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PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 4, p. e94621
Journal Article
Cancer research (Chicago, Ill.), ISSN 1538-7445, 2010, Volume 70, Issue 4, pp. 1469 - 1478
Journal Article
The Journal of cell biology, ISSN 0021-9525, 11/2003, Volume 163, Issue 4, pp. 847 - 857
Transcriptional repression of E-cadherin, characteristic of epithelial to mesenchymal transition, is often found also during tumor cell invasion... 
Cell culture techniques | HCT116 cells | B lymphocytes | Epithelial cells | Cell adhesion | Colorectal cancer | Cadherins | Cultured cells | Slugs | Cells | β-catenin | Tumorigenesis | Slug | ERK | beta-catenin | TUMOR PROGRESSION | CYCLIN D1 | TRANSCRIPTION FACTOR SNAIL | REPRESSES E-CADHERIN | EPITHELIAL-MESENCHYMAL TRANSITIONS | COLON-CARCINOMA CELLS | CELL BIOLOGY | cell adhesion | COLORECTAL-CANCER | ADHESION SYSTEM | RECEPTOR ACTIVATION | tumorigenesis | UP-REGULATION | Cell Line | Epithelial Cells - metabolism | Cadherins - metabolism | beta Catenin | Humans | Cell Transformation, Neoplastic - metabolism | Adherens Junctions - metabolism | Down-Regulation - physiology | Neoplasm Invasiveness - physiopathology | Transcription Factors - metabolism | Animals | Cell Adhesion - physiology | Homeostasis - physiology | Cell Line, Tumor | Cytoskeletal Proteins - metabolism | Signal Transduction - physiology | Trans-Activators - metabolism | Cell Differentiation - physiology | Gene Expression Regulation, Neoplastic - physiology | Snail Family Transcription Factors | Repressor Proteins - metabolism | Mitogen-Activated Protein Kinases - metabolism | Human | Cytoskeletal Proteins | Down-Regulation | Biochemistry, Molecular Biology | Gene Expression Regulation, Neoplastic | Homeostasis | Epithelial Cells | Cellular Biology | Cell Adhesion | Life Sciences | Cell Transformation, Neoplastic | Adherens Junctions | Cell Differentiation | Cancer | cell adhesion; β-catenin; slug; ERK; tumorigenesis
Journal Article
Oncogene, ISSN 0950-9232, 10/2011, Volume 30, Issue 41, pp. 4261 - 4274
In the presence of sustained DNA damage occurring in S-phase or G2, normal cells arrest before mitosis and eventually become senescent... 
cyclin B1 | ATM | Chk2 | G2-M checkpoint | cell cycle | GENOTOXIC STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOTIC CATASTROPHE | TRANSCRIPTIONAL REPRESSION | G CHECKPOINT | CELL BIOLOGY | GENOMIC INSTABILITY | RETINOBLASTOMA PROTEIN | ONCOLOGY | GENETICS & HEREDITY | P53-DEFICIENT CELLS | CELL-CYCLE EXIT | IONIZING-RADIATION | ATAXIA-TELANGIECTASIA | Protein Kinases - metabolism | G2 Phase Cell Cycle Checkpoints - physiology | Phosphorylation | Protein Kinases - genetics | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Immunoblotting | Male | Cyclin B1 - metabolism | Pyrones - pharmacology | Tumor Suppressor Protein p53 - genetics | Cell Cycle Proteins - antagonists & inhibitors | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | G2 Phase Cell Cycle Checkpoints - drug effects | RNA Interference | Tumor Suppressor Proteins - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Antineoplastic Agents - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | HCT116 Cells | Cell Cycle Proteins - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Tumor Suppressor Protein p53 - metabolism | Cyclin B1 - genetics | Morpholines - pharmacology | Signal Transduction - genetics | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Piperazines - pharmacology | G2 Phase Cell Cycle Checkpoints - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Checkpoint Kinase 2 | Bleomycin - pharmacology | Checkpoint Kinase 1 | Signal Transduction - physiology | DNA Damage | HeLa Cells | Cell division | Oxidative stress | Signal transduction | DNA damage | Cyclin-dependent kinases | Cell cycle | CHK2 protein | Epithelial cells | Mitosis | CHK1 protein | G2 phase | Genotoxicity | Osteosarcoma cells | p53 protein | Cyclin-dependent kinase | Chemotherapy | Fibroblasts | Cancer | Life Sciences | Biochemistry, Molecular Biology
Journal Article
Cancer cell, ISSN 1535-6108, 2015, Volume 28, Issue 6, pp. 815 - 829
Hierarchical organization of tissues relies on stem cells, which either self-renew or produce committed progenitors predestined for lineage differentiation... 
