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PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e47542 - e47542
Background: Mortality in the first months of antiretroviral therapy (ART) is a significant clinical problem in sub-Saharan Africa. To date, no post-mortem... 
AUTOPSY | RECONSTITUTION INFLAMMATORY SYNDROME | SUB-SAHARAN AFRICA | TUBERCULOSIS | MULTIDISCIPLINARY SCIENCES | HIV-POSITIVE PATIENTS | DISEASE | ADULTS | COHORT | EARLY MORTALITY | PATHOLOGY | Liver - virology | Tuberculosis, Pulmonary - microbiology | Liver - pathology | Kidney - pathology | Humans | Middle Aged | Male | Tuberculosis, Pulmonary - drug therapy | Bacterial Infections - virology | Liver - drug effects | Autopsy | HIV Infections - mortality | Lymph Nodes - drug effects | Bacterial Infections - microbiology | Bone Marrow - drug effects | Bone Marrow - virology | Kidney - drug effects | Bacterial Infections - drug therapy | HIV Infections - virology | Tuberculosis, Pulmonary - pathology | Tuberculosis, Pulmonary - mortality | Bacterial Infections - pathology | Lung - drug effects | Biopsy, Needle | Kidney - virology | Bacterial Infections - mortality | Mycobacterium tuberculosis - growth & development | Lymph Nodes - pathology | Mycobacterium tuberculosis - drug effects | Cause of Death | HIV - drug effects | Lung - virology | Immune Reconstitution Inflammatory Syndrome - virology | HIV Infections - pathology | Adult | Female | Skin - virology | Skin - pathology | Lung - pathology | South Africa - epidemiology | Lymph Nodes - virology | Immune Reconstitution Inflammatory Syndrome - mortality | HIV - growth & development | Antiretroviral Therapy, Highly Active | Immune Reconstitution Inflammatory Syndrome - pathology | Bone Marrow - pathology | Immune Reconstitution Inflammatory Syndrome - drug therapy | HIV Infections - drug therapy | Skin - drug effects | Tuberculosis, Pulmonary - virology | Antiviral agents | Bacterial infections | Mycobacterium tuberculosis | Dosage and administration | Diagnosis | Research | Drug therapy | Risk factors | Reproductive health | Health sciences | Therapy | Laboratories | Liver | Lung | Systematic review | Infections | Cerebrospinal fluid | Drug resistance | Lymph nodes | Acquired immune deficiency syndrome--AIDS | Antiretroviral agents | Human immunodeficiency virus--HIV | Bone marrow | Bacteria | Ultrasound | Spleen | Autopsies | Kidneys | Internal medicine | Mortality | Immune reconstitution | Inflammation | Patients | Antiretroviral therapy | Medicine | Hospitals | Tuberculosis | Infectious diseases | Lungs | Biopsy | Death | Fatalities | Adults | Skin | Bone | Kidney transplantation | Lymph | Index Medicus | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
Journal of Infectious Diseases, ISSN 0022-1899, 2015, Volume 212, Issue 10, pp. 1563 - 1573
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7484, pp. 509 - 514
The pathway causing CD4 T-cell death in HIV-infected hosts remains poorly understood although apoptosis has been proposed as a key mechanism. We now show that... 
APOPTOSIS | ACTIVATION | HUMAN LYMPHOID-TISSUE | DENDRITIC CELLS | MEMORY | REVERSE TRANSCRIPTION | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | X4 HIV-1 | EX-VIVO | CXCR4-TROPIC HIV-1 | Anti-HIV Agents - pharmacology | Spleen - virology | Inflammation - pathology | Caspase Inhibitors - pharmacology | HIV-1 - pathogenicity | Palatine Tonsil - drug effects | Inflammasomes - metabolism | Humans | Caspase 3 - metabolism | Caspase 1 - metabolism | Male | HIV Infections - enzymology | Spleen - drug effects | CD4-Positive T-Lymphocytes - pathology | Lymph Nodes - enzymology | HIV Infections - immunology | Inflammation - complications | HIV-1 - growth & development | HIV Infections - pathology | Adult | Interleukin-1beta - biosynthesis | Cell Death - drug effects | Interleukin-1beta - secretion | Caspase Inhibitors - administration & dosage | Administration, Oral | HIV-1 - drug effects | CD4-Positive T-Lymphocytes - cytology | Inflammation - virology | Inflammation - immunology | CD4-Positive T-Lymphocytes - secretion | Virus Replication | Protein Precursors - biosynthesis | Inflammasomes - immunology | Palatine Tonsil - virology | HIV Infections - drug therapy | In Vitro Techniques | CD4-Positive T-Lymphocytes - drug effects | Medical research | Cell death | Physiological aspects | Host-parasite relationships | Medicine, Experimental | Research | T cells | Health aspects | HIV infection | Infections | Kinases | Human immunodeficiency virus--HIV | Apoptosis | Immune system | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2015, Volume 11, Issue 9, pp. e1005153 - e1005153
Two of the crucial aspects of human immunodeficiency virus (HIV) infection are (i) viral persistence in reservoirs (precluding viral eradication) and (ii)... 
LONG-TERM NONPROGRESSORS | MESSENGER-RNA EXPRESSION | MICROBIOLOGY | NECROSIS-FACTOR-ALPHA | HUMAN-IMMUNODEFICIENCY-VIRUS | HUMAN ADIPOCYTES | VIROLOGY | ACTIVE ANTIRETROVIRAL THERAPY | SIVMAC251 INFECTION | IMMUNE ACTIVATION | METABOLIC-DISORDERS | MEMORY T-CELLS | PARASITOLOGY | Simian Acquired Immunodeficiency Syndrome - metabolism | HIV - physiology | Stromal Cells - pathology | Coculture Techniques | Humans | Middle Aged | Macaca fascicularis | Male | HIV - immunology | Adipose Tissue - immunology | CD4-Positive T-Lymphocytes - pathology | CD4-Positive T-Lymphocytes - immunology | Simian Immunodeficiency Virus - isolation & purification | Adipose Tissue - metabolism | HIV Infections - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Macrophages - virology | HIV Infections - pathology | Stromal Cells - virology | Adult | Female | Panniculitis - immunology | Disease Reservoirs | CD4-Positive T-Lymphocytes - virology | Simian Acquired Immunodeficiency Syndrome - pathology | Macrophages - immunology | Simian Immunodeficiency Virus - immunology | Macrophages - pathology | Adipose Tissue - virology | HIV Infections - virology | Stromal Cells - metabolism | Adipose Tissue - pathology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Stromal Cells - immunology | HIV - isolation & purification | Immunity, Innate | Panniculitis - virology | Simian Immunodeficiency Virus - physiology | Host-Pathogen Interactions | Macrophages - metabolism | Animals | Simian Acquired Immunodeficiency Syndrome - immunology | Aged | Panniculitis - pathology | Panniculitis - metabolism | HIV Infections - metabolism | Adipose tissues | Host-virus relationships | HIV (Viruses) | Simian immunodeficiency virus | Observations | Health aspects | Index Medicus | Life Sciences | Human health and pathology | Antiretroviral drugs | Lymphatic system | Mortality | Infections | Inflammation | Adipocytes | Metabolism | Experiments | HIV | Lymphocytes | Rodents | Deoxyribonucleic acid | DNA | Human immunodeficiency virus | Drug therapy
Journal Article
Immunity, ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 758 - 769
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 04/2002, Volume 8, Issue 4, pp. 379 - 385
Journal Article
Journal Article
Science, ISSN 0036-8075, 4/2013, Volume 340, Issue 6129, pp. 207 - 211
Journal Article