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hexim1 (105) 105
index medicus (96) 96
humans (77) 77
p-tefb (72) 72
biochemistry & molecular biology (55) 55
positive transcriptional elongation factor b - metabolism (45) 45
rna-binding proteins - metabolism (41) 41
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7sk snrna (29) 29
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rna polymerase ii - metabolism (21) 21
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7sk snrnp (20) 20
mice (19) 19
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positive transcriptional elongation factor b - genetics (16) 16
complexes (15) 15
hiv-1 - genetics (15) 15
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ribonucleoproteins, small nuclear - metabolism (15) 15
transcription factors - metabolism (15) 15
cyclin t1 (14) 14
gene expression (14) 14
bromodomain protein brd4 (13) 13
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molecular biology (13) 13
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tat (13) 13
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rna, small nuclear - metabolism (12) 12
tat gene products, human immunodeficiency virus - metabolism (12) 12
7sk rna (11) 11
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positive transcriptional elongation factor b - antagonists & inhibitors (8) 8
ribonucleoproteins - metabolism (8) 8
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Circulation Research, ISSN 0009-7330, 06/2009, Volume 104, Issue 12, pp. 1327 - 1329
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2012, Volume 287, Issue 43, pp. 36609 - 36616
Journal Article
Journal Article
Circulation research, ISSN 0009-7330, 2/2008, Volume 102, Issue 4, pp. 415 - 422
Our previous studies and those of others indicated that the transcription factor Hexamethylene-bis-acetamide-inducible protein 1 (HEXIM1) is a tumor suppressor... 
HEXIM1 | development | vascular | heart
Journal Article
by Ho, PL and Ong, HK and Teo, J and Ow, DSW and Chao, SH
FRONTIERS IN MICROBIOLOGY, ISSN 1664-302X, 02/2019, Volume 10, pp. 203 - 203
The emergence of antibiotic resistant bacteria is one of the biggest threats to human health worldwide. In 2017, World Health Organization listed the world's... 
HEXIM1 | ANTIBACTERIAL PEPTIDES | COMPLEX | MECHANISM | MEMBRANE | MICROBIOLOGY | POLYMERASE-II TRANSCRIPTION | PROTEIN-SYNTHESIS | P-TEFB | BLOCKS | translation | carbapenem-resistant | INHIBITS TRANSLATION | antibiotic resistant bacteria | antimicrobial peptide | 7SK RNA
Journal Article
Circulation research, ISSN 0009-7330, 6/2009, Volume 104, Issue 12, pp. 1327 - 1329
Journal Article
Journal Article
mBio, ISSN 2150-7511, 02/2019, Volume 10, Issue 1, p. e02662-18
The intrinsically disordered HIV-1 Tat protein binds the viral RNA transactivation response structure (TAR), which recruits transcriptional cofactors,... 
HIV-1 Tat | dCA | molecular docking | structure-activity relationship | structure-based design | HEXIM1 | COMPLEX | COACTIVATOR | PROTEIN | TRANSCRIPTION | POSITIVE REGULATOR | MICROBIOLOGY | B P-TEFB | REPLICATION | ELONGATION | TRANSACTIVATION | Index Medicus
Journal Article
RNA, ISSN 1355-8382, 01/2019, Volume 25, Issue 1, pp. 135 - 146
Deciphering the conformations of RNAs in their cellular environment allows identification of RNA elements with potentially functional roles within biological... 
Chemical probing | RNA structure | Carbodiimide | In-cell | HEXIM1 | in-cell | RIBONUCLEOPROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | RIBOSOMAL-SUBUNITS | CONFORMATION | 7SK | NONCODING RNA | PROTEIN INTERACTIONS | chemical probing | carbodiimide | SECONDARY STRUCTURE | DOMAINS | REVEALS | RNA probes | DNA probes | Adenine | Cytosine | Nucleotides | Ribonucleic acid--RNA | Uracil | Guanine | Acylation | Conformation | Dimethyl sulfate | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 387 - 399.e5
The DNA-mediated innate immune response underpins anti-microbial defenses and certain autoimmune diseases. Here we used immunoprecipitation, mass spectrometry,... 
HEXIM1 | DNA-PK | innate immune response | herpesvirus | paraspeckles | cGAS | NEAT1 | interferon stimulatory DNA | DEFENSE | PROTEIN | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | SENSOR | POLYMERASE-II | 7SK RNA | BINDING | GMP-AMP SYNTHASE | P-TEFB | CELL BIOLOGY | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Octamer Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Herpesvirus 8, Human - immunology | RNA, Long Noncoding - immunology | PTB-Associated Splicing Factor - genetics | RNA Interference | Calcium-Binding Proteins - immunology | Octamer Transcription Factors - genetics | Nucleotidyltransferases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Signal Transduction | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | PTB-Associated Splicing Factor - metabolism | Nuclear Matrix-Associated Proteins - metabolism | PTB-Associated Splicing Factor - immunology | DNA - metabolism | Host-Pathogen Interactions | Nuclear Matrix-Associated Proteins - genetics | HeLa Cells | RNA-Binding Proteins - metabolism | Calcium-Binding Proteins - genetics | RNA-Binding Proteins - genetics | Multiprotein Complexes | Human Umbilical Vein Endothelial Cells - immunology | Intracellular Signaling Peptides and Proteins - immunology | Human Umbilical Vein Endothelial Cells - virology | Interferon Regulatory Factor-3 - genetics | Ku Autoantigen - genetics | Transfection | HEK293 Cells | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Octamer Transcription Factors - metabolism | Interferon Regulatory Factor-3 - immunology | Calcium-Binding Proteins - metabolism | DNA - immunology | Nuclear Matrix-Associated Proteins - immunology | Ku Autoantigen - immunology | Membrane Proteins - immunology | Nuclear Proteins - metabolism | Ku Autoantigen - metabolism | RNA, Long Noncoding - genetics | Immunity, Innate | Nuclear Proteins - immunology | DNA - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein Binding | Nucleotidyltransferases - immunology | RNA, Long Noncoding - metabolism | RNA sequencing | Immune response | RNA | DNA | Genetic research | Interferon | Biological response modifiers | Mass spectrometry | Index Medicus | Human Umbilical Vein Endothelial Cells | Nuclear Matrix-Associated Proteins | Herpesvirus 8, Human | RNA-Binding Proteins | Life Sciences | Interferon Regulatory Factor-3 | Genetics | Calcium-Binding Proteins | Intracellular Signaling Peptides and Proteins | PTB-Associated Splicing Factor | Nuclear Proteins | Membrane Proteins | Nucleotidyltransferases | Ku Autoantigen | Octamer Transcription Factors | RNA, Long Noncoding
Journal Article
RNA, ISSN 1355-8382, 12/2016, Volume 22, Issue 12, pp. 1844 - 1858
The small nuclear 7SK RNA regulates RNA polymerase II (RNA Pol II) transcription, by sequestering and inhibiting the positive transcription elongation factor b... 
Hexim | NMR | RNA | TAR | TAT | 7SK | HEXIM1 | PROTEIN | Tat | POSITIVE TRANSCRIPTION | NMR-SPECTROSCOPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING DOMAIN | POLYMERASE-II TRANSCRIPTION | P-TEFB | TRIPLE-RESONANCE EXPERIMENT | IN-VIVO | DIPOLAR COUPLINGS | Nuclear Magnetic Resonance, Biomolecular | RNA, Small Nuclear - chemistry | Solutions | Nucleic Acid Conformation | Index Medicus
Journal Article