenicity | Humans | Influenza A virus - genetics | Reassortant Viruses - genetics | Disease Resistance - immunology | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - genetics | Influenza A Virus, H3N8 Subtype - genetics | Influenza A Virus, H3N8 Subtype - pathogenicity | Influenza A Virus, H7N9 Subtype - immunology | Genetic Variation | Reassortant Viruses - immunology | Influenza A Virus, H7N9 Subtype - pathogenicity | Influenza A virus - pathogenicity | Influenza, Human - mortality | Adult | Influenza A virus - immunology | Influenza, Human - virology | Child | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - pathogenicity | Influenza Pandemic, 1918-1919 - mortality | Birds | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza A Virus, H3N2 Subtype - immunology | Biological Evolution | Animals | Influenza A Virus, H3N8 Subtype - immunology | Influenza A Virus, H5N1 Subtype - immunology | Influenza A Virus, H5N1 Subtype - pathogenicity | Aged | Influenza A Virus, H7N9 Subtype - genetics | Causes of | Epidemics | United States | Swine influenza | Biological Sciences
Journal Article
Science, ISSN 0036-8075, 6/2012, Volume 336, Issue 6088, pp. 1534 - 1541
Highly pathogenic avian influenza A/H5N1 virus can cause morbidity and mortality in humans but thus far has not acquired the ability to be transmitted by... 
Receptors | Inoculation | Experimental infection | Disease transmission | Pandemics | REPORTS | Viruses | Orthomyxoviridae | Ferrets | Genetic mutation | Amino acid substitution | A VIRUS | TO-PERSON TRANSMISSION | MEDIATED SELECTION | H5N1 VIRUS | HEMAGGLUTININ | MULTIDISCIPLINARY SCIENCES | HOST | INFECTION | MODEL | RECEPTOR SPECIFICITY | PATHOGENIC AVIAN INFLUENZA | Immune Sera | Reassortant Viruses - pathogenicity | Influenza A Virus, H5N1 Subtype - physiology | Poultry | Receptors, Virus - metabolism | Air Microbiology | Humans | Virulence | Molecular Sequence Data | Influenza A Virus, H5N1 Subtype - genetics | Virus Shedding | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Respiratory System - virology | Female | Influenza, Human - virology | Oseltamivir - pharmacology | Disease Models, Animal | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Reverse Genetics | Antiviral Agents - pharmacology | Mutagenesis, Site-Directed | RNA Replicase - genetics | Viral Proteins - chemistry | Sialic Acids - metabolism | Viral Proteins - genetics | Influenza, Human - epidemiology | Containment of Biohazards | Influenza A Virus, H5N1 Subtype - drug effects | Influenza in Birds - epidemiology | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | RNA Replicase - chemistry | Influenza in Birds - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | Mutation | Serial Passage | Orthomyxoviridae Infections - virology | Amino Acid Substitution | Avian influenza | Diseases and pests | Physiological aspects | Development and progression | Research | Animal diseases | Amino acids | Avian flu | Small mammals | Index Medicus | Polymerase | Human | Proteins | Influenza | Droplets | Genetic modification
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 12/2016, Volume 20, Issue 6, pp. 810 - 821
Constant surveillance of live poultry markets (LPMs) is currently the best way to predict and identify emerging avian influenza viruses (AIVs) that pose a... 
genesis | prevalence | live poultry markets | H5N6 avian influenza | resassortment | evolution | birds | human infection | HUMAN INFECTION | H7N9 VIRUS | MICROBIOLOGY | SHORT READ ALIGNMENT | HONG-KONG | ORIGIN | LIVE POULTRY MARKETS | VIROLOGY | H9N2 | A(H5N6) VIRUS | A VIRUSES | MIGRATORY BIRDS | PARASITOLOGY | Public Health | Prevalence | Humans | Chickens - virology | Geographic Mapping | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H9N2 Subtype - pathogenicity | Phylogeny | RNA, Viral - genetics | Genes, Viral - genetics | Poultry - virology | Base Sequence | Influenza A Virus, H7N9 Subtype - pathogenicity | Hemagglutinins | Influenza, Human - virology | Agriculture | Genome, Viral | Influenza A Virus, H5N8 Subtype - pathogenicity | Influenza A Virus, H9N2 Subtype - genetics | Influenza A Virus, H5N8 Subtype - classification | Ducks - virology | Columbidae - virology | Genotype | Influenza, Human - epidemiology | Geese - virology | Influenza in Birds - epidemiology | China - epidemiology | Animals | Epidemiological Monitoring | Influenza in Birds - virology | Neuraminidase | Reassortant Viruses | Influenza A Virus, H5N1 Subtype - pathogenicity | Influenza A Virus, H5N8 Subtype - genetics | Influenza A Virus, H7N9 Subtype - genetics | Cities | Influenza A Virus, H5N8 Subtype - isolation & purification | Evolution, Molecular | Virus diseases | Avian influenza | Cladistic analysis | Analysis | Lectins | Avian influenza viruses | Health aspects
Journal Article
Vaccine, ISSN 0264-410X, 2017, Volume 35, Issue 8, pp. 1104 - 1109
Journal Article
Virology, ISSN 0042-6822, 2007, Volume 362, Issue 2, pp. 271 - 282
Abstract The transcription/replication activity of ribonucleoproteins derived from influenza A primary isolates of human (A/Paris/908/97) or avian origin... 
