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herv-k (185) 185
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gene expression regulation, viral (23) 23
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1. Full Text Diversity of DNA and RNA Viruses in Indoor Air As Assessed via Metagenomic Sequencing
by Rosario, Karyna and Fierer, Noah and Miller, Shelly and Luongo, Julia and Breitbart, Mya
Environmental Science & Technology, ISSN 0013-936X, 02/2018, Volume 52, Issue 3, pp. 1014 - 1027
Diverse bacterial and fungal communities inhabit human-occupied buildings and circulate in indoor air; however, viral diversity in these man-made environments... 
UNITED-STATES | HUMAN-PAPILLOMAVIRUS TYPES | ENVIRONMENTAL SCIENCES | HUMAN MICROBIOME | HUMAN SKIN | ENGINEERING, ENVIRONMENTAL | HOUSE-DUST | CERVICAL-CANCER | K HERV-K | HEALTHY SKIN | OUTDOOR AIR | MERKEL CELL POLYOMAVIRUS
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2. Full Text Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells
by Fuchs, Nina V and Loewer, Sabine and Daley, George Q and Izsvák, Zsuzsanna and Löwer, Johannes and Löwer, Roswitha
Retrovirology, ISSN 1742-4690, 10/2013, Volume 10, Issue 1, pp. 115 - 115
Background: Malignant human embryonal carcinoma cells (ECCs) rely on similar transcriptional networks as non-malignant embryonic stem cells (ESCs) to control... 
Human embryonic stem cells | Activation of human endogenous retrovirus K proviruses | Induced pluripotent stem cells | Embryoid body differentiation | Pluripotency marker | ANTIBODIES | ANDROGEN RECEPTOR | SOMATIC-CELLS | HUMAN TISSUES | HERV-K(HML-2) LOCI | IDENTIFICATION | TUMORS | REC | MELANOMA | VIROLOGY | ZINC-FINGER PROTEIN | Proteins | Stem cell research | Zinc finger proteins | RNA | Embryonic stem cells | Benign
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3. Full Text Utility of next‐generation RNA‐sequencing in identifying chimeric transcription involving human endogenous retroviruses
by Sokol, Martin and Jessen, Karen Margrethe and Pedersen, Finn Skou
APMIS, ISSN 0903-4641, 01/2016, Volume 124, Issue 1-2, pp. 127 - 139
Several studies have shown that human endogenous retroviruses and endogenous retrovirus‐like repeats (here collectively HERVs) impose direct regulation on... 
CSF1R | Chimeric transcription | CADM2 | SEMA3A | tumor suppressor regulation | Unannotated transcription | LTR2‐FABP7 | LTR12 ERV9 LTR repeat | Human endogenous retrovirus and endogenous retrovirus‐like repeats (HERVs) | chromatin immunoprecipitation with sequencing (ChIP‐seq) | Integration mapping | PRODH | TP63 | Paired‐end RNA‐sequencing (RNA‐seq) | Tumor suppressor regulation | Human endogenous retrovirus and endogenous retrovirus-like repeats (HERVs) | LTR2-FABP7 | Chromatin immunoprecipitation with sequencing (ChIP-seq) | Paired-end RNA-sequencing (RNA-seq) | INTEGRATION SITES | chromatin immunoprecipitation with sequencing (ChIP-seq) | MICROBIOLOGY | IMMUNOLOGY | PATHOLOGY | LONG TERMINAL REPEAT | PROSTATE-CANCER | GENE-EXPRESSION | H LTR ELEMENT | READ ALIGNMENT | TRANSPOSABLE ELEMENTS | HERV-K | INSERTIONAL MUTAGENESIS | BURROWS-WHEELER TRANSFORM | Promoter Regions, Genetic | Cell Adhesion Molecules - genetics | Humans | Gene Expression Regulation | Male | Endogenous Retroviruses - genetics | Transcription Factors - genetics | Terminal Repeat Sequences - genetics | RNA - genetics | Sequence Analysis, RNA - methods | Chromatin Immunoprecipitation | Tumor Suppressor Proteins - genetics | High-Throughput Nucleotide Sequencing | Sequence Analysis, RNA - standards | Genome, Human | Protein Isoforms - genetics | Semaphorin-3A - genetics | Retroviruses | Genetic transcription | RNA | Analysis | Genomics | Genes | Genomes
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4. Full Text A new Real-Time-RT-PCR for quantitation of human endogenous retroviruses type K (HERV-K) RNA load in plasma samples: Increased HERV-K RNA titers in HIV-1 patients with HAART non-suppressive regimens
by Contreras-Galindo, Rafael and González, Marta and Almodovar-Camacho, Sharilyn and González-Ramírez, Sandra and Lorenzo, Eric and Yamamura, Yasuhiro
Journal of Virological Methods, ISSN 0166-0934, 2006, Volume 136, Issue 1, pp. 51 - 57
Viral components of the human endogenous retroviruses type K (HERV-K) have been largely detected in plasma from HIV-1 infected individuals. A Sybr Green... 
