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Molecular Biology of the Cell, ISSN 1059-1524, 01/2019, Volume 30, Issue 2, pp. 201 - 208
Phosphoinositides (PIs) regulate a myriad of cellular functions including membrane fusion, as exemplified by the yeast vacuole, which uses various PIs at... 
V-ATPASE | RECRUITMENT | PROTEIN | YEAST VACUOLE | SEC18P | ALPHA-SNAP | REQUIRES | IDENTIFICATION | MORPHOLOGY | HEMIFUSION | CELL BIOLOGY | Brief Reports
Journal Article
Biophysical Journal, ISSN 0006-3495, 06/2017, Volume 112, Issue 11, pp. 2348 - 2356
In vitro single-vesicle fusion assays are important tools to analyze the details of SNARE-mediated fusion processes. In this study, we employed planar... 
SYNAPTIC VESICLES | IN-VITRO | BIOPHYSICS | FLUORESCENCE | EXOCYTOSIS | NEURONAL SNARES | COMPLEXES | POLARIZED TIRFM | DRIVEN | PROTEINS | HEMIFUSION
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 06/2014, Volume 1838, Issue 6, pp. 1529 - 1535
Membrane fusion is essential for intracellular trafficking and virus infection, but the molecular mechanisms underlying the fusion process remain poorly... 
Membrane fusion | Hemifusion diaphragm | Multi-step event | Energy landscape | Hemifusion diaphragm thinning | PROTEIN | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | MEMBRANE-FUSION | BIOPHYSICS | PHOSPHOLIPID-BILAYERS | LIPIDS
Journal Article
Journal of Cell Science, ISSN 0021-9533, 02/2019, Volume 132, Issue 4, p. jcs218321
Although influenza kills about a half million people each year, even after excluding pandemics, there is only one set of antiviral drugs: neuraminidase... 
Virus | Membrane | Spontaneous curvature | Poration | Fusion | HEMAGGLUTININ | PERMEABILITY | MECHANISM | EXOCYTOSIS | BILAYER-MEMBRANES | ENVELOPED VIRUSES | PORE FORMATION | MOLECULES | CELL BIOLOGY | TRANSITION | HEMIFUSION
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2016, Volume 138, Issue 13, pp. 4512 - 4521
Membrane fusion is mediated by the SNARE complex which is formed through a zippering process. Here, we developed a chemical controller for the progress of... 
SYNAPTIC VESICLES | COMPLEX | SINGLE-MOLECULE | NEUROTRANSMITTER RELEASE | SYNAPTOTAGMIN | MACHINERY | DYNAMICS | INTERMEDIATE | PROTEINS | CHEMISTRY, MULTIDISCIPLINARY | HEMIFUSION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 46, pp. 13051 - 13056
Fusion of lipid bilayers is usually prevented by large energy barriers arising from removal of the hydration shell, formation of highly curved structures, and,... 
Hydration barrier | AFM | Membrane fusion | Force spectroscopy | SNARE | COMPLEX | EVENTS | hydration barrier | VESICLES | MULTIDISCIPLINARY SCIENCES | ENERGETICS | PORE FORMATION | BILAYERS | MICROSCOPY | membrane fusion | PROTEIN INTERACTIONS | force spectroscopy | LIPID-COMPOSITION | HEMIFUSION | Biological Sciences
Journal Article
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7682, pp. 634 - 638
Journal Article
Frontiers in Molecular Neuroscience, ISSN 1662-5099, 03/2017, Volume 10, p. 93
Neurotransmitters are released within a millisecond after Ca2+ arrives at an active zone. However, the vesicle fusion pathway underlying this synchronous... 
Membrane fusion | Neurotransmitter release | Calcium | Myricetin | Hemifusion | SNARE | TOMOGRAPHY | CELLS | COMPLEX | ZIPPER | calcium | hemifusion | EXOCYTOSIS | MECHANISM | DRIVEN MEMBRANE-FUSION | RELEASE | neurotransmitter release | NEUROSCIENCES | membrane fusion | myricetin | FISSION | Neurotransmitters | Research | Liposomes
Journal Article
by Hu, B and Hofer, CT and Thiele, C and Veit, M
JOURNAL OF VIROLOGY, ISSN 0022-538X, 08/2019, Volume 93, Issue 15
Hemagglutinin (HA) of influenza virus is incorporated into cholesterol-enriched nanodomains of the plasma membrane. Phylogenetic group 2 HAs contain the... 
CYTOPLASMIC TAIL | ACYLATION SITES | MEMBRANE DOMAINS | INTRACELLULAR-TRANSPORT | hemagglutinin | PROMOTES HEMIFUSION | transmembrane region | virus assembly | QUANTITATIVE-ANALYSIS | LIPID INTERACTIONS | membrane fusion | CELL BIOLOGY | A VIRUS | VIROLOGY | S-ACYLATION | influenza virus | cholesterol
Journal Article
Journal Article
Current Opinion in Structural Biology, ISSN 0959-440X, 04/2012, Volume 22, Issue 2, pp. 187 - 196
► Molecular simulations have revisited the original stalk-pore hypothesis. ► Initial membrane merger is determined by the free energy of leaflet approach. ►... 
VESICLE FUSION | COMPLEX | PROTEIN | C-TERMINUS | MECHANISM | BILAYER-MEMBRANES | BIOCHEMISTRY & MOLECULAR BIOLOGY | FORCE-FIELD | MODEL | ENERGY BARRIERS | HEMIFUSION | CELL BIOLOGY | SNARE Proteins - chemistry | Membrane Fusion | Protein Binding | Lipid Bilayers - chemistry | Lipid Bilayers - metabolism | SNARE Proteins - metabolism | Molecular Dynamics Simulation
Journal Article