Blood, ISSN 0006-4971, 04/2012, Volume 119, Issue 16, pp. 3815 - 3819
Diamond Blackfan anemia (DBA) is an inherited bone marrow failure syndrome characterized by red cell aplasia and congenital anomalies. A predisposition to...
MARROW FAILURE SYNDROMES | RISKS | NATURAL-HISTORY | HEMATOLOGY | FANCONI-ANEMIA | CANCER | Follow-Up Studies | Comorbidity | Bone Marrow Diseases | Humans | Middle Aged | Risk Factors | Child, Preschool | Neoplasms - mortality | Infant | Male | Anemia, Aplastic | Anemia, Diamond-Blackfan - mortality | Incidence | Young Adult | Registries - statistics & numerical data | Adolescent | Bone Marrow Transplantation | Anemia, Diamond-Blackfan - therapy | Adult | Female | Aged | Hemoglobinuria, Paroxysmal - therapy | Child | Hemoglobinuria, Paroxysmal - mortality | Clinical Trials and Observations | Red Cells, Iron, and Erythropoiesis
MARROW FAILURE SYNDROMES | RISKS | NATURAL-HISTORY | HEMATOLOGY | FANCONI-ANEMIA | CANCER | Follow-Up Studies | Comorbidity | Bone Marrow Diseases | Humans | Middle Aged | Risk Factors | Child, Preschool | Neoplasms - mortality | Infant | Male | Anemia, Aplastic | Anemia, Diamond-Blackfan - mortality | Incidence | Young Adult | Registries - statistics & numerical data | Adolescent | Bone Marrow Transplantation | Anemia, Diamond-Blackfan - therapy | Adult | Female | Aged | Hemoglobinuria, Paroxysmal - therapy | Child | Hemoglobinuria, Paroxysmal - mortality | Clinical Trials and Observations | Red Cells, Iron, and Erythropoiesis
Journal Article
Histopathology, ISSN 0309-0167, 03/2017, Volume 70, Issue 4, pp. 650 - 656
Aims A new subtype of granzyme B (GrB)‐producing regulatory B cells (Bregs) has been described recently; these peculiar cytotoxic B cells are increased...
EBV | granzyme B | DLBCL | HIV | Breg | cytotoxic | APOPTOSIS | INTERLEUKIN-21 | PATHOLOGY | IL-21 | CELL BIOLOGY | B-reg | HODGKINS-DISEASE | HIV-INFECTION | HUMAN NAIVE | DIFFERENTIATION | EXPRESSION | GRANZYME-B | T-CELLS | Coinfection | Lymphoma, Large B-Cell, Diffuse - pathology | Biomarkers, Tumor - analysis | Tissue Array Analysis | Epstein-Barr Virus Infections - immunology | Humans | Lymphoma, Large B-Cell, Diffuse - complications | Male | B-Lymphocytes, Regulatory - pathology | Epstein-Barr Virus Infections - pathology | In Situ Hybridization | HIV Infections - complications | Lymphoma, Large B-Cell, Diffuse - immunology | Epstein-Barr Virus Infections - complications | Aged | Granzymes - biosynthesis | Lymphomas | Epstein-Barr virus | B cells | Health aspects | HIV infection | Cytotoxicity | Infections | Genes | Human immunodeficiency virus--HIV
EBV | granzyme B | DLBCL | HIV | Breg | cytotoxic | APOPTOSIS | INTERLEUKIN-21 | PATHOLOGY | IL-21 | CELL BIOLOGY | B-reg | HODGKINS-DISEASE | HIV-INFECTION | HUMAN NAIVE | DIFFERENTIATION | EXPRESSION | GRANZYME-B | T-CELLS | Coinfection | Lymphoma, Large B-Cell, Diffuse - pathology | Biomarkers, Tumor - analysis | Tissue Array Analysis | Epstein-Barr Virus Infections - immunology | Humans | Lymphoma, Large B-Cell, Diffuse - complications | Male | B-Lymphocytes, Regulatory - pathology | Epstein-Barr Virus Infections - pathology | In Situ Hybridization | HIV Infections - complications | Lymphoma, Large B-Cell, Diffuse - immunology | Epstein-Barr Virus Infections - complications | Aged | Granzymes - biosynthesis | Lymphomas | Epstein-Barr virus | B cells | Health aspects | HIV infection | Cytotoxicity | Infections | Genes | Human immunodeficiency virus--HIV
Journal Article
Lipids, ISSN 0024-4201, 8/2014, Volume 49, Issue 8, pp. 807 - 818
In a previous study we compared lipid composition and functional parameters of circulating cells from Cerastoderma edule affected or not by disseminated...
