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1. Full Text Oesophageal cancer in Golestan Province, a high-incidence area in northern Iran – A review
by Islami, Farhad and Kamangar, Farin and Nasrollahzadeh, Dariush and Møller, Henrik and Boffetta, Paolo and Malekzadeh, Reza
European Journal of Cancer, ISSN 0959-8049, 2009, Volume 45, Issue 18, pp. 3156 - 3165
Abstract Golestan Province, located in the south-east littoral of the Caspian Sea in northern Iran, has one of the highest rates of oesophageal cancer (OC) in... 
Hematology, Oncology and Palliative Medicine | Adenocarcinoma | Carcinoma | Iran | squamous cell | Oesophageal neoplasms | Review | Epidemiology | Risk factors | Carcinoma, squamous cell | POPULATION | NORTHEASTERN IRAN | GENETIC POLYMORPHISMS | TP53 MUTATIONS | GASTRIC CANCERS | HIGH-RISK AREA | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | TOOTH LOSS | HELICOBACTER-PYLORI | DRINKING-WATER | Esophageal Neoplasms - etiology | Smoking - adverse effects | Hot Temperature - adverse effects | Carcinoma, Squamous Cell - epidemiology | Tobacco, Smokeless - adverse effects | Humans | Risk Factors | Male | Alcohol Drinking - adverse effects | Turkmenistan - ethnology | Alphapapillomavirus - isolation & purification | Esophageal Neoplasms - epidemiology | Malnutrition - complications | Opioid-Related Disorders - epidemiology | Asia - epidemiology | Carcinoma, Squamous Cell - etiology | Alcohol Drinking - epidemiology | Smoking - epidemiology | Female | Polymorphism, Genetic - genetics | Water Supply | Iran - epidemiology | Opioid-Related Disorders - complications
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2. Full Text Distribution of N-nitrosamines in drinking water and human urinary excretions in high incidence area of esophageal cancer in Huai'an, China
by Zhao, Chao and Lu, Qiang and Gu, Yun and Pan, Enchun and Sun, Zhongming and Zhang, Hu and Zhang, Ying and Zhou, Jingjing and Du, Ying and Feng, Yuanmei and Liu, Ran and Pu, Yuepu and Yin, Lihong
Chemosphere, ISSN 0045-6535, 11/2019, Volume 235, pp. 288 - 296
The Huai'an area in Jiangsu Province of East China is an endemic region of esophageal cancer (EC). The regional heterogeneity of EC suggests that the levels of... 
Drinking water | N-Nitrosamines | High incidence area | Human urine | Esophageal cancer | NITRATE | STATISTICS | RISK | TANDEM MASS-SPECTROMETRY | NITROSO COMPOUNDS | ENVIRONMENTAL SCIENCES | VOLATILE NITROSAMINES | ASSOCIATION | PRECURSORS | EXPOSURE | FOOD | Nitrosoamines | Index Medicus
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3. Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high-incidence area of northern China
by Zhao, F and Su, JF and Lun, SM and Hou, YJ and Duan, LJ and Wang, NC and Shen, FF and Zhang, YW and Gao, ZW and Li, J and Du, XJ and Zhou, FY
ONCOLOGY LETTERS, ISSN 1792-1074, 08/2019, Volume 18, Issue 2, pp. 1267 - 1277
Metabolic gene variants, smoking, and alcohol consumption are important upper digestive tract cancer (UDTC) risk factors. However, the gene-gene and... 
