X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (19174) 19174
Publication (4180) 4180
Book Review (72) 72
Book Chapter (53) 53
Conference Proceeding (28) 28
Dissertation (7) 7
Data Set (6) 6
Magazine Article (4) 4
Reference (4) 4
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (18946) 18946
hek293 cells (18821) 18821
index medicus (18371) 18371
animals (10581) 10581
mice (6243) 6243
biochemistry & molecular biology (4203) 4203
cell biology (3742) 3742
proteins (3640) 3640
cell line, tumor (3380) 3380
male (3316) 3316
article (2973) 2973
multidisciplinary sciences (2765) 2765
expression (2701) 2701
female (2653) 2653
signal transduction (2383) 2383
cell line (2371) 2371
rats (2365) 2365
cancer (2364) 2364
activation (2346) 2346
pharmacology & pharmacy (2261) 2261
cells (2260) 2260
phosphorylation (2219) 2219
gene expression (2205) 2205
transfection (2156) 2156
analysis (2040) 2040
research (2009) 2009
research article (1990) 1990
protein binding (1975) 1975
mutation (1965) 1965
apoptosis (1922) 1922
cells, cultured (1833) 1833
mice, inbred c57bl (1721) 1721
medicine (1684) 1684
hela cells (1602) 1602
dose-response relationship, drug (1572) 1572
science (1551) 1551
biology (1487) 1487
physiological aspects (1446) 1446
signal transduction - drug effects (1417) 1417
amino acid sequence (1355) 1355
neurosciences (1334) 1334
cell survival - drug effects (1317) 1317
kinases (1317) 1317
oncology (1310) 1310
rna interference (1283) 1283
genetic aspects (1266) 1266
health aspects (1258) 1258
biochemistry (1243) 1243
protein (1241) 1241
molecular sequence data (1191) 1191
structure-activity relationship (1178) 1178
inhibition (1154) 1154
ligands (1132) 1132
rodents (1130) 1130
chemistry, medicinal (1122) 1122
in-vitro (1079) 1079
binding sites (1074) 1074
genes (1049) 1049
identification (1044) 1044
binding (1042) 1042
in-vivo (1017) 1017
cell proliferation - drug effects (1015) 1015
mice, knockout (1012) 1012
apoptosis - drug effects (947) 947
models, molecular (942) 942
physiology (924) 924
molecular biology (923) 923
blotting, western (917) 917
biophysics (906) 906
immunology (887) 887
rats, sprague-dawley (884) 884
pharmacology (882) 882
cell proliferation (848) 848
gene-expression (833) 833
gene (832) 832
antineoplastic agents - pharmacology (831) 831
calcium - metabolism (823) 823
receptors (801) 801
dna (796) 796
neurons (789) 789
medicine, research & experimental (779) 779
viruses (770) 770
enzymes (763) 763
gene expression regulation (752) 752
patch-clamp techniques (742) 742
protein structure, tertiary (738) 738
inflammation (737) 737
genetics & heredity (733) 733
tumors (730) 730
transcription (728) 728
molecular structure (725) 725
phosphorylation - drug effects (719) 719
oxidative stress (718) 718
rna (711) 711
receptor (708) 708
mice, inbred balb c (700) 700
cell membrane - metabolism (695) 695
life sciences (687) 687
mice, nude (680) 680
kinetics (668) 668
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (19115) 19115
Chinese (46) 46
Russian (10) 10
German (4) 4
Persian (2) 2
Japanese (1) 1
Korean (1) 1
Spanish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature, ISSN 0028-0836, 03/2015, Volume 519, Issue 7542, pp. 237 - 241
Journal Article
Circulation, ISSN 0009-7322, 04/2013, Volume 127, Issue 16, pp. 1677 - 1691
Background-Cardiotoxicity is a leading cause for drug attrition during pharmaceutical development and has resulted in numerous preventable patient deaths.... 