β-catenin | cancer stem cells | MYC | retinoids | Retinoids | Cancer stem cells | INTESTINAL EPITHELIUM | HOMEOSTASIS | RETINOIC ACID | PROTEIN | ONCOLOGY | PATHWAY | GENE-EXPRESSION | RECEPTOR | PROLIFERATION | BETA-CATENIN | CELL BIOLOGY | Intestinal Mucosa - metabolism | Cell Proliferation | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Homeodomain Proteins - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Phosphoproteins - metabolism | Neoplasm Metastasis | Transfection | Neoplastic Stem Cells - metabolism | RNA Interference | Time Factors | Cell Transformation, Neoplastic - genetics | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Neoplastic Stem Cells - pathology | Female | Antineoplastic Agents - pharmacology | Cell Differentiation | Tumor Cells, Cultured | Colorectal Neoplasms - metabolism | Caco-2 Cells | Tissue Culture Techniques | HCT116 Cells | Mice, Inbred C57BL | Mice, Transgenic | Phosphoproteins - genetics | Cell Transformation, Neoplastic - metabolism | Homeodomain Proteins - genetics | HT29 Cells | Feedback, Physiological | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Aged | Cell Transformation, Neoplastic - pathology | Colorectal Neoplasms - pathology | Retinoids - pharmacology | Intestinal Mucosa - pathology | Development and progression | Developmental biology | Colorectal cancer | Stem cells | Prevention | Resveratrol | Transplantation | Metastasis | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0181183
.... Previous studies have shown that ursodeoxycholic acid (UDCA) suppresses the proliferation of colon cancer cells... 
DEOXYCHOLIC-ACID | APOPTOSIS | INFLAMMATORY-BOWEL-DISEASE | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | CHEMOPREVENTIVE AGENT | RISK | CYCLE PROGRESSION | NF-KAPPA-B | PRIMARY SCLEROSING CHOLANGITIS | SUSTAINED ERK PHOSPHORYLATION | Neoplastic Stem Cells - cytology | Cyclin-Dependent Kinases - metabolism | Reactive Oxygen Species - metabolism | Neoplastic Stem Cells - drug effects | HCT116 Cells | Humans | RNA, Messenger - metabolism | Colonic Neoplasms - metabolism | HT29 Cells | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Ursodeoxycholic Acid - pharmacology | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Mitogen-Activated Protein Kinase 3 - metabolism | Neoplastic Stem Cells - metabolism | Cell Cycle Checkpoints - drug effects | Colonic Neoplasms - pathology | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Cell Proliferation - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Oxidative Stress - drug effects | Cyclin-Dependent Kinases - genetics | Real-Time Polymerase Chain Reaction | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Mitogen-Activated Protein Kinase 1 - metabolism | Cell proliferation | Oxidative stress | Reactive oxygen species | Colon cancer | Growth | Analysis | Cancer cells | Ursodiol | Research | Fluorescein isothiocyanate | Cell culture | Flow cytometry | Regulations | Biotechnology | GTP-binding protein | Phosphorylation | Colorectal cancer | Fluorescence | Staining | Bromodeoxyuridine | mRNA | Cancer therapies | Phase transitions | Cyclin-dependent kinase 4 | Western blotting | Ursodeoxycholic acid | Cell growth | Rodents | Gastroenterology | Cell cycle | Colon | Inhibition | Immunoglobulins | Internal medicine | Extracellular signal-regulated kinase | Isothiocyanate | Tumor cell lines | Cell counters | Cyclin-dependent kinase 2 | Polymerase chain reaction | Medicine | Inhibitors | Microscopy | Fluorescein | Intracellular | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0174241
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 7/2011, Volume 68, Issue 1, pp. 227 - 238
Journal Article
Nature cell biology, ISSN 1476-4679, 2018, Volume 20, Issue 8, pp. 966 - 978
Metastatic seeding by disseminated cancer cells principally occurs in perivascular niches... 
NERVOUS-SYSTEM | LUNG | STEM-CELLS | BRAIN METASTASIS | TRANSLATIONAL PROFILING APPROACH | INTEGRIN | ENDOTHELIAL-CELLS | ADHESION MOLECULE L1 | TUMOR-GROWTH | CO-OPTION | CELL BIOLOGY | Cell Proliferation | Capillaries - pathology | Humans | Neural Cell Adhesion Molecule L1 - genetics | Tumor Microenvironment | Male | Phosphoproteins - metabolism | Brain Neoplasms - metabolism | Brain Neoplasms - secondary | Time Factors | Pericytes - pathology | Cell Shape | HEK293 Cells | Trans-Activators - genetics | Female | Neural Cell Adhesion Molecule L1 - metabolism | Capillaries - metabolism | Protein-Serine-Threonine Kinases - metabolism | Tissue Culture Techniques | HCT116 Cells | Mice, Inbred C57BL | Pericytes - metabolism | Protein-Serine-Threonine Kinases - genetics | Brain Neoplasms - genetics | Cell Communication | Phosphoproteins - genetics | Cell Adhesion | Integrin beta1 - metabolism | Mechanotransduction, Cellular | Animals | Adaptor Proteins, Signal Transducing - genetics | Mice, Inbred NOD | Trans-Activators - metabolism | Transcription Factors | Adaptor Proteins, Signal Transducing - metabolism | Integrin beta1 - genetics | Cell Movement | Metastasis | Kinases | Seeding | Metastases | Cell adhesion molecules | Cell adhesion & migration | Proteins | Cell adhesion | Capillaries | ILK protein | Neural cell adhesion molecule | Invasiveness | Organs | Molecular chains | Latency | Yes-associated protein | Signaling | Spreading | Pericytes | Infiltration | Mechanotransduction | Colonization | Cell migration | Niches | Cancer
Journal Article
Cancer cell, ISSN 1535-6108, 2011, Volume 19, Issue 3, pp. 387 - 400
Journal Article