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Ophthalmology (Rochester, Minn.), ISSN 0161-6420, 03/2016, Volume 123, Issue 3, pp. 558 - 570
Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Electroretinography | Dependovirus - genetics | Genetic Therapy | Prospective Studies | Intravitreal Injections | Tomography, Optical Coherence | Humans | Middle Aged | Male | NADH Dehydrogenase - genetics | Optic Atrophy, Hereditary, Leber - genetics | Optic Atrophy, Hereditary, Leber - therapy | DNA, Mitochondrial - genetics | Visual Fields | Polymerase Chain Reaction | Adult | Female | Polymorphism, Single Nucleotide | Visual Field Tests | Genetic Vectors | Optic Atrophy, Hereditary, Leber - physiopathology | Visual Acuity - physiology | Genetic vectors | Gene therapy | Genes | Index Medicus
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Gene Therapy for Leber Hereditary Optic Neuropathy: Low- and Medium-Dose Visual Results
Ophthalmology (Rochester, Minn.), ISSN 0161-6420, 11/2017, Volume 124, Issue 11, pp. 1621 - 1634
Dependovirus - genetics | Genetic Therapy | Visual Fields - physiology | Prospective Studies | Follow-Up Studies | Intravitreal Injections | Humans | Middle Aged | Male | NADH Dehydrogenase - genetics | Retinal Ganglion Cells | Young Adult | DNA, Mitochondrial - genetics | Adult | Female | Optic Atrophy, Hereditary, Leber - physiopathology | Real-Time Polymerase Chain Reaction | Visual Acuity - physiology | Electroretinography | Tomography, Optical Coherence | Dependovirus - immunology | Optic Atrophy, Hereditary, Leber - therapy | Genetic Vectors | Nerve Fibers | Antibodies, Neutralizing - blood | Care and treatment | Genetic vectors | Gene therapy | Genes | Analysis | Blindness | Index Medicus
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Progress in retinal and eye research, ISSN 1350-9462, 03/2011, Volume 30, Issue 2, pp. 81 - 114
Glaucoma | Hereditary spastic paraplegia | Dominant optic atrophy | Neuroprotection | Multiple sclerosis | Mitofusin | Optic neuropathy | Optic neuritis | Leber hereditary optic neuropathy | Mitochondrial DNA | Retinal ganglion cell | Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Optic Nerve - pathology | Humans | Optic Atrophy, Hereditary, Leber - therapy | Retinal Ganglion Cells - pathology | Point Mutation | Optic Atrophy, Hereditary, Leber - pathology | Phenotype | Animals | DNA, Mitochondrial - genetics | Optic Atrophy, Autosomal Dominant - therapy | Optic Atrophy, Autosomal Dominant - pathology | Optic Atrophy, Autosomal Dominant - physiopathology | Optic Atrophy, Hereditary, Leber - physiopathology | Disease Models, Animal | Index Medicus
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Ophthalmology (Rochester, Minn.), ISSN 0161-6420, 06/2017, Volume 124, Issue 6, pp. 843 - 850
Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Nerve Fibers - pathology | Visual Fields - physiology | Prospective Studies | Tomography, Optical Coherence | Humans | Middle Aged | Male | Optic Atrophy, Hereditary, Leber - genetics | Retinal Ganglion Cells - pathology | Young Adult | Vision Disorders - diagnosis | Vision Disorders - physiopathology | DNA, Mitochondrial - genetics | Pedigree | Adolescent | Adult | Female | Visual Field Tests | Optic Atrophy, Hereditary, Leber - diagnosis | Visual Acuity - physiology | Index Medicus
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JAMA ophthalmology, ISSN 2168-6165, 02/2014, Volume 132, Issue 4, pp. 428 - 436
Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Dependovirus - genetics | Genetic Therapy | Visual Fields - physiology | Prospective Studies | Intravitreal Injections | Humans | Middle Aged | Male | NADH Dehydrogenase - genetics | Optic Atrophy, Hereditary, Leber - genetics | Retinal Ganglion Cells - metabolism | Retinal Ganglion Cells - pathology | Young Adult | DNA, Mitochondrial - genetics | DNA Mutational Analysis | Endpoint Determination | Adult | Female | Optic Atrophy, Hereditary, Leber - diagnosis | Child | Visual Acuity - physiology | Electroretinography | Nerve Fibers - pathology | Tomography, Optical Coherence | Clinical Trials as Topic | Optic Atrophy, Hereditary, Leber - therapy | Adolescent | Visual Field Tests | Genetic Vectors | Clinical trials | Care and treatment | Usage | Optic atrophy | Gene therapy | Medical history taking | Index Medicus | Abridged Index Medicus
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A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy
Brain (London, England : 1878), ISSN 0006-8950, 9/2011, Volume 134, Issue 9, pp. 2677 - 2686
mitochondrial encephalomyopathy | optic atrophy | mitochondrial DNA | LHON | optic neuropathy | mitochondrial disease | idebenone | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction | Neurology | Biological and medical sciences | Medical sciences | Nervous system (semeiology, syndromes) | Prospective Studies | Double-Blind Method | Humans | Middle Aged | Ubiquinone - analogs & derivatives | Male | Antioxidants - pharmacology | Ubiquinone - pharmacology | Young Adult | Optic Atrophy, Hereditary, Leber - drug therapy | Antioxidants - therapeutic use | Visual Acuity - drug effects | DNA, Mitochondrial - genetics | Retina - ultrastructure | Adolescent | Contrast Sensitivity - drug effects | Placebos | Ubiquinone - therapeutic use | Adult | Female | Aged | Mutation | Optic Atrophy, Hereditary, Leber - physiopathology | Index Medicus | Abridged Index Medicus | Original
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