METAANALYSIS | GSTM1 | GASTRIC-CANCER RISK | SUSCEPTIBILITY | gene polymorphism | alcohol drinking | upper digestive cancer | LUNG-CANCER | ONCOLOGY | CYTOCHROME-P450 2E1 | high-incidence area | smoking | JAPANESE | ESOPHAGEAL CANCER | CYP2E1
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4. Full Text Helicobacter pylori babA2 positivity predicts risk of gastric cancer in Ardabil, a very high-risk area in Iran
by Abdi, Esmat and Latifi-Navid, Saeid and Yazdanbod, Abbas and Zahri, Saber
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2016, Volume 17, Issue 2, pp. 733 - 738
Ardabil, Iran | H. pylori | BabA2 | High-incidence | Gastric cancer | CagA
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5. Full Text Diverse H. pylori strains, IL-10 promoter polymorphisms with high morbidity of gastric cancer in Hexi area of Gansu Province, China
by Zeng, Xiangting and Zeng, Xiangting and Li, Yumin and Li, Yumin and Liu, Tao and Liu, Tao and Zhang, Junqiang and Zhang, Junqiang
Molecular and Cellular Biochemistry, ISSN 0300-8177, 3/2012, Volume 362, Issue 1, pp. 241 - 248
In Hexi area of Gansu Province, people have a higher susceptibility of gastric cancer than people in the rest area of China. There is substantial geographic... 
Life Sciences | Biochemistry, general | High incidence | IL-10 promoter polymorphism | Medical Biochemistry | Oncology | Cardiology | H. pylori infection | Gastric cancer | RISK | NECROSIS-FACTOR-ALPHA | COLONIZATION | CYTOKINE GENE POLYMORPHISMS | CELL BIOLOGY | INFLAMMATION | INFECTION | SECRETION | HELICOBACTER-PYLORI | ASSOCIATION | EPIDEMIOLOGY | Stomach Neoplasms - genetics | Promoter Regions, Genetic | Genetic Predisposition to Disease | Humans | Middle Aged | Genotype | Helicobacter pylori - classification | Male | China - epidemiology | Stomach Neoplasms - microbiology | Interleukin-10 - genetics | Aged, 80 and over | Adult | Female | Stomach Neoplasms - epidemiology | Aged | Polymorphism, Single Nucleotide | Helicobacter Infections - microbiology | Infection | Helicobacter pylori | Genes | DNA | Development and progression | Helicobacter infections | Genetic aspects | Health aspects | Stomach cancer | Cancer | Gastrointestinal diseases | Biological diversity | Polymorphism | Haplotypes | Typing | Antibodies | Immunoblotting | Environmental factors | Geographical variations | Gene polymorphism | Population genetics | Morbidity | Risk factors | Interleukin 10
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6. Tuberculosis transmission patterns in a high-incidence area: A spatial analysis
by Munch, Z and Van Lill, S.W.P and Booysen, C.N and Zietsman, H.L and Enarson, D.A and Beyers, N
International Journal of Tuberculosis and Lung Disease, ISSN 1027-3719, 03/2003, Volume 7, Issue 3, pp. 271 - 277
SETTING: In the Cape Town suburbs of Ravensmead and Uitsig, tuberculosis has reached epidemic levels, with notifications of 1340/100000 in 1996. These suburbs... 
Shebeens | Spatial analysis | High incidence | Alcohol | Tuberculosis | alcohol | MYCOBACTERIUM-TUBERCULOSIS | INFECTIOUS DISEASES | high incidence | tuberculosis | shebeens | AFRICA | spatial analysis | GEOGRAPHICAL INFORMATION-SYSTEM | COMMUNITY | RESPIRATORY SYSTEM | DYNAMICS | DIRECTLY OBSERVED THERAPY | MOLECULAR EPIDEMIOLOGY | OUTBREAK | Tuberculosis - epidemiology | Geographic Information Systems | Demography | Humans | Risk Factors | South Africa - epidemiology | Tuberculosis - etiology | Male | Unemployment | Crowding | Socioeconomic Factors | Incidence | Adult | Female | Tuberculosis - transmission | Cluster Analysis
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7. Full Text Effect of riboflavin-fortified salt nutrition intervention on esophageal squamous cell carcinoma in a high incidence area, China
by He, Yutong and Ye, Li and Shan, Baoen and Song, Guohui and Meng, Fanshu and Wang, Shijie
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2009, Volume 10, Issue 4, pp. 619 - 622
Background: Riboflavin-fortified salt is now supplied in the diet for residents who live in high incidence areas for esophageal squamous cell carcinoma in... 
