X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1198) 1198
amino acid sequence (513) 513
immunology (507) 507
hla-a2 antigen - immunology (504) 504
t-lymphocytes, cytotoxic - immunology (466) 466
animals (393) 393
index medicus (376) 376
molecular sequence data (373) 373
hla-a2 antigen - metabolism (338) 338
mice (299) 299
biochemistry & molecular biology (291) 291
hla-a2 antigen - chemistry (291) 291
peptides (266) 266
peptides - chemistry (256) 256
hla-a2 antigen - genetics (255) 255
protein binding (234) 234
major histocompatibility complex (231) 231
hla-a2 antigen (225) 225
cd8-positive t-lymphocytes - immunology (223) 223
peptides - immunology (223) 223
immunotherapy (212) 212
epitopes, t-lymphocyte - immunology (211) 211
female (209) 209
hla-a2 (208) 208
oncology (192) 192
identification (190) 190
cell line (189) 189
peptide fragments - immunology (189) 189
t cells (181) 181
lymphocytes (180) 180
antigen (179) 179
antigens, neoplasm - immunology (169) 169
epitopes (165) 165
male (164) 164
recognition (164) 164
models, molecular (158) 158
cell line, tumor (147) 147
antigens (145) 145
dendritic cells (144) 144
protein conformation (144) 144
binding (143) 143
peptide (143) 143
cancer (141) 141
expression (139) 139
mice, transgenic (138) 138
molecules (137) 137
histocompatibility antigens (136) 136
hla histocompatibility antigens (133) 133
antigen presentation (131) 131
t-lymphocytes - immunology (130) 130
tumor cells, cultured (130) 130
cytotoxicity, immunologic (128) 128
peptides - metabolism (126) 126
epitopes - immunology (124) 124
hla-a antigens - immunology (123) 123
flow cytometry (121) 121
base sequence (120) 120
peptide fragments - chemistry (120) 120
proteins (120) 120
melanoma - immunology (116) 116
research (116) 116
adult (110) 110
cell biology (109) 109
medicine, research & experimental (109) 109
epitopes - chemistry (108) 108
hematology (107) 107
transfection (107) 107
t-lymphocytes, cytotoxic - metabolism (104) 104
alleles (103) 103
binding sites (102) 102
middle aged (102) 102
cells (100) 100
neoplasm proteins - immunology (94) 94
multidisciplinary sciences (93) 93
cells, cultured (90) 90
antigens, neoplasm - chemistry (88) 88
protein (88) 88
vaccination (88) 88
epitopes, t-lymphocyte - chemistry (87) 87
complex (85) 85
melanoma (85) 85
peptide fragments - metabolism (85) 85
ctl (84) 84
mhc class-i (84) 84
antigenic determinants (81) 81
histocompatibility antigens class i - chemistry (81) 81
responses (81) 81
class-i molecules (80) 80
analysis (79) 79
cytotoxic t-lymphocytes (78) 78
receptors, antigen, t-cell - immunology (77) 77
article (76) 76
mhc (76) 76
crystallography, x-ray (75) 75
hla-a antigens - metabolism (75) 75
lymphocyte activation (75) 75
ligands (74) 74
hla-a antigens - chemistry (72) 72
mutation (72) 72
structure-activity relationship (72) 72
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2015, Volume 125, Issue 10, pp. 3981 - 3991
Adoptively transferred tumor-infiltrating T lymphocytes (TILs) that mediate complete regression of metastatic melanoma have been shown to recognize mutated... 
CD4+T CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | METASTATIC MELANOMA | TCR | THERAPY | RECOGNITION | ANTI-CTLA-4 | MUTATIONAL LANDSCAPE | CD4(+) | ANTIGENS | BLOCKADE | Humans | Middle Aged | Neoplasm Proteins - immunology | Molecular Sequence Data | Male | Antigen-Antibody Reactions | Epitopes - immunology | Exome | Melanoma - genetics | Peptide Fragments - immunology | Adult | Female | Receptor, ErbB-2 - immunology | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Transcription Factors - immunology | Amino Acid Sequence | Antigens, Neoplasm - genetics | DNA-Binding Proteins - immunology | HLA-A2 Antigen - immunology | Antigens, Neoplasm - immunology | Interferon-gamma Release Tests | Cells, Cultured | HLA-A1 Antigen - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Epitopes - genetics | Nuclear Proteins - immunology | Melanoma - secondary | HLA-A2 Antigen - chemistry | Algorithms | Genes, erbB-2 | Melanoma - immunology | Adolescent | RNA, Neoplasm - genetics | T-Cell Antigen Receptor Specificity | T-Lymphocytes - immunology | HLA-A1 Antigen - immunology | DNA, Neoplasm - genetics | Mutation | Antigens, Neoplasm - classification | Lymphocytes, Tumor-Infiltrating - immunology | Physiological aspects | T cells | Lymphocytes | Identification and classification | Health aspects | Tumors | Antigens | Peptides | Cloning | Melanoma | T cell receptors | Metastasis | Cancer therapies | Patients | Studies | Immunotherapy | Cancer
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2716 - 13
Foreign antigens are presented by antigen-presenting cells in the presence of abundant endogenous peptides that are nonstimulatory to the T cell. In mouse T... 
