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1. Full Text Identification and consequences of miRNA-target interactions-beyond repression of gene expression
by Hausser, Jean and Zavolan, Mihaela
Nature Reviews Genetics, ISSN 1471-0056, 2014, Volume 15, Issue 9, pp. 599 - 612
Comparative genomics analyses and high-throughput experimental studies indicate that a microRNA (miRNA) binds to hundreds of sites across the transcriptome.... 
MESSENGER-RNAS | TRANSLATIONAL REPRESSION | WIDE IDENTIFICATION | DNA METHYLATION | AMINO-ACIDS | EMBRYONIC STEM-CELLS | IN-VIVO | GENETICS & HEREDITY | ARGONAUTE BINDING-SITES | MICRORNA TARGETS | PHOTOCHEMICAL ADDITION | Argonaute Proteins - metabolism | Computational Biology - methods | Argonaute Proteins - genetics | Humans | RNA, Messenger - genetics | Gene Expression Regulation | MicroRNAs - metabolism | Gene Regulatory Networks | RNA, Messenger - metabolism | Animals | High-Throughput Screening Assays | Computer Simulation | RNA-Induced Silencing Complex - metabolism | MicroRNAs - genetics | Models, Genetic | Binding Sites | Cell interaction | MicroRNA | Genetic research | Genetic aspects | Research | Properties | Gene expression
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2. High-throughput next generation sequencing
: methods and applications
by Kwon, Young Min and Ricke, Steven C
2011, Methods in molecular biology, ISBN 1617790885, Volume 733., xi, 308
Analyse | Metagenomics | Expression génique | Analysis | Genomes | Gene Expression Profiling | Gene expression | Gene mapping | Genome | Génomes
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3. Full Text Cytosolic expression of functional Fab fragments in Escherichia coli using a novel combination of dual SUMO expression cassette and EnBase® cultivation mode
by Rezaie, F and Davami, F and Mansouri, K and Agha Amiri, S and Fazel, R and Mahdian, R and Davoudi, N and Enayati, S and Azizi, M and Khalaj, V
Journal of Applied Microbiology, ISSN 1364-5072, 07/2017, Volume 123, Issue 1, pp. 134 - 144
AimsThe Escherichia coli expression system is highly effective in producing recombinant proteins. However, there are some limitations in this system,... 
cytosolic expression | functional fab fragment | expression system | E. coli | Fed‐batch culture | recombinant antibody | redox mutant | E. coli redox mutant | E. coli expression system | Fed-batch culture | coli expression system | PROTEIN | ANTIBODY FRAGMENT | OXYGEN-TRANSFER | MICROBIOLOGY | E. COLI | FUSION TECHNOLOGY | HIGH CELL-DENSITY | HIGH-LEVEL EXPRESSION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CYTOPLASM | SINGLE-CHAIN FV | FED-BATCH CULTIVATION | coli redox mutant | Sumo | Endothelial growth factors | Recombinant proteins | Analysis | Escherichia coli | Productivity | Cultivation | Genes | Solubility | Fragments | Cultures | Gene expression | Assaying | Biological activity | Fragmentation | Proteins | Functional anatomy | E coli | Technology | Light chains | Fusion protein | Vascular endothelial growth factor | Folding | Recombinant
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4. Creative expression
: its implications in the educational experiences of adolescents
by Northcutt, Helene B
1964, x, 44
Adolescence | Curricula | High schools | Creation (Literary, artistic, etc.)
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5. Full Text Discrete distributional differential expression (D3E) - a tool for gene expression analysis of single-cell RNA-seq data
by Delmans, Mihails and Hemberg, Martin
BMC Bioinformatics, ISSN 1471-2105, 02/2016, Volume 17, Issue 1, p. 110
The advent of high throughput RNA-seq at the single-cell level has opened up new opportunities to elucidate the heterogeneity of gene expression. One of the... 
