X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
hept (99) 99
1--6- (81) 81
chemistry, medicinal (78) 78
analogs (76) 76
humans (63) 63
potent (63) 63
derivatives (59) 59
anti-hiv-1 activity (57) 57
chemistry, multidisciplinary (54) 54
chemistry, organic (52) 52
hept derivatives (52) 52
immunodeficiency-virus type-1 (50) 50
reverse transcriptase inhibitors - pharmacology (47) 47
anti-hiv agents - pharmacology (46) 46
hiv-1 - drug effects (46) 46
structure-activity relationship (44) 44
reverse transcriptase inhibitors - chemistry (43) 43
biochemistry & molecular biology (42) 42
qsar (42) 42
anti-hiv agents - chemistry (41) 41
pharmacology & pharmacy (41) 41
quantitative structure-activity relationship (41) 41
antiviral activity (40) 40
hiv reverse transcriptase - antagonists & inhibitors (40) 40
hiv (39) 39
nonnucleoside inhibitors (39) 39
reverse-transcriptase inhibitors (37) 37
anti-hiv activity (36) 36
chemistry (35) 35
drug design (35) 35
index medicus (33) 33
thymine - analogs & derivatives (32) 32
hiv-1 (31) 31
computer science, interdisciplinary applications (29) 29
models, molecular (29) 29
analysis (28) 28
inhibitors (27) 27
molecular structure (27) 27
thymine - pharmacology (27) 27
neural networks (25) 25
thymine - chemistry (25) 25
anti-hiv agents - chemical synthesis (24) 24
design (24) 24
cell line (23) 23
reverse-transcriptase (23) 23
anti-hiv-1 agents (22) 22
series (22) 22
uracil - analogs & derivatives (22) 22
reverse transcriptase inhibitors - chemical synthesis (20) 20
uracil - pharmacology (20) 20
selective anti-hiv-1 agents (19) 19
agents (18) 18
algorithms (18) 18
animals (18) 18
antiviral agents - pharmacology (18) 18
hiv-1 - enzymology (18) 18
neural-networks (18) 18
organic chemistry (17) 17
reverse transcriptase (17) 17
selective-inhibition (17) 17
hiv reverse transcriptase - metabolism (15) 15
aids (14) 14
antiviral agents (14) 14
antiviral agents - chemistry (14) 14
hiv-1 reverse-transcriptase (13) 13
mkc-442 (13) 13
physical chemistry (13) 13
uracil - chemical synthesis (13) 13
deoxy analogs (12) 12
hiv reverse transcriptase - chemistry (12) 12
human-immunodeficiency-virus (12) 12
pyrimidines (12) 12
tibo (12) 12
dna polymerases (11) 11
nnrtis (11) 11
non-nucleoside reverse transcriptase inhibitors (11) 11
nucleosides (11) 11
uracil - chemistry (11) 11
virus replication - drug effects (11) 11
6-substituted acyclouridine derivatives (10) 10
anti-hiv (10) 10
binding (10) 10
biophysics (10) 10
chemistry, analytical (10) 10
computer simulation (10) 10
models (10) 10
protein binding (10) 10
regression analysis (10) 10
replication (10) 10
resistance (10) 10
reverse transcriptase inhibitors (10) 10
analytical chemistry (9) 9
binding sites (9) 9
drugs (9) 9
hept analogues (9) 9
highly potent (9) 9
hiv infections - drug therapy (9) 9
hiv-1 replication (9) 9
inhibition (9) 9
linear models (9) 9
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (251) 251
French (3) 3
German (3) 3
Chinese (2) 2
Japanese (1) 1
Russian (1) 1
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Organic Letters, ISSN 1523-7060, 04/2007, Volume 9, Issue 9, pp. 1639 - 1641
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 01/2014, Volume 51, Issue 1, pp. 277 - 281
A series of pyrido[2,3‐d][6,5‐d]dipyrimidine and 5,5′‐arylmethylenebis(2,6‐diaminopyrimidinone) derivatives have been synthesized through a rapid reaction of... 