ACTIVATION | COMPLEX | RECOGNITION | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | SENSITIVITY | SELF | IMMUNOLOGICAL SYNAPSE | RECEPTORS | BINDING | MOLECULES | Recombinant Fusion Proteins - immunology | Receptors, Antigen, T-Cell - chemistry | HLA-A2 Antigen - genetics | Antigen-Presenting Cells - cytology | Cricetulus | Humans | Peptides - genetics | Epitopes - immunology | Signal Transduction - immunology | Transfection | Antigen Presentation | Receptors, Antigen, T-Cell - immunology | gag Gene Products, Human Immunodeficiency Virus - genetics | CHO Cells | T-Lymphocytes, Cytotoxic - immunology | Amino Acid Sequence | Gene Expression | Immunological Synapses - ultrastructure | HLA-A2 Antigen - immunology | Peptides - chemistry | Lymphocyte Activation | Peptides - immunology | Plasmids - immunology | Epitopes - genetics | Antigen-Presenting Cells - immunology | Antigens - chemistry | Animals | Immunological Synapses - immunology | Plasmids - chemistry | Recombinant Fusion Proteins - genetics | Antigens - immunology | Epitopes - chemistry | Receptors, Antigen, T-Cell - genetics | gag Gene Products, Human Immunodeficiency Virus - immunology | T-Lymphocytes, Cytotoxic - cytology | Antigens - genetics | Antigens | Phosphorylation | Peptides | CD8 antigen | Cytotoxicity | Lymphocytes T | T cell receptors | Epitopes | Molecular chains | CD4 antigen | T-cell receptor | Amplification | Signal transduction | Signaling | Major histocompatibility complex | Lymphocytes | Antigen-presenting cells | Human immunodeficiency virus--HIV | Histocompatibility antigen HLA | Human behavior
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 45, pp. 18618 - 18627
Influenza A virus (IAV) causes an acute infection in humans that is normally eliminated by CD8(+) cytotoxic T lymphocytes. Individuals expressing the MHC class... 
TCR | MEMORY REPERTOIRES | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISTINCT | RECEPTOR | ALPHA | MHC | surface plasmon resonance (SPR) | protein complex | FEATURES | T-cell receptor | major histocompatibility complex (MHC) | EXPANSION | crystal structure | influenza virus | epitope | SELECTION | Antibody Diversity | HLA-A2 Antigen - genetics | Viral Matrix Proteins - genetics | Antigens, Viral - metabolism | Humans | Receptors, Antigen, T-Cell, alpha-beta - chemistry | Antigens, Viral - genetics | Epitopes, T-Lymphocyte - genetics | Clonal Deletion | Immunodominant Epitopes - metabolism | Antigen-Antibody Complex - genetics | Influenza A virus - immunology | Viral Matrix Proteins - metabolism | Antigen-Antibody Complex - metabolism | Immunodominant Epitopes - genetics | Recombinant Proteins - metabolism | T-Lymphocytes, Cytotoxic - immunology | Protein Conformation, alpha-Helical | Peptide Fragments - metabolism | Immunodominant Epitopes - chemistry | T-Lymphocytes, Cytotoxic - virology | Models, Molecular | Recombinant Proteins - chemistry | Antibody Affinity | Antigens, Viral - chemistry | Receptors, Antigen, T-Cell, alpha-beta - genetics | Epitopes, T-Lymphocyte - chemistry | HLA-A2 Antigen - chemistry | Peptide Fragments - chemistry | Influenza A virus - metabolism | Hydrogen Bonding | T-Lymphocytes, Cytotoxic - metabolism | Viral Matrix Proteins - chemistry | Antigen-Antibody Complex - chemistry | T-Cell Antigen Receptor Specificity | Protein Conformation | HLA-A2 Antigen - metabolism | Mutation | Receptors, Antigen, T-Cell, alpha-beta - metabolism | T-Lymphocytes, Cytotoxic - cytology | Epitopes, T-Lymphocyte - metabolism | Amino Acid Substitution | 60 APPLIED LIFE SCIENCES | Immunology
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 07/2014, Volume 177, Issue 1, pp. 47 - 63
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2015, Volume 194, Issue 7, pp. 3487 - 3500
TCR alpha- and beta-chains cooperatively recognize peptide -MHC complexes. It has been shown that a "chain-centric" TCR hemichain can, by itself, dictate... 