HERV-K | HIV-1 | Real-Time RT-PCR | Sybr Green | HERV-K viral load | VIRAL LOAD | VIRUS-INFECTED PATIENTS | SEQUENCES | REVERSE-TRANSCRIPTASE | BIOCHEMICAL RESEARCH METHODS | ANTIRETROVIRAL THERAPY | DISCORDANT INCREASES | RESPONSES | RATES | VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EXPRESSION | T-CELLS | Reproducibility of Results | Endogenous Retroviruses - isolation & purification | Organic Chemicals | HIV Infections - virology | Humans | Fluorescence | Molecular Sequence Data | RNA, Viral - blood | Endogenous Retroviruses - genetics | Viral Load | Antiretroviral Therapy, Highly Active | Analysis of Variance | Base Sequence | Reverse Transcriptase Polymerase Chain Reaction - methods | Sensitivity and Specificity | Staining and Labeling | Cloning, Molecular | HIV Infections - complications | HIV Infections - drug therapy | Antiviral agents | Highly active antiretroviral therapy | HIV patients | RNA | HIV (Viruses) | Anti-HIV agents
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5. Full Text A contaminant-free assessment of Endogenous Retroviral RNA in human plasma
by Karamitros, Timokratis and Paraskevis, Dimitrios and Hatzakis, Angelos and Psichogiou, Mina and Elefsiniotis, Ioannis and Hurst, Tara and Geretti, Anna-Maria and Beloukas, Apostolos and Frater, John and Klenerman, Paul and Katzourakis, Aris and Magiorkinis, Gkikas
Scientific Reports, ISSN 2045-2322, 09/2016, Volume 6, Issue 1, p. 33598
Endogenous retroviruses (ERVs) comprise 6-8% of the human genome. HERVs are silenced in most normal tissues, up-regulated in stem cells and in placenta but... 
HERV-K | ELEMENTS | IN-VITRO | HUMAN-BREAST-CANCER | MULTIDISCIPLINARY SCIENCES | HIV-1 INFECTION | CELL-LINES | IDENTIFICATION | EXPRESSION | GENOME | HUMAN-POPULATIONS | Polymerase chain reaction | Cell culture | Placenta | Laboratories | Contaminants | Stem cells | Genomes | Ribonucleic acid--RNA | Contamination | Cancer
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6. Full Text Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
by Chiappinelli, Katherine B and Strissel, Pamela L and Desrichard, Alexis and Li, Huili and Henke, Christine and Akman, Benjamin and Hein, Alexander and Rote, Neal S and Cope, Leslie M and Snyder, Alexandra and Makarov, Vladimir and Buhu, Sadna and Slamon, Dennis J and Wolchok, Jedd D and Pardoll, Drew M and Beckmann, Matthias W and Zahnow, Cynthia A and Merghoub, Taha and Chan, Timothy A and Baylin, Stephen B and Strick, Reiner
Cell, ISSN 0092-8674, 08/2015, Volume 162, Issue 5, pp. 974 - 986
We show that DNA methyltransferase inhibitors (DNMTis) upregulate immune signaling in cancer through the viral defense pathway. In ovarian cancer (OC), DNMTis... 
CELL LUNG-CANCER | HERV-K | NONCODING RNA | HUMAN GENOME | PD-1 BLOCKADE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-CELLS | CPG METHYLATION | OVARIAN-CANCER | HUMAN BREAST-CANCER | CODING ENVELOPE GENES | CELL BIOLOGY | Lung Neoplasms - drug therapy | DNA Modification Methylases - antagonists & inhibitors | Humans | Mice, Inbred C57BL | Endogenous Retroviruses - genetics | Interferon Type I - immunology | Azacitidine - pharmacology | Lung Neoplasms - immunology | Animals | Melanoma - immunology | Immunotherapy | Cell Line, Tumor | Ovarian Neoplasms - therapy | Female | Mice | RNA, Double-Stranded - metabolism | Melanoma - therapy | DNA Methylation - drug effects | Ovarian Neoplasms - immunology | RNA | Transferases | Genomics | Melanoma | Genomes | Biological response modifiers | Gene expression | Ovarian cancer | DNA | Interferon beta | Genetic aspects | Sensors | Methylation | Cancer | Genes
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7. Full Text Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences
by Cho, Yoon-Jae and Pomeroy, Scott L and Skog, Johan and Lessard, Ryan and Balaj, Leonora and Dai, Lixin and Breakefield, Xandra O
Nature Communications, ISSN 2041-1723, 02/2011, Volume 2, Issue 1, pp. 180 - 180
Tumour cells release an abundance of microvesicles containing a selected set of proteins and RNAs. Here, we show that tumour microvesicles also carry DNA,... 
