Physiology & Behavior, ISSN 0031-9384, 2015, Volume 152, Issue Pt B, pp. 363 - 371
Abstract The associations between consumption of a high-fat or ‘Western’ diet and metabolic disorders such as obesity, diabetes, and cardiovascular disease...
Psychiatry | Learning | Animal models | Cognition | Behavior | High-fat diet | Memory | RADIAL-ARM | HIGH-ENERGY DIET | CHRONIC PSYCHOSOCIAL STRESS | MORRIS WATER MAZE | RECEPTOR MESSENGER-RNA | BLOOD-BRAIN-BARRIER | INSULIN-RESISTANCE | BEHAVIORAL SCIENCES | SPATIAL MEMORY | LONG-TERM POTENTIATION | PSYCHOLOGY, BIOLOGICAL | HIGH SATURATED FAT | Diet, High-Fat - adverse effects | Learning - physiology | Animals | Memory - physiology
Psychiatry | Learning | Animal models | Cognition | Behavior | High-fat diet | Memory | RADIAL-ARM | HIGH-ENERGY DIET | CHRONIC PSYCHOSOCIAL STRESS | MORRIS WATER MAZE | RECEPTOR MESSENGER-RNA | BLOOD-BRAIN-BARRIER | INSULIN-RESISTANCE | BEHAVIORAL SCIENCES | SPATIAL MEMORY | LONG-TERM POTENTIATION | PSYCHOLOGY, BIOLOGICAL | HIGH SATURATED FAT | Diet, High-Fat - adverse effects | Learning - physiology | Animals | Memory - physiology
Journal Article
Neuroscience, ISSN 0306-4522, 2013, Volume 253, pp. 110 - 122
Highlights • Western diet (WD) impairs hippocampal-dependent cognitive function in rats. • WD is linked to blood–brain barrier (BBB) and glucoregulatory...
Neurology | saturated fat | energy regulation | dementia | Pavlovian | memory | ketogenic diet | Saturated fat | Energy regulation | Memory | Ketogenic diet | Dementia | HIGH-FAT | HIGH-ENERGY DIET | MIDDLE-AGED RAT | ALZHEIMERS-DISEASE | CHOLESTEROL DIET | LOW-CARBOHYDRATE | SYNAPTIC PLASTICITY | NEUROSCIENCES | BRAIN-BARRIER INTEGRITY | SPATIAL MEMORY | Obesity - chemically induced | Enzyme-Linked Immunosorbent Assay | Glucagon-Like Peptide 1 - metabolism | 3-Hydroxybutyric Acid - blood | Diet, Ketogenic - methods | Rats | Male | Insulin - blood | Conditioning, Classical - physiology | Rats, Sprague-Dawley | Obesity - pathology | Animals | Time Factors | Fasting - blood | Triglycerides - blood | Cognition - physiology | Adiposity - physiology | Blood Glucose - metabolism | Body Weight - physiology | Hippocampus - physiology | Discrimination Learning | Obesity
Neurology | saturated fat | energy regulation | dementia | Pavlovian | memory | ketogenic diet | Saturated fat | Energy regulation | Memory | Ketogenic diet | Dementia | HIGH-FAT | HIGH-ENERGY DIET | MIDDLE-AGED RAT | ALZHEIMERS-DISEASE | CHOLESTEROL DIET | LOW-CARBOHYDRATE | SYNAPTIC PLASTICITY | NEUROSCIENCES | BRAIN-BARRIER INTEGRITY | SPATIAL MEMORY | Obesity - chemically induced | Enzyme-Linked Immunosorbent Assay | Glucagon-Like Peptide 1 - metabolism | 3-Hydroxybutyric Acid - blood | Diet, Ketogenic - methods | Rats | Male | Insulin - blood | Conditioning, Classical - physiology | Rats, Sprague-Dawley | Obesity - pathology | Animals | Time Factors | Fasting - blood | Triglycerides - blood | Cognition - physiology | Adiposity - physiology | Blood Glucose - metabolism | Body Weight - physiology | Hippocampus - physiology | Discrimination Learning | Obesity
Journal Article
Proceedings of the Nutrition Society, ISSN 0029-6651, 05/2017, Volume 76, Issue 4, pp. 1 - 11
There is increasing evidence for important roles of key cognitive processes, including attention, memory and learning, in the short-term decision making about...
