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European Journal of Organic Chemistry, ISSN 1434-193X, 12/2016, Volume 2016, Issue 34, pp. 5686 - 5696
Protein–protein interactions (PPIs) are involved in many cellular processes; consequently, the discovery of small molecules as modulators of PPIs has become an... 
Protein‐protein interactions | Protein models | Protein folding | Peptidomimetics | Molecular modeling | Protein-protein interactions | DESIGN | MOLECULE | HALOPYRIDINYLBORONIC ACIDS | CHEMISTRY, ORGANIC | CONFORMATION | OLIGOMERS | ESTERS | ALPHA-HELIX MIMETICS | INHIBITORS | SCAFFOLD | Organic chemistry | Chemical Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2009, Volume 106, Issue 35, pp. 14751 - 14756
Journal Article
Organic Letters, ISSN 1523-7060, 07/2018, Volume 20, Issue 13, pp. 3879 - 3882
The design and characterization of a proteomimetic foldamer that displays lateral flexibility endowed by intramolecular bifurcated hydrogen bonds is reported.... 
AMINO-ACID | DESIGN | PEPTIDES | SMALL MOLECULES | DRUG DISCOVERY | INTERFACES | CHEMISTRY, ORGANIC | PROTEIN-PROTEIN INTERACTIONS | ALPHA-HELIX MIMETICS | PROTEOMIMETICS | OLIGOMERS | Models, Molecular | Biomimetics | Hydrogen Bonding | Peptides | Molecular Conformation | Index Medicus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2012, Volume 134, Issue 38, pp. 15906 - 15913
The sophistication of folding patterns and functions displayed by unnatural-backbone oligomers has increased tremendously in recent years. Design strategies... 
BETA-AMINO ACIDS | AMINOMETHYLATION | NMR | HAIRPIN | STABILITY | AMINO | FOLDAMERS | B1 DOMAIN | QUATERNARY STRUCTURE | CHEMISTRY, MULTIDISCIPLINARY | HELIX MIMICRY | Amino Acid Sequence | Thermodynamics | Molecular Mimicry | Peptides - chemistry | Models, Molecular | Molecular Sequence Data | Nuclear Magnetic Resonance, Biomolecular | Proteins - chemistry | Index Medicus
Journal Article
Journal Article
RSC Advances, ISSN 2046-2069, 2014, Volume 4, Issue 41, pp. 21351 - 21360
We report the first application of NXO-pseudopeptides for beta-turn mimicry. Incorporating the proline-derived NProO peptidomimetic building block, a minimal... 
POLYPEPTIDE-CHAIN | SHEET FORMATION | TURN MIMICS | DE-NOVO DESIGN | ALPHA-HELIX | HAIRPIN PEPTIDE | CIS-TRANS ISOMERIZATION | AMINO-ACIDS | CHEMISTRY, MULTIDISCIPLINARY | SOLVABLE MODEL | HYDROGEN-BONDS | Molecular structure | Methyl alcohol | Amides | Mathematical models | Formations | Bonding | Folding | Mimicry
Journal Article
RSC Adv, ISSN 2046-2069, 2014, Volume 4, Issue 41, pp. 21351 - 21360
We report the first application of NXO-pseudopeptides for beta-turn mimicry. Incorporating the proline-derived NProO peptidomimetic building block, a minimal... 
Teknik och teknologier | TEKNIKVETENSKAP | Engineering and Technology | TECHNOLOGY
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 06/2013, Volume 1041, pp. 164 - 174
The molecular and crystal structure of a norbornane derivative decorated with isoxazoline and methylpyrolidine-2,5-dione ring, C H N O , were determined and... 
Helical chirality | DNA-mimetic | QTAIM | CSD search | Norbornane | Hirshfeld surface | ALPHA-HELIX | CAMBRIDGE STRUCTURAL DATABASE | RECOGNITION | AB-INITIO | CHEMISTRY, PHYSICAL | DENSITY | NITRILE OXIDES | 1,3-DIPOLAR CYCLOADDITION | MOLECULAR-CRYSTALS | CHEMISTRY | INTERMOLECULAR INTERACTIONS | DNA
Journal Article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, ISSN 1433-7851, 10/2018, Volume 57, Issue 42, pp. 13829 - 13832
Oligomers containing alpha- and beta-amino acid residues (alpha/beta-peptides) have been shown to mimic the alpha-helical conformation of conventional peptides... 
APOPTOSIS | DESIGN | DRUG DISCOVERY | peptides | circular dichroism | beta-amino acids | CHEMISTRY, MULTIDISCIPLINARY | protein-protein interactions | BH3 DOMAIN | AMINO-ACID | AFFINITY | FOLDAMERS | alpha-helix mimicry | INHIBITORS | HELIX MIMICRY
Journal Article
BIOPOLYMERS, ISSN 0006-3525, 05/2013, Volume 100, Issue 3, pp. 235 - 235
Conference Proceeding
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 5051 - 14
Many biomaterials utilize chiral growth to imitate biological functions. A prominent example can be found in growing cucumbers, which use tendrils as winding... 
ELASTICA | ROD | MULTIDISCIPLINARY SCIENCES | GROWTH | HELIX | LIE | PERVERSION | DEFORMATION | REVERSAL | Mechanical properties | Climbing | Mimicry | Biomaterials
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2015, Volume 54, Issue 37, pp. 10931 - 10934
We report the discovery of a peptide stapling and macrocyclization method using thiol–ene reactions between two cysteine residues and an α,ω‐diene in high... 
bioconjugation | peptide stapling | peptide macrocyclization | thiol–ene coupling | thiol-ene coupling | HELICITY | MIMICRY | INHIBITION | HELIX | CHEMISTRY, MULTIDISCIPLINARY | METATHESIS | P53 | Cyclization | Peptides - chemistry | Sulfhydryl Compounds - chemistry | Cysteine | Thiols | Peptides | Tumor proteins | Colorectal cancer | Index Medicus | Residues | Macrocyclic compounds | Stabilization | Blocking | Hydrocarbons | Joining | Helicity
Journal Article