BREAST-CANCER | HORIZONTAL TRANSFER | HERV-K | DOUBLE MINUTES | MESSENGER-RNA | GENE | MULTIDISCIPLINARY SCIENCES | REVERSE-TRANSCRIPTASE | ENDOTHELIAL-CELLS | APOPTOTIC BODIES | DIAGNOSTIC BIOMARKERS | Neoplasms - metabolism | Endothelial Cells - metabolism | Humans | DNA, Complementary - genetics | Secretory Vesicles - metabolism | RNA Precursors - genetics | Gene Dosage | Reverse Transcriptase Polymerase Chain Reaction | Proto-Oncogene Proteins c-myc - metabolism | Retroelements - genetics | Animals | Electrophoresis, Agar Gel | Cell Line, Tumor | Polymorphism, Single Nucleotide - genetics | RNA Precursors - metabolism | Mice | Umbilical Veins - cytology
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8. Full Text Down-regulation of human endogenous retrovirus type K (HERV-K) viral env RNA in pancreatic cancer cells decreases cell proliferation and tumor growth
by Li, Ming and Radvanyi, Laszlo and Yin, Bingnan and Li, Jia and Chivukula, Raghavender and Lin, Kevin and Lu, Yue and Shen, JianJun and Chang, David Z and Li, Donghui and Johanning, Gary L and Wang-Johanning, Feng
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 10/2017, Volume 23, Issue 19, pp. 5892 - 5911
HERV-K | pancreatic cancer | RAS-ERK-RSK pathway | shRNA
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9. Full Text Mouse Mammary Tumor Virus Encodes a Self-Regulatory RNA Export Protein and Is a Complex Retrovirus
by Jennifer A. Mertz and Melissa S. Simper and Mary M. Lozano and Shelley M. Payne and Jaquelin P. Dudley
Journal of Virology, ISSN 0022-538X, 12/2005, Volume 79, Issue 23, pp. 14737 - 14747
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
VIRAL MESSENGER-RNA | HTDV/HERV-K | VIROLOGY | LONG TERMINAL REPEAT | REV TRANS-ACTIVATOR | NEGATIVE REGULATION | B LEUKEMOGENIC VIRUS | GENE-EXPRESSION | SIGNAL RECOGNITION PARTICLE | NUCLEAR EXPORT | BINDING | Animals | RNA, Viral - genetics | Viral Proteins - genetics | Mammary Tumor Virus, Mouse - metabolism | Mice | RNA, Viral - metabolism | Mammary Tumor Virus, Mouse - genetics | Viral Proteins - metabolism | Genome and Regulation of Viral Gene Expression
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10. Full Text Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis
by Garson, Jeremy A and Usher, Louise and Al-Chalabi, Ammar and Huggett, Jim and Day, Edmund F and McCormick, Adele L
Acta neuropathologica communications, ISSN 2051-5960, 03/2019, Volume 7, Issue 1, pp. 45 - 9
Over the past two decades a number of studies have demonstrated activity of the retroviral enzyme reverse transcriptase in the serum of patients with sporadic... 
HERV-K | Human endogenous retrovirus | HERV-W | RNA | ALS | Amyotrophic lateral sclerosis | Premotor cortex | REVERSE-TRANSCRIPTASE | RISK | SERUM | NEUROSCIENCES | GENES | NORMALIZATION | PCR | Highly active antiretroviral therapy | Enzymes | Medical research | Analysis | Medicine, Experimental | DNA polymerases | Genetic engineering | Motor neurone disease | Infections | Genomes | Family medical history | Gene expression | Studies | Proteins | Neurology | Brain research | Human immunodeficiency virus--HIV | Drug therapy | Methods | Quantitative analysis
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11. Full Text Detection of HERV-K(HML-2) viral RNA in plasma of HIV type 1-infected individuals
by Contreras-Galindo, Rafael and Kaplan, Mark H and Markovitz, David M and Lorenzo, Eric and Yamamura, Yasuhiro
AIDS Research and Human Retroviruses, ISSN 0889-2229, 10/2006, Volume 22, Issue 10, pp. 979 - 984
Approximately 8% of the human genome sequence is composed by human endogenous retroviruses ( HERVs), most of which are defective. HERV-K(HML-2) is the youngest... 