Obesity | Cognition | Diet | Memory | HIGH-ENERGY DIET | HIPPOCAMPAL-DEPENDENT MEMORY | NUTRITION & DIETETICS | ATTENTION BIAS | INSULIN-RESISTANCE | BODY-MASS INDEX | BRAIN-BARRIER INTEGRITY | CORONARY-HEART-DISEASE | SATURATED FAT | REGULATES FOOD-INTAKE | WESTERN-STYLE DIET | Eating - psychology | Dietary Fats - adverse effects | Diet, Western - psychology | Obesity - psychology | Humans | Diet, High-Fat - adverse effects | Obesity - physiopathology | Cognitive Dysfunction - etiology | Diet, Western - adverse effects | Dietary Sugars - adverse effects | Animals | Diet, High-Fat - psychology | Obesity - etiology | Hippocampus - physiopathology | Body weight | Cognitive ability | Neurogenesis | High fat diet | Learning | Hunger | Blood-brain barrier | Rodents | Sugar | Food | Appetite | Decision making | Inflammation | Fatty acids | Studies | Nutrition research | Brain-derived neurotrophic factor | Cognition & reasoning | Dietary fiber | Cognitive tasks | Hippocampus
Obesity | Cognition | Diet | Memory | HIGH-ENERGY DIET | HIPPOCAMPAL-DEPENDENT MEMORY | NUTRITION & DIETETICS | ATTENTION BIAS | INSULIN-RESISTANCE | BODY-MASS INDEX | BRAIN-BARRIER INTEGRITY | CORONARY-HEART-DISEASE | SATURATED FAT | REGULATES FOOD-INTAKE | WESTERN-STYLE DIET | Eating - psychology | Dietary Fats - adverse effects | Diet, Western - psychology | Obesity - psychology | Humans | Diet, High-Fat - adverse effects | Obesity - physiopathology | Cognitive Dysfunction - etiology | Diet, Western - adverse effects | Dietary Sugars - adverse effects | Animals | Diet, High-Fat - psychology | Obesity - etiology | Hippocampus - physiopathology | Body weight | Cognitive ability | Neurogenesis | High fat diet | Learning | Hunger | Blood-brain barrier | Rodents | Sugar | Food | Appetite | Decision making | Inflammation | Fatty acids | Studies | Nutrition research | Brain-derived neurotrophic factor | Cognition & reasoning | Dietary fiber | Cognitive tasks | Hippocampus
Journal Article
Life Sciences, ISSN 0024-3205, 08/2014, Volume 110, Issue 2, pp. 53 - 60
It has been suggested that obesity triggered by consuming a high-fat diet (HF) can account for oxidative damage and mitochondrial dysfunction. Thus, we aim to...
Diet-resistant rats | Mitochondrial dysfunction | Diet-induced obese rat | Oxidative damage | High-fat diet | LEPTIN | MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | HIGH-ENERGY DIET | DEMENTIA | GHRELIN | BARRIER INTEGRITY | RISK | DISEASES | MIDLIFE | PHARMACOLOGY & PHARMACY | STRESS | Malondialdehyde - metabolism | Mitochondrial Diseases - pathology | Enzyme-Linked Immunosorbent Assay | Obesity - complications | Brain - physiopathology | Oxidative Stress - physiology | Diet, High-Fat - adverse effects | Rats | Male | Rats, Sprague-Dawley | Lipid Peroxidation - physiology | Mitochondrial Diseases - etiology | Catalase - metabolism | Ghrelin - metabolism | Neuropeptide Y - metabolism | Animals | Obesity - etiology | Antioxidants - analysis | Obesity | Index Medicus
Diet-resistant rats | Mitochondrial dysfunction | Diet-induced obese rat | Oxidative damage | High-fat diet | LEPTIN | MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | HIGH-ENERGY DIET | DEMENTIA | GHRELIN | BARRIER INTEGRITY | RISK | DISEASES | MIDLIFE | PHARMACOLOGY & PHARMACY | STRESS | Malondialdehyde - metabolism | Mitochondrial Diseases - pathology | Enzyme-Linked Immunosorbent Assay | Obesity - complications | Brain - physiopathology | Oxidative Stress - physiology | Diet, High-Fat - adverse effects | Rats | Male | Rats, Sprague-Dawley | Lipid Peroxidation - physiology | Mitochondrial Diseases - etiology | Catalase - metabolism | Ghrelin - metabolism | Neuropeptide Y - metabolism | Animals | Obesity - etiology | Antioxidants - analysis | Obesity | Index Medicus
Journal Article
Obesity Reviews, ISSN 1467-7881, 12/2014, Volume 15, Issue 12, pp. 996 - 1007
Summary Male fertility is declining in developed countries, as well as in developing countries. External factors linked to lifestyle, such as eating disorders,...
