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Blood, ISSN 0006-4971, 12/2012, Volume 120, Issue 26, pp. 5143 - 5152
Shwachman-Diamond syndrome (SDS) is an autosomal-recessive marrow failure syndrome with a predisposition to leukemia. SDS patients harbor biallelic mutations... 
YEAST | CELLS | EUKARYOTIC TRANSLATION INITIATION | BLACKFAN ANEMIA | GENE | P53 PROTEIN OVEREXPRESSION | BONE-MARROW | SBDS | HEMATOLOGY | SACCHAROMYCES-CEREVISIAE | HEMATOPOIETIC PROGENITORS | Exocrine Pancreatic Insufficiency - genetics | Exocrine Pancreatic Insufficiency - metabolism | Protein Binding - genetics | Stromal Cells - pathology | Humans | Lipomatosis - metabolism | Gene Knockdown Techniques | Hematopoiesis - drug effects | Transfection | Eukaryotic Initiation Factors - physiology | Lipomatosis - pathology | Protein Binding - drug effects | Protein Multimerization - physiology | Protein Multimerization - genetics | Stromal Cells - drug effects | Bone Marrow Cells - drug effects | Hematopoiesis - physiology | Infant, Newborn | Eukaryotic Initiation Factors - genetics | Eukaryotic Initiation Factors - metabolism | Proteins - physiology | Exocrine Pancreatic Insufficiency - pathology | RNA, Small Interfering - pharmacology | Stromal Cells - metabolism | Bone Marrow Cells - pathology | Cells, Cultured | Bone Marrow Diseases - metabolism | Hematopoiesis - genetics | Bone Marrow Diseases - pathology | Lipomatosis - genetics | Bone Marrow Diseases - genetics | Proteins - genetics | Proteins - metabolism | Bone Marrow Cells - metabolism | Protein Multimerization - drug effects | Ribosome Subunits - metabolism | Index Medicus | Abridged Index Medicus | Hematopoiesis and Stem Cells
Journal Article
2008, Volume 1, 1
Reference
Circulation, ISSN 0009-7322, 01/2019, Volume 139, Issue 1, pp. 7 - 9
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 2, pp. 111 - 121
Journal Article
Science, ISSN 0036-8075, 02/2017, Volume 355, Issue 6327, pp. 842 - 847
Journal Article
1989, Contemporary biomedicine., ISBN 9780896031470, xxii, 453
Book
Journal Article
EMBO reports, ISSN 1469-221X, 10/2018, Volume 19, Issue 10, pp. e45477 - n/a
Few studies report on the in vivo requirement for hematopoietic niche factors in the mammalian embryo. Here, we comprehensively analyze the requirement for Kit... 
embryo | hematopoiesis | niche | AGM | Kit ligand | TYROSINE KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-KIT | CELL BIOLOGY | AGM REGION | ERYTHRO-MYELOID PROGENITORS | DEFINITIVE HEMATOPOIESIS | MUTANT MICE | TISSUE-RESIDENT MACROPHAGES | STEM-CELL FACTOR | GROWTH-FACTOR | FETAL LIVER | Mesonephros - growth & development | Cell Proliferation - genetics | Endothelial Cells - metabolism | Embryonic Development - genetics | Gene Expression Regulation, Developmental - genetics | Hematopoiesis - genetics | Mice, Transgenic | Stem Cell Factor - genetics | Yolk Sac - growth & development | Aorta - growth & development | Animals | Endothelial Cells - cytology | Gonads - growth & development | Hematopoietic Stem Cells - cytology | Mice | Stem Cell Niche - genetics | Cell Lineage - genetics | Erythropoiesis - genetics | Cell proliferation | Erythropoiesis | Animal models | Leukocyte migration | Liver | Transgenic | Macrophages | Hematopoietic stem cells | Clonal deletion | Hematopoiesis | Rodents | Deletion | Aorta | Yolk | Phenotypes | Cell survival | Fetuses | Erythroid cells | Embryos | Endothelial cells | Hemopoiesis | Yolk sac | Hepatocytes | Coronary vessels | Stem cells | Ligands | In vivo methods and tests | Cell migration | Niches | Index Medicus | Stem Cells | Signal Transduction | Development & Differentiation
Journal Article
Science, ISSN 0036-8075, 09/2016, Volume 353, Issue 6304, pp. aaf4238 - aaf4238
Journal Article
2006, Medical intelligence unit, ISBN 9780306478727
Web Resource
Nature Cell Biology, ISSN 1465-7392, 07/2018, Volume 20, Issue 7, pp. 836 - 846
The dynamics of haematopoietic stem cell differentiation and the hierarchy of oligopotent stem cells in the bone marrow remain controversial. Here we dissect... 