Transcriptional bursting model | Stochastic gene expression | Software | Differential gene expression | Single-cell RNA-seq | Sequence Analysis, RNA - methods | Algorithms | Single-Cell Analysis - methods | Humans | Statistical Distributions | Gene Expression Profiling | High-Throughput Nucleotide Sequencing - methods | RNA - genetics | RNA sequencing | Gene expression | Research
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6. Full Text Advanced Glycation End Product 3 (AGE3) Increases Apoptosis and the Expression of Sclerostin by Stimulating TGF-β Expression and Secretion in Osteocyte-Like MLO-Y4-A2 Cells
by Notsu, Masakazu and Kanazawa, Ippei and Takeno, Ayumu and Yokomoto-Umakoshi, Maki and Tanaka, Ken-ichiro and Yamaguchi, Toru and Sugimoto, Toshitsugu
Calcified Tissue International, ISSN 0171-967X, 4/2017, Volume 100, Issue 4, pp. 402 - 411
Advanced glycation end products (AGEs) cause bone fragility due to deterioration in bone quality. We previously reported that AGE3 induced apoptosis and... 
Life Sciences | Biochemistry, general | Advanced Glycation End Products | Orthopedics | Diabetes mellitus | TGF-β | Bone quality | Osteocyte | Endocrinology | Cell Biology | OSTEOBLASTIC DIFFERENTIATION | STROMAL ST2 CELLS | MESENCHYMAL STEM-CELLS | WOMEN | TGF-beta | VERTEBRAL FRACTURES | INCREASED RISK | ENDOCRINOLOGY & METABOLISM | HIGH GLUCOSE | BONE | TYPE-2 DIABETES-MELLITUS | ENDOTHELIAL GROWTH-FACTOR | Cell Line | RANK Ligand - metabolism | Osteocytes - metabolism | Glycoproteins - metabolism | Animals | Transforming Growth Factor beta - genetics | Signal Transduction - drug effects | Bone and Bones - metabolism | Glycation End Products, Advanced - metabolism | Mice | Cell Differentiation - physiology | Transforming Growth Factor beta - metabolism | Apoptosis
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7. Full Text Soluble expression of IGF1 fused to DsbA in SHuffle™ T7 strain: optimization of expression and purification by Box-Behnken design
by Emamipour, Nabbi and Vossoughi, Manouchehr and Mahboudi, Fereidoun and Golkar, Majid and Fard-Esfahani, Pezhman
Applied Microbiology and Biotechnology, ISSN 0175-7598, 4/2019, Volume 103, Issue 8, pp. 3393 - 3406
Production of insulin-like growth factor 1 (IGF1) in Escherichia coli mostly results in the formation of inclusion bodies. In the present study, IGF1 was fused... 
Life Sciences | Biotechnology | Microbiology | Protein purification | Microbial Genetics and Genomics | Soluble expression | Box-Behnken design | Insulin-like growth factor 1 | HPLC | E. coli | INSULIN-LIKE-GROWTH-FACTOR-1 | coli | ESCHERICHIA-COLI | PARAMETERS | RECOMBINANT PROTEIN EXPRESSION | E. COLI | STRATEGIES | OVEREXPRESSION | AFFINITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FUSION PROTEIN | GROWTH-FACTOR-I | NIH 3T3 Cells | Molecular Weight | Insulin-Like Growth Factor I - chemistry | Protein Disulfide-Isomerases - metabolism | Humans | Insulin-Like Growth Factor I - genetics | Chromatography, High Pressure Liquid | Insulin-Like Growth Factor I - isolation & purification | Viral Proteins - metabolism | Recombinant Proteins - isolation & purification | Escherichia coli K12 - metabolism | Cysteine Endopeptidases - metabolism | Industrial Microbiology - methods | Models, Theoretical | Recombinant Proteins - metabolism | Gene Expression | Protein Structure, Secondary | Recombinant Proteins - chemistry | Escherichia coli Proteins - metabolism | Recombinant Proteins - genetics | Protein Disulfide-Isomerases - genetics | Animals | Chromatography, Affinity | Analysis of Variance | Escherichia coli Proteins - genetics | Cell Proliferation - drug effects | Mice | Escherichia coli K12 - genetics | Insulin-Like Growth Factor I - metabolism | Physiological aspects | Protein research | Research | Escherichia coli | Molecular structure | Insulin-like growth factor I | Oxidoreductase | Purity | Response surface methodology | Optimization | Molecular weight | Design optimization | Proteins | E coli | Imidazole | Inclusion bodies | Growth factors | Quality management | Purification | Liquid chromatography | Secondary structure | Sodium chloride | High-performance liquid chromatography | Insulin | Variance analysis | Biological activity | Weight | Protein expression | Yield | Protein structure
