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Diabetes, ISSN 0012-1797, 04/2018, Volume 67, Issue 4, pp. 687 - 696
The signal peptide region of preproinsulin (PPI) contains epitopes targeted by HLA-A-restricted (HLA-A0201, A2402) cytotoxic T cells as part of the... 
MHC CLASS-I | MECHANISM | KILL BETA-CELLS | ENDOCRINOLOGY & METABOLISM | ER MEMBRANE | HLA-B | ANTIGEN PRESENTATION | TRIMS PRECURSORS | CATALYZED INTRAMEMBRANE PROTEOLYSIS | ONSET | CD8 T-CELLS | HLA-A11 Antigen - immunology | Minor Histocompatibility Antigens | Humans | Insulin - immunology | Endoplasmic Reticulum | Protective Factors | Epitopes - immunology | Aspartic Acid Endopeptidases - immunology | Diabetes Mellitus, Type 1 - immunology | T-Lymphocytes, Cytotoxic - immunology | Cell Line | Genetic Predisposition to Disease | HLA-A24 Antigen - immunology | HLA-A2 Antigen - immunology | Aminopeptidases | Risk Factors | HLA-B Antigens - immunology | Protein Precursors - immunology | Gene Knockout Techniques | Protein Sorting Signals | Protein Precursors - metabolism | Protein Transport | HLA-A Antigens - immunology | Insulin - metabolism | Aspartic Acid Endopeptidases - metabolism | In Vitro Techniques | Diagnosis | Research | Peptides | Gene expression | Type 1 diabetes | Endoplasmic reticulum | Peptidase | Pathogenesis | Diabetes mellitus | Antigen processing | Cytotoxicity | Diabetes mellitus (insulin dependent) | Lymphocytes T | TAP protein | Epitopes | Insulin | Preproinsulin | Alleles | Information processing | Signal peptide peptidase | Histocompatibility antigen HLA | Diabetes | Aminopeptidase | Cytoplasm | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Virology, ISSN 0022-538X, 05/2016, Volume 90, Issue 9, pp. 4771 - 4779
Journal Article
Cancer Science, ISSN 1347-9032, 11/2007, Volume 98, Issue 11, pp. 1803 - 1808
For the development of cancer vaccine therapies, we have searched for possible epitope peptides that can elicit cytotoxic T lymphocytes (CTL) to the TTK... 
BREAST-CANCER | CDNA MICROARRAY | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | GENOME-WIDE ANALYSIS | HUMAN-MELANOMA | EXPRESSION PROFILES | CLASS-I MOLECULES | HEPATOCELLULAR CARCINOMAS | CYTOTOXIC T-LYMPHOCYTES | ANTIGEN | RNA-Binding Proteins - genetics | Immunotherapy - methods | Protein-Tyrosine Kinases - metabolism | Humans | Antigens, Ly - genetics | Peptides - genetics | Lung Neoplasms - pathology | Protein-Tyrosine Kinases - immunology | Esophageal Neoplasms - pathology | Cell Cycle Proteins - immunology | Protein-Tyrosine Kinases - genetics | Peptides - metabolism | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Cell Cycle Proteins - genetics | Antigens, Ly - metabolism | Cytotoxicity Tests, Immunologic - methods | Epitopes, T-Lymphocyte - immunology | Esophageal Neoplasms - therapy | Protein-Serine-Threonine Kinases - metabolism | T-Lymphocytes, Cytotoxic - immunology | Amino Acid Sequence | Antigens, Neoplasm - genetics | Cell Line | GPI-Linked Proteins - immunology | HLA-A24 Antigen - immunology | Antigens, Neoplasm - immunology | Peptides - immunology | RNA-Binding Proteins - immunology | Cell Cycle Proteins - metabolism | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Lung Neoplasms - therapy | Esophageal Neoplasms - immunology | GPI-Linked Proteins - metabolism | Cancer Vaccines - immunology | Lung Neoplasms - immunology | Antigens, Ly - immunology | T-Lymphocytes, Cytotoxic - metabolism | Cell Line, Tumor | Protein-Serine-Threonine Kinases - immunology | Biomarkers, Tumor - genetics | Cytotoxicity, Immunologic - immunology | Biomarkers, Tumor - immunology | T-Lymphocytes, Cytotoxic - cytology | Epitopes, T-Lymphocyte - metabolism | RNA-Binding Proteins - metabolism | GPI-Linked Proteins - genetics | Care and treatment | Peptides | Lung cancer | MHC antibodies | HLA histocompatibility antigens | Histocompatibility antigens | Immunotherapy | Genetic research | Genetic aspects | Drug therapy | Esophageal cancer | Cancer | Antigenic determinants | Index Medicus
Journal Article
Journal of Immunotherapy, ISSN 1524-9557, 10/2016, Volume 39, Issue 8, pp. 306 - 315
Programmed death-ligand 1 (PD-L1) binds to programmed death-1 (PD-1) on activated T cells and contributes to T-cell exhaustion. PD-L1 expressed on... 
