X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2491) 2491
Newsletter (268) 268
Publication (136) 136
Book Review (37) 37
Newspaper Article (30) 30
Book Chapter (10) 10
Conference Proceeding (4) 4
Reference (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
histamine (1454) 1454
animals (1094) 1094
pharmacology & pharmacy (1017) 1017
male (808) 808
humans (731) 731
rats (524) 524
index medicus (492) 492
histamine - pharmacology (420) 420
neurosciences (401) 401
female (381) 381
histamine h1 antagonists - pharmacology (378) 378
mice (337) 337
receptors (292) 292
histamine h-1 receptor (270) 270
immunology (252) 252
receptor (249) 249
dose-response relationship, drug (244) 244
research (243) 243
release (241) 241
brain (229) 229
biochemistry & molecular biology (226) 226
allergy (212) 212
histamine receptors (209) 209
histamine antagonists - pharmacology (198) 198
receptors, histamine h1 - metabolism (195) 195
adult (188) 188
antihistamines (183) 183
physiology (181) 181
inhibition (174) 174
in vitro techniques (168) 168
histamine - metabolism (167) 167
mast-cells (164) 164
rat (160) 160
activation (158) 158
rats, wistar (158) 158
expression (155) 155
histamine h2 antagonists - pharmacology (154) 154
guinea pigs (151) 151
pyrilamine - pharmacology (151) 151
histamine - physiology (147) 147
h-1 receptor (143) 143
antagonists (137) 137
histamine agonists - pharmacology (132) 132
rats, sprague-dawley (132) 132
histamine h (127) 127
inflammation (126) 126
neurons (124) 124
chemistry, medicinal (123) 123
cimetidine - pharmacology (120) 120
histamine h1 antagonists - therapeutic use (120) 120
analysis (118) 118
cells, cultured (116) 116
cell biology (115) 115
responses (114) 114
middle aged (113) 113
h-1 (111) 111
receptors, histamine - metabolism (108) 108
cells (107) 107
pharmacology (107) 107
allergic rhinitis (106) 106
ligands (105) 105
reports (105) 105
asthma (102) 102
double-blind (102) 102
cetirizine (101) 101
guinea-pig (100) 100
antagonist (99) 99
antihistamine (99) 99
universities and colleges (99) 99
rat-brain (98) 98
brain histamine (96) 96
drugs (95) 95
in-vitro (94) 94
receptors, histamine h1 - drug effects (94) 94
piperidines - pharmacology (92) 92
binding (89) 89
double-blind method (83) 83
physiological aspects (83) 83
calcium - metabolism (82) 82
histidine-decarboxylase (82) 82
psychiatry (81) 81
time factors (80) 80
receptors, histamine h1 - physiology (78) 78
histamine h-1 receptors (77) 77
terfenadine (77) 77
medicine, research & experimental (76) 76
disease models, animal (75) 75
toxicology (75) 75
cimetidine (74) 74
chlorpheniramine - pharmacology (73) 73
h-1 receptors (73) 73
muscle contraction - drug effects (73) 73
kinetics (72) 72
mast cells (72) 72
skin (72) 72
modulation (71) 71
receptors, histamine - physiology (71) 71
serotonin (71) 71
smooth-muscle (68) 68
loratadine (67) 67
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2759) 2759
Japanese (10) 10
German (8) 8
Spanish (4) 4
Croatian (3) 3
French (3) 3
Polish (3) 3
Chinese (2) 2
Czech (1) 1
Russian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 02/2007, Volume 104, Issue 9, pp. 3456 - 3459
The atypical antipsychotic drugs (AAPDs) have markedly enhanced the treatment of schizophrenias but their use has been hindered by the major weight gain... 