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8. Full Text Identification of Key Gene Modules in Human Osteosarcoma by Co‐Expression Analysis Weighted Gene Co‐Expression Network Analysis (WGCNA)
by Liu, Xiangsheng and Hu, Ai‐Xin and Zhao, Jia‐Li and Chen, Feng‐Li
Journal of Cellular Biochemistry, ISSN 0730-2312, 11/2017, Volume 118, Issue 11, pp. 3953 - 3959
Here, we speculated that genes of the module 5 were the essential genes which were associated to human osteosarcoma. Together, our findings provided the... 
GENE EXPRESSION | OSTEOSARCOMA | CO‐EXPRESSION | MODULES | FUNCTION | SURVIVAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | RISK | HIGH-GRADE OSTEOSARCOMA | CO-EXPRESSION | ASSOCIATION | CHEMOTHERAPY | CELL BIOLOGY | Genes, Neoplasm | Humans | Gene Expression Regulation, Neoplastic | Databases, Genetic | Bone Neoplasms - genetics | Osteosarcoma - genetics | Gene Regulatory Networks | Osteosarcoma - metabolism | Bone Neoplasms - metabolism | Genetic research | Osteosarcoma | Analysis | Genes | Enrichment | Antigen presentation | Immune response | Pathogenesis | Modules | Antigen processing | Functional analysis | Gene expression | Bone cancer | Correlation analysis | Network analysis | Biocompatibility | Children | Cancer | Immune system
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9. Full Text Increased inflammatory gene expression in ABC transporter-deficient macrophages: Free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions
by Yvan-Charvet, Laurent and Welch, Carrie and Pagler, Tamara A and Ranalletta, Mollie and Lamkanfi, Mohamed and Han, Seongah and Ishibashi, Minako and Li, Rong and Wang, Nan and Tall, Alan R
Circulation, ISSN 0009-7322, 10/2008, Volume 118, Issue 18, pp. 1837 - 1847
Background-Two macrophage ABC transporters, ABCA1 and ABCG1, have a major role in promoting cholesterol efflux from macrophages. Peritoneal macrophages... 
Lipoproteins | ABC transporters | Inflammation | Cholesterol | Atherosclerosis | atherosclerosis | CARDIAC & CARDIOVASCULAR SYSTEMS | INDUCED APOPTOSIS | CELLULAR CHOLESTEROL | NECROSIS-FACTOR-ALPHA | ABCG1(-/-) BONE-MARROW | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-E | LIPID-ACCUMULATION | EFFLUX | inflammation | ABCA1-DEFICIENT MACROPHAGES | cholesterol | PERIPHERAL VASCULAR DISEASE | MICE | lipoproteins | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Lipoproteins - genetics | Membrane Microdomains - immunology | Signal Transduction - immunology | ATP-Binding Cassette Transporters - genetics | Mice, Mutant Strains | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Mice, Inbred DBA | ATP Binding Cassette Transporter 1 | Macrophages - immunology | Receptors, LDL - genetics | Atherosclerosis - immunology | Atherosclerosis - physiopathology | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Neutrophils - immunology | Receptors, LDL - metabolism | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Cholesterol - metabolism | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Atherosclerosis - metabolism | Macrophages - metabolism | Animals | Lipopolysaccharides - pharmacology | Ligands | Macrophages - drug effects | Mice | ATP-Binding Cassette Transporters - immunology | Lipoproteins - immunology | Physiological aspects | Research | Macrophages | Gene expression | Toll-receptors
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10. Full Text Multiple microRNAs modulate p21Cip1 Waf1 expression by directly targeting its 3′ untranslated region
by Wu, S and Huang, S and Ding, J and Zhao, Y and Liang, L and Liu, T and Zhan, R and He, X
Oncogene, ISSN 0950-9232, 04/2010, Volume 29, Issue 15, pp. 2302 - 2308
Cyclin-dependent kinase inhibitor 1A ( CDKN1A), also known as p21Cip1/Waf1, is a master downstream effector of tumor suppressors.In this study, we... 
