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Cell Death and Differentiation, ISSN 1350-9047, 2009, Volume 16, Issue 9, pp. 1203 - 1214
Colorectal cancer cell (CRC) fate is governed by an intricate network of signaling pathways, some of which are the direct target of DNA mutations, whereas... 
FoxO | autophagy | ACTIVATED PROTEIN-KINASE | PHOSPHORYLATION | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR | AUTOPHAGIC CELL-DEATH | P38 PATHWAY | HYPOXIA | CELL BIOLOGY | colorectal cancer cell metabolism | COLON-CANCER | CARCINOGENESIS | HIF1 alpha | DIFFERENTIATION | p38 alpha
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2016, Volume 113, Issue 3, pp. E338 - E347
Pathologic extraskeletal bone formation, or heterotopic ossification (HO), occurs following mechanical trauma, burns, orthopedic operations, and in patients... 
Cartilage | Heterotopic ossification | Mesenchymal condensation | HIF1α | Prx | HYPOXIA-INDUCIBLE FACTOR | PX-478 | RISK-FACTORS | MULTIDISCIPLINARY SCIENCES | cartilage | heterotopic ossification | RECEPTOR | mesenchymal condensation | CANCER | HUMAN SKELETAL-MUSCLE | BONE-FORMATION | IN-VIVO | HIF1 alpha | GROWTH-FACTOR | HIF-1-ALPHA | Ossification, Heterotopic - drug therapy | Chondrogenesis - drug effects | Mustard Compounds - pharmacology | Chondrogenesis - genetics | Tendons - drug effects | Humans | Tenotomy | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Luminescent Measurements | Gene Regulatory Networks - drug effects | RNA, Messenger - metabolism | X-Ray Microtomography | Adipose Tissue - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Tendons - surgery | Integrases - metabolism | Burns - complications | Wound Healing - drug effects | Disease Models, Animal | SOX9 Transcription Factor - metabolism | Mesenchymal Stromal Cells - drug effects | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Wounds and Injuries - pathology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | RNA, Messenger - genetics | Wounds and Injuries - complications | Ossification, Heterotopic - diagnostic imaging | Activin Receptors, Type I - metabolism | Sirolimus - pharmacology | Mice, Knockout | Up-Regulation - drug effects | Phenylpropionates - pharmacology | Animals | Signal Transduction - drug effects | Models, Biological | Tendons - pathology | Ossification, Heterotopic - prevention & control | Ossification, Heterotopic - genetics | Adipose Tissue - drug effects | Burns - genetics | Biological Sciences | PNAS Plus
Journal Article
ANTICANCER RESEARCH, ISSN 0250-7005, 03/2019, Volume 39, Issue 3, pp. 1179 - 1184
Background/Aim: Small-cell lung cancer (SCLC) remains one of deadliest types of cancers. Cisdiamminedichloroplatinum (CDDP) is a key chemotherapeutic agent for... 
SCLC | invasion | proliferation | ONCOLOGY | HIF1 alpha | Liprin-alpha 4 | EXPRESSION | PROTEIN-TYROSINE-PHOSPHATASE | FAMILY
Journal Article
Oncogene, ISSN 0950-9232, 04/2014, Volume 33, Issue 16, pp. 2053 - 2064
Journal Article
by Fan, GF and Li, QM and Chan, J
FRONTIERS IN BIOSCIENCE-LANDMARK, ISSN 1093-9946, 03/2019, Volume 24, pp. 1050 - 1059
Vascular remodeling is a critical event following a stroke. It is a well known fact that C1q is the first molecule in the complement classical pathway.... 
Angiogenesis | RECOVERY | C1q | Stroke | ACTIVATION | VEGF | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | HIF1 alpha | RECEPTOR | LAIR1 | CELL BIOLOGY
Journal Article
Nature Cell Biology, ISSN 1465-7392, 01/2016, Volume 18, Issue 2, pp. 213 - 224
Although long non-coding RNAs (lncRNAs) predominately reside in the nucleus and exert their functions in many biological processes, their potential involvement... 
