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Science, ISSN 0036-8075, 2/2008, Volume 319, Issue 5865, pp. 921 - 926
HIV-1 exploits multiple host proteins during infection. We performed a large-scale small interfering RNA screen to identify host factors required by HIV-1 and... 
T lymphocytes | HIV infections | HIV | Cell lines | Small interfering RNA | HeLa cells | Viruses | Infections | Genetic screening | Cells | Research Article | NUCLEAR IMPORT | COMPLEX | TRANSPORT | SNARE TLG1P | N-LINKED GLYCOSYLATION | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | GLYCOPROTEINS | CXCR4 | ENDOPLASMIC-RETICULUM | LATE GOLGI | HIV-1 - pathogenicity | Cytoskeletal Proteins - genetics | Human Immunodeficiency Virus Proteins - physiology | Genomics | Humans | rab GTP-Binding Proteins - genetics | Virus Internalization | Vesicular Transport Proteins - physiology | HIV-1 - physiology | RNA Interference | Transcription, Genetic | Cytoskeletal Proteins - physiology | Mediator Complex | Intracellular Signaling Peptides and Proteins - genetics | Proteins - physiology | HIV Infections - genetics | HIV Infections - virology | Vesicular Transport Proteins - genetics | Computational Biology | HIV-1 - genetics | Virus Integration | Karyopherins - physiology | Host-Pathogen Interactions | rab GTP-Binding Proteins - physiology | Virus Replication | Cell Line, Tumor | Karyopherins - genetics | RNA, Small Interfering | Intracellular Signaling Peptides and Proteins - physiology | HIV Infections - metabolism | Proteins | Gene targeting | RNA | Physiological aspects | Drug targeting | Genetic aspects | Research | Host-virus relationships | Properties | HIV infection | Health aspects | Biomedical research | Ribonucleic acid--RNA | Human immunodeficiency virus--HIV | Index Medicus
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 2015, Volume 125, Issue 10, pp. 1611 - 1622
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2015, Volume 290, Issue 45, pp. 27297 - 27310
Background: FACT proteins SUPT16H and SSRP1 are identified as host factors that restrict HIV-1 replication. Results: Biochemical and genetic evidences that... 
RNA-POLYMERASE-II | NEGATIVE ELONGATION-FACTOR | LONG TERMINAL REPEAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | POSTINTEGRATION LATENCY | IMMUNODEFICIENCY-VIRUS TYPE-1 | CHROMATIN DYNAMICS | CD4(+) T-CELLS | ANTIRETROVIRAL THERAPY | NF-KAPPA-B | P-TEFB | High Mobility Group Proteins - antagonists & inhibitors | Humans | Transcriptional Elongation Factors - antagonists & inhibitors | HIV Long Terminal Repeat | Human T-lymphotropic virus 1 - physiology | CD4-Positive T-Lymphocytes - physiology | Virus Latency - physiology | Cell Cycle Proteins - antagonists & inhibitors | HIV-1 - physiology | RNA Interference | HEK293 Cells | Cell Cycle Proteins - genetics | Human T-lymphotropic virus 1 - genetics | Transcriptional Elongation Factors - genetics | CD4-Positive T-Lymphocytes - virology | Cell Line | Promoter Regions, Genetic | DNA-Binding Proteins - physiology | Transcription Factors - physiology | DNA-Binding Proteins - antagonists & inhibitors | Transcriptional Elongation Factors - physiology | Transcription Factors - antagonists & inhibitors | Transcription Factors - genetics | DNA-Binding Proteins - genetics | HIV-1 - genetics | Cyclin T - physiology | Host-Pathogen Interactions - genetics | Models, Biological | High Mobility Group Proteins - physiology | Cell Cycle Proteins - physiology | Positive Transcriptional Elongation Factor B - physiology | High Mobility Group Proteins - genetics | Host-Pathogen Interactions - physiology | Virus Latency - genetics | Index Medicus | host-pathogen interaction | RNA interference (RNAi) | FACT complex | SUPT16H | Microbiology | human immunodeficiency virus (HIV) | viral transcription | latency | CD4 T cell | transcription repressor | SSRP1
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2013, Volume 73, Issue 5, pp. 443 - 453
Journal Article
Virology, ISSN 0042-6822, 2012, Volume 436, Issue 1, pp. 81 - 90
Abstract The human SAMHD1 protein is a novel retroviral restriction factor expressed in myeloid cells. Previous work has correlated the deoxynucleotide... 
Infectious Disease | HIV-1 | Restriction | HD domain | dNTPase | SAMHD1 | RNA binding | DNTPase | HIV-1 RESTRICTION | DENDRITIC CELLS | PARTICLES | MACROPHAGE INFECTION | NUCLEAR-LOCALIZATION | VPX PROTEIN | VIROLOGY | SIMIAN IMMUNODEFICIENCY VIRUS | MUTATIONS | PRIMATE LENTIVIRUSES | TRIM5-ALPHA | RNA-Binding Proteins - genetics | Retroviridae Infections - virology | Humans | SAM Domain and HD Domain-Containing Protein 1 | Green Fluorescent Proteins - genetics | Immunodeficiency Virus, Bovine - physiology | Leukemia Virus, Murine - physiology | Simian Immunodeficiency Virus - genetics | HIV-1 - physiology | Macrophages - virology | Retroviridae - genetics | U937 Cells | HEK293 Cells | HIV-2 - physiology | HIV-2 - genetics | Protein Interaction Domains and Motifs | RNA, Double-Stranded - metabolism | RNA, Viral - metabolism | Immunodeficiency Virus, Feline - physiology | Dendritic Cells - virology | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Cell Line | Retroviridae - physiology | HIV-1 - genetics | Monomeric GTP-Binding Proteins - antagonists & inhibitors | Infectious Anemia Virus, Equine - physiology | Monomeric GTP-Binding Proteins - metabolism | Monomeric GTP-Binding Proteins - chemistry | Simian Immunodeficiency Virus - metabolism | HeLa Cells | RNA-Binding Proteins - metabolism | Oligomers | Enzymes | RNA | Leukemia | High-definition television | HIV (Viruses) | Health aspects | Index Medicus
Journal Article
Journal Article