Neurochemistry | Nutrition | Medical Biochemistry | Cell functions | Plasmalogens | Life Sciences | Medicinal Chemistry | Membrane lipids | Lipidology | Disseminated neoplasia | Microbial Genetics and Genomics | Mya arenaria | Hemocytes | PECTEN-MAXIMUS | COCKLES CERASTODERMA-EDULE | FATTY-ACID-COMPOSITION | CRASSOSTREA-GIGAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MARINE BIVALVES | MYTILUS-EDULIS | NUTRITION & DIETETICS | HEMIC NEOPLASIA | FLOW-CYTOMETRY | RUDITAPES-PHILIPPINARUM | Animals | Reactive Oxygen Species - metabolism | Mya - metabolism | Membrane Lipids - metabolism | Neoplasms - pathology | Hemocytes - metabolism | Phagocytosis | Mya - immunology | Physiological aspects | Properties | Neoplastic processes
Neurochemistry | Nutrition | Medical Biochemistry | Cell functions | Plasmalogens | Life Sciences | Medicinal Chemistry | Membrane lipids | Lipidology | Disseminated neoplasia | Microbial Genetics and Genomics | Mya arenaria | Hemocytes | PECTEN-MAXIMUS | COCKLES CERASTODERMA-EDULE | FATTY-ACID-COMPOSITION | CRASSOSTREA-GIGAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MARINE BIVALVES | MYTILUS-EDULIS | NUTRITION & DIETETICS | HEMIC NEOPLASIA | FLOW-CYTOMETRY | RUDITAPES-PHILIPPINARUM | Animals | Reactive Oxygen Species - metabolism | Mya - metabolism | Membrane Lipids - metabolism | Neoplasms - pathology | Hemocytes - metabolism | Phagocytosis | Mya - immunology | Physiological aspects | Properties | Neoplastic processes
Journal Article
Journal of Invertebrate Pathology, ISSN 0022-2011, 11/2018, Volume 159, pp. 1 - 5
Disseminated neoplasia (DN) is a disease that affects bivalves worldwide and can lead to mass mortalities. In the present study, a pathological survey...
Flow cytometry | Haemocytic leukemia | Reactive oxygen species | Histology | Population assessment | Phagocytosis | MUSSELS | CELLS | COCKLES CERASTODERMA-EDULE | MEMBRANE-LIPID COMPOSITION | IMMUNE | REACTIVE OXYGEN | DISEASES | ZOOLOGY | HEMIC NEOPLASIA | FUNCTIONAL PARAMETERS | BAY | Oysters | Crassostrea | Analysis | Leukemia | Life Sciences | Animal biology | Ecology, environment | Cellular Biology
Flow cytometry | Haemocytic leukemia | Reactive oxygen species | Histology | Population assessment | Phagocytosis | MUSSELS | CELLS | COCKLES CERASTODERMA-EDULE | MEMBRANE-LIPID COMPOSITION | IMMUNE | REACTIVE OXYGEN | DISEASES | ZOOLOGY | HEMIC NEOPLASIA | FUNCTIONAL PARAMETERS | BAY | Oysters | Crassostrea | Analysis | Leukemia | Life Sciences | Animal biology | Ecology, environment | Cellular Biology
Journal Article
Journal of Invertebrate Pathology, ISSN 0022-2011, 2010, Volume 104, Issue 2, pp. 110 - 118
The present report presents the first evidence of disseminated neoplasia (DN) in cockles from Arcachon Bay (France). Aneuploidy of neoplastic cells allowed the...
