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FEBS Letters, ISSN 0014-5793, 2009, Volume 583, Issue 12, pp. 1817 - 1824
The IQGAP family comprises three proteins in humans. The best characterized is IQGAP1, which participates in protein–protein interactions and integrates... 
Tumorigenesis | IQGAP1 | Metastasis | IQGAP2 | Neoplasia | IQGAP3 | Cancer | extracellular signal-regulated kinase | CK1 | mitogen-activated protein kinase | GSK-3β | casein kinase 1 | fibroblast growth factor | GTPase-activating protein | glycogen synthase kinase-3β | hepatocellular carcinoma | FGF | EGF | VEGF | HCC | MAPK | ECM | MMP | MEK | APC | adenomatous polyposis coli | GAP | MAPK kinase | matrix metalloproteinase | epidermal growth factor | vascular endothelial-derived growth factor | extracellular matrix | ERK | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION PROFILES | E-CADHERIN | BINDING PROTEIN | CELL BIOLOGY | RASGAP-RELATED PROTEIN | BIOPHYSICS | EPITHELIAL-CELLS | CYTOSKELETAL REORGANIZATION | GASTRIC-CANCER | PROSTATE-CANCER | PROTEOMIC ANALYSIS | CELL-CELL ADHESION | Neoplasms - metabolism | Cell Proliferation | Neoplasms - etiology | ras GTPase-Activating Proteins - chemistry | Humans | GTPase-Activating Proteins - metabolism | Exocytosis | Neoplasm Proteins - metabolism | MAP Kinase Signaling System | ras GTPase-Activating Proteins - genetics | Neoplasms - genetics | Transcription, Genetic | Molecular Structure | Neoplasm Proteins - genetics | Genes, Tumor Suppressor | Oncogenes | Protein Structure, Tertiary | ras GTPase-Activating Proteins - metabolism | Neoplasm Proteins - chemistry | GTPase-Activating Proteins - chemistry | Cell Adhesion | beta Catenin - metabolism | Neoplasm Metastasis - genetics | Neoplasm Metastasis - physiopathology | Protein Binding | GTPase-Activating Proteins - genetics | Cell Movement | Liver cancer | Chromatin | Synthesis | Casein | Glycogen | Calcium-binding proteins | Protein kinases | Vascular endothelial growth factor | Growth factors | Protein binding
Journal Article
Human Vaccines & Immunotherapeutics, ISSN 2164-5515, 11/2014, Volume 10, Issue 11, pp. 3270 - 3285
Research on innate immune signaling and regulation has recently focused on pathogen recognition receptors (PRRs) and their signaling pathways. Members of PRRs... 
IFI16, interferon, gamma-inducible protein 16 | IRF, interferon regulatory factor | CDNs, cyclic dinucleotides | AIM2, absent in melanoma 2 | LT, lethal toxin | MIB, mind bomb | ALRs, AIM2-like receptors | MDP, muramyl dipeptide | LUBAC, linear ubiquitin assembly complex | innate immunity | TRIF, TIR domain-containing adaptor inducing IFN-b | DDX41, DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | IKK, IkB kinase | MyD88, myeloid differentiation factor 88 | TRAILR, tumor-necrosis factor-related apoptosis-inducing ligand receptor | AMPK, AMP activated protein kinase | LBP, LPS-binding protein | NEMO, NF-kB essential modulator | TRIMs, tripartite motif containing proteins | IKKi, inducible IkB kinase | PKC-d, protein kinase C delta | LRR, leucine-rich repeat | TAK1, TGF-b-activating kinase 1 | RIP, receptor-interacting protein | TBK1, TANK binding kinase 1 | TRIP, TRAF-interacting protein | TLRs, Toll-like receptors | LGP 2, laboratory of genetics and physiology 2 | PKR, dsRNA-dependent protein kinase | PRRs, pathogen recognition receptors | STING, stimulator of interferon gene | GBP5, guanylate-binding protein 5 | RLRs, RIG-I-like receptors | ULK1, autophagy related serine threonine UNC-51- like kinase | TIR, Toll IL-1 receptor | LPS, lipopolysaccharide | TRAF, TNFR-associated factor | Atg16L, autophagy related 16-like | cDC, conventional dendritic cell | MDA5, melanoma differentiation-associated protein 5 | DCs, dendritic cells | CARD, caspase recruitment domain | PRRs | KSHV, Kaposi's sarcoma-associated herpesvirus | RAUL, RTA-associated E3 ligase | CLRs, C-type lectin receptors | pDC, plasmacytoid dendritic cell | MAVS, mitochondrial antiviral signaling protein | inflammation | NAIPs, neuronal apoptosis inhibitory proteins | CYLD, the familial cylindromatosis tumor suppressor gene | SIGIRR, single Ig IL-1-related receptor | ROS, reactive oxygen species | RIG-I, retinoic acid-inducible gene 1 | TANK, TRAF family-member-associated NF-kB activator | ASC, apoptosis-associated speck-like protein containing a CARD | DAMPs, danger-associated molecular patterns | IFN, interferon | TRAM, TRIF-related adaptor molecule | TIRAP, TIR domain-containing adapter protein | iE-DAP, g-D-glutamyl-meso-diaminopimelic acid | PAMPs, pathogen-associated molecular patterns | cGAS, cyclic GMP-AMP synthase | cIAP, cellular inhibitor of apoptosis protein | GSK3β, Glycogen synthase kinase 3β | NOD, nucleotide-binding oligomerization domain | IRAK, interleukin-1 receptor-associated kinase | BMM, bone marrow-derived macrophage | type I interferon | RACK1, receptor for activated C kinase 1 | SARM, sterile a- and armadillo motif-containing protein | SOCS, suppressor of cytokine signaling | CMV, cytomegalovirus | cancer | NLRs, Nod- like receptors | Nrdp1, neuregulin receptor degradation protein 1 | HCC, hepatocellular carcinoma | ER, endoplasmic reticulum | Innate immunity | Inflammation | Type I interferon | Cancer | linear ubiquitin assembly complex | C-type lectin receptors | IKKi | TRIP | TRAF | apoptosis-associated speck-like protein containing a CARD | I INTERFERON INDUCTION | neuregulin receptor degradation protein 1 | RIG-I | TRAM | CARD | TRIF-related adaptor molecule | dendritic cells | TBK1 | cytomegalovirus | cyclic dinucleotides | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | cellular inhibitor of apoptosis protein | GSK3 | PAMPs | retinoic acid-inducible gene 1 | CDNs | hepatocellular carcinoma | TANK binding kinase 1 | RAUL | GBP5 | Toll IL-1 receptor | cDC | MIB | protein kinase C delta | iE-DAP | CMV | SARM | SIGIRR | IRAK | sterile a- and armadillo motif-containing protein | cyclic GMP-AMP synthase | TNFR-associated factor | autophagy related serine threonine UNC-51-like kinase | AMPK | ULK1 | lipopolysaccharide | TRIF | IRF | RLRs | Nrdp1 | receptor-interacting protein | LPS-binding protein | plasmacytoid dendritic cell | tripartite motif containing proteins | LPS | ANTIVIRAL SIGNAL-TRANSDUCTION | DAMPs | melanoma differentiation-associated protein 5 | ASC | TAK1 | KSHV | LGP 2 | neuronal apoptosis inhibitory proteins | TRIMs | danger-associated molecular patterns | cGAS | RIG-I-like receptors | lethal toxin | OXYGEN SPECIES PRODUCTION | BMM | muramyl dipeptide | interleukin-1 receptor-associated kinase | IKK | AMP activated protein kinase | absent in melanoma 2 | IkB kinase | CYLD | dsRNA-dependent protein kinase | MAVS | Kaposi's sarcoma-associated herpesvirus | TIR domain-containing adaptor inducing IFN-b | STING | TIR | TOLL-LIKE-RECEPTORS | AIM2-like receptors | laboratory of genetics and physiology 2 | DDX41 | IMMUNOLOGY | LRR | MyD88 | nucleotide-binding oligomerization domain | CLRs | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | myeloid differentiation factor 88 | MDP | RACK1 | LBP | TRAF-interacting protein | bone marrow-derived macrophage | NF-KAPPA-B | NOD-LIKE RECEPTOR | NOD | conventional dendritic cell | NLRP3 INFLAMMASOME ACTIVATION | HCC | TGF-b-activating kinase 1 | inducible IkB kinase | TIRAP | Atg16L | mind bomb | pathogen-associated molecular patterns | AIM2 | PKR | TRAF family-member-associated NF-kB activator | ROS | interferon regulatory factor | g-D-glutamyl-meso-diaminopimelic acid | pathogen recognition receptors | NLRs | UBIQUITIN-DEPENDENT KINASE | DEUBIQUITINATING ENZYME CYLD | NEMO | stimulator of interferon gene | RTA-associated E3 ligase | Nod- like receptors | the familial cylindromatosis tumor suppressor gene | tumor-necrosis factor-related apoptosis-inducing ligand receptor | TANK | MDA5 | IFN | mitochondrial antiviral signaling protein | ALRs | IFI16 | DCs | TRAILR | reactive oxygen species | Toll-like receptors | cIAP | TIR domain-containing adapter protein | PATTERN-RECOGNITION RECEPTORS | single Ig IL-1-related receptor | guanylate-binding protein 5 | suppressor of cytokine signaling | autophagy related 16-like | leucine-rich repeat | NF-kB essential modulator | Glycogen synthase kinase 3 | SOCS | interferon | LUBAC | caspase recruitment domain | pDC | NAIPs | receptor for activated C kinase 1 | PKC-d | RIP | gamma-inducible protein 16 | TLRs | endoplasmic reticulum | Immunity, Innate - immunology | Signal Transduction - immunology | Neoplasms - immunology | Humans | Inflammasomes - immunology | RNA Viruses - immunology | Toll-Like Receptors - immunology | Interferon Type I - immunology | DNA Viruses - immunology
Journal Article
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 08/2017, Volume 138, pp. 49 - 60
The serine-threonine protein phosphatase family members are known as critical regulators of various cellular functions, such as survival and transformation.... 
AMPK | HCC | Phosphatase inhibitor | PP5 | Carcinogenesis | CANCER-CELLS | TPR DOMAIN | REGULATOR | SERINE/THREONINE PHOSPHATASES | HEPATOCELLULAR-CARCINOMA | IN-VITRO | GROWTH ARREST | PHARMACOLOGY & PHARMACY | INHIBITORS | PROTEIN-PHOSPHATASE-5 | Apoptosis - drug effects | Humans | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Carcinogenesis - metabolism | Carcinoma, Hepatocellular - drug therapy | RNA Interference | Gene Deletion | Protein Tyrosine Phosphatases, Non-Receptor - genetics | Liver Neoplasms - pathology | Neoplasm Proteins - genetics | Enzyme Inhibitors - pharmacology | Enzyme Induction | Random Allocation | Recombinant Fusion Proteins - chemistry | Enzyme Inhibitors - therapeutic use | AMP-Activated Protein Kinases - chemistry | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Phosphoprotein Phosphatases - genetics | Mice, Nude | Liver Neoplasms - metabolism | Survival Analysis | Cell Line, Tumor | AMP-Activated Protein Kinases - genetics | Carcinoma, Hepatocellular - metabolism | Protein Tyrosine Phosphatases, Non-Receptor - antagonists & inhibitors | AMP-Activated Protein Kinases - metabolism | Phosphoprotein Phosphatases - metabolism | Neoplasm Proteins - metabolism | Recombinant Fusion Proteins - metabolism | Liver Neoplasms, Experimental - metabolism | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | HEK293 Cells | Antineoplastic Agents - pharmacology | Liver Neoplasms, Experimental - pathology | Nuclear Proteins - genetics | Liver Neoplasms - drug therapy | Nuclear Proteins - metabolism | Phosphoprotein Phosphatases - antagonists & inhibitors | Enzyme Activation - drug effects | Carcinogenesis - drug effects | Animals | Liver Neoplasms, Experimental - drug therapy | Neoplasm Proteins - agonists | Tumor Burden - drug effects | Nuclear Proteins - antagonists & inhibitors | Protein Tyrosine Phosphatases, Non-Receptor - metabolism | Carcinoma, Hepatocellular - pathology | Neoplasm Staging | Protein kinases | Phosphatases | Immunohistochemistry | Medical colleges | Corticosteroids | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0153882
Epidemiological studies have validated the association between hepatitis C virus (HCV) infection and hepatocellular carcinoma (HCC). An increasing number of... 