Dendritic cell | Programmed death-ligand 1 | Artificial antigen-presenting cell | Cytotoxic T lymphocyte | MEDICINE, RESEARCH & EXPERIMENTAL | DENDRITIC CELLS | programmed death-ligand 1 | artificial antigen-presenting cell | PERIPHERAL-BLOOD | CANCER-IMMUNOTHERAPY | IMMUNOLOGY | WILMS-TUMOR ANTIGEN | CLINICAL-APPLICATION | DOWN-MODULATION | cytotoxic T lymphocyte | ONCOLOGY | ADVANCED MELANOMA | B7 FAMILY | EXPRESSION | PD-1 | dendritic cell | B7-2 Antigen - genetics | B7-1 Antigen - genetics | Dendritic Cells - immunology | Humans | HLA-A24 Antigen - genetics | Antibodies, Blocking - pharmacology | Cytomegalovirus Infections - immunology | Phosphoproteins - metabolism | Antibodies, Viral - blood | HLA-A24 Antigen - metabolism | Peptide Fragments - immunology | Viral Matrix Proteins - metabolism | Antigen-Presenting Cells - transplantation | Wilms Tumor - metabolism | T-Lymphocytes, Cytotoxic - immunology | Immunotherapy, Adoptive - methods | Antigens, Neoplasm - immunology | Lymphocyte Activation | Programmed Cell Death 1 Receptor - metabolism | B7-1 Antigen - metabolism | Antigen-Presenting Cells - immunology | B7-H1 Antigen - immunology | B7-2 Antigen - metabolism | Cytomegalovirus - immunology | B7-H1 Antigen - metabolism | K562 Cells | Wilms Tumor - immunology | Dendritic Cells - transplantation | Apoptosis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, pp. e0150996 - e0150996
Journal Article
European Urology, ISSN 0302-2838, 2016, Volume 70, Issue 1, pp. 35 - 41
Journal Article
Clinical Immunology, ISSN 1521-6616, 2016, Volume 166-167, pp. 48 - 58
Abstract We designed a phase I trial to investigate the safety, immune responses and clinical benefits of a five-peptide cancer vaccine in combination with... 
Allergy and Immunology | Translational research | Five-peptide cancer vaccine | Cyclophosphamide | Regulatory T cells | INTERLEUKIN-2 | IMMUNE-RESPONSE | LUNG | TESTIS ANTIGENS | IMMUNOLOGY | EPITOPE-PEPTIDES | IDENTIFICATION | BREAST-CANCER | IMMUNOTHERAPY | COLORECTAL-CANCER | REGULATORY T-CELLS | Lung Neoplasms - drug therapy | Cyclophosphamide - administration & dosage | Colorectal Neoplasms - genetics | Humans | Middle Aged | HLA-A24 Antigen - genetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Epitopes - administration & dosage | Male | Cyclophosphamide - adverse effects | Peptides - administration & dosage | Dose-Response Relationship, Drug | Epitopes - immunology | Neoplasms - genetics | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Colorectal Neoplasms - drug therapy | Leukopenia - chemically induced | Aged, 80 and over | Adult | Female | Vaccines, Subunit - adverse effects | Lung Neoplasms - genetics | Stomach Neoplasms - genetics | HLA-A24 Antigen - immunology | Drug Administration Schedule | Cancer Vaccines - administration & dosage | Peptides - immunology | Kaplan-Meier Estimate | Cancer Vaccines - adverse effects | Treatment Outcome | Cyclophosphamide - immunology | Vaccines, Subunit - immunology | Stomach Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - immunology | Neoplasms - drug therapy | Stomach Neoplasms - immunology | Cancer Vaccines - immunology | Lung Neoplasms - immunology | Colorectal Neoplasms - immunology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoplasms - immunology | Vaccines, Subunit - administration & dosage | T-Lymphocytes - immunology | Aged | Cancer vaccines | Antigens | Chemotherapy | Peptides | Vaccination | Colorectal cancer | Clinical trials | Product development | T cells | Cancer | Tumors | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 11/2011, Volume 17, Issue 21, pp. 6671 - 6680
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 01/2011, Volume 29, Issue 3, pp. 337 - 344
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 11/2013, Volume 3, Issue 1, pp. 3097 - 3097
Journal Article