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Circulation, ISSN 0009-7322, 03/2014, Volume 129, Issue 10, pp. 1139 - 1151
Journal Article
Cancer Research, ISSN 0008-5472, 02/2006, Volume 66, Issue 3, pp. 1277 - 1281
Journal Article
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 05/2013, Volume 9, Issue 5, pp. 319 - 325
Journal Article
Nature Medicine, ISSN 1078-8956, 11/2007, Volume 13, Issue 11, pp. 1299 - 1307
Journal Article
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2005, Volume 62, Issue 1, pp. 223 - 229
Histone deacetylase (HDAC) inhibitors, which modulate chromatin structure and gene expression, represent a class of anticancer agents that hold particular... 
Radiation sensitizer | Histone deacetylase (HDAC) inhibition | Suberoylanilide hydroxamic acid (SAHA) | CANCER-CELLS | C-ABL | radiation sensitizer | DEPENDENT PROTEIN-KINASE | DOUBLE-STRAND BREAKS | TUMOR-CELLS | GROWTH-FACTOR RECEPTOR | ONCOLOGY | IN-VIVO | historic deacetylase (HDAC) inhibition | HOMOLOGOUS RECOMBINATION | IONIZING-RADIATION | DNA-REPAIR | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Prostatic Neoplasms - radiotherapy | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Receptor, Epidermal Growth Factor - drug effects | Male | Glioma - radiotherapy | Receptor, Epidermal Growth Factor - metabolism | Caspases - metabolism | Glioma - pathology | Tumor Cells, Cultured | Hydroxamic Acids - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Cell Survival - drug effects | Prostatic Neoplasms - pathology | Proto-Oncogene Proteins - drug effects | Glioma - enzymology | Radiation-Sensitizing Agents - pharmacology | Enzyme Inhibitors - pharmacology | Cell Division - radiation effects | Cell Survival - radiation effects | Cell Division - drug effects | Proto-Oncogene Proteins c-akt | Radiation Tolerance - drug effects | Poly(ADP-ribose) Polymerases - metabolism | Protein-Serine-Threonine Kinases - drug effects | Prostatic Neoplasms - enzymology | Histone Deacetylase Inhibitors | DNA Damage | Drug Screening Assays, Antitumor | Index Medicus | GLIOMAS | PROSTATE | METHANOL | FLUORESCENCE SPECTROSCOPY | RIBOSE | TUMOR CELLS | DNA DAMAGES | GROWTH FACTORS | METHYL VIOLET | INHIBITION | RADIOLOGY AND NUCLEAR MEDICINE | RECEPTORS | FLUORESCEIN
Journal Article
Circulation Research, ISSN 0009-7330, 03/2012, Volume 110, Issue 5, pp. 739 - 748
Journal Article
Cancer Research, ISSN 0008-5472, 06/2006, Volume 66, Issue 12, pp. 6361 - 6369
Optimal reexpression of most genes silenced through promoter methylation requires the sequential application of DNA methyltransferase inhibitors followed by... 
ACUTE-LEUKEMIA | CYTIDINE DEAMINASE GENE | CPG ISLAND METHYLATION | ONCOLOGY | ARA-C SENSITIVITY | HYPOMETHYLATING AGENT | COLORECTAL-CANCER | RISK MYELODYSPLASTIC SYNDROME | LOW-DOSE 5-AZA-2'-DEOXYCYTIDINE | ORAL SODIUM PHENYLBUTYRATE | ELDERLY-PATIENTS | Azacitidine - adverse effects | Humans | Leukemia, Myeloid - genetics | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Phenylbutyrates - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Feasibility Studies | Myelodysplastic Syndromes - enzymology | Dose-Response Relationship, Drug | Phenylbutyrates - pharmacokinetics | Phenylbutyrates - administration & dosage | Aged, 80 and over | Female | Myelodysplastic Syndromes - drug therapy | Azacitidine - administration & dosage | Promoter Regions, Genetic | Acute Disease | Azacitidine - pharmacokinetics | Myelodysplastic Syndromes - metabolism | Histone Deacetylases - genetics | Leukemia, Myeloid - enzymology | Treatment Outcome | DNA (Cytosine-5-)-Methyltransferases - genetics | Leukemia, Myeloid - drug therapy | Acetylation - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Leukemia, Myeloid - metabolism | Aged | Histone Deacetylase Inhibitors | Myelodysplastic Syndromes - genetics | Histones - metabolism | DNA Methylation - drug effects | Index Medicus
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 03/2012, Volume 52, Issue 5, pp. 928 - 936
Interest in histone deacetylase (HDAC)-based therapeutics as a potential treatment for stroke has grown dramatically. The neuroprotection of HDAC inhibition... 
HDAC inhibition | Cerebral ischemia | TSA | Nrf2 | OXIDATIVE STRESS | SUBEROYLANILIDE HYDROXAMIC ACID | BRAIN-INJURY | ANTICANCER AGENTS | GINKGO-BILOBA | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURONAL CELL-DEATH | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | NRF2-MEDIATED ANTIOXIDANT RESPONSE | GENE-EXPRESSION | INTRACEREBRAL HEMORRHAGE | Neuroprotective Agents - therapeutic use | Cytoskeletal Proteins - genetics | Male | Luciferases - genetics | Cell Hypoxia | Neuroprotective Agents - pharmacology | Neurons - physiology | Cytoskeletal Proteins - metabolism | Female | NF-E2-Related Factor 2 - genetics | Neurons - drug effects | Hydroxamic Acids - pharmacology | Kelch-Like ECH-Associated Protein 1 | Genes, Reporter | Cell Survival - drug effects | Gene Expression | Response Elements | Mice, Inbred C57BL | Cells, Cultured | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Brain Ischemia - drug therapy | NF-E2-Related Factor 2 - metabolism | Adaptor Proteins, Signal Transducing - genetics | Brain Ischemia - pathology | Protein Binding | Histone Deacetylase Inhibitors - pharmacology | Hydroxamic Acids - therapeutic use | Histone Deacetylase Inhibitors - therapeutic use | Mice | Adaptor Proteins, Signal Transducing - metabolism | Luciferases - biosynthesis | Antioxidants | Cysteine | Surface active agents | Ligases | Heme | Histones | DNA binding proteins | Glucose | Sulfates | Glutamate | Dextrose | Phosphates | Glucose metabolism | Glutamate-cysteine ligase | Brain | Cell culture | Histone deacetylase | Neuroprotection | Oxygen | Stroke | Transcription factors | Neurons | Regulatory sequences | Nuclear transport | Ischemia | quinone oxidoreductase | Trichostatin A | Acetylation | Catalytic subunits | Index Medicus
Journal Article