PATHWAYS | APOPTOSIS | COMPLEX | REPLICATION | NS5A | LANDSCAPE | MULTIDISCIPLINARY SCIENCES | EXPRESSION | P53 | NS3 | Hepatitis C, Chronic - metabolism | Cell Proliferation | Signal Transduction | Humans | Hepacivirus - pathogenicity | Hepatitis C, Chronic - complications | Neoplasm Proteins - metabolism | Glycogen Synthase Kinase 3 beta - metabolism | Viral Proteins - metabolism | beta Catenin - metabolism | Hepacivirus - metabolism | Protein Interaction Maps | Liver Neoplasms - etiology | Algorithms | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Liver Neoplasms - pathology | Viral Nonstructural Proteins - metabolism | Carcinoma, Hepatocellular - etiology | Proto-Oncogene Proteins c-akt - metabolism | Carcinoma, Hepatocellular - metabolism | Cell Movement | Viral proteins | Physiological aspects | Development and progression | Genetic aspects | Research | Hepatoma | Hepatitis C virus | Protein-protein interactions | Cell proliferation | Wnt protein | Aviation | Pathogenesis | p53 Protein | Viruses | Hepatocellular carcinoma | AKT protein | Infections | Kinases | Epidemiology | Metastases | Proteins | Hepatitis | Liver cancer | β-catenin | Network analysis | HCc protein | Cell cycle | AKT1 protein | Liver diseases | Aerospace medicine | Random walk | MAP kinase | Gene expression | Disease control | Virology | Tumor necrosis factor | Plasmids | Hepatitis C | Protein interaction | Apoptosis
Journal Article
FEBS Letters, ISSN 0014-5793, 2004, Volume 557, Issue 1, pp. 73 - 80
Ligand activation of peroxisome proliferator‐activated receptor γ (PPARγ) has been reported to induce growth inhibition and apoptosis in various cancers... 
Peroxisome proliferator-activated receptor γ | Transactivation | Protein–protein interaction | Hepatitis B virus X protein | IFA, immunofluorescence assay | HBV, hepatitis B virus | HBx-TG, hepatitis B virus X protein transgenic | HBx, hepatitis B virus X protein | RXR, retinoid X receptor | DBD, DNA binding domain | NLS, nuclear localization signal | rHBx, recombinant hepatitis B virus X protein | PPARγ, peroxisome proliferator-activated receptor γ | PPRE, peroxisome proliferator response element | HA, hemagglutinin | NE, nuclear extract | HCC, hepatocellular carcinoma | EMSA, electrophoretic mobility shift assay | LBD, ligand binding domain | Protein-protein interaction | DNA-BINDING | TRANSCRIPTIONAL ACTIVITY | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | transactivation | CELL BIOLOGY | LIVER-CANCER | hepatitis B virus X protein | HUMAN PROSTATE-CANCER | HEPATOCELLULAR-CARCINOMA | BIOPHYSICS | RESPONSE ELEMENTS | protein-protein interaction | HEPATOMA-CELL LINES | peroxisome proliferator-activated receptor gamma | MOLECULAR-BASIS | TRANSGENIC MICE | Green Fluorescent Proteins | Adenoviridae | Transcription Factors - chemistry | Apoptosis - drug effects | Humans | Hepatitis B Antigens - chemistry | Protein Transport - drug effects | Trans-Activators - chemistry | Recombinant Fusion Proteins - metabolism | Recombinant Fusion Proteins - drug effects | Transcription Factors - drug effects | Transfection | Base Sequence | Receptors, Cytoplasmic and Nuclear - chemistry | Liver Neoplasms - pathology | Trans-Activators - pharmacology | Hepatitis B Antigens - pharmacology | Tumor Cells, Cultured | Genes, Reporter | Liver Neoplasms - virology | Cell Line | Receptors, Cytoplasmic and Nuclear - drug effects | Carcinoma, Hepatocellular - virology | Receptors, Cytoplasmic and Nuclear - genetics | Recombinant Fusion Proteins - chemistry | Transcription Factors - genetics | DNA Primers | Reverse Transcriptase Polymerase Chain Reaction | Cell Division - drug effects | Transcription Factors - metabolism | Carcinoma, Hepatocellular - pathology | Ligands | Luminescent Proteins - genetics | Trans-Activators - metabolism | Genetic Vectors | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article
Seminars in Cancer Biology, ISSN 1044-579X, 06/2018, Volume 50, pp. 77 - 89
The FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are... 