testicular metabolism | spermatogenesis | male fertility | High‐energy diets | High-energy diets | Testicular metabolism | Male fertility | Spermatogenesis | OXIDATIVE STRESS | BLOOD-TESTIS | FATTY-ACIDS | GLUCOSE TRANSPORTERS | TESTICULAR GERM-CELLS | SEMEN QUALITY | ENDOCRINOLOGY & METABOLISM | BISPHENOL-A | RAT SERTOLI-CELLS | CELLULAR-LOCALIZATION | ACROSOME REACTION | Spermatozoa - chemistry | Life Style | Testis - metabolism | Reactive Oxygen Species - metabolism | Oxidative Stress | Diet - adverse effects | Obesity - complications | Humans | Infertility, Male - etiology | Feeding Behavior | Male | Energy Intake | Infertility, Male - physiopathology | DNA - analysis | Spermatozoa - physiology | DNA Damage | Lipids - analysis | Mitochondria - physiology
testicular metabolism | spermatogenesis | male fertility | High‐energy diets | High-energy diets | Testicular metabolism | Male fertility | Spermatogenesis | OXIDATIVE STRESS | BLOOD-TESTIS | FATTY-ACIDS | GLUCOSE TRANSPORTERS | TESTICULAR GERM-CELLS | SEMEN QUALITY | ENDOCRINOLOGY & METABOLISM | BISPHENOL-A | RAT SERTOLI-CELLS | CELLULAR-LOCALIZATION | ACROSOME REACTION | Spermatozoa - chemistry | Life Style | Testis - metabolism | Reactive Oxygen Species - metabolism | Oxidative Stress | Diet - adverse effects | Obesity - complications | Humans | Infertility, Male - etiology | Feeding Behavior | Male | Energy Intake | Infertility, Male - physiopathology | DNA - analysis | Spermatozoa - physiology | DNA Damage | Lipids - analysis | Mitochondria - physiology
Journal Article
Appetite, ISSN 0195-6663, 04/2013, Volume 63, pp. 119 - 128
► Western diets tend to be high in saturated fat and simple carbohydrates (HFS). ► This review examines the impact of HFS diets on the human brain. ► HFS diets...
Executive function | Memory | Cognitive | Saturated fat | Sugar | Western diet | Hedonic | OXIDATIVE STRESS | HIGH-ENERGY DIET | MESSENGER-RNA EXPRESSION | HIGH-FAT DIET | NEUROTROPHIC FACTOR | PREFRONTAL CORTEX | NUTRITION & DIETETICS | INSULIN-RESISTANCE | BEHAVIORAL SCIENCES | CORONARY-HEART-DISEASE | HIGH SATURATED FAT | PARKINSONS-DISEASE | Fatty Acids - adverse effects | Memory - drug effects | Dietary Fats - adverse effects | Animals | Neurodegenerative Diseases - physiopathology | Diet | Neurodegenerative Diseases - etiology | Humans | Dietary Fats - administration & dosage | Fatty Acids - administration & dosage | Hippocampus - drug effects | Cognition - drug effects | Lipids | Brain damage | Cognition
Executive function | Memory | Cognitive | Saturated fat | Sugar | Western diet | Hedonic | OXIDATIVE STRESS | HIGH-ENERGY DIET | MESSENGER-RNA EXPRESSION | HIGH-FAT DIET | NEUROTROPHIC FACTOR | PREFRONTAL CORTEX | NUTRITION & DIETETICS | INSULIN-RESISTANCE | BEHAVIORAL SCIENCES | CORONARY-HEART-DISEASE | HIGH SATURATED FAT | PARKINSONS-DISEASE | Fatty Acids - adverse effects | Memory - drug effects | Dietary Fats - adverse effects | Animals | Neurodegenerative Diseases - physiopathology | Diet | Neurodegenerative Diseases - etiology | Humans | Dietary Fats - administration & dosage | Fatty Acids - administration & dosage | Hippocampus - drug effects | Cognition - drug effects | Lipids | Brain damage | Cognition
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2014, Volume 40, pp. 9 - 17
Abstract In addition to metabolic and cardiovascular disorders, obesity pandemic is associated with chronic low-grade inflammation as well as adverse cognitive...