Intervention | Riboflavin | Fortified salt | High incidence area | Esophageal SCC | riboflavin-fortified salt | ONCOLOGY | high incidence area | intervention | CANCER | DEFICIENCY
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8. Full Text High‐temperature beverages and foods and esophageal cancer risk—A systematic review
by Islami, Farhad and Boffetta, Paolo and Ren, Jian‐Song and Pedoeim, Leah and Khatib, Dara and Kamangar, Farin
International Journal of Cancer, ISSN 0020-7136, 08/2009, Volume 125, Issue 3, pp. 491 - 524
Coffee, tea and maté may cause esophageal cancer (EC) by causing thermal injury to the esophageal mucosa. If so, the risk of EC attributable to thermal injury... 
tea | esophageal cancer | review | coffee | temperature | cohort | adenocarcinoma | maté | case–control | squamous cell carcinoma | Adenocarcinoma | Tea | Squamous cell carcinoma | Temperature | Cohort | Review | Coffee | Maté | Esophageal cancer | Case-control | LIFE-STYLE FACTORS | case-control | POLYCYCLIC AROMATIC-HYDROCARBONS | COFFEE CONSUMPTION | UPPER AERODIGESTIVE TRACT | GREEN TEA CONSUMPTION | HIGH-EPIDEMIC AREA | JIANGSU PROVINCE | MATE DRINKING | ONCOLOGY | mate | SQUAMOUS-CELL CARCINOMA | HIGH-INCIDENCE AREA | Esophageal Neoplasms - etiology | Prospective Studies | Age Factors | Hot Temperature - adverse effects | Risk Assessment | Adenocarcinoma - etiology | Humans | Risk Factors | Case-Control Studies | Esophageal Neoplasms - epidemiology | Carcinoma, Squamous Cell - etiology | Mucous Membrane - injuries | Sex Factors | Beverages | Odds Ratio | Food
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9. Full Text Aldehyde dehydrogenases in cancer: an opporunity for biomaker and drug development?
by Pors, K and Moreb, JS
DRUG DISCOVERY TODAY, ISSN 1359-6446, 12/2014, Volume 19, Issue 12, pp. 1953 - 1963
Aldehyde dehydrogenases (ALDHs) belong to a superfamily of 19 isozymes that are known to participate in many physiologically important biosynthetic processes... 
BREAST-CANCER | MOLECULAR CHARACTERIZATION | DUOCARMYCIN ANALOGS | SUBSTRATE-SPECIFICITY | RETINOIC ACID | PHARMACOLOGY & PHARMACY | ALDH1 EXPRESSION | ACUTE MYELOID-LEUKEMIA | PROGNOSTIC-SIGNIFICANCE | HIGH-INCIDENCE AREA | STEM-CELL MARKER
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10. Extent of transmission captured by contact tracing in a tuberculosis high endemic setting
by Bjorn-Mortensen, Karen and Lillebaek, Troels and Koch, Anders and Soborg, Bolette and Ladefoged, Karin and Sørensen, Hans Christian Florian and Kohl, Thomas Andreas and Niemann, Stefan and Andersen, Aase Bengaard
European Respiratory Journal, ISSN 0903-1936, 03/2017, Volume 49, Issue 3, pp. 1601851 - 1601851
We have previously documented a high incidence of tuberculosis (TB) (>1000 per 100 000 inhabitants) and considerable Mycobacterium tuberculosis transmission in... 