arrhythmias, cardiac | stem cells | induced pluripotent stem cells | LONG-QT | INDUCED ARRHYTHMIAS | POLYMORPHIC VENTRICULAR-TACHYCARDIA | CARDIAC & CARDIOVASCULAR SYSTEMS | SUDDEN-DEATH | QT INTERVAL PROLONGATION | DISCOVERY | CHANNEL | MODELS | TORSADE-DE-POINTES | PERIPHERAL VASCULAR DISEASE | MOLECULAR-BASIS | Cardiomyopathy, Dilated - pathology | Embryonic Stem Cells - cytology | Kidney - embryology | Cardiomyopathy, Hypertrophic, Familial - genetics | Humans | Ion Channels - genetics | Verapamil - toxicity | Gene Expression Profiling | HEK293 Cells - drug effects | Cell Line - drug effects | Nicorandil - toxicity | Cell Line - physiology | Myofibrils - ultrastructure | Drug-Related Side Effects and Adverse Reactions - genetics | Cell Differentiation | Induced Pluripotent Stem Cells - cytology | Action Potentials - drug effects | Cardiomyopathy, Dilated - genetics | Drug Evaluation, Preclinical - methods | Genetic Predisposition to Disease | Ion Channels - biosynthesis | Cardiomyopathy, Hypertrophic, Familial - pathology | Cell Size | Kidney - cytology | Long QT Syndrome - pathology | Embryonic Stem Cells - physiology | Embryoid Bodies - drug effects | Patch-Clamp Techniques | Myocytes, Cardiac - drug effects | Quinazolines - toxicity | HEK293 Cells - physiology | Myocytes, Cardiac - physiology | Long QT Syndrome - genetics | Cisapride - toxicity | In Vitro Techniques | Drugs | Usage | Analysis | Heart cells | Stem cells | Product/Service Evaluations | Research | Health aspects | Methods | Index Medicus | Abridged Index Medicus | cardiotoxicity | Induced pluripotent stem cells | arrhythmia
Journal Article
STEM CELLS, ISSN 1066-5099, 06/2013, Volume 31, Issue 6, pp. 1051 - 1063
Glioblastoma multiforme (GBM) is a life‐threatening brain tumor. Accumulating evidence suggests that eradication of glioma stem‐like cells (GSCs) in GBM is... 
Cancer stem cell | Glioblastoma stem cell | Neural stem cell | Glioblastoma | PLK1 | TARGET | SPECIFICITY | IDENTIFICATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | INHIBITION | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | HEMATOLOGY | TRANSCRIPTION FACTOR | PROMOTES | EXPRESSION | PROGRESSION | LEUCINE-ZIPPER KINASE | Phosphorylation | Neoplastic Stem Cells - drug effects | Humans | Brain Neoplasms - pathology | Mitosis - genetics | Brain Neoplasms - metabolism | Glioblastoma - genetics | Neoplastic Stem Cells - metabolism | Dacarbazine - pharmacology | Forkhead Transcription Factors - metabolism | Dacarbazine - analogs & derivatives | HEK293 Cells | Cell Cycle Proteins - genetics | Neoplastic Stem Cells - pathology | Glioblastoma - metabolism | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Cell Cycle Proteins - metabolism | Cells, Cultured | Neural Stem Cells - drug effects | Protein-Serine-Threonine Kinases - genetics | Brain Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Brain Neoplasms - drug therapy | Forkhead Transcription Factors - genetics | Neural Stem Cells - pathology | Peptides - pharmacology | Up-Regulation - drug effects | Animals | Mitosis - drug effects | Mitosis - physiology | Glioblastoma - pathology | Cell Proliferation - drug effects | Mice | Glioblastoma - drug therapy | Neural Stem Cells - metabolism | Chemotherapy | Gliomas | Analysis | Stem cells | Development and progression | Genetic engineering | Health aspects | Cancer | Kinases | Index Medicus | Cancer Stem Cells
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 8, pp. 2784 - 2789
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, pp. e23899 - e23899
The Wnt/beta-catenin signalling pathway shares a key component, beta-catenin, with the cadherin-based adhesion system. The signalling function of beta-catenin... 