LINEAGE-COMMITMENT | STEM-CELLS | RNA-SEQ | IN-VIVO | DYNAMICS | DIFFERENTIATION | MOUSE BONE-MARROW | IDENTIFICATION | PU.1 | HIERARCHY | CELL BIOLOGY | Erythropoietin - pharmacology | Interferon Regulatory Factors - metabolism | Transcriptome | Homeostasis | Hematopoiesis - drug effects | Time Factors | Single-Cell Analysis - methods | Trans-Activators - genetics | Hematopoietic Stem Cells - physiology | Female | CCAAT-Enhancer-Binding Proteins - genetics | Cell Lineage - genetics | CCAAT-Enhancer-Binding Proteins - metabolism | Hematopoietic Stem Cells - drug effects | Proto-Oncogene Proteins - metabolism | Cellular Senescence - genetics | Cell Proliferation - genetics | Hematinics - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Interferon Regulatory Factors - genetics | Gene Expression Profiling - methods | Genotype | Hematopoiesis - genetics | Proto-Oncogene Proteins - genetics | Hematopoietic Stem Cells - metabolism | Recombinant Proteins - pharmacology | Gene Editing | Phenotype | Animals | CRISPR-Cas Systems | Trans-Activators - metabolism | Filgrastim - pharmacology | Physiological aspects | Genetic aspects | Research | Hematopoiesis | Hematopoietic stem cells | Animal models | Populations | Transcription | Differentiation (biology) | Stem cell transplantation | Trajectories | Cell differentiation | Hemopoiesis | Monocytes | PU.1 protein | Perturbation methods | Stem cells | Bone marrow | Leukocytes (granulocytic) | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2018, Volume 24, Issue 2, pp. 239 - 246
There is a substantial unmet clinical need for new strategies to protect the hematopoietic stem cell (HSC) pool and regenerate hematopoiesis after radiation... 
PROGENITOR CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | HOMEOSTASIS | ACTIVATION | DEFECTS | REGENERATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUIESCENCE | SELF-RENEWAL | MICE | CELL BIOLOGY | Whole-Body Irradiation | Cell Self Renewal - radiation effects | Humans | Luteinizing Hormone - metabolism | Regeneration - radiation effects | Cell Self Renewal - drug effects | Hematopoiesis - drug effects | Cell Self Renewal - genetics | Hematopoiesis - radiation effects | Receptors, LH - genetics | Radiation Injuries, Experimental - drug therapy | Regeneration - genetics | Luteinizing Hormone - pharmacology | Signal Transduction - radiation effects | Hematopoietic Stem Cells - radiation effects | Radiation Injuries, Experimental - metabolism | Cell Differentiation - radiation effects | Hematopoietic Stem Cells - drug effects | Cell Proliferation - genetics | Cell Cycle - radiation effects | Hematopoiesis - genetics | Gonadotropin-Releasing Hormone - antagonists & inhibitors | Hematopoietic Stem Cells - metabolism | Radiation Injuries, Experimental - pathology | Regeneration - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Cell Proliferation - radiation effects | Care and treatment | Physiological aspects | Luteinizing hormone | Bone marrow | Genetic aspects | Research | Hematopoietic stem cells | Diseases | Lymphopoiesis | Sex | Radiation | Dimorphism | Hormones | Recovery | Lethal dose | Hematopoiesis | Rodents | Cell cycle | Radiation injuries | Inhibition | Sexual dimorphism | Hematology | Ablation | Radiation dosage | Hemopoiesis | Sex hormones | Regeneration | Exhaustion | Stem cells | Irradiation | Luteinizing hormone-releasing hormone | Steroid hormones | Steroids | Cancer | Index Medicus
Journal Article