Flow cytometry | Disseminated neoplasia | Seasonal survey | Histology | DNA content | Cerastoderma edule | REVERSE-TRANSCRIPTASE ACTIVITY | HEMATOPOIETIC NEOPLASIA | MYA-ARENARIA | MYTILUS-EDULIS | COMMON COCKLE | BROWN MUSCLE DISEASE | ZOOLOGY | HEMIC NEOPLASIA | SOFT-SHELL CLAM | FLOW-CYTOMETRY | RUDITAPES-PHILIPPINARUM | Cardiidae - cytology | Animals | Neoplasms - genetics | Blood Cells - pathology | Disease Outbreaks - veterinary | Aneuploidy | Clone Cells | Seasons | France | Neoplasms - veterinary | Sea-water | Sediments (Geology) | Prevalence studies (Epidemiology) | Environmental Sciences
Flow cytometry | Disseminated neoplasia | Seasonal survey | Histology | DNA content | Cerastoderma edule | REVERSE-TRANSCRIPTASE ACTIVITY | HEMATOPOIETIC NEOPLASIA | MYA-ARENARIA | MYTILUS-EDULIS | COMMON COCKLE | BROWN MUSCLE DISEASE | ZOOLOGY | HEMIC NEOPLASIA | SOFT-SHELL CLAM | FLOW-CYTOMETRY | RUDITAPES-PHILIPPINARUM | Cardiidae - cytology | Animals | Neoplasms - genetics | Blood Cells - pathology | Disease Outbreaks - veterinary | Aneuploidy | Clone Cells | Seasons | France | Neoplasms - veterinary | Sea-water | Sediments (Geology) | Prevalence studies (Epidemiology) | Environmental Sciences
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2018, Volume 201, Issue 2, pp. 804 - 813
In mice, fetal/neonatal B-1 cell development generates murine CD5(+) B cells (B1a) with autoreactivity. We analyzed B1a cells at the neonatal stage in a...
ANTIBODIES | B-1 CELLS | TREATED MOUSE ERYTHROCYTES | POSITIVE SELECTION | COMMENSAL BACTERIA | CYCLIN D1 | CHRONIC LYMPHOCYTIC-LEUKEMIA | V-H GENES | IMMUNOLOGY | AUTOANTIBODY | EXPRESSION | Lymphocyte receptors | Neonates | Splenomegaly | Liver | Hyperplasia | Cyclin D1 | Lymph nodes | CD23 antigen | Intestine | Aging | CD43 antigen | Colon | Mantle | Spleen | CD11b antigen | Fetuses | Stat3 protein | Lymphoma | CD5 antigen | Thymocytes | Hepatocytes | Lymphocytes B | Mantle cell lymphoma | Interleukin 10 | Mice | Lymphomas | Lymphocytosis | Lymph | Tumor Immunology
ANTIBODIES | B-1 CELLS | TREATED MOUSE ERYTHROCYTES | POSITIVE SELECTION | COMMENSAL BACTERIA | CYCLIN D1 | CHRONIC LYMPHOCYTIC-LEUKEMIA | V-H GENES | IMMUNOLOGY | AUTOANTIBODY | EXPRESSION | Lymphocyte receptors | Neonates | Splenomegaly | Liver | Hyperplasia | Cyclin D1 | Lymph nodes | CD23 antigen | Intestine | Aging | CD43 antigen | Colon | Mantle | Spleen | CD11b antigen | Fetuses | Stat3 protein | Lymphoma | CD5 antigen | Thymocytes | Hepatocytes | Lymphocytes B | Mantle cell lymphoma | Interleukin 10 | Mice | Lymphomas | Lymphocytosis | Lymph | Tumor Immunology
Journal Article
Journal of Fish Diseases, ISSN 0140-7775, 09/2016, Volume 39, Issue 9, pp. 1027 - 1042
The dynamics of disseminated neoplasia (DN) affecting cockles Cerastoderma edule (L.) in Galicia was addressed at individual and population levels. Early stage...
gonad condition | mortality | epidemiology | environmental factors | seasonality | sex | Environmental factors | Gonad condition | Epidemiology | Mortality | Seasonality | Sex | CHESAPEAKE BAY | MYA-ARENARIA | MYTILUS-EDULIS | CERASTODERMA-EDULE | FISHERIES | EPIZOOTIOLOGICAL ASPECTS | MARINE & FRESHWATER BIOLOGY | HEMIC NEOPLASIA | CRASSOSTREA-VIRGINICA | VETERINARY SCIENCES | SOFT-SHELL CLAM | FLOW-CYTOMETRY | REPRODUCTIVE-CYCLE | Environment | Animals | Cardiidae - physiology | Seasons | Spain | Environmental aspects
gonad condition | mortality | epidemiology | environmental factors | seasonality | sex | Environmental factors | Gonad condition | Epidemiology | Mortality | Seasonality | Sex | CHESAPEAKE BAY | MYA-ARENARIA | MYTILUS-EDULIS | CERASTODERMA-EDULE | FISHERIES | EPIZOOTIOLOGICAL ASPECTS | MARINE & FRESHWATER BIOLOGY | HEMIC NEOPLASIA | CRASSOSTREA-VIRGINICA | VETERINARY SCIENCES | SOFT-SHELL CLAM | FLOW-CYTOMETRY | REPRODUCTIVE-CYCLE | Environment | Animals | Cardiidae - physiology | Seasons | Spain | Environmental aspects
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 11/2007, Volume 150, Issue 2, pp. 199 - 209
Summary Oncogenic human papillomavirus (HPV)-infection is crucial for developing cervical cancer and its precursor lesions [cervical intraepithelial neoplasia...