EAST GREENLAND | TB TRANSMISSION | RESPIRATORY SYSTEM | HIGH-INCIDENCE AREA | Contact tracing | Disease transmission | Tuberculosis | Isoniazid
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11. Full Text Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54
by Song, Xin and Li, Xing-Chuan and Li, Hong-Lei and Guo, Ming and Kong, Qing-Peng and Ku, Jian-Wei and Liu, Hai and Li, Feng and Wang, Wei-Peng and Liu, Hai-Lin and Yuan, Ling and Liu, Na and Zuo, Xian-Bo and Cui, Wen-Yan and Xie, Dong and Ji, Ai-Fang and Chen, Jie and Gao, She-Gan and Chen, Shu-Qing and Zhou, Ying-Fa and Xing, Guo-Lan and Shen, Fang-Fang and Chen, Bao-Ping and Yuan, Zhi-Qing and Hong, Jun-Yan and Han, Suo-Li and Wang, Zhou and Cao, Wei-Ke and Miao, Jian-Jun and Fan, Zeng-Lin and Tian, Jin-Ya and Sheyhidin, Ilyar and Zhu, Wen-Liang and Wang, Jin-Sheng and Zhang, Xue-Jun and Zheng, Hou-Feng and Huang, Jing and Zhuang, Xiang and Wang, Tian-Yun and Cui, Juan and Dong, Zi-Ming and Wang, Hai-Yan and Wei, Wu and Zhou, Qi and Wang, Jin and Jin, Yan and Feng, Xiao-Shan and Xu, Li-Yan and Chen, Long-Qi and Wu, Zhi-Yong and Lin, Ruo-Bai and Zhou, Fu-You and Guo, Tao and Wang, Han-Jing and Dong, Jin-Cheng and Lu, Xiao-Mei and Wang, Li-Dong and Qi, Hong and Wu, Yue and Lu, Yue and Chang, Fu-Bao and Cai, Zhi-Ming and Fan, Dong-Mei and Fan, Zong-Min and Gao, Fu-Sheng and Gao, Wen-Jun and Jiao, Xin-Ying and Chang, Zhi-Wei and Lian, Shi-Yong and Han, Min and Lan, Yu and Huang, Jia and Zhang, Peng and Yang, Liu-Qin and Bao, Zhi-Qin and Wang, Liang and Chen, Zhi-Guo and Shen, Zhong-Ying and Li, Dan and Yuan, Chao and Zhang, Qin-Xian and Song, Shuang and Liu, Tai-Jiang and Li, Yin and Qige, Qirenwang and Zhu, Fu-Guo and Yang, Wan-Cai and Sun, Liang-Dan and Lu, Qin and Zhang, Zheng and Fu, Wen-Jing and Yang, Wen-Jun and Guo, Zhi-Gang and Yue, Wen-Bin and Ren, Jing-Li and Zhang, Yan-Rui and Fan, Yu-Jing and Wang, Jian-Po and Ren, Shu-Wei and Yang, Jie-Zhi and ...
Nature Genetics, ISSN 1061-4036, 09/2010, Volume 42, Issue 9, pp. 759 - 763
We performed a genome-wide association study of esophageal squamous cell carcinoma (ESCC) by genotyping 1,077 individuals with ESCC and 1,733 control subjects... 
NORTHERN CHINA | RISK-FACTORS | GENETICS & HEREDITY | PHOSPHOLIPASE-C-EPSILON | FUNCTIONAL-CHARACTERIZATION | HAN CHINESE | CANCER | HIGH-INCIDENCE AREA | Genetic Predisposition to Disease | Genome-Wide Association Study | Membrane Proteins - genetics | Carcinoma, Squamous Cell - genetics | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Esophageal Neoplasms - ethnology | Polymorphism, Single Nucleotide - physiology | Male | Genetic Loci | Case-Control Studies | Carcinoma, Squamous Cell - ethnology | Esophageal Neoplasms - genetics | Phosphoinositide Phospholipase C - genetics | Membrane Transport Proteins | Female | Aged | Chromosomes, Human, Pair 20 | Chromosomes, Human, Pair 10 | Care and treatment | Genetic aspects | Disease susceptibility | Research | Single nucleotide polymorphisms | Health aspects | Esophageal cancer | Risk factors
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12. Full Text Primary Screening for Breast Diseases among 17618 Women in Wufeng Area, a Region with High Incidence of Cervical Cancer in China
by 张庆华 刘眈 黄传英 胡婷 沈健 胡美玲 杨茹 陈枝岚 来主会 刘桂玲 梅业冬 向群英 李雄 黄科程 王少帅 潘秀玉 严玉婷 李夜 陈茜 奚玲 邓东锐 汪辉 王世宣 卢运萍 马丁 李双
华中科技大学学报：医学英德文版, ISSN 1672-0733, 2012, Volume 32, Issue 2, pp. 252 - 256
In this study, the current status for breast diseases in a region with high-incidence of cervical cancer were epidemiologically investigated. From March to... 