Psychiatry | Allergy and Immunology | Adolescence | Obesity | Cytokines | Memory | Spatial learning | Hippocampus | Overweight | LONG-TERM | HIGH-ENERGY DIET | RELATIONAL MEMORY | ADULT NEUROGENESIS | WEIGHT-LOSS | IMMUNOLOGY | NEUROSCIENCES | IMMUNE-SYSTEM | BRAIN-BARRIER INTEGRITY | SPATIAL MEMORY | DUAL ROLE | WORKING-MEMORY | Eating | Hippocampus - immunology | Maze Learning - physiology | Rats, Wistar | Obesity - immunology | Spatial Memory - physiology | Diet, High-Fat - adverse effects | Rats | Encephalitis - immunology | Male | Obesity - physiopathology | Memory, Short-Term - physiology | Memory, Long-Term - physiology | Animals | Brain - immunology | Cytokines - blood | Memory - physiology | Inflammation
Psychiatry | Allergy and Immunology | Adolescence | Obesity | Cytokines | Memory | Spatial learning | Hippocampus | Overweight | LONG-TERM | HIGH-ENERGY DIET | RELATIONAL MEMORY | ADULT NEUROGENESIS | WEIGHT-LOSS | IMMUNOLOGY | NEUROSCIENCES | IMMUNE-SYSTEM | BRAIN-BARRIER INTEGRITY | SPATIAL MEMORY | DUAL ROLE | WORKING-MEMORY | Eating | Hippocampus - immunology | Maze Learning - physiology | Rats, Wistar | Obesity - immunology | Spatial Memory - physiology | Diet, High-Fat - adverse effects | Rats | Encephalitis - immunology | Male | Obesity - physiopathology | Memory, Short-Term - physiology | Memory, Long-Term - physiology | Animals | Brain - immunology | Cytokines - blood | Memory - physiology | Inflammation
Journal Article
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Full Text
Putting the diet back into diet-induced obesity: Diet-induced hypothalamic gene expression
European Journal of Pharmacology, ISSN 0014-2999, 2008, Volume 585, Issue 1, pp. 31 - 37
A wealth of detailed mechanistic information relating to obesity and body weight regulation has emerged from study of single gene mutation models, and...
Neuropeptide Y | Agouti-related peptide | Leptin | Sprague Dawley rat | SPRAGUE-DAWLEY RATS | HIGH-ENERGY DIET | FOOD-INTAKE | neuropeptide Y | EARLY-ONSET OBESITY | HIGH-FAT DIETS | leptin | RESISTANT RATS | BODY-WEIGHT | NEUROPEPTIDE-Y EXPRESSION | agouti-related peptide | PHARMACOLOGY & PHARMACY | LIQUID ENSURE | LEPTIN RECEPTOR | Animals | Hypothalamus - metabolism | Diet | Energy Metabolism | Humans | Gene Expression Regulation | Rats | Obesity - physiopathology | Obesity - genetics | Rats, Sprague-Dawley | Disease Models, Animal | Obesity - metabolism | Obesity | Brain | Analysis | Genes | Body weight | Genetic research | Gene expression
Neuropeptide Y | Agouti-related peptide | Leptin | Sprague Dawley rat | SPRAGUE-DAWLEY RATS | HIGH-ENERGY DIET | FOOD-INTAKE | neuropeptide Y | EARLY-ONSET OBESITY | HIGH-FAT DIETS | leptin | RESISTANT RATS | BODY-WEIGHT | NEUROPEPTIDE-Y EXPRESSION | agouti-related peptide | PHARMACOLOGY & PHARMACY | LIQUID ENSURE | LEPTIN RECEPTOR | Animals | Hypothalamus - metabolism | Diet | Energy Metabolism | Humans | Gene Expression Regulation | Rats | Obesity - physiopathology | Obesity - genetics | Rats, Sprague-Dawley | Disease Models, Animal | Obesity - metabolism | Obesity | Brain | Analysis | Genes | Body weight | Genetic research | Gene expression
Journal Article
Frontiers in Behavioral Neuroscience, ISSN 1662-5153, 01/2017, Volume 11, p. 9
Consumption of a Western Diet (WD) that is high in saturated fat and added sugars negatively impacts cognitive function, particularly mnemonic processes that...