Infectious Disease | PB2 | Transcription/replication | Influenza A virus | Host-range | host-range | RNA REPLICATION | REASSORTANT VIRUSES | transcription/replication | AMINO-ACID | HIGH VIRULENCE | VIROLOGY | GENES | H5N1 VIRUSES | RECEPTOR SPECIFICITY | REVERSE GENETICS | MOLECULAR-BASIS | BINDING | influenza A virus | Influenza A Virus, H5N1 Subtype - physiology | Humans | Influenza A virus - genetics | Influenza A Virus, H1N1 Subtype - physiology | Cercopithecus aethiops | Molecular Sequence Data | Chloramphenicol O-Acetyltransferase - genetics | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - genetics | Viral Proteins - metabolism | Transcription, Genetic | Influenza A Virus, H1N1 Subtype - genetics | Genes, Reporter | Cell Line | Chloramphenicol O-Acetyltransferase - analysis | Influenza A virus - physiology | Promoter Regions, Genetic | RNA, Viral - biosynthesis | Viral Plaque Assay | Viral Proteins - genetics | Ribonucleoproteins - metabolism | Sequence Analysis, DNA | Protein Interaction Mapping | Animals | Virus Replication | Chickens | RNA Polymerase I | Influenza A Virus, H3N2 Subtype - physiology | COS Cells | Proteins | Control | Influenza | Influenza A Virus, H3N2 Subtype | Influenza A Virus, H5N1 Subtype | Viral Proteins | Life Sciences | Influenza A Virus, H1N1 Subtype | Promoter Regions (Genetics) | Ribonucleoproteins | Chloramphenicol O-Acetyltransferase | Virology | Microbiology and Parasitology | RNA, Viral | Plaque Assay
Journal Article
Journal Article
Virology, ISSN 0042-6822, 2011, Volume 422, Issue 1, pp. 105 - 113
Journal Article
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7584, pp. 101 - 104
Influenza pandemics occur unpredictably when zoonotic influenza viruses with novel antigenicity acquire the ability to transmit amongst humans(1). Host range... 
PB2 | REPLICATION | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | REVERSE GENETICS SYSTEM | ADAPTATION | RIBONUCLEOPROTEINS | GENERATION | RNA-POLYMERASE | SUBUNIT | RANGE | Influenza A Virus, H5N1 Subtype - enzymology | Influenza A Virus, H7N9 Subtype - physiology | Cricetulus | Species Specificity | Influenza A Virus, H5N1 Subtype - physiology | Humans | Influenza A virus - genetics | RNA Replicase - metabolism | Chickens - virology | Influenza A Virus, H5N1 Subtype - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Viral Proteins - metabolism | Avian Proteins - chemistry | Gene Knockdown Techniques | Intracellular Signaling Peptides and Proteins - deficiency | Transcription, Genetic | Influenza A Virus, H7N9 Subtype - enzymology | Amino Acid Sequence | Cell Line | Influenza A virus - physiology | Avian Proteins - metabolism | Cricetinae | RNA Replicase - genetics | Viral Proteins - genetics | Host Specificity | Influenza A virus - enzymology | Animals | Virus Replication | Avian Proteins - deficiency | Gene Expression Regulation, Viral | Intracellular Signaling Peptides and Proteins - chemistry | Dogs | Influenza A Virus, H7N9 Subtype - genetics | Evolution, Molecular | Avian influenza | Antiviral agents | Complications and side effects | Care and treatment | Research | Health aspects | Proteins | Pandemics | Genes | Viruses | Principal components analysis | Genomes | Mutation | RNA polymerase | Mammals | Avian flu
Journal Article
Clinical Chemistry, ISSN 0009-9147, 08/2009, Volume 55, Issue 8, pp. 1555 - 1558
BACKGROUND: Influenza A viruses are medically important viral pathogens that cause significant mortality and morbidity throughout the world. The recent... 
MEDICAL LABORATORY TECHNOLOGY | Influenza A Virus, H2N2 Subtype - isolation & purification | Molecular Diagnostic Techniques - methods | Influenza A Virus, H1N1 Subtype - classification | Humans | DNA, Viral - analysis | Influenza A Virus, H5N1 Subtype - classification | Influenza A Virus, H5N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - genetics | Molecular Diagnostic Techniques - economics | Influenza A Virus, H5N1 Subtype - isolation & purification | Reverse Transcriptase Polymerase Chain Reaction - economics | RNA, Viral - genetics | Influenza A Virus, H1N1 Subtype - isolation & purification | Influenza A Virus, H3N2 Subtype - isolation & purification | Time Factors | Base Sequence | Reverse Transcriptase Polymerase Chain Reaction - methods | Sensitivity and Specificity | Influenza, Human - diagnosis | Influenza, Human - virology | RNA, Viral - isolation & purification | Influenza A Virus, H1N1 Subtype - genetics | Influenza A Virus, H3N2 Subtype - classification | RNA, Viral - analysis | Influenza A Virus, H2N2 Subtype - classification | Orthomyxoviridae Infections - diagnosis | Animals | Influenza A Virus, H2N2 Subtype - genetics | DNA, Viral - genetics | Orthomyxoviridae Infections - virology | Swine - virology | Influenza viruses | Polymerase chain reaction | Usage | Swine influenza | Causes of | Genetic aspects | Research | Diagnosis | Health aspects | Viruses | Mathematical models | Microbiology | Swine flu | Laboratories | Influenza A Virus, H3N2 Subtype | Influenza A Virus, H2N2 Subtype | Influenza A Virus, H5N1 Subtype | Reverse Transcriptase Polymerase Chain Reaction | Virology | Life Sciences | Microbiology and Parasitology | Molecular Diagnostic Techniques | Swine | RNA, Viral | Influenza, Human | Influenza A Virus, H1N1 Subtype | Orthomyxoviridae Infections | DNA, Viral
Journal Article