regulatory T cells | CD4+ T cell | CD8+ T cell | cervical cancer | HPV | HUMAN-PAPILLOMAVIRUS TYPE-16 | CD8(+) T cell | INCREASED POPULATIONS | PERIPHERAL-BLOOD | INDUCTION | UMCG Approved | DRAINING LYMPH-NODES | TUMOR-INFILTRATING LYMPHOCYTES | RESPONSES | CANCER-PATIENTS | CD4(+) | ANTITUMOR IMMUNITY | CD4(+) T cell | CD4 | Regulatory T cells | T cell | CD8 | Cervical cancer | IMMUNOLOGY | Follow-Up Studies | Humans | Middle Aged | Uterine Cervical Neoplasms - immunology | Immunophenotyping | Papillomavirus E7 Proteins | Disease Progression | Cervical Intraepithelial Neoplasia - virology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Human papillomavirus 16 - isolation & purification | Cervical Intraepithelial Neoplasia - therapy | Forkhead Transcription Factors - blood | Repressor Proteins - immunology | Papillomavirus Infections - immunology | Uterine Cervical Neoplasms - virology | Adult | Female | Oncogene Proteins, Viral - immunology | Cervical Intraepithelial Neoplasia - immunology | Cytokines - biosynthesis | Uterine Cervical Neoplasms - therapy | Microbiology | T cells | Translational Studies
regulatory T cells | CD4+ T cell | CD8+ T cell | cervical cancer | HPV | HUMAN-PAPILLOMAVIRUS TYPE-16 | CD8(+) T cell | INCREASED POPULATIONS | PERIPHERAL-BLOOD | INDUCTION | UMCG Approved | DRAINING LYMPH-NODES | TUMOR-INFILTRATING LYMPHOCYTES | RESPONSES | CANCER-PATIENTS | CD4(+) | ANTITUMOR IMMUNITY | CD4(+) T cell | CD4 | Regulatory T cells | T cell | CD8 | Cervical cancer | IMMUNOLOGY | Follow-Up Studies | Humans | Middle Aged | Uterine Cervical Neoplasms - immunology | Immunophenotyping | Papillomavirus E7 Proteins | Disease Progression | Cervical Intraepithelial Neoplasia - virology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Human papillomavirus 16 - isolation & purification | Cervical Intraepithelial Neoplasia - therapy | Forkhead Transcription Factors - blood | Repressor Proteins - immunology | Papillomavirus Infections - immunology | Uterine Cervical Neoplasms - virology | Adult | Female | Oncogene Proteins, Viral - immunology | Cervical Intraepithelial Neoplasia - immunology | Cytokines - biosynthesis | Uterine Cervical Neoplasms - therapy | Microbiology | T cells | Translational Studies
Journal Article
Clinical and Translational Oncology, ISSN 1699-048X, 2/2013, Volume 15, Issue 2, pp. 87 - 94
MYC is a transcription factor that regulates many critical genes for cell proliferation, differentiation, and biomass accumulation. MYC is one of the most...
