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Blood, ISSN 0006-4971, 05/2012, Volume 119, Issue 21, pp. 4823 - 4837
Journal Article
Journal Article
International Journal of Developmental Biology, ISSN 0214-6282, 2010, Volume 54, Issue 6-7, pp. 1127 - 1137
Journal Article
Development, ISSN 0950-1991, 01/2007, Volume 134, Issue 2, pp. 393 - 405
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2007, Volume 104, Issue 45, pp. 17692 - 17697
Conservation of the vertebrate body plan has been attributed to the evolutionary stability of gene-regulatory networks (GRNs). We describe a regulatory circuit... 
Transgenic animals | Hematopoiesis | Blood cells | Stem cells | Cell lines | Transgenes | Embryos | Blood | Endothelial cells | Hematopoietic stem cells | Hemangioblast | Hematopoietic stem cell | Transcription factor network | Network motif | BMP | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTIONAL NETWORK | hematopoietic stem cell | ADULT | STEM-CELL ENHANCER | EMBRYONIC BLOOD | hematopoiesis | EVOLUTION | transcription factor network | ENDOTHELIAL-CELLS | MICE | DIFFERENTIATION | hemangioblast | EXPRESSION | network motif | Proto-Oncogene Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Proto-Oncogene Protein c-fli-1 - genetics | Gene Expression Regulation | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins - chemistry | GATA2 Transcription Factor - chemistry | Blood Vessels - embryology | Embryo, Mammalian - physiology | Animals | Basic Helix-Loop-Helix Transcription Factors - metabolism | Enhancer Elements, Genetic | Proto-Oncogene Protein c-fli-1 - metabolism | GATA2 Transcription Factor - metabolism | Hematopoietic Stem Cells - physiology | Proto-Oncogene Protein c-fli-1 - chemistry | Hematopoiesis - physiology | Mice | Blood Vessels - physiology | Binding Sites | GATA2 Transcription Factor - genetics | T-Cell Acute Lymphocytic Leukemia Protein 1 | Basic Helix-Loop-Helix Transcription Factors - chemistry | Genetic aspects | Hematopoietic system | DNA binding proteins | Properties | Biological Sciences
Journal Article
Blood, ISSN 0006-4971, 2013, Volume 122, Issue 24, pp. 3929 - 3939
The developmental relationship between the blood and endothelial cell (EC) lineages remains unclear. In the extra-embryonic blood islands of birds and mammals,... 
VASCULAR DEVELOPMENT | CELLS | ZEBRAFISH | PRIMITIVE HEMATOPOIESIS | GROWTH-FACTOR | HEMANGIOBLAST | HEMATOLOGY | COMMON PRECURSOR | MOUSE EMBRYO | MICE LACKING | XENOPUS EMBRYO | Bone Morphogenetic Proteins - antagonists & inhibitors | Embryo, Nonmammalian - cytology | Hemangioblasts - cytology | Xenopus Proteins - genetics | Hemangioblasts - metabolism | Embryo, Nonmammalian - metabolism | Embryo, Nonmammalian - embryology | Cell Movement - genetics | Gene Knockdown Techniques | Cell Differentiation - genetics | Bone Morphogenetic Proteins - metabolism | In Situ Hybridization | Gene Expression Regulation, Developmental | Xenopus laevis - genetics | Bone Morphogenetic Proteins - genetics | Hematopoietic System - embryology | Cell Lineage - genetics | Erythropoiesis - genetics | Pyrazoles - pharmacology | Erythroid Precursor Cells - cytology | Xenopus laevis - embryology | Animals, Genetically Modified | Endothelial Cells - metabolism | Signal Transduction - genetics | Pyrimidines - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Endothelium - embryology | Endothelium - cytology | Hematopoietic System - cytology | Animals | Hematopoietic System - metabolism | Endothelium - metabolism | Signal Transduction - drug effects | Endothelial Cells - cytology | Erythroid Precursor Cells - metabolism | Xenopus Proteins - metabolism | Microscopy, Fluorescence | Hematopoiesis and Stem Cells
Journal Article
Journal Article
International Journal of Developmental Biology, ISSN 0214-6282, 2010, Volume 54, Issue 6-7, pp. 1139 - 1149
Blood development has been highly conserved during evolution. Hematopoietic cells in amphibian and fish embryos, as in mammalian embryos, emerge and... 
Adult hematopoietic stem cell | Hemangioblast | Transcriptional regulation | Hematopoiesis
Journal Article
Journal Article
BLOOD, ISSN 0006-4971, 06/2012, Volume 119, Issue 23, pp. 5417 - 5428
Much remains unknown about the signals that induce early mesoderm to initiate hematopoietic differentiation. Here, we show that endoglin (Eng), a receptor for... 
SIGNAL-TRANSDUCTION | DEFINITIVE HEMATOPOIESIS | HEMANGIOBLAST DEVELOPMENT | PRIMITIVE ERYTHROPOIESIS | YOLK-SAC | HEMATOPOIETIC STEM-CELLS | ENDOTHELIAL-CELLS | BONE MORPHOGENETIC PROTEIN-4 | TGF-BETA RECEPTOR | HEMATOLOGY | MOUSE EMBRYO
Journal Article