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Nature Neuroscience, ISSN 1097-6256, 09/2004, Volume 7, Issue 9, pp. 954 - 960
The E693Q mutation in the amyloid beta precursor protein (APP) leads to cerebral amyloid angiopathy (CAA), with recurrent cerebral hemorrhagic strokes and... 
DUTCH-TYPE | ALZHEIMERS-DISEASE | PRECURSOR-PROTEIN | SMOOTH-MUSCLE-CELLS | HCHWA-D | ANGIOPATHY | CEREBROSPINAL-FLUID | GAMMA-SECRETASE | NEUROSCIENCES | TRANSGENIC MICE | MUTANT PRESENILINS
Journal Article
Brain Research, ISSN 0006-8993, 2015, Volume 1622, pp. 149 - 162
Journal Article
JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, 05/2004, Volume 339, Issue 1, pp. 145 - 159
A new early-onset form of Alzheimer's disease (AD) was described recently where a point mutation was discovered in codon 693 of the beta-amyloid (Abeta)... 
FIBRIL FORMATION | arctic mutation | DUTCH-TYPE | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VITRO | amyloid | BETA-PROTEIN FIBRILLOGENESIS | A-BETA | protofibrils | CENTRAL-NERVOUS-SYSTEM | HCHWA-D | HEREDITARY CEREBRAL-HEMORRHAGE | PRECURSOR PROTEIN | kinetics | Alzheimer's disease
Journal Article
Journal of Genetic Counseling, ISSN 1059-7700, 10/2015, Volume 24, Issue 5, pp. 862 - 871
Journal Article
JNEN: Journal of Neuropathology & Experimental Neurology, ISSN 0022-3069, 01/2001, Volume 60, Issue 1, pp. 94 - 104
Immunohistochemical analysis of brains of patients with Alzheimer disease (AD) revealed that the cysteine proteinase inhibitor cystatin C colocalizes with... 
Cerebral amyloid angiopathy (CAA) | β amyloid precursor protein (βAPP) | Alzheimer disease (AD) | Amyloid β-protein (Aβ) | Hereditary cerebral hemorrhage with amyloidosis, Icelandic type (HCHWA-I) | Hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D) | ALLELE | amyloid beta-protein (A beta) | hereditary cerebral hemorrhage with amyloidosis, Icelandic type (HCHWA-I) | PATHOLOGY | NEUROSCIENCES | PEPTIDE | CLINICAL NEUROLOGY | hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D) | DUTCH TYPE | GAMMA-TRACE | MUTATION | cerebral amyloid angiopathy (CAA) | ANGIOPATHY | HEREDITARY CEREBRAL-HEMORRHAGE | PRECURSOR PROTEIN | INHIBITORS | beta amyloid precursor protein (beta APP) | APOLIPOPROTEIN-E EPSILON-2 | Immunohistochemistry | Pyramidal Cells - metabolism | Humans | Middle Aged | Cerebral Cortex - metabolism | Microscopy, Immunoelectron | Alzheimer Disease - pathology | Cerebral Cortex - ultrastructure | Brain - metabolism | Tissue Distribution | Amyloid - metabolism | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Cystatin C | Aged, 80 and over | Female | Peptide Fragments - metabolism | Mice, Transgenic - genetics | Cystatins - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Alzheimer Disease - metabolism | Aged | Mice | Amyloid beta-Peptides - chemistry | Index Medicus
Journal Article
JOURNAL OF NEUROSCIENCE RESEARCH, ISSN 0360-4012, 10/2007, Volume 85, Issue 13, pp. 2917 - 2923
Hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D), is an autosomal dominant disorder caused by the Dutch mutation (E693Q) in the P-amyloid... 
PROTEIN | Dutch type (HCHWA-D) | ALZHEIMERS-DISEASE | BETA-PEPTIDE | BRAIN MICROVESSELS | MUSCLE-CELLS | NEUROSCIENCES | amyloid beta(A beta) | hereditary cerebral hemorrhage with amyloidosis | A-BETA | cerebral amyloid angiopathy (CAA) | HCHWA-D | ANGIOPATHY | MUTATIONS | TRANSGENIC MICE
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 10/2007, Volume 85, Issue 13, pp. 2917 - 2923
Hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA‐D), is an autosomal dominant disorder caused by the Dutch mutation (E693Q) in the β‐amyloid... 
hereditary cerebral hemorrhage with amy‐loidosis, Dutch type (HCHWA‐D) | amyloid β(Aβ) | cerebral amyloid angio‐pathy (CAA) | Cerebral amyloid angiopathy (CAA) | Amyloid β(Aβ) | Hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D)
Journal Article