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Nature (London), ISSN 1476-4687, 2015, Volume 520, Issue 7548, pp. 553 - 557
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 36, pp. 11288 - 11293
Journal Article
Nature (London), ISSN 0028-0836, 2019, Volume 571, Issue 7764, pp. 270 - 270
Tumour-specific CD8 T cell dysfunction is a differentiation state that is distinct from the functional effector or memory T cell states(1-6). Here we identify... 
EFFECTOR | AUTOIMMUNITY | MULTIDISCIPLINARY SCIENCES | GENERATION | DYSFUNCTION | PROTEINS | PROMOTES | EXPRESSION | EXHAUSTION | PROGRAM | ANTIGEN | CD8-Positive T-Lymphocytes - cytology | CD8-Positive T-Lymphocytes - pathology | Epigenesis, Genetic | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | CD8-Positive T-Lymphocytes - metabolism | Lymphocytes, Tumor-Infiltrating - metabolism | Receptors, Antigen, T-Cell - immunology | Transcription, Genetic | Lymphocytes, Tumor-Infiltrating - cytology | High Mobility Group Proteins - metabolism | High Mobility Group Proteins - deficiency | Homeodomain Proteins - genetics | Cell Differentiation - immunology | Phenotype | Animals | Lymphocytes, Tumor-Infiltrating - pathology | Neoplasms - immunology | Immunologic Memory | Mice | CD8-Positive T-Lymphocytes - immunology | Neoplasms - pathology | High Mobility Group Proteins - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Physiological aspects | Genetic aspects | T cells | Cell differentiation | Tumors | Chromatin | Transcription factors | CD8 antigen | Differentiation (biology) | Chronic infection | Effector cells | Stimulation | Infections | Activation | Lymphocytes T | Genomes | NF-AT protein | Ovarian cancer | T-cell receptor | Liver cancer | Receptors | Cell activation | Clonal deletion | Listeria | Lymphocytes | Bioinformatics | Hepatocyte nuclear factor 1 | Deoxyribonucleic acid--DNA | Antigens | Data analysis | Immunological memory | Memory cells | Cloning | Melanoma | T cell receptors | Cell death | Exhaustion | Stem cells | Receptor mechanisms | Viral infections
Journal Article
PLoS biology, ISSN 1545-7885, 2006, Volume 4, Issue 6, pp. e187 - 1009
The genes encoding members of the wingless-related MMTV integration site ( WNT) and fibroblast growth factor ( FGF) families coordinate growth, morphogenesis,... 
DETERMINING REGION | NUCLEAR IMPORT | SERTOLI-CELL DIFFERENTIATION | TESTIS DIFFERENTIATION | FACTOR SOX9 | DEVELOPING GONAD | GERM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | BIOLOGY | EXPRESSION | CHONDROCYTE DIFFERENTIATION | Gonads - embryology | Sex-Determining Region Y Protein - genetics | Fibroblast Growth Factor 9 - physiology | Male | Wnt Proteins - metabolism | Fibroblast Growth Factor 9 - genetics | Gonads - cytology | Sex Determination Processes | Wnt Proteins - genetics | Gene Expression Regulation, Developmental | Female | Proto-Oncogene Proteins - metabolism | High Mobility Group Proteins - metabolism | Signal Transduction | Proto-Oncogene Proteins - genetics | Transcription Factors - genetics | Fibroblast Growth Factor 9 - metabolism | Transcription Factors - metabolism | Gonads - metabolism | Animals | Proto-Oncogene Proteins - physiology | Sex-Determining Region Y Protein - metabolism | Mice | Wnt Proteins - physiology | Mutation | SOX9 Transcription Factor | Wnt4 Protein | High Mobility Group Proteins - genetics | Cell culture | Experiments | Insulin | Embryos | Rodents | Genes | High Mobility Group Proteins | Sex-Determining Region Y Protein | Biochemistry, Molecular Biology | Wnt Proteins | Life Sciences | Transcription Factors | Proto-Oncogene Proteins | Gonads | Fibroblast Growth Factor 9 | Development | Mus (Mouse) | Vertebrates | Mammals | Cell Biology
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2014, Volume 146, Issue 4, pp. 1097 - 1107.e8
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2007, Volume 104, Issue 6, pp. 1865 - 1870
Journal Article
Molecular cell, ISSN 1097-2765, 2015, Volume 60, Issue 2, pp. 294 - 306
FACT, a heterodimer of Spt16 and Pob3, is an essential histone chaperone. We show that the H2A-H2B binding activity that is central to FACT function resides in... 
crystal structure | histone chaperone | histone binding | Spt16-Pob3 | nucleosome reorganization | Histone chaperone | Histone binding | Nucleosome reorganization | Crystal structure | SYSTEM | DOMAIN | CHROMATIN | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | HISTONE CHAPERONE | SPT16 | CORE PARTICLE | DNA-REPLICATION | FEATURES | CELL BIOLOGY | Transcription Factors - chemistry | Histones - chemistry | Nucleosomes - chemistry | Saccharomyces cerevisiae - genetics | Protein Multimerization | Transcriptional Elongation Factors - chemistry | Molecular Sequence Data | Crystallography, X-Ray | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Conserved Sequence | Transcriptional Elongation Factors - genetics | Gene Expression Regulation, Fungal | High Mobility Group Proteins - metabolism | High Mobility Group Proteins - chemistry | Models, Molecular | Nucleosomes - metabolism | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Amino Acid Motifs | Transcription Factors - metabolism | Transcriptional Elongation Factors - metabolism | Sequence Alignment | Histones - genetics | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Histones - metabolism | High Mobility Group Proteins - genetics | Saccharomyces cerevisiae Proteins - chemistry | Peptides | Analysis | Chemical properties | Medical colleges | Structure | Crystals
Journal Article