ANTIBODIES | HUMAN TISSUES | INFECTIOUS DISEASES | PROTEIN | SEQUENCES | REVERSE-TRANSCRIPTASE | QUANTITATION | IMMUNOLOGY | HUMAN ENDOGENOUS RETROVIRUS | HERV-K | VIROLOGY | INSERTIONAL POLYMORPHISMS | EXPRESSION | HIV Infections - blood | HIV-1 | HIV Infections - virology | Hepatitis C - blood | Humans | Hepatitis C - virology | Molecular Sequence Data | RNA, Viral - blood | Endogenous Retroviruses - genetics | Reverse Transcriptase Polymerase Chain Reaction
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12. Full Text Human endogenous retrovirus type K antibodies and mRNA as serum biomarkers of early‐stage breast cancer
by Wang‐Johanning, Feng and Li, Ming and Esteva, Francisco J and Hess, Kenneth R and Yin, Bingnan and Rycaj, Kiera and Plummer, Joshua B and Garza, Jeremy G and Ambs, Stefan and Johanning, Gary L
International Journal of Cancer, ISSN 0020-7136, 02/2014, Volume 134, Issue 3, pp. 587 - 595
A simple and accurate test to detect early‐stage breast cancer has not been developed. Previous studies indicate that the level of human endogenous retrovirus... 
breast cancer | early detection | endogenous retroviruses | metastasis | biomarkers | HERV‐K | HERV-K | AUTOANTIBODIES | QUANTITATION | RISK | IDENTIFICATION | CARCINOMA IN-SITU | THERAPY | GENE | ONCOLOGY | ENVELOPE TRANSCRIPTS | EXPRESSION | Carcinoma, Intraductal, Noninfiltrating - blood | Enzyme-Linked Immunosorbent Assay | Humans | RNA, Viral - blood | Antibodies, Viral - blood | Biomarkers, Tumor - blood | Breast Neoplasms - virology | Neoplasm Metastasis | Carcinoma, Intraductal, Noninfiltrating - pathology | RNA, Messenger - blood | Breast Neoplasms - pathology | Carcinoma, Intraductal, Noninfiltrating - virology | Breast Neoplasms - blood | Endogenous Retroviruses - immunology | Female | Real-Time Polymerase Chain Reaction | Proteins | Viral antibodies | Messenger RNA | Antibodies | Development and progression | Breast cancer | Biological markers | Confidence intervals | Immunoglobulins | Womens health | Biomarkers | Mammography | Ribonucleic acid--RNA
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13. Full Text Response to the Letter from Garcia-Montojo and colleagues concerning our paper entitled, Quantitative analysis of human endogenous retrovirus-K transcripts in postmortem premotor cortex fails to confirm elevated expression of HERV-K RNA in amyotrophic lateral sclerosis
by Garson, JA and Usher, L and Al-Chalabi, A and Huggett, J and Day, EF and McCormick, AL
ACTA NEUROPATHOLOGICA COMMUNICATIONS, ISSN 2051-5960, 07/2019, Volume 7, Issue 1, pp. 102 - 4
Briefly, these are, i) concerns regarding our selection of controls, in particular the number of control subjects with cancer, ii) concerns regarding the... 
HERV-K | Human endogenous retroviruses | QUALITY | RNA | REFERENCE GENES | Amyotrophic lateral sclerosis | RT-qPCR | NEUROSCIENCES | Brain | Genomics | Quality | Metastasis | Gene expression | Kinases | Alzheimers disease | Patients | Cancer | Quantitative analysis
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14. Full Text Human Endogenous Retrovirus Family HERV-K(HML-2) RNA Transcripts Are Selectively Packaged into Retroviral Particles Produced by the Human Germ Cell Tumor Line Tera-1 and Originate Mainly from a Provirus on Chromosome 22q11.21
by Klemens Ruprecht and Humberto Ferreira and Aline Flockerzi and Silke Wahl and Marlies Sauter and Jens Mayer and Nikolaus Mueller-Lantzsch
Journal of Virology, ISSN 0022-538X, 10/2008, Volume 82, Issue 20, pp. 10008 - 10016
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
HERV-K | HUMAN GENOME | PROTEIN | VIROLOGY | MULTIPLE-SCLEROSIS | SEQUENCES | MOLECULAR-CLONING | INSERTIONAL POLYMORPHISMS | IDENTIFICATION | EXPRESSION | VIRUSES | Humans | Virion - genetics | Endogenous Retroviruses - genetics | Chromosomes, Human, Pair 22 - virology | Virion - metabolism | Virus Assembly | Virus Integration | Proviruses - metabolism | Chromosomes, Human, Pair 22 - genetics | Endogenous Retroviruses - metabolism | Proviruses - genetics | Cell Line, Tumor | RNA, Viral - metabolism | Genome and Regulation of Viral Gene Expression
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