Medicine & Public Health | MYC | Oncology | Myeloid neoplasia | Chronic myeloid leukemia | Acute myeloid leukemia | Myelodysplastic syndromes | CHRONIC MYELOGENOUS LEUKEMIA | BCR-ABL | IN-SITU HYBRIDIZATION | C-MYC | MYELODYSPLASTIC SYNDROME | DOUBLE MINUTE CHROMOSOMES | MOLECULAR SIGNATURE | B-CELL LYMPHOMA | ONCOLOGY | DEREGULATED EXPRESSION | TRANSGENIC MICE | Myelodysplastic Syndromes - genetics | Animals | Genes, myc - genetics | Humans | Leukemia, Myeloid - genetics | Lymphomas | Genetic aspects | Genetic transcription | Analysis | Leukemia
Medicine & Public Health | MYC | Oncology | Myeloid neoplasia | Chronic myeloid leukemia | Acute myeloid leukemia | Myelodysplastic syndromes | CHRONIC MYELOGENOUS LEUKEMIA | BCR-ABL | IN-SITU HYBRIDIZATION | C-MYC | MYELODYSPLASTIC SYNDROME | DOUBLE MINUTE CHROMOSOMES | MOLECULAR SIGNATURE | B-CELL LYMPHOMA | ONCOLOGY | DEREGULATED EXPRESSION | TRANSGENIC MICE | Myelodysplastic Syndromes - genetics | Animals | Genes, myc - genetics | Humans | Leukemia, Myeloid - genetics | Lymphomas | Genetic aspects | Genetic transcription | Analysis | Leukemia
Journal Article
Neoplasia, ISSN 1476-5586, 2011, Volume 13, Issue 11, pp. 1058 - 1068
Abstract We recently developed a Janus kinase 2 (Jak2) small-molecule inhibitor called G6 and found that it inhibits Jak2-V617F– mediated pathologic cell...
Oncology | RESVERATROL | CELLS | POLYCYTHEMIA-VERA | IN-VITRO | RISK-FACTORS | ONCOLOGY | THROMBOSIS | IDIOPATHIC MYELOFIBROSIS | AGNOGENIC MYELOID METAPLASIA | DISORDERS | ESSENTIAL THROMBOCYTHEMIA | Stilbenes - therapeutic use | Male | Antineoplastic Agents - therapeutic use | Myeloproliferative Disorders - pathology | Stilbenes - pharmacology | Bone Marrow Neoplasms - genetics | Myeloproliferative Disorders - genetics | Cell Transformation, Neoplastic - genetics | Bone Marrow Cells - drug effects | Antineoplastic Agents - pharmacology | Drug Evaluation, Preclinical | Janus Kinase 2 - antagonists & inhibitors | Mice, Inbred C57BL | Bone Marrow Cells - pathology | Cells, Cultured | Janus Kinase 2 - genetics | Mice, Transgenic | Myeloproliferative Disorders - drug therapy | Animals | Bone Marrow Neoplasms - pathology | Amino Acid Substitution - physiology | Phenylalanine - genetics | Protein Kinase Inhibitors - therapeutic use | Valine - genetics | Bone Marrow Neoplasms - drug therapy | Mice | Protein Kinase Inhibitors - pharmacology | Bone Marrow Cells - metabolism
Oncology | RESVERATROL | CELLS | POLYCYTHEMIA-VERA | IN-VITRO | RISK-FACTORS | ONCOLOGY | THROMBOSIS | IDIOPATHIC MYELOFIBROSIS | AGNOGENIC MYELOID METAPLASIA | DISORDERS | ESSENTIAL THROMBOCYTHEMIA | Stilbenes - therapeutic use | Male | Antineoplastic Agents - therapeutic use | Myeloproliferative Disorders - pathology | Stilbenes - pharmacology | Bone Marrow Neoplasms - genetics | Myeloproliferative Disorders - genetics | Cell Transformation, Neoplastic - genetics | Bone Marrow Cells - drug effects | Antineoplastic Agents - pharmacology | Drug Evaluation, Preclinical | Janus Kinase 2 - antagonists & inhibitors | Mice, Inbred C57BL | Bone Marrow Cells - pathology | Cells, Cultured | Janus Kinase 2 - genetics | Mice, Transgenic | Myeloproliferative Disorders - drug therapy | Animals | Bone Marrow Neoplasms - pathology | Amino Acid Substitution - physiology | Phenylalanine - genetics | Protein Kinase Inhibitors - therapeutic use | Valine - genetics | Bone Marrow Neoplasms - drug therapy | Mice | Protein Kinase Inhibitors - pharmacology | Bone Marrow Cells - metabolism
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 05/2011, Volume 131, Issue 5, pp. 1149 - 1158
Deregulation of the activator protein 1 (AP1) family gene regulators has been implicated in a wide range of diseases, including cancer. In this study we report...