CLOZAPINE | HOMEOSTASIS | FOOD-INTAKE | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | SCHIZOPHRENIA | ATYPICAL ANTIPSYCHOTICS | atypical antipsychotic drugs | NEURONAL HISTAMINE | CENTRAL-NERVOUS-SYSTEM | OLANZAPINE | obesity | hypothalamus | BRAIN
Journal Article
by Kang, SK and Nam, DH and Ahn, J and Lee, J and Sim, J and Suh, YG
MOLECULES, ISSN 1420-3049, 11/2017, Volume 22, Issue 11
A practical and sustainable method for the synthesis of levocabastine hydrochloride (1), a H-1 receptor antagonist for the treatment of allergic... 
ALCOHOLS | CLONING | BIOCHEMISTRY & MOLECULAR BIOLOGY | SULFONAMIDES | H-1 receptor antagonist | anti-histamine | levocabastine | CHEMISTRY, MULTIDISCIPLINARY | HISTAMINE-RECEPTOR
Journal Article
EUROPEAN JOURNAL OF PHARMACOLOGY, ISSN 0014-2999, 04/2016, Volume 777, pp. 124 - 128
In this study, we examined the interaction between histamine H-1 receptor and mu-opioid receptor in scratching behavior in ICR mice. Both histamine and... 
Scratching behavior | ANTIHISTAMINES | PRURITUS | MAST-CELLS | Morphine | INDUCTION | Histamine | ATOPIC-DERMATITIS | Chlorpheniramine | Naloxone | NALTREXONE | PHARMACOLOGY & PHARMACY | ITCH-ASSOCIATED RESPONSES | SEROTONIN | ICR mice | ANTAGONISTS
Journal Article
DIABETES, ISSN 0012-1797, 09/2004, Volume 53, Issue 9, pp. 2250 - 2260
Histamine H-1 receptors (H-1-Rs) are found in peripheral tissues and in regions of the hypothalamus that are concerned. with regulating body composition. In... 
TARGETED DISRUPTION | MESSENGER-RNA | SUPRACHIASMATIC NUCLEUS | UNCOUPLING PROTEIN | FOOD-INTAKE | CIRCADIAN-RHYTHMS | BRAIN HISTAMINE | ENDOCRINOLOGY & METABOLISM | VISCERAL ADIPOSITY | BROWN ADIPOSE-TISSUE | CENTRAL LEPTIN INFUSION
Journal Article
JOURNAL OF NEUROCHEMISTRY, ISSN 0022-3042, 01/2018, Volume 144, Issue 1, pp. 68 - 80
G(q/11) protein-coupled human histamine H-1 receptors in Chinese hamster ovary cells stimulated with histamine undergo clathrin-dependent endocytosis followed... 
PROTEIN-KINASE-C | CALPAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRAFFICKING | NEUROSCIENCES | CA2+/CALMODULIN-MEDIATED REGULATION | MG ASTROCYTOMA-CELLS | PROTEASOME ACTIVITIES | Ca2 | ionomycin | BETA-ARRESTINS | endocytosis | internalization | down-regulation | histamine H-1 receptor | INHIBITORS | CLATHRIN-MEDIATED INTERNALIZATION
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2016, Volume 113, Issue 19, pp. E2714 - E2720
Retrieval represents a dynamic process that may require neuromodulatory signaling. Here, we report that the integrity of the brain histaminergic system is... 
Memory|retrieval | Inhibitory avoidance, histamine , h1 receptor | memory | histamine | FEAR MEMORY | inhibitory avoidance | MULTIDISCIPLINARY SCIENCES | PROTEIN-SYNTHESIS | H1 receptor | CONSOLIDATION | retrieval | SPATIAL MEMORY | MICE | EXTINCTION | BRAIN | PARTICIPATION | MODULATION | MOLECULAR-MECHANISMS
Journal Article
by Ma, WN and Zhang, DD and Li, J and Che, DL and Liu, R and Zhang, J and Zhang, YM
JOURNAL OF PHARMACY AND PHARMACOLOGY, ISSN 0022-3573, 11/2015, Volume 67, Issue 11, pp. 1567 - 1574
ObjectivesA high histamine H-1 receptor (H1R) expression cell membrane chromatography (CMC) method was developed to investigate the affinity of ligands for... 