METASTATIC MELANOMA | CANCER REGRESSION | SELF-PEPTIDE | ENHANCED ANTITUMOR-ACTIVITY | T-CELL-RECEPTOR | HIGH-AFFINITY | ANTIGEN-PRESENTING CELLS | GENE-TRANSFER | IMMUNOLOGY | DIRECTED EVOLUTION | MOLECULAR-BASIS | Recombinant Fusion Proteins - immunology | T-Lymphocyte Subsets - immunology | Complementarity Determining Regions - genetics | Receptors, Antigen, T-Cell - chemistry | HLA-A2 Antigen - genetics | Humans | Protein Multimerization | Epitopes, T-Lymphocyte - genetics | Recombinant Fusion Proteins - metabolism | Complementarity Determining Regions - chemistry | MART-1 Antigen - metabolism | Peptide Fragments - immunology | Epitopes, T-Lymphocyte - immunology | Complementarity Determining Regions - metabolism | Peptide Fragments - genetics | MART-1 Antigen - chemistry | Amino Acid Sequence | Cell Line | Peptide Fragments - metabolism | Transduction, Genetic | HLA-A2 Antigen - immunology | Receptors, Antigen, T-Cell - metabolism | Immunophenotyping | Receptors, Antigen, T-Cell, alpha-beta - genetics | Epitopes, T-Lymphocyte - chemistry | HLA-A2 Antigen - chemistry | Peptide Fragments - chemistry | T-Lymphocyte Subsets - metabolism | MART-1 Antigen - genetics | Cell Line, Tumor | Protein Binding | Recombinant Fusion Proteins - genetics | Receptors, Antigen, T-Cell - genetics | Receptors, Antigen, T-Cell, alpha-beta - metabolism
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0135385
Constitutive cell surface expression of Human Leukocyte Antigen (HLA) class I antigens vary extremely from tissue to tissue and individual antigens may differ... 
SINGLE AMINO-ACID | COMPLEX | TAP | TUMOR ESCAPE | PEPTIDE-BINDING | TAPASIN | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | CLASS-I MOLECULES | IMMUNE RECOGNITION | LYMPHOCYTES | HLA-A3 Antigen - genetics | Recombinant Fusion Proteins - immunology | RNA, Messenger - immunology | HLA-A2 Antigen - genetics | Humans | HLA-A3 Antigen - chemistry | Molecular Sequence Data | HLA-A3 Antigen - immunology | HLA-B7 Antigen - immunology | Transfection | HEK293 Cells | HLA-B7 Antigen - chemistry | HLA-B8 Antigen - genetics | Protein Structure, Tertiary | Amino Acid Sequence | Interferon-gamma | HLA-A2 Antigen - immunology | HLA-B7 Antigen - genetics | Histocompatibility Testing | RNA, Messenger - genetics | Gene Expression Regulation | HLA-B8 Antigen - chemistry | Recombinant Fusion Proteins - chemistry | Plasmids - metabolism | HLA-A2 Antigen - chemistry | Alleles | HLA-B8 Antigen - immunology | Plasmids - chemistry | Recombinant Fusion Proteins - genetics | Infection | Allelomorphism | Histocompatibility antigens | Health aspects | HLA histocompatibility antigens | Stem cells | Post-transcription | Flow cytometry | Peptides | Gene regulation | Stem cell transplantation | Amino acids | Viruses | Transplantation | Cell surface | B7 antigen | Immunology | Human immunodeficiency virus--HIV | Post-translation | Antigens | Complications | Cloning | Molecular chains | Polymerase chain reaction | White blood cells | Plasmids | Histocompatibility antigen HLA | Cancer | HIV | Human immunodeficiency virus
Journal Article
European Journal of Immunology, ISSN 0014-2980, 02/2015, Volume 45, Issue 2, pp. 584 - 591
MHC anchor residue-modified "heteroclitic" peptides have been used in many cancer vaccine trials and often induce greater immune responses than the wild-type... 