TO-MESENCHYMAL TRANSITION | IN-VITRO | ACTIVATED PROTEIN-KINASE | STEM-LIKE CELLS | ONCOLOGY | DNA-DAMAGE RESPONSE | ESTROGEN-RECEPTOR-ALPHA | JUN NH2-TERMINAL KINASE | FOXO TRANSCRIPTION FACTORS | FORKHEAD BOX M1 | NEGATIVE BREAST-CANCER | DNA Repair - drug effects | Humans | Gene Expression Regulation, Neoplastic | Antineoplastic Agents - therapeutic use | Neoplasms - drug therapy | Cell Self Renewal - genetics | Forkhead Box Protein O3 - genetics | Drug Resistance, Neoplasm - genetics | Neoplasms - genetics | Forkhead Box Protein M1 - genetics | Cell Proliferation - drug effects | Neoplasms - pathology | Drug Resistance, Neoplasm - drug effects | AURKA, aurora kinase A | Fox, forkhead box | Bim, B-cell lymphoma 2 interacting mediator | EGF, epidermal growth factor | JNK | BRIP1, BRCA1-interacting protein-terminal helicase 1 | GICs, glioma-initiating cells | MCL, mantle cell lymphoma | PKB, protein kinase B | SCs, stem cells | LEF, T-cell factor | Skp2, S-phase kinase-associated protein 2 | SSBs, single-strand breaks | mTOR, mammalian target of rapamycin | NBS1, Nijmegen breakage syndrome 1 | stress activated protein kinase | MEK, mitogen-activated protein kinase kinase | PIP3, phosphatidylinositol- 3,4,5-trisphosphate | BER, base excision repair | lymphoid enhancer factor | VEGF, vascular endothelial growth factor | AML, acute myeloid leukaemia | ER+ve, estreogen receptor positive | EXO1, exonuclease 1 | EGFR, epidermal growth factor receptor | MDR1, multidrug resistance protein 1 | ChIP-seq, chromatin immunoprecipitation with massively parallel DNA sequencing | ABCB1, ATP-binding cassette sub-family B member 1 | TCF | SOD-2, superoxide dismutase | TKIs, tyrosine kinase inhibitors | PDK, phosphoinositide-dependent kinase | IFNɣ, interferon-ɣ | BRCA2, breast cancer-associated gene 2 | DDR, DNA damage response | Cks1, cyclin-dependent kinases regulatory subunit 1 | ESR1, estrogen receptor alpha gene | NHEJ, non-homologous end joining | XRCC1, X-ray cross-complementing group 1 | OTUB1, OUT domain-containing ubiquitin aldehyde-binding protein 1 | IGF, insulin growth factor | TRAIL, tumour necrosis factor-related apoptosis inducing ligand | ER, estrogen receptor | MRN, MER11-RAD50-NBS1 | BRCA1, breast cancer susceptibility gene product 1 | FasL, fas ligand | RTKs, receptor tyrosine kinases | Sox1, sex determining region Y box 2 | GADD45, DNA damage-inducible protein 45 | MMR, mismatch repair | PI3K, phosphatidylinositol 3-kinase | ROS, reactive oxygen species | NAMPT, nicotinamide-phosphribosyltransferase | miRs, Micro-RNAs | FHRE, forkhead response element | ATM, Ataxia-telangiectasia mutated | NER, nucleotide excision repair | ERK, extracellular signal-regulated kinase | HR, homologous recombination | AMPK, adenosine monophosphate-activated protein kinase | DSBs, double strands breaks | PA, Psammaplysene A | CML, chronic myeloid leukaemia | HCC, hepatocellular carcinoma | Mst1, macrophage stimulating 1 | Rb2, retinoblastoma-related p130 | SAPK, c-Jun N-terminal kinase | CSCs, cancer stem cells
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Summary Bile acid (BA) transporters are critical for maintenance of the enterohepatic BA circulation where BAs exert their multiple physiological functions... 
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | RAT-LIVER | SALT EXPORT PUMP | GROWTH-FACTOR 19 | ORGANIC ANION TRANSPORTERS | 90-PERCENT PARTIAL-HEPATECTOMY | URSODEOXYCHOLIC ACID | PRIMARY BILIARY-CIRRHOSIS | FARNESOID-X-RECEPTOR | GASTROENTEROLOGY & HEPATOLOGY | PHOSPHOLIPID-ASSOCIATED CHOLELITHIASIS | FAMILIAL INTRAHEPATIC CHOLESTASIS | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
Journal Article