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Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2018, Volume 61, Issue 22, pp. 9976 - 9999
Due to the emergence of highly pathogenic and oseltamivir-resistant influenza viruses, there is an urgent need to develop new anti-influenza agents. Herein,... 
H5N1 | DESIGN | CHEMISTRY, MEDICINAL | REVERSE-TRANSCRIPTASE INHIBITORS | SMALL-MOLECULE INHIBITORS | POLYMERASE | DYNAMICS | NEURAMINIDASE-INHIBITOR | INFLUENZA-VIRUS | IDENTIFICATION | H1N1 | 4 acetamido 5 [(4 isopropylbenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | Medical and Health Sciences | pharmacokinetic parameters | drug potency | drug structure | ethyl 4 acetamido 5 [[4 (benzo[b]thiophen 5 yl)benzyl]amino] 3 (pentan 3 yloxy) cyclohex 1 ene 1 carboxylate | oseltamivir derivative | MDCK cell line | virus sialidase | ethyl 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (phenylthio)benzyl]amino]cyclohex 1 ene 1 carboxylate | 4 acetamido 5 [[4 (isobutylthio)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | 4 acetamido 3 (pentan 3 yloxy) 5 [(4 phenoxybenzyl)amino]cyclohex 1 ene 1 carboxylic acid | animal model | 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (thiophen 2 yl thio)benzyl]amino]cyclohex 1 ene 1 carboxylic acid | Basic Medicine | ribavirin | rat | Influenza A virus (H5N6) | antivirus agent | 4 acetamido 5 [[4 (cyclopentyl)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | human cell | Influenza A virus (H5N2) | antiviral activity | animal experiment | 4 acetamido 5 [[4 (benzo[b]thiophen 2 yl)benzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | 4 acetamido 5 [[4 (cyclohexylthio)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | 4 acetamido 5 [[4 (sec butylthio)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | zanamivir | nonhuman | 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (pentan 3 yloxy)benzyl]amino]cyclohex 1 ene 1 carboxylic acid | maximum concentration | diclofenac | 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (phenylsulfonyl)benzyl]amino]cyclohex 1 ene 1 carboxylic acid | drug clearance | drug stability | 4 acetamido 5 [[3 (cyclopentyl)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | unclassified drug | molecular model | plasma concentration-time curve | Medicin och hälsovetenskap | metabolic stability | 4 acetamido 5 [[3 (sec butylthio)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | Article | drug synthesis | Influenza A virus (H5N1) | 4 acetamido 5 amino 3 (1 ethylpropoxy) 1 cyclohexene 1 carboxylic acid | 4 acetamido 5 [(4 benzylbenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | propafenone | time to maximum plasma concentration | human | Influenza A virus (H5N8) | 4 acetamido 5 [(4 ethylbenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | testosterone | 4 acetamido 5 [(4 methoxybenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | bioassay | area under the curve | drug half life | Influenza A virus (H3N2) | 4 acetamido 5 [(4 benzoylbenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | controlled study | Influenza A virus | Medicinska och farmaceutiska grundvetenskaper | oseltamivir | unindexed drug | 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (phenylthio)benzyl]amino]cyclohex 1 ene 1 carboxylic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0167294
Mallotus philippensis L.(MP) commonly known as Kamala tree in Hindi, is a small to medium-sized monoecious tree. The objective of the study was to evaluate the... 
INDUCED PAW EDEMA | CARRAGEENAN | JAPONICUS | ASSAY | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | BIOLOGY | DISEASE | LIPID PEROXIDES | RATS | LEUKOTRIENES | Free Radical Scavengers - pharmacology | Inflammation - pathology | Plant Extracts - chemistry | Free Radical Scavengers - chemistry | Plant Extracts - pharmacology | Catalase - antagonists & inhibitors | Glutathione Peroxidase - antagonists & inhibitors | Flavanones - chemistry | Inflammation - drug therapy | Lipid Peroxidation - drug effects | Carrageenan - adverse effects | Granuloma - etiology | Cytokines - blood | Glutathione Peroxidase - metabolism | Mallotus Plant - chemistry | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Flavanones - pharmacology | Rats | Edema - drug therapy | Inflammation - etiology | Catalase - metabolism | Edema - etiology | Granuloma - pathology | Animals | Anti-Inflammatory Agents - chemistry | Granuloma - drug therapy | Edema - pathology | Physiological aspects | Granuloma | Carrageenin | Research | Cytokines | Methods | Dimethyl | Hydrocarbons | Lipids | Acetylsalicylic acid | Cotton | Interleukin 6 | Antioxidants | Catalase | Rodents | Interleukin 1 | Tumor necrosis factor-TNF | Peroxidase | Drug dosages | Methanol | Glutathione | Trees | Glutathione peroxidase | Edema | Albinism | Scavenging | Pharmacology | Inflammation | Tumor necrosis factor-α | Anti-inflammatory agents | Malondialdehyde | Chromatography | Chemistry | Carrageenan
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2016, Volume 108, pp. 301 - 308
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 386, Issue 10003, pp. 1537 - 1545
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7607, pp. 402 - 406
Journal Article
The Lancet Oncology, ISSN 1470-2045, 04/2018, Volume 19, Issue 4, pp. 562 - 578
Journal Article
11.