H1 RECEPTOR | frontal analysis | drug-receptor interactions | dissociation equilibrium constant | GROWTH | DRUGS | PHARMACOLOGY & PHARMACY | cell membrane chromatography | histamine H-1 receptor | PERFORMANCE AFFINITY-CHROMATOGRAPHY | PROTEIN-BINDING
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ISSN 0960-894X, 01/2016, Volume 26, Issue 2, pp. 292 - 300
Distinct diaminopyrimidines, for example, 4-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[h]quinazolin-2-amine are histamine H-4 receptor (H4R) antagonists and... 
CHEMISTRY, MEDICINAL | PROTEIN | ANTAGONIST | Molecular dynamics | CHEMISTRY, ORGANIC | CLASSIFICATION | Diaminopyrimidines | AGONIST BINDING | MUTATIONAL ANALYSIS | Histamine H-4 receptor | Histamine H-1 receptor | INTERNATIONAL UNION | INFLAMMATION | RECEPTOR LIGANDS | PHARMACOLOGICAL PROFILE | MOLECULAR-CLONING | Dual H1R/H4R ligands
Journal Article
Molecular Immunology, ISSN 0161-5890, 07/2019, Volume 111, pp. 118 - 127
Phenothiazines are a class of antipsychotics that share the same tricyclic structure and are widely used in clinical settings. Adverse reactions from these... 
Pseudo-allergic reactions | H | Mast cell | receptor antagonist | MRGPRX2 | Phenothiazine antipsychotics | BIOCHEMISTRY & MOLECULAR BIOLOGY | CLASSIFICATION | SCHIZOPHRENIA | MECHANISMS | IMMUNOLOGY | DRUGS | INDUCED EXTRAPYRAMIDAL SYMPTOMS | H-1 receptor antagonist | ANAPHYLACTOID REACTIONS | HISTAMINE | HYPERSENSITIVITY
Journal Article
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, ISSN 0028-1298, 03/2014, Volume 387, Issue 3, pp. 235 - 250
Astemizole, a H1R antagonist shows high affinity to the histamine H-1 receptor but only a moderate affinity to the histamine H-4 receptor. This study aims to... 
ANTAGONIST | PROTEIN | Molecular dynamics | HIGH-AFFINITY | AGONIST BINDING | N-TERMINUS | SITE-DIRECTED MUTAGENESIS | MUTATIONAL ANALYSIS | Astemizole | Histamine H-4 receptor | Histamine H-1 receptor | INTERNATIONAL UNION | JNJ7777120 | PHARMACOLOGY & PHARMACY | MOLECULAR-CLONING | Dual H1R/H4R ligands | H-1-RECEPTOR AGONISTS
Journal Article
NEUROSCIENCE LETTERS, ISSN 0304-3940, 03/2018, Volume 668, pp. 60 - 66
The present study elucidated the role of histamine HI receptor in the caffeine induced locomotor sensitization. Intermittent administration of caffeine (15... 
SLEEP | POSTERIOR HYPOTHALAMUS | H-1 receptor | BEHAVIORAL SENSITIZATION | RATS | TUBEROMAMMILLARY NUCLEUS | NEUROSCIENCES | Histamine | TRANSMISSION | ADENOSINE A(2A) RECEPTORS | NEURONS | MICE | Locomotor sensitization | EXPRESSION | Caffeine
Journal Article
AMERICAN JOURNAL OF CHINESE MEDICINE, ISSN 0192-415X, 2018, Volume 46, Issue 1, pp. 55 - 68
This study investigated the influence of the histamine H-1 receptor antagonists, chlorpheniramine (CHL) and pyrilamine, on the analgesic effects of acupuncture... 