TCR | T-cell | MART-1 | Cross-reactivity | Melanoma | Peptide-major histocompatibility complex | Surface plasmon resonance | Melan-A | Crystal structure | TCR-BINDING | RECOGNITION | RECEPTOR | CANCER-IMMUNOTHERAPY | SELF-ANTIGEN | IMMUNOLOGY | THERMODYNAMICS | COMPLEX CLASS-I | HUMAN-MELANOMA | TUMOR-REACTIVE CTL | VACCINES | HLA-A2 Antigen - genetics | Humans | Receptors, Antigen, T-Cell, alpha-beta - chemistry | Peptides - genetics | Molecular Sequence Data | Alanine - chemistry | Crystallography, X-Ray | Epitopes, T-Lymphocyte - genetics | Receptors, Antigen, T-Cell, alpha-beta - immunology | Alanine - genetics | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Epitopes, T-Lymphocyte - immunology | Leucine - genetics | MART-1 Antigen - chemistry | MART-1 Antigen - immunology | T-Lymphocytes, Cytotoxic - immunology | Amino Acid Sequence | Gene Expression | HLA-A2 Antigen - immunology | Peptides - chemistry | Peptides - immunology | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Receptors, Antigen, T-Cell, alpha-beta - genetics | Leucine - chemistry | HLA-A2 Antigen - chemistry | Recombinant Proteins - immunology | T-Lymphocytes, Cytotoxic - metabolism | Escherichia coli - genetics | MART-1 Antigen - genetics | Protein Binding | T-Lymphocytes, Cytotoxic - cytology | Epitopes, T-Lymphocyte - metabolism | Amino Acid Substitution | Histocompatibility antigens | Peptides | Analysis | HLA histocompatibility antigens | Crystals | T cells | Structure | Antigenic determinants | Medical research | T cell receptors | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2006, Volume 103, Issue 44, pp. 16412 - 16417
HLA-G is a nonclassical MHC class I (MHCI) molecule that can suppress a wide range of immune responses in the maternal-fetal interface. The human inhibitory... 
T lymphocytes | Proteins | Receptors | Surface areas | Amino acids | Ligands | Dimers | Leukocytes | Natural killer cells | Crystal structure | Immune suppression | MHC class I | Maternal-fetal interface | m-free MHC | COMPLEX | PROTEIN | maternal-fetal interface | DENDRITIC CELLS | betam-free MHC | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | HLA-B27 | CUTTING EDGE | DISEASE | crystal structure | INHIBITORY RECEPTOR | immune suppression | BINDING | MYELOMONOCYTIC CELLS | Surface Plasmon Resonance | Antigens, CD - immunology | Receptors, Immunologic - chemistry | Humans | Membrane Glycoproteins - chemistry | beta 2-Microglobulin - chemistry | HLA Antigens - genetics | beta 2-Microglobulin - immunology | Protein Structure, Quaternary | Nuclear Magnetic Resonance, Biomolecular | Antigens, CD - chemistry | Membrane Glycoproteins - immunology | Receptors, Immunologic - immunology | Protein Structure, Tertiary | HLA-A2 Antigen - immunology | Leukocyte Immunoglobulin-like Receptor B1 | Histocompatibility Antigens Class I - immunology | HLA Antigens - immunology | Models, Molecular | Histocompatibility Antigens Class I - genetics | HLA-G Antigens | HLA Antigens - chemistry | Histocompatibility Antigens Class I - chemistry | Membrane Glycoproteins - genetics | HLA-A2 Antigen - chemistry | HLA Antigens - classification | Histocompatibility Antigens Class I - classification | Protein Binding | Structural Homology, Protein | Receptors, Immunologic - genetics | Usage | Immunology | Research | Maternal-fetal exchange | Structure | Crystals | Biological Sciences | maternal–fetal interface | β2m-free MHC
Journal Article
Immunity, ISSN 1074-7613, 2009, Volume 31, Issue 6, pp. 885 - 896
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2019, Volume 73, Issue 5, pp. 1015 - 1027.e7
Journal Article