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Microbial Biotechnology, ISSN 1751-7915, 05/2016, Volume 9, Issue 3, pp. 355 - 368
...) in the yeast Pichia pastoris; this membrane protein is responsible for the synthesis of rabies neutralizing antibodies... 
HETEROLOGOUS PROTEIN EXPRESSION | YEAST | SYSTEM | SECRETORY EXPRESSION | OVEREXPRESSION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENE DOSAGE | PHYSIOLOGICAL-RESPONSE | MICROBIOLOGY | ENDOPLASMIC-RETICULUM | STRESS | INSULIN PRECURSOR | Metabolic Engineering | Glycoproteins - metabolism | Antigens, Viral - genetics | Neutralization Tests | Recombinant Proteins - biosynthesis | Antibodies, Neutralizing - immunology | Pichia - metabolism | Codon | Viral Envelope Proteins - metabolism | Antigens, Viral - biosynthesis | Glycoproteins - genetics | Recombinant Proteins - metabolism | Gene Expression | Viral Envelope Proteins - genetics | Viral Envelope Proteins - biosynthesis | Gene Dosage | Recombinant Proteins - genetics | Unfolded Protein Response | Protein Folding | Glycoproteins - biosynthesis | Antigens, Viral - immunology | Glycoproteins - immunology | Recombinant Proteins - immunology | Pichia - genetics | Viral Envelope Proteins - immunology | Pichia - growth & development | Yeasts | Baking yeast | Yeast | Copy number | Secretion | Antibodies | Viruses | Glycoproteins | Gene expression | Optimization | Membrane proteins | Proteins | Protein folding | Rabies | Neutralizing | Protein expression | Acid phosphatase | Folding | Recombinant | Viral Envelope Proteins/genetics | Viral Envelope Proteins/immunology | Glycoproteins/immunology | Antigens, Viral/biosynthesis | Recombinant Proteins/immunology | Pichia/growth & development | Antigens, Viral/genetics | Recombinant Proteins/metabolism | Life Sciences | Viral Envelope Proteins/metabolism | Viral Envelope Proteins/biosynthesis | Glycoproteins/biosynthesis | Antibodies, Neutralizing/immunology | Antigens, Viral/immunology | Glycoproteins/metabolism | Recombinant Proteins/biosynthesis | Recombinant Proteins/genetics | Pichia/genetics | Glycoproteins/genetics | Pichia/metabolism
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 04/2011, Volume 103, Issue 8, pp. 645 - 661
.... MET mRNA, and protein expression and signal transduction were compared in treated and untreated cells, and the involvement of the DNA-damage sensor ataxia telangiectasia mutated (ATM... 
STEM-CELLS | IN-VITRO | ONCOLOGY | TYROSINE KINASE | HGF | CELL INVASION | RECEPTOR | EPITHELIAL-MESENCHYMAL TRANSITIONS | NF-KAPPA-B | SCATTER-FACTOR | PROTOONCOGENE | Humans | Neoplasm Invasiveness - prevention & control | Radiation Tolerance | Receptors, Growth Factor - antagonists & inhibitors | NF-kappa B - metabolism | RNA, Messenger - metabolism | NF-kappa B - radiation effects | Receptors, Growth Factor - genetics | Proto-Oncogene Proteins c-met - radiation effects | Signal Transduction - radiation effects | Protein-Serine-Threonine Kinases - metabolism | Radiation, Ionizing | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - radiation effects | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Cell Cycle Proteins - metabolism | Cell Cycle Proteins - radiation effects | Receptors, Growth Factor - radiation effects | Proto-Oncogene Proteins c-met - drug effects | Ataxia Telangiectasia Mutated Proteins | Phosphorylation - radiation effects | Cell Line, Tumor | Mice | RNA, Small Interfering | Tumor Suppressor Proteins - radiation effects | Receptors, Growth Factor - metabolism | Neoplasms - metabolism | Proto-Oncogene Proteins c-met - metabolism | Apoptosis - radiation effects | Up-Regulation - radiation effects | Transcription, Genetic - radiation effects | Transplantation, Heterologous | Sulfones - pharmacology | DNA-Binding Proteins - metabolism | Chromatin Immunoprecipitation | Protein-Serine-Threonine Kinases - radiation effects | Tumor Suppressor Proteins - genetics | Polymerase Chain Reaction | Cell Cycle Proteins - genetics | Indoles - pharmacology | Neoplasms - radiotherapy | Gene Expression Regulation, Neoplastic - drug effects | In Situ Nick-End Labeling | Enzyme-Linked Immunosorbent Assay | Radiation-Sensitizing Agents - pharmacology | Gene Silencing | Protein-Serine-Threonine Kinases - genetics | DNA-Binding Proteins - genetics | Cell Survival - radiation effects | Cell Movement - radiation effects | Proto-Oncogene Proteins c-met - genetics | Blotting, Northern | Animals | NF-kappa B - genetics | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Receptors, Growth Factor - drug effects | DNA Damage - radiation effects | Mitogen-Activated Protein Kinases - metabolism | Ionizing radiation | Physiological aspects | Genetic aspects | Cancer invasiveness | Research | Gene expression | Radiotherapy | Health aspects
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 2011, Volume 1808, Issue 8, pp. 2059 - 2066
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 33, pp. 13745 - 13757
Messenger RNA alternative splicing (AS) regulates the expression of a variety of genes involved in both physiological and pathological processes. AS of the... 