P21Cip1/Waf1 | MiRNA | 30 untranslated region | p21Cip1/Waf1 | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | P21 | CELL BIOLOGY | 3 ' untranslated region | ONCOLOGY | GENES | GENETICS & HEREDITY | miRNA | INHIBITOR | KINASES | Cell Cycle - genetics | Cell Line | Multigene Family | Cell Proliferation | Humans | RNA, Messenger - genetics | Gene Expression Regulation | 3' Untranslated Regions - genetics | Genes, Reporter - genetics | RNA, Messenger - metabolism | Luciferases - genetics | Chromosomes, Human, Pair 19 - genetics | Cyclin-Dependent Kinase Inhibitor p21 - genetics | High-Throughput Screening Assays | DNA Mutational Analysis | Base Sequence | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | MicroRNAs - genetics | MicroRNA | Physiological aspects | Tumor suppressor genes | Genetic aspects | Research | Genetic regulation | Cancer | Oncology | Genetics | Mutation | Kinases | Ribonucleic acid--RNA
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11. Full Text Polymorphisms in Arsenic(+III Oxidation State) Methyltransferase (AS3MT) Predict Gene Expression of AS3MT as Well as Arsenic Metabolism
by Karin Engström and Marie Vahter and Simona Jurkovic Mlakar and Gabriela Concha and Barbro Nermell and Rubhana Raqib and Alejandro Cardozo and Karin Broberg and Lund University and Avdelningen för arbets- och miljömedicin and Division of Occupational and Environmental Medicine, Lund University and Lunds universitet
Environmental Health Perspectives, ISSN 0091-6765, 2/2011, Volume 119, Issue 2, pp. 182 - 188
Background: Arsenic (As) occurs as monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) in humans, and the methylation pattern demonstrates large... 
Haplotypes | Urine | Arsenic | Metabolites | P values | Research | Gene expression | Methylation | Metabolism | Genotypes | Blood | AS3MT | BHMT | DNMT3B | DNMT1A | One-carbon metabolism | PEMT | Polymorphism | POPULATION | EARLY-LIFE | polymorphism | arsenic | ARGENTINA | one-carbon metabolism | WOMEN | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | methylation | DNMT3b | DNMT1a | gene expression | SKIN-CANCER | EXPOSURE | DNA (Cytosine-5-)-Methyltransferase 1 | DNA (Cytosine-5-)-Methyltransferases - urine | Humans | Methyltransferases - genetics | Genotype | Male | Chromatography, High Pressure Liquid | Arsenic - toxicity | Phosphatidylethanolamine N-Methyltransferase - genetics | Arsenic - metabolism | Pregnancy | DNA (Cytosine-5-)-Methyltransferases - genetics | Mass Spectrometry | Female | Polymorphism, Genetic - genetics | Betaine-Homocysteine S-Methyltransferase - genetics | Genetic aspects | Methyltransferases | Populations | Genes | Polymethyl methacrylates | Hälsovetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Environmental Health and Occupational Health | Arbetsmedicin och miljömedicin | Health Sciences
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