TARGET | HIF-1 | PROTEIN | LONG NONCODING RNAS | TYROSINE KINASE | EPIGENETIC REGULATION | BINDING SITES | HYPOXIA | TUMOR-GROWTH | PROMOTES | CELL BIOLOGY | Heparin-binding EGF-like Growth Factor - pharmacology | Phosphorylation | Prognosis | Membrane Glycoproteins - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | Multiprotein Complexes | Serine | Gene Expression Regulation, Neoplastic | Proline | Cytoplasm - metabolism | E1A-Associated p300 Protein - metabolism | Neoplasm Proteins - metabolism | Receptor, Epidermal Growth Factor - metabolism | Transfection | RNA Interference | Time Factors | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Triple Negative Breast Neoplasms - pathology | Female | Transcription, Genetic | Protein Stability | Protein-Serine-Threonine Kinases - metabolism | Tyrosine | Hydroxylation | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | RNA, Long Noncoding - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Animals | Triple Negative Breast Neoplasms - genetics | Signal Transduction - drug effects | Mice, Nude | Cell Line, Tumor | Glycolysis | RNA, Long Noncoding - metabolism | Index Medicus | glycoprotein non-metastatic b (GPNMB) | Epidermal Growth Factor Receptor (EGFR) | Triple-negative Breast Cancer (TNBC) | Long Noncoding RNA | Signaling Transduction | Glycolysis Reprogramming | HIF1α
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 02/2017, Volume 44, Issue 2, pp. 153 - 161
Journal Article
by Zhang, HS and Du, GY and Zhang, ZG and Zhou, Z and Sun, HL and Yu, XY and Shi, YT and Xiong, DN and Li, H and Huang, YH
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, ISSN 1357-2725, 02/2018, Volume 95, pp. 85 - 92
High aerobic glycolysis not only provides energy to breast cancer cells, but also supports their anabolic growth. The redox sensitive transcription factor NRF2... 
NRF2 | SIGNALING PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | Glycolysis | HIF1 alpha | HYPOXIA | CROSSTALK | Breast cancer cells | CELL BIOLOGY
Journal Article
Anticancer Research, ISSN 0250-7005, 08/2017, Volume 37, Issue 8, pp. 4337 - 4343
Journal Article
International Journal of Cancer, ISSN 0020-7136, 11/2014, Volume 135, Issue 9, pp. 2054 - 2064
Pheochromocytomas and paragangliomas (PPGLs) are catecholamine‐producing chromaffin cell tumors with diverse phenotypic features reflecting mutations in... 
HIF2α | MAX | phenylethanolamine N‐methyltransferase | HIF1α | pheochromocytoma and paraganglioma | phenylethanolamine N-methyltransferase | HYPOXIA-INDUCIBLE FACTOR | TRANSCRIPTIONAL ACTIVITY | TYROSINE-HYDROXYLASE | C-MYC | MAX MUTATIONS | HIF2 alpha | SPORADIC PHEOCHROMOCYTOMA | HIF-2-ALPHA | ONCOLOGY | HIF1 alpha | SDH MUTATIONS | PC12 CELLS | EXPRESSION | Cell Proliferation | Humans | Chromaffin Cells - pathology | Gene Expression Profiling | Basic Helix-Loop-Helix Transcription Factors - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Biomarkers, Tumor - metabolism | Pheochromocytoma - pathology | Cell Differentiation | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Adrenal Gland Neoplasms - pathology | Pheochromocytoma - metabolism | Paraganglioma - pathology | Basic Helix-Loop-Helix Transcription Factors - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Paraganglioma - genetics | RNA, Messenger - genetics | Rats | Mutation - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Chromaffin Cells - metabolism | Animals | Cell Cycle | Paraganglioma - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Adrenal Gland Neoplasms - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Pheochromocytoma - genetics | Biomarkers, Tumor - genetics | Adrenal Gland Neoplasms - genetics | Apoptosis
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/2019, Volume 516, Issue 3, pp. 606 - 612
Hypoxia-inducible factor 1α (HIF1α) activation is profoundly implicated in the initiation and progression of multiple malignant tumors. Prolyl 4-hydroxylase... 
Hypoxia | P4HA1 | HIF1α | Pancreatic cancer | Warburg effect | CELLS | BIOPHYSICS | METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIF1 alpha | EXPRESSION
Journal Article