NERVOUS-SYSTEM | Electroacupuncture | Phospho-p38 | RATS | SPINAL-CORD | ANTINOCICEPTION | SCRATCHING BEHAVIOR | Analgesia | Histamine | MEDICINE, GENERAL & INTERNAL | Acetic Acid | Chlorpheniramine | PAIN | OPIOID RECEPTOR | INTEGRATIVE & COMPLEMENTARY MEDICINE | MICE | ACUPUNCTURE ANALGESIA | Pyrilamine | KNEE OSTEOARTHRITIS
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 10/2016, Volume 59, Issue 19, pp. 9047 - 9061
Journal Article
BONE, ISSN 8756-3282, 11/2013, Volume 57, Issue 1, pp. 269 - 271
It remains unknown why proton pump inhibitor (PPI) use may be associated with risk of osteoporotic fractures; evidence of direct effects on calcium absorption... 
Osteoporosis | Histamine | Antihistamines | Fractures | THERAPY | CALCIUM | ENDOCRINOLOGY & METABOLISM | Proton-pump inhibitors | Epidemiology
Journal Article
JOURNAL OF PHYSIOLOGY-LONDON, ISSN 0022-3751, 03/2005, Volume 563, Issue 2, pp. 633 - 642
In normally active individuals, postexercise hypotension after a single bout of aerobic exercise is due to an unexplained peripheral vasodilatation. Histamine... 
REFLEX VASODILATATION | TREADMILL EXERCISE | PHYSIOLOGY | REGIONAL HEMODYNAMICS | SYMPATHETIC-NERVE ACTIVITY | NITRIC-OXIDE | HUMANS | PHYSICAL-ACTIVITY | BLOOD-FLOW | NEUROSCIENCES | HISTAMINE-RECEPTOR | PLASMA HISTAMINE
Journal Article
EXPERT OPINION ON DRUG SAFETY, ISSN 1474-0338, 02/2015, Volume 14, Issue 2, pp. 199 - 206
Journal Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 01/2008, Volume 324, Issue 1, pp. 60 - 71
There are differences in the pharmacological properties of phenylhistamines and histaprodifens between guinea pig histamine H-1 receptor (gpH(1)R) and human... 
ACTIVATION | IN-VITRO EVALUATION | CLONING | PHARMACOLOGY & PHARMACY | GUINEA-PIG | BINDING POCKET | HISTAMINE H-1 RECEPTOR | SITE-DIRECTED MUTAGENESIS | MUTATIONAL ANALYSIS | G-PROTEIN | H-1-RECEPTOR AGONISTS
Journal Article
EUROPEAN NEUROPSYCHOPHARMACOLOGY, ISSN 0924-977X, 10/2015, Volume 25, Issue 10, pp. 1556 - 1565
Pharmacodynamic mechanisms of diabetes induced by antipsychotic drugs remain unclear, while numerous receptors have been suspected to be involved in the... 
COMPETITION BIAS | LEPTIN | Serotonin 5-HT2C | METABOLIC SYNDROME | PSYCHIATRY | INVOLVEMENT | SCHIZOPHRENIA | RISK | Pharmacovigilance | ADVERSE DRUG-REACTIONS | NEUROSCIENCES | ATYPICAL ANTIPSYCHOTICS | CLINICAL NEUROLOGY | RESEARCH DATABASE | Pharmacoepidemiology | Histamine H1 | Antipsychotics | OBESITY | PHARMACOLOGY & PHARMACY | Diabetes
Journal Article
PHARMACOLOGICAL RESEARCH, ISSN 1043-6618, 09/2016, Volume 111, pp. 679 - 687
Ligand residence time is thought to be a critical parameter for optimizing the in vivo efficacy of drug candidates. For the histamine H-1 receptor (H1R) and... 
BRET | MOLECULAR-MECHANISM | Residence time | Bioluminescence resonance energy-transfer | PHARMACOLOGICAL CHARACTERIZATION | PROTEIN-COUPLED RECEPTORS | RESONANCE ENERGY-TRANSFER | Arrestin | BETA-ARRESTIN | Histamine H-1 receptor | Binding rate | NUCLEAR-FACTOR | PARTIAL AGONIST | IN-VIVO | PHARMACOLOGY & PHARMACY | BETA-ADRENERGIC RECEPTOR
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.