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Journal of Thoracic Oncology, ISSN 1556-0864, 03/2012, Volume 7, Issue 3, pp. 574 - 578
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 09/2019, Volume 60, Issue 37, p. 150915
[Display omitted] •Synthesized precise C1–C11 eribulin fragment from l-ascorbic acid.•Synthesized two diastereomeric analogues of precise eribulin... 
Halichondrin | Eribulin | Oxy-Micheal addition | Macrocycles | HALICHONDRIN-B | CYTOSKELETON | BUILDING-BLOCKS | CHEMISTRY, ORGANIC | STEREOSELECTIVE-SYNTHESIS | OXA-MICHAEL REACTION | TUBULIN | POLYHALOGENATED NUCLEOPHILES
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 11/2015, Volume 76, Issue 5, pp. 897 - 907
The California Cancer Consortium completed a phase I trial of E7389 (eribulin mesylate), an analog of the marine natural product halichondrin B. This trial was... 
Pharmacodynamics | Eribulin | Medicine & Public Health | Phase I trial | Oncology | Cancer Research | Halichondrin B analog | Pharmacology/Toxicology | Pharmacokinetics | VINCA DOMAIN | MESYLATE E7389 | PACLITAXEL RESISTANCE | HOMOHALICHONDRIN-B | SENSITIVITY | MARINE NATURAL-PRODUCTS | CELL LUNG-CANCER | BREAST-CANCER | ONCOLOGY | DRUGS | PHARMACOLOGY & PHARMACY | TUBULIN MUTATIONS | Melanoma - blood | Lung Neoplasms - drug therapy | Injections, Intravenous | Febrile Neutropenia - chemically induced | Tubulin Modulators - pharmacology | Furans - pharmacology | Humans | Middle Aged | Salvage Therapy | Male | Antineoplastic Agents - therapeutic use | Furans - adverse effects | Furans - therapeutic use | Dose-Response Relationship, Drug | Furans - pharmacokinetics | Urologic Neoplasms - drug therapy | Antineoplastic Agents - adverse effects | Ketones - blood | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Ketones - therapeutic use | Ovarian Neoplasms - drug therapy | Ketones - adverse effects | Tubulin Modulators - blood | Carcinoma - drug therapy | Ketones - pharmacology | Carcinoma - blood | Tubulin Modulators - adverse effects | Tubulin Modulators - pharmacokinetics | Ovarian Neoplasms - blood | Breast Neoplasms - drug therapy | Furans - blood | Tubulin Modulators - therapeutic use | Urologic Neoplasms - blood | Ketones - pharmacokinetics | Melanoma - drug therapy | Antineoplastic Agents - blood | Breast Neoplasms - blood | Aged | Lung Neoplasms - blood | Drug Monitoring | Lymphopenia - chemically induced | Index Medicus
Journal Article
BIOMOLECULES, ISSN 2218-273X, 11/2019, Volume 9, Issue 11, p. 679
Cancer is a heterogeneous disease and one of the major issues of health concern, especially for the public health system globally. Nature is a source of... 
HALICHONDRIN-B | ANTIPROLIFERATIVE ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-CYCLE ARREST | phytomedicine | CYTOTOXIC ACTIVITY | anticancer | COLON-CANCER | natural products | BREAST-CANCER CELLS | CHEMICAL-COMPOSITION | GROWTH IN-VITRO | NF-KAPPA-B | phytochemical | LEAF ESSENTIAL OIL
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2011, Volume 21, Issue 6, pp. 1639 - 1643
Journal Article
Journal Article
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9769, pp. 914 - 923
Journal Article
Journal Article
Natural Product Reports, ISSN 0265-0568, 12/2013, Volume 31, Issue 1, pp. 35 - 6
Journal Article
Natural product reports, ISSN 0265-0568, 01/2014, Volume 31, Issue 1, pp. 35 - 60
Covering: up to March 2013. In addition to their prominent role in basic biological and chemical research, natural products are a rich source of commercial... 
Biological Products - chemistry | Drug Industry | Humans | Drug Design | Biological Products - pharmacology | Molecular Structure | Drug Discovery
Journal Article