MOUSE DEVELOPMENT | AP-1 SUBUNITS | DNA-BINDING | DELETION MUTANT | INDUCED TRANSFORMATION | SQUAMOUS-CELL CARCINOMA | TUMOR-FORMATION | PROLIFERATION | EXPRESSION | SKIN TUMORS | DERMATOLOGY | Skin Neoplasms - pathology | Up-Regulation | Skin - metabolism | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Down-Regulation | Humans | Male | Cyclin-Dependent Kinase 4 - metabolism | Neoplasm Proteins - metabolism | Transcription Factor AP-1 - metabolism | Oncogene Protein p21(ras) - metabolism | Cyclin-Dependent Kinase Inhibitor p16 | Skin Neoplasms - metabolism | Animals | Cellular Senescence | Proto-Oncogene Proteins c-jun - metabolism | Skin Transplantation - pathology | Cell Differentiation | Mice | Cell Culture Techniques | Intermediate Filament Proteins - metabolism | JunB | AP1 | c-Jun and squamous cell carcinoma
MOUSE DEVELOPMENT | AP-1 SUBUNITS | DNA-BINDING | DELETION MUTANT | INDUCED TRANSFORMATION | SQUAMOUS-CELL CARCINOMA | TUMOR-FORMATION | PROLIFERATION | EXPRESSION | SKIN TUMORS | DERMATOLOGY | Skin Neoplasms - pathology | Up-Regulation | Skin - metabolism | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Down-Regulation | Humans | Male | Cyclin-Dependent Kinase 4 - metabolism | Neoplasm Proteins - metabolism | Transcription Factor AP-1 - metabolism | Oncogene Protein p21(ras) - metabolism | Cyclin-Dependent Kinase Inhibitor p16 | Skin Neoplasms - metabolism | Animals | Cellular Senescence | Proto-Oncogene Proteins c-jun - metabolism | Skin Transplantation - pathology | Cell Differentiation | Mice | Cell Culture Techniques | Intermediate Filament Proteins - metabolism | JunB | AP1 | c-Jun and squamous cell carcinoma
Journal Article
Cancer Research, ISSN 0008-5472, 06/2009, Volume 69, Issue 11, pp. 4784 - 4790
LMO2 is a transcription regulator involved in human T-cell leukemia, including some occurring in X-SCID gene therapy trials, and in B-cell lymphomas and...
DOMAIN | ACTIVATION | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | LMO4-LDB1 COMPLEX | GENE-THERAPY | LIM-PROTEIN RBTN2 | EXPRESSION | BINDING | CHROMOSOMAL TRANSLOCATION | TRANSGENIC MICE | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Protein Binding - genetics | Cricetulus | Metalloproteins - physiology | Humans | Molecular Sequence Data | DNA-Binding Proteins - metabolism | Metalloproteins - metabolism | Protein Interaction Domains and Motifs - genetics | Metalloproteins - genetics | Tumor Cells, Cultured | Aptamers, Peptide - metabolism | CHO Cells | Amino Acid Sequence | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Cricetinae | DNA-Binding Proteins - physiology | Metalloproteins - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | LIM Domain Proteins | Models, Molecular | Mice, Transgenic | DNA-Binding Proteins - genetics | Adaptor Proteins, Signal Transducing | Animals | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Aptamers, Peptide - pharmacology | Aptamers, Peptide - therapeutic use | Zinc Fingers - genetics | Mice | Zinc Fingers - physiology | Drug Delivery Systems - methods | leukemia | LIM domain | therapy | LMO2 | chromosomal translocations | cancer | peptide aptamers
DOMAIN | ACTIVATION | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | LMO4-LDB1 COMPLEX | GENE-THERAPY | LIM-PROTEIN RBTN2 | EXPRESSION | BINDING | CHROMOSOMAL TRANSLOCATION | TRANSGENIC MICE | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Protein Binding - genetics | Cricetulus | Metalloproteins - physiology | Humans | Molecular Sequence Data | DNA-Binding Proteins - metabolism | Metalloproteins - metabolism | Protein Interaction Domains and Motifs - genetics | Metalloproteins - genetics | Tumor Cells, Cultured | Aptamers, Peptide - metabolism | CHO Cells | Amino Acid Sequence | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Cricetinae | DNA-Binding Proteins - physiology | Metalloproteins - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | LIM Domain Proteins | Models, Molecular | Mice, Transgenic | DNA-Binding Proteins - genetics | Adaptor Proteins, Signal Transducing | Animals | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Aptamers, Peptide - pharmacology | Aptamers, Peptide - therapeutic use | Zinc Fingers - genetics | Mice | Zinc Fingers - physiology | Drug Delivery Systems - methods | leukemia | LIM domain | therapy | LMO2 | chromosomal translocations | cancer | peptide aptamers
Journal Article