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index medicus (85) 85
sphingomonas-paucimobilis ut26 (68) 68
haloalkane dehalogenase (64) 64
enzymes (51) 51
haloalkane dehalogenase linb (44) 44
hydrolases - metabolism (38) 38
gamma-hexachlorocyclohexane (36) 36
biotechnology & applied microbiology (35) 35
analysis (33) 33
biochemistry & molecular biology (33) 33
degradation (33) 33
chlorofluorocarbons (32) 32
hydrolases - chemistry (30) 30
substrate specificity (26) 26
beta-hexachlorocyclohexane (25) 25
hydrolases - genetics (25) 25
microbiology (25) 25
crystal-structure (24) 24
kinetics (24) 24
catalysis (22) 22
biodegradation, environmental (20) 20
bioremediation (20) 20
lindane - metabolism (20) 20
biochemical research methods (18) 18
biodegradation (17) 17
hexachlorocyclohexane (17) 17
molecular sequence data (17) 17
alpha-hexachlorocyclohexane (16) 16
biocatalysis (16) 16
environmental sciences (16) 16
models, molecular (16) 16
proteins (16) 16
xanthobacter-autotrophicus gj10 (16) 16
amino acid sequence (14) 14
bacteria (14) 14
bacterial proteins - chemistry (14) 14
biotechnology (14) 14
bacterial proteins - metabolism (13) 13
purification (13) 13
cloning (12) 12
protein engineering (12) 12
pseudomonas-paucimobilis (12) 12
specificity (12) 12
bacteria - metabolism (11) 11
bacterial proteins - genetics (11) 11
biophysics (11) 11
chemistry (11) 11
delta-hexachlorocyclohexane (11) 11
enzyme (11) 11
pollutants (11) 11
catalytic mechanism (10) 10
life sciences (10) 10
mechanism (10) 10
protein conformation (10) 10
stereoisomerism (10) 10
structure (10) 10
1,2-dichloroethane (9) 9
animals (9) 9
biochemistry (9) 9
catalytic domain (9) 9
dehalogenase (9) 9
enzyme stability (9) 9
fluorescence (9) 9
lindane - chemistry (9) 9
mutagenesis, site-directed (9) 9
site-directed mutagenesis (9) 9
binding (8) 8
binding sites (8) 8
biotransformation (8) 8
enzyme kinetics (8) 8
gene expression (8) 8
genes (8) 8
halides (8) 8
haloalkane dehalogenases (8) 8
hexachlorocyclohexane-degrading bacterium (8) 8
hydrogen-ion concentration (8) 8
linb (8) 8
lindane (8) 8
lyases - metabolism (8) 8
molecular-dynamics (8) 8
recombinant proteins - genetics (8) 8
recombinant proteins - metabolism (8) 8
soil microbiology (8) 8
sphingomonadaceae - enzymology (8) 8
cloning, molecular (7) 7
crystallography, x-ray (7) 7
dechlorination (7) 7
degrading bacterium (7) 7
directed evolution (7) 7
enantioselectivity (7) 7
evolution (7) 7
halogenation (7) 7
hch (7) 7
hydrocarbons, brominated - metabolism (7) 7
hydrocarbons, halogenated - metabolism (7) 7
hydrolases (7) 7
insecticides - metabolism (7) 7
isomers (7) 7
molecular dynamics (7) 7
molecular dynamics simulation (7) 7
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Journal Article
Archives of Microbiology, ISSN 0302-8933, 10/2007, Volume 188, Issue 4, pp. 313 - 325
The technical formulation of hexachlorocyclohexane (HCH) mainly consists of the insecticidal γ-isomer and noninsecticidal α-, β-, and δ-isomers, among which... 
Life Sciences | Biochemistry, general | Biotechnology | Microbial Ecology | Hexachlorocyclohexane | Sphingomonads | Microbiology | Ecology | Haloalkane dehalogenase | Environmental pollutant | Cell Biology | DELTA-HEXACHLOROCYCLOHEXANE | hexachlorocyclohexane | SPHINGOMONAS-PAUCIMOBILIS UT26 | haloalkane dehalogenase | ESCHERICHIA-COLI | DEHYDROCHLORINASE LINA | ALPHA-HEXACHLOROCYCLOHEXANE | DEGRADING BACTERIUM | MICROBIOLOGY | SOIL BACTERIUM | PSEUDOMONAS-PAUCIMOBILIS | GENES | environmental pollutant | sphingomonads | CATALYTIC MECHANISM | Gene Duplication | Hydrolases - genetics | Sphingomonadaceae - isolation & purification | Molecular Sequence Data | Substrate Specificity | DNA, Bacterial - chemistry | Recombinant Proteins - isolation & purification | Cyclohexanols - metabolism | Sphingomonadaceae - metabolism | Base Sequence | Cloning, Molecular | Sphingomonadaceae - genetics | Lindane - metabolism | Biodegradation, Environmental | Hydrolases - metabolism | Recombinant Proteins - metabolism | Gene Expression | Mutagenesis, Site-Directed | Soil Microbiology | Japan | Models, Molecular | Recombinant Proteins - genetics | Binding Sites - genetics | Sequence Analysis, DNA | DNA Transposable Elements | Hydrolases - isolation & purification | Sequence Homology, Amino Acid | Soil Pollutants - metabolism | DNA, Bacterial - genetics | Plasmids | Sphingomonadaceae - classification | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2003, Volume 278, Issue 46, pp. 45094 - 45100
Haloalkane dehalogenases are bacterial enzymes capable of carbon-halogen bond cleavage in halogenated compounds. To obtain insights into the mechanism of the... 
SUBSTRATE CLASS | EVOLUTION | SPECIFICITY | HALIDE-BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | X-RAY-STRUCTURE | KINETIC-ANALYSIS | STEADY-STATE | MUTATIONS | SITE-DIRECTED MUTAGENESIS | HEXACHLOROCYCLOHEXANE-DEGRADING BACTERIUM | bromocyclohexane | LinB protein | haloalkane dehalogenase | 1-chlorohexane | chlorocyclohexane
Journal Article
Journal Article
高等学校化学研究:英文版, ISSN 1005-9040, 2009, Volume 25, Issue 4, pp. 556 - 559
The haloalkane dehalogenase LinB from Sphingomonas paucimobills UT26 was found to transform the 1,2,3-trichloropropane(TCP) into inorganic halide ions and... 
TCP | 相互作用 | 二氯丙醇 | 技术合作 | 催化活性 | 分子动力学模拟 | 脱卤酶 | 三氯丙烷 | Docking | 1,2,3-Trichloropropane | Haloalkane dehalogenase | Molecular dynamics simulation | SPHINGOMONAS-PAUCIMOBILIS UT26 | MECHANISM | SPECIFICITY | DYNAMICS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article