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BioFactors, ISSN 0951-6433, 05/2019, Volume 45, Issue 3, pp. 401 - 415
Tumor hypoxia is positively correlated with tumor aggressiveness and hence is a negative prognostic factor in cancer. As normal cells usually do not experience... 
hypoxia | HIF‐1α | cinnamaldehyde | metastasis | EMT | angiogenesis
Journal Article
Medicinal Research Reviews, ISSN 0198-6325, 07/2018, Volume 38, Issue 4, pp. 1404 - 1442
Tumor hypoxia is a common feature in most solid tumors and is associated with overexpression of the hypoxia response pathway. Overexpression of the... 
structure–activity relationship | tumor hypoxia | chemotype | angiogenesis | HIF‐1 inhibitors | HIF-1 inhibitors | Hypoxia | Cancer
Journal Article
Progress in Biophysics and Molecular Biology, ISSN 0079-6107, 08/2019
Journal Article
New Journal of Chemistry, ISSN 1144-0546, 2017, Volume 41, Issue 19, pp. 10550 - 10554
The luminescence properties of nido-carborane (7,8-dicarba-nido-carborate anion)-substituted tolane derivatives were investigated. It was shown that the... 
TRIPHENYLAMINE | AGGREGATION-INDUCED EMISSION | O-CARBORANE | (HIF)-1 TRANSCRIPTIONAL ACTIVITY | COMPLEXES | STATE | PHOTOPHYSICAL PROPERTIES | ELEMENT-BLOCKS | CHARGE-TRANSFER | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Cytoskeleton, ISSN 1949-3584, 01/2019, Volume 76, Issue 1, pp. 123 - 130
We have shown previously that septin 9 isoform 1 (SEPT9_i1) protein associates with hypoxia‐inducible factor (HIF)‐1α to augment HIF‐1 transcriptional activity... 
HIF‐1α | cancer | SEPT9_i1 | translocation | importin‐α7 | importin-α7 | HIF-1α | Hypoxia | Transcription | Prostate | Septin | Prostate cancer | Nuclear transport
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 08/2019, Volume 29, Issue 16, pp. 2327 - 2331
The novel marine pyrrole alkaloid neolamellarin A derived from sponge has been shown to inhibit hypoxia-induced HIF-1 activity. In this work, we designed and... 
Anti-tumor | Marine alkaloids | Hypoxia inducible factor (HIF)-1 | Neolamellarin A | Structure-activity relationship | Drugstores | Alkaloids | Fine chemicals | Analysis | Pharmacy | Luciferase | Index Medicus
Journal Article
Glia, ISSN 0894-1491, 11/2015, Volume 63, Issue 11, pp. 1933 - 1952
Microglia are central nervous system (CNS)‐resident immune cells, that play a crucial role in neuroinflammation. Hypoxia‐inducible factor‐1 (HIF‐1), the main... 
HIF‐1α | signaling pathways | inflammation | TNF‐α | VEGF | microglia cells | GLUT‐1 | iNOS
Journal Article
Cancer Science, ISSN 1347-9032, 05/2018, Volume 109, Issue 5, pp. 1627 - 1637
Substantial data from preclinical studies have revealed the biphasic effects of statins on cardiovascular angiogenesis. Although some have reported the... 
| simvastatin | AMPK | anti‐angiogenesis | HIF | statin | HIF-1α | anti-angiogenesis | Index Medicus | HIF‐1α | Original
Journal Article
International Journal of Cancer, ISSN 0020-7136, 06/2003, Volume 105, Issue 2, pp. 176 - 181
HIF‐1 is reported to transactivate expression of VEGF, which is an important angiogenic factor. To determine whether HIF‐1α plays a role in angiogenesis... 
HIF‐1α | colorectal cancer | vascular endothelial growth factor | angiogenesis | Angiogenesis | HIF-1α | Vascular endothelial growth factor | Colorectal cancer
Journal Article
Journal of Materials Chemistry C, ISSN 2050-7534, 2017, Volume 5, Issue 38, pp. 10047 - 10054
This manuscript describes the synthesis and optical properties of a series of anthracenyl-o-carborane dyads exhibiting highly-efficient luminescence with... 
BORON COMPLEXES | FLUORESCENCE PROPERTIES | PHYSICS, APPLIED | CONJUGATED POLYMERS | AGGREGATION-INDUCED EMISSION | IRIDIUM COMPLEXES | MATERIALS SCIENCE, MULTIDISCIPLINARY | (HIF)-1 TRANSCRIPTIONAL ACTIVITY | OPTICAL-PROPERTIES | PHOTOPHYSICAL PROPERTIES | CHARGE-TRANSFER | BODIPY DERIVATIVES
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2007, Volume 120, Issue 7, pp. 1451 - 1458
Hypoxia stabilizes HIF‐1α (Hypoxia Inducible Factor‐1α), which then triggers the expression of several genes involved in many aspects of cancer progression,... 
breast cancer | HIF‐1α | immunohistochemistry | prognosis | predictive factor | CA IX | Immunohistochemistry | Breast cancer | HIF-1α | Prognosis | Predictive factor | CARBONIC-ANHYDRASE-IX | HIF-1 alpha | PROTEIN | MARKER | CA 1X | CANCER | FACTOR 1-ALPHA HIF-1-ALPHA | OVEREXPRESSION | ONCOLOGY | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | HIF-ALPHA | EXPRESSION | UBIQUITIN-PROTEASOME PATHWAY
Journal Article
BioFactors, ISSN 0951-6433, 05/2019, Volume 45, Issue 3, pp. 364 - 373
Prostate cancer (PC) is one of the most common cancers in male groups worldwide. Long noncoding RNAs (LncRNAs) are reported to be dysregulated in a variety of... 
prostate cancer | GHET1 | cell proliferation | KLF2 | HIF‐1α/Notch‐1 signaling pathway | long non‐coding RNA | long non-coding RNA | HIF-1α/Notch-1 signaling pathway
Journal Article