TARGET | PREDICTS | MESSENGER-RNA | VARIANTS | SPECIFICITY | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | SURVIVIN-DELTA-EX3 | CELL | EXPRESSION | RNA-Binding Proteins - genetics | Alternative Splicing | Exons | Inhibitor of Apoptosis Proteins - genetics | Humans | Neoplasm Proteins - antagonists & inhibitors | Transplantation, Heterologous | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | RNA, Neoplasm - metabolism | DNA-Binding Proteins - metabolism | Protein Isoforms - metabolism | RNA Interference | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Gene Deletion | Clone Cells | Inhibitor of Apoptosis Proteins - metabolism | Neoplasm Proteins - genetics | RNA-Binding Proteins - antagonists & inhibitors | RNA, Neoplasm - chemistry | Recombinant Proteins - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Mutagenesis, Site-Directed | Response Elements | Recombinant Proteins - chemistry | Zebrafish | Tumor Burden | DNA-Binding Proteins - genetics | Point Mutation | Animals | Adaptor Proteins, Signal Transducing - genetics | CRISPR-Cas Systems | Embryo, Nonmammalian | RNA, Messenger - chemistry | Neoplasm Transplantation - pathology | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Protein Isoforms - antagonists & inhibitors | RNA-Binding Proteins - metabolism | Protein Isoforms - genetics | survivin | KHDRBS1 | alternative splicing | survivin DEx3 | gene regulation | cancer | cancer biology | Sam68 | Cell Biology
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, pp. e0152626 - e0152626
.... The co-expression of recombinant proteins with molecular chaperones has been proposed as one way to improve the production of the former in E. coli. E... 
SUPPRESS | IN-VITRO | SUBSTRATE-BINDING | DNAK | GENE | MECHANISM | TRIGGER FACTOR | MOLECULAR CHAPERONES | MULTIDISCIPLINARY SCIENCES | ORNITHINE-DECARBOXYLASE | HETEROLOGOUS EXPRESSION | HSP40 Heat-Shock Proteins - metabolism | Molecular Chaperones - metabolism | HSP40 Heat-Shock Proteins - genetics | Adenosylmethionine Decarboxylase - metabolism | Bacterial Proteins - genetics | Molecular Chaperones - genetics | Escherichia coli Proteins - metabolism | HSP70 Heat-Shock Proteins - genetics | Adenosylmethionine Decarboxylase - genetics | Recombinant Proteins - biosynthesis | HSP70 Heat-Shock Proteins - metabolism | Recombinant Proteins - isolation & purification | Plasmodium falciparum - genetics | Escherichia coli - metabolism | Escherichia coli Proteins - genetics | Protein Binding | Bacterial Proteins - metabolism | Usage | Gene mutations | Analysis | Escherichia coli | Heat shock proteins | Genetic aspects | Research | Gene expression | Recombinant proteins | S-adenosylmethionine | Adenosylmethionine | Erythrocytes | Biochemistry | Chaperones | Parasites | Hydrophobicity | Polyamines | Proteins | Adenosylmethionine decarboxylase | E coli | Protein folding | Proteolysis | Quality | Cooperation | DnaK protein | Constitution | Recombinant | Binding | Malaria | Hsp70 protein | RNA polymerase | S-Adenosylmethionine | Substrates | Heat | Mutagenesis | Antimalarial agents | Site-directed mutagenesis | Adenosine triphosphatase | Heat shock | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, p. e99404
.... BM-1197 binds to Bcl-2 and Bcl-xL proteins with K-i values less than 1 nM and shows >1,000-fold selectivity over Mcl-1... 