screening | high-incidence | cervical | diseases | cancer | region | breast | high-incidence region | breast diseases | Medicine & Public Health | Medicine/Public Health, general | cervical cancer | Screening | Breast diseases | Cervical cancer | High-incidence region | RISK | BIOCHEMISTRY & MOLECULAR BIOLOGY | Age Distribution | Uterine Cervical Neoplasms - diagnosis | Comorbidity | Humans | Middle Aged | Risk Factors | Uterine Cervical Neoplasms - epidemiology | Mass Screening - statistics & numerical data | Breast Diseases - epidemiology | China - epidemiology | Incidence | Adolescent | Breast Diseases - diagnosis | Aged, 80 and over | Adult | Female | Aged | Women | Analysis | Oncology, Experimental | Breast cancer | Mammography | Diagnosis | Research | Medical screening | Cancer
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13. Full Text Development of esophageal cancer in Chaoshan region, China: Association with environmental, genetic and cultural factors
by Tang, W.R and Chen, Z.J and Lin, Kun and Su, Min and Au, W.W
International Journal of Hygiene and Environmental Health, ISSN 1438-4639, 01/2015, Volume 218, Issue 1, pp. 12 - 18
Esophageal squamous cell carcinoma (ESCC) is the eighth most common cancer by incidence worldwide. Although the cancer is located at a readily recognizable and... 
Alcohol consumption | Familial cancer | Genetic susceptibility | Cigarette smoking | Esophageal cancer | LIFE-STYLE FACTORS | INFECTIOUS DISEASES | POLYMORPHISM | HEAT-SHOCK PROTEINS | GREEN TEA | TOBACCO SMOKING | HIGH-RISK AREA | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | SQUAMOUS-CELL CARCINOMA | ALCOHOL-DRINKING | HIGH-INCIDENCE AREA | GEOGRAPHIC REGIONS | Esophageal Neoplasms - etiology | Carcinoma, Squamous Cell - etiology | Genetic Predisposition to Disease | Esophageal Neoplasms - genetics | Carcinoma, Squamous Cell - epidemiology | Carcinoma, Squamous Cell - genetics | Humans | Risk Factors | China - epidemiology | Environmental Exposure | Esophageal Neoplasms - epidemiology | Incidence | Squamous cell carcinoma | Mortality | Development and progression | Medicine, Preventive | Risk factors | Preventive health services | Index Medicus
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14. Full Text Increase in the Incidence of Differentiated Thyroid Carcinoma in Children, Adolescents, and Young Adults: A Population-Based Study
by Vergamini, Lucas Bonachi and Frazier, A. Lindsay, MD, MSc and Abrantes, Fernanda Laurinavicius and Ribeiro, Karina Braga, DDS, PhD and Rodriguez-Galindo, Carlos, MD
Journal of Pediatrics, The, ISSN 0022-3476, 2014, Volume 164, Issue 6, pp. 1481 - 1485
Objective To investigate trends in incidence of differentiated thyroid carcinomas among children and adolescents and young adults. Study design In this... 
Pediatrics | UNITED-STATES | CANCER INCIDENCE | NEW-CALEDONIA | RISK | IODINE | PEDIATRICS | SMOKING | PEOPLE | TRENDS | ENGLAND | HIGH-INCIDENCE AREA | United States - epidemiology | Confidence Intervals | SEER Program | Age Distribution | Prognosis | Risk Assessment | Humans | Thyroid Neoplasms - epidemiology | Child, Preschool | Infant | Male | Survival Rate | Incidence | Young Adult | Neoplasm Invasiveness - pathology | Adolescent | Sex Distribution | Female | Registries | Neoplasm Staging | Child | Thyroid Neoplasms - pathology | Health aspects | Thyroid diseases | Children
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