Fat | Neuroinflammation | Endotoxin | Insulin | Gut bacteria | Hippocampus | Sugar | HIPPOCAMPAL SYNAPTIC PLASTICITY | LONG-TERM-MEMORY | HIGH-ENERGY DIET | insulin | hippocampus | HIGH-FAT DIET | NEUROTROPHIC FACTOR | gut bacteria | NEUROSCIENCES | STREPTOZOTOCIN-DIABETIC RATS | GLUCAGON-LIKE PEPTIDE-1 | DEPENDENT RELATIONAL MEMORY | neuroinflammation | INSULIN-RESISTANCE | fat | BEHAVIORAL SCIENCES | sugar | INDUCED OBESITY | endotoxin | Physiological aspects | Cognition disorders | Diet | Microbiota (Symbiotic organisms) | Health aspects | Dysbacteriosis | Memory | Cognitive ability | Microbiomes | Cognition | High fat diet | Microbiota | Blood-brain barrier | Intestine | Rodents | Bacteria | Digestive tract | Carbohydrates | Obesity | Digestive system | Gastrointestinal tract | Inflammation | Permeability | Metabolism | Probiotics | Antibiotics | Insulin resistance | Diabetes | Animal cognition
Fat | Neuroinflammation | Endotoxin | Insulin | Gut bacteria | Hippocampus | Sugar | HIPPOCAMPAL SYNAPTIC PLASTICITY | LONG-TERM-MEMORY | HIGH-ENERGY DIET | insulin | hippocampus | HIGH-FAT DIET | NEUROTROPHIC FACTOR | gut bacteria | NEUROSCIENCES | STREPTOZOTOCIN-DIABETIC RATS | GLUCAGON-LIKE PEPTIDE-1 | DEPENDENT RELATIONAL MEMORY | neuroinflammation | INSULIN-RESISTANCE | fat | BEHAVIORAL SCIENCES | sugar | INDUCED OBESITY | endotoxin | Physiological aspects | Cognition disorders | Diet | Microbiota (Symbiotic organisms) | Health aspects | Dysbacteriosis | Memory | Cognitive ability | Microbiomes | Cognition | High fat diet | Microbiota | Blood-brain barrier | Intestine | Rodents | Bacteria | Digestive tract | Carbohydrates | Obesity | Digestive system | Gastrointestinal tract | Inflammation | Permeability | Metabolism | Probiotics | Antibiotics | Insulin resistance | Diabetes | Animal cognition
Journal Article
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 08/2018, Volume 315, Issue 2, pp. R255 - R266
Easy access to high-energy food has been linked to high rates of obesity in the world. Understanding the way that access to palatable (high fat or high...
Rats | High-energy diet | Palatability | Predictive model | VARIETY | MEAL PATTERNS | PHYSIOLOGY | predictive model | FOOD-INTAKE | high-energy diet | CAFETERIA DIET | BODY-WEIGHT | RESPONSES | OBESITY | rats | SELECTION | REWARD SENSITIVITY | palatability | Obesity | Models | Diet therapy | Animal models in research | Patient outcomes | Methods
Rats | High-energy diet | Palatability | Predictive model | VARIETY | MEAL PATTERNS | PHYSIOLOGY | predictive model | FOOD-INTAKE | high-energy diet | CAFETERIA DIET | BODY-WEIGHT | RESPONSES | OBESITY | rats | SELECTION | REWARD SENSITIVITY | palatability | Obesity | Models | Diet therapy | Animal models in research | Patient outcomes | Methods
Journal Article