BCL-X-L | APOPTOSIS | POTENT | SMALL-MOLECULE INHIBITORS | MCL-1 | MULTIDISCIPLINARY SCIENCES | CHRONIC LYMPHOCYTIC-LEUKEMIA | BH3 MIMETIC ABT-737 | PROTEINS | ABT-263 | FAMILY | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Humans | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Transplantation, Heterologous | Antineoplastic Agents - therapeutic use | Proto-Oncogene Proteins c-bcl-2 - metabolism | Bcl-2-Like Protein 11 | RNA Interference | bcl-X Protein - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Cell Line | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Tumor Suppressor Proteins - metabolism | Aniline Compounds - pharmacology | Sulfonamides - chemistry | Cytochromes c - metabolism | bcl-2-Associated X Protein - metabolism | Antineoplastic Agents - chemistry | Mice, SCID | Sulfonamides - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Apoptosis Regulatory Proteins - metabolism | Animals | Sulfonamides - therapeutic use | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Mice | Aniline Compounds - chemistry | Aniline Compounds - therapeutic use | bcl-X Protein - metabolism | RNA, Small Interfering - metabolism | Prevention | Proteins | Cancer | Tumors | Apoptosis | Cytochrome | Cell culture | Regulators | Animal models | Bax protein | Bcl-2 protein | Leukemia | Lung cancer | Values | Cancer therapies | Cytosol | Mitochondria | Bcl-x protein | Xenografts | Membrane potential | Small cell lung carcinoma | Internal medicine | Melanoma | Caspase | Pharmacology | Embryo fibroblasts | Tumor cell lines | Mcl-1 protein | Membrane proteins | Cytochrome c | Medicine | Inhibitors | Cell death | Lymphomas | Laboratory animals
Journal Article
Cancer Research, ISSN 0008-5472, 06/2006, Volume 66, Issue 12, pp. 6063 - 6071
Journal Article
FEMS Microbiology Reviews, ISSN 0168-6445, 2000, Volume 24, Issue 1, pp. 45 - 66
Journal Article
Molecular and Cellular Proteomics, ISSN 1535-9476, 12/2013, Volume 12, Issue 12, pp. 3976 - 3986
.... Progress in the functional and molecular characterization of P. falciparum merozoite proteins, however, has been hampered... 
HIGH-LEVEL | ENHANCED EXPRESSION | RTS,S/AS01 MALARIA VACCINE | ESCHERICHIA-COLI | BIOCHEMICAL RESEARCH METHODS | PARASITE PLASMODIUM-FALCIPARUM | MULTIGENE FAMILY | PHASE-3 TRIAL | INHIBITORY ANTIBODIES | HETEROLOGOUS EXPRESSION | ERYTHROCYTE INVASION | Proteome - genetics | Antigens, Protozoan - immunology | Immune Sera - chemistry | Humans | Merozoite Surface Protein 1 - genetics | Peptide Library | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Merozoite Surface Protein 1 - metabolism | Antigens, Protozoan - metabolism | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Proteome - immunology | Cloning, Molecular | HEK293 Cells | Antigens, Surface - metabolism | Plasmodium falciparum - metabolism | Antigens, Protozoan - genetics | Membrane Proteins - metabolism | Carrier Proteins - immunology | Merozoites - metabolism | Merozoites - immunology | Recombinant Proteins - metabolism | Gene Expression | Membrane Proteins - genetics | Molecular Sequence Annotation | Antigens, Surface - genetics | Sialic Acids - metabolism | Membrane Proteins - immunology | Recombinant Proteins - genetics | Carrier Proteins - genetics | Carrier Proteins - metabolism | Recombinant Proteins - immunology | Merozoite Surface Protein 1 - immunology | Protein Binding | Erythrocytes - parasitology | Merozoites - chemistry | Antigens, Surface - immunology | Proteome - metabolism | Protozoan Proteins - immunology | Technological Innovation and Resources
Journal Article