TYROSINE PHOSPHORYLATION | WNT PATHWAY | DEPENDENT TRANSCRIPTION | FACTOR SCATTER FACTOR | BIOLOGY | TUMOR-SUPPRESSOR PROTEIN | ADHERENS JUNCTIONS | BETA-CATENIN | CELL-CELL ADHESION | NUCLEAR TRANSLOCATION | N-CADHERIN | Embryo, Mammalian - drug effects | Transcription, Genetic - drug effects | Epithelial Cells - metabolism | Cadherins - metabolism | Epithelial Cells - drug effects | Humans | Transcriptional Activation - drug effects | Mesoderm - drug effects | Cytoplasm - metabolism | Epithelial-Mesenchymal Transition - drug effects | Protein Transport - drug effects | Mesoderm - cytology | Epithelial-Mesenchymal Transition - genetics | Hepatocyte Growth Factor - pharmacology | Embryo, Mammalian - metabolism | Protein Binding - drug effects | HEK293 Cells | Cell Membrane - metabolism | Epithelial Cells - cytology | Cell Membrane - drug effects | Endocytosis - drug effects | beta Catenin - metabolism | Animals | Wnt Signaling Pathway - drug effects | Wnt Signaling Pathway - genetics | Dogs | Mesoderm - metabolism | Mice | Cytoplasm - drug effects | Regulators | Phosphorylation | Wnt protein | Transcription | Mesenchyme | Colorectal cancer | Activation | Biology | Cell adhesion & migration | Signal transduction | β-catenin | Embryogenesis | Endocytosis | Cell growth | Tumorigenesis | Trends | Growth factors | Chromosomes | Medical research | Gastrulation | Hepatocyte growth factor | Gene expression | Cadherin | Adhesion | Embryonic growth stage | Signaling | Insects | Morphology | Stem cells | Ligands | Mutation | Endoplasmic reticulum | Cytoplasm | Index Medicus
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 2013, Volume 202, Issue 5, pp. 747 - 763
Journal Article
Nature Immunology, ISSN 1529-2908, 06/2011, Volume 12, Issue 6, pp. 551 - 559
Journal Article
Cancer Letters, ISSN 0304-3835, 2012, Volume 330, Issue 1, pp. 22 - 32
Highlights ► Sonic hedgehog pathway regulates pancreatic cancer stem cell characteristics. ► Inhibition of Gli transcription by GANT-61 suppresses pancreatic... 
Hematology, Oncology and Palliative Medicine | Sonic hedgehog | Pancreatic cancer stem cells | Gli transcription factor | GANT-61 | SURVIVAL | METASTASIS | TUMOR PROGRESSION | GENOMIC ANALYSES | CARCINOMA PROLIFERATION | EPITHELIAL-MESENCHYMAL TRANSITIONS | GLI TRANSCRIPTION FACTORS | ONCOLOGY | MEDULLOBLASTOMA | TUMORIGENESIS | HEDGEHOG SIGNALING PATHWAY | RNA, Small Interfering - genetics | Pancreatic Neoplasms - metabolism | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Zinc Finger Protein Gli2 | Hedgehog Proteins - metabolism | Pancreatic Neoplasms - drug therapy | Transfection | Neoplastic Stem Cells - metabolism | HEK293 Cells | Neoplastic Stem Cells - pathology | Gene Expression Regulation, Neoplastic - drug effects | Nuclear Proteins - genetics | Cell Growth Processes - drug effects | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Pyrimidines - pharmacology | Transcription Factors - genetics | Down-Regulation - drug effects | Mice, SCID | Xenograft Model Antitumor Assays | Animals | Signal Transduction - drug effects | Cell Line, Tumor | Mice, Inbred NOD | Mice | Pyridines - pharmacology | Zinc Finger Protein GLI1 | RNA, Small Interfering - administration & dosage | Kruppel-Like Transcription Factors - genetics | Growth | Pancreatic cancer | Stem cells | Cell growth | Pancreas | Rodents | Cell cycle | Index Medicus
Journal Article
Endocrinology, ISSN 0013-7227, 10/2015, Volume 156, Issue 10, pp. 3804 - 3817
Growth factors modulate germ line stem cell self-renewal and differentiation behavior. We investigate the effects of Igf3, a fish-specific member of the igf... 
ANDROGEN RECEPTOR | STEM-CELLS | GERMLINE PROLIFERATION | RAINBOW-TROUT | UNDIFFERENTIATED SPERMATOGONIA | NEUROTROPHIC FACTOR | HORMONE RECEPTOR | ENDOCRINOLOGY & METABOLISM | BONY FISH | JAPANESE EEL | GROWTH-FACTOR-I | Receptor, IGF Type 1 - metabolism | Testis - metabolism | Zebrafish Proteins - pharmacology | Spermatogenesis - genetics | Gene Expression - drug effects | Humans | Male | Promoter Regions, Genetic - genetics | Sertoli Cells - drug effects | Spermatogonia - metabolism | Testis - drug effects | Follicle Stimulating Hormone - pharmacology | Cell Differentiation - genetics | Meiosis - drug effects | Somatomedins - pharmacology | HEK293 Cells | Spermatogonia - cytology | Follicle Stimulating Hormone - genetics | Somatomedins - metabolism | Sertoli Cells - metabolism | Spermatogonia - drug effects | Spermatogenesis - drug effects | Cell Proliferation - genetics | Testis - cytology | Animals, Genetically Modified | Tissue Culture Techniques | Zebrafish Proteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Receptor, IGF Type 1 - genetics | Zebrafish - genetics | Meiosis - genetics | Microscopy, Confocal | Animals | Cell Differentiation - drug effects | Somatomedins - genetics | Zebrafish - metabolism | Cell Proliferation - drug effects | Mutation | Zebrafish Proteins - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article