ANTITUMOR AGENTS | HEPT | DIHYDROFOLATE REDUCTASES | PNEUMOCYSTIS-CARINII | ANALOGS | CRYSTAL-STRUCTURE | PYRIMIDINES | CHEMISTRY | CHEMISTRY, ORGANIC | TOXOPLASMA-GONDII | INHIBITORS
Journal Article
Journal Article
Journal Article
Chemical Biology & Drug Design, ISSN 1747-0277, 09/2011, Volume 78, Issue 3, pp. 418 - 426
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 1/2015, Volume 24, Issue 1, pp. 220 - 225
As a continuing and exploratory work on diarylpyrimidines (DAPYs) as human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) inhibitors, bulky... 
Biochemistry, general | HIV-1 | Biomedicine | Diarylpyrimidines | Reverse transcriptase inhibitors | Pharmacology/Toxicology | Cell Biology | DAPY ANALOGS | CHEMISTRY, MEDICINAL | COLORIMETRIC ASSAY | NNRTIS | ANTI-HIV-1 ACTIVITY | DRUG CANDIDATES | HEPT ANALOGS | DISCOVERY | POTENT | EVOLUTION | BENZOPHENONES | Drugstores | DNA polymerases | HIV (Viruses) | Pharmacy | Green technology
Journal Article
Chinese Journal of Chemical Engineering, ISSN 1004-9541, 10/2016, Volume 24, Issue 10, pp. 1464 - 1469
The search and development of anti-HIV drugs is currently one of the most urgent tasks of pharmacological studies. In this work, a quantitative... 
Mathematical modeling | HEPT derivatives | Anti-HIV-1 activity | Structure–activity relationship | Prediction | Pharmaceuticals
Journal Article
by Shahid, K and Wang, Q and Jia, QZ and Li, L and Cui, X and Xia, SQ and Ma, PS
CHINESE JOURNAL OF CHEMICAL ENGINEERING, ISSN 1004-9541, 10/2016, Volume 24, Issue 10, pp. 1464 - 1469
The search and development of anti-HIV drugs is currently one of the most urgent tasks of pharmacological studies. In this work, a quantitative... 
REGRESSION | ANTI-HIV-1 ACYCLONUCLEOSIDES | HEPT derivatives | STRUCTURE-PROPERTY | Prediction | VALIDATION | DEOXY ANALOGS | RELIABILITY | ENGINEERING, CHEMICAL | INHIBITION | ANTI-HIV ACTIVITY | Structure-activity relationship | Anti-HIV-1 activity | IMMUNODEFICIENCY-VIRUS TYPE-1 | Mathematical modeling | SELECTION | Pharmaceuticals
Journal Article
Journal Article
by Tong, J and Zhao, X and Zhong, L and Chang, J
Journal of Structural Chemistry, ISSN 0022-4766, 9/2015, Volume 56, Issue 5, pp. 857 - 864
Journal Article
Journal of the Chemical Society of Pakistan, ISSN 0253-5106, 2018, Volume 40, Issue 1, pp. 24 - 32
Quantitative structure-activity relationships were constructed for 107 inhibitors of HIV-1 reverse transcriptase that are derivatives of... 
HEPT | Features Selection | SVM | HIV | QSAR | REGRESSION | ANTI-HIV ACTIVITY | SELECTION | CHEMISTRY, MULTIDISCIPLINARY | BASIS FUNCTION NETWORKS | Usage | Reverse transcriptase inhibitors | Models | Algorithms | Research | Chemical research
Journal Article
Journal of Computational Chemistry, ISSN 0192-8651, 04/2009, Volume 30, Issue 6, pp. 922 - 933
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 1/2013, Volume 22, Issue 